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The map label for this gene is pcp [H]

Identifier: 146339681

GI number: 146339681

Start: 2877174

End: 2877845

Strand: Reverse

Name: pcp [H]

Synonym: BRADO2676

Alternate gene names: 146339681

Gene position: 2877845-2877174 (Counterclockwise)

Preceding gene: 146339682

Following gene: 146339679

Centisome position: 38.59

GC content: 68.75

Gene sequence:

>672_bases
TTGAGCGGGCGCGTCCGCATTCTGATCACCGGCTTCGGCCCGTTCCCCGGCGCACCAATCAACCCGACCATGCCGCTGGT
AAAGCGTCTGGCCGAGCTGCGGCGGCCCGCGCTCGACGATGCCGACGTCAGCAGCCACATCTTCCATGTCACCTACGCGA
CCGTCGATCGCGAGCTGCCTGCGCTGATCGCCGAGCGCCGCCCGCATGCGCTGCTGATGTTCGGACTCGCCGGACGAACC
TCCTATCTCCGCATCGAGACCCGCGCCCGCAACGCTATTACCACCACCTTCCCCGATGCCGACCGTCGCGTCGCCAGCAA
GGGTGTCATCGTGCCGGGCGCTCATCCCCTGGTCTTCGGCCCGCACATGGCGCGGCTGCTGCGCGCAGCGCGCGCCACCG
GCATCGACGCGAGGCCGTCCCGCGACGCAGGCAGCTATCTCTGCAACTATCTAAGCTGGCGAGCCATCGAGGCGACGCGG
GACGCGAACGGCCCGCGGCTCGCCGCCTTCATCCACATCCCTCCACTCCCCCGGGCGGGGACCGTGCTGCCGCACGGCAG
TTCGCGCATGACACTGGACGCGCTGGTGGACGCCGGCGAGGCGATGCTGATCGAGCTGATAAGGCTGGCGCGACAGGAAA
CCAGTCGCACCAGCCGAGATCGATCGAGCTGA

Upstream 100 bases:

>100_bases
ATCCCTCCATTCGCAGCAAGGTGAAGAAGCTCGAAACCGACGTCGCCGAAGGGCGCGTCGCGCCGGCGCTGGCCGCCGAG
CAGCTTGCGGAGATGCTGAA

Downstream 100 bases:

>100_bases
TGGCGGCCCAAATGGTCAGGCTCGCCATCAGCGGCTGACGTCAAGCGCTCCAGCGGCGTCGGCGGCCAAATCCGCCGCCG
ATCAGGCGCAGGATCAGCAA

Product: putative pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSGRVRILITGFGPFPGAPINPTMPLVKRLAELRRPALDDADVSSHIFHVTYATVDRELPALIAERRPHALLMFGLAGRT
SYLRIETRARNAITTTFPDADRRVASKGVIVPGAHPLVFGPHMARLLRAARATGIDARPSRDAGSYLCNYLSWRAIEATR
DANGPRLAAFIHIPPLPRAGTVLPHGSSRMTLDALVDAGEAMLIELIRLARQETSRTSRDRSS

Sequences:

>Translated_223_residues
MSGRVRILITGFGPFPGAPINPTMPLVKRLAELRRPALDDADVSSHIFHVTYATVDRELPALIAERRPHALLMFGLAGRT
SYLRIETRARNAITTTFPDADRRVASKGVIVPGAHPLVFGPHMARLLRAARATGIDARPSRDAGSYLCNYLSWRAIEATR
DANGPRLAAFIHIPPLPRAGTVLPHGSSRMTLDALVDAGEAMLIELIRLARQETSRTSRDRSS
>Mature_222_residues
SGRVRILITGFGPFPGAPINPTMPLVKRLAELRRPALDDADVSSHIFHVTYATVDRELPALIAERRPHALLMFGLAGRTS
YLRIETRARNAITTTFPDADRRVASKGVIVPGAHPLVFGPHMARLLRAARATGIDARPSRDAGSYLCNYLSWRAIEATRD
ANGPRLAAFIHIPPLPRAGTVLPHGSSRMTLDALVDAGEAMLIELIRLARQETSRTSRDRSS

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 24385; Mature: 24253

Theoretical pI: Translated: 11.62; Mature: 11.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRVRILITGFGPFPGAPINPTMPLVKRLAELRRPALDDADVSSHIFHVTYATVDRELP
CCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHH
ALIAERRPHALLMFGLAGRTSYLRIETRARNAITTTFPDADRRVASKGVIVPGAHPLVFG
HHHHCCCCCEEEEEECCCCCEEEEEEECCCCCEEECCCCHHHHHHHCCEECCCCCCEEEC
PHMARLLRAARATGIDARPSRDAGSYLCNYLSWRAIEATRDANGPRLAAFIHIPPLPRAG
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCEEEEEEECCCCCCCC
TVLPHGSSRMTLDALVDAGEAMLIELIRLARQETSRTSRDRSS
EECCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGRVRILITGFGPFPGAPINPTMPLVKRLAELRRPALDDADVSSHIFHVTYATVDRELP
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHH
ALIAERRPHALLMFGLAGRTSYLRIETRARNAITTTFPDADRRVASKGVIVPGAHPLVFG
HHHHCCCCCEEEEEECCCCCEEEEEEECCCCCEEECCCCHHHHHHHCCEECCCCCCEEEC
PHMARLLRAARATGIDARPSRDAGSYLCNYLSWRAIEATRDANGPRLAAFIHIPPLPRAG
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCEEEEEEECCCCCCCC
TVLPHGSSRMTLDALVDAGEAMLIELIRLARQETSRTSRDRSS
EECCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9756623; 11389725; 11432786 [H]