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The map label for this gene is fnrL [H]

Identifier: 146339315

GI number: 146339315

Start: 2443541

End: 2444212

Strand: Direct

Name: fnrL [H]

Synonym: BRADO2291

Alternate gene names: 146339315

Gene position: 2443541-2444212 (Clockwise)

Preceding gene: 146339314

Following gene: 146339318

Centisome position: 32.77

GC content: 65.77

Gene sequence:

>672_bases
ATGCTCGAGCAGGCGGTCCGTGGTCACATCCTGGTCGCGCCGGCCGGACAGGAATTGGCCCGCGAAGGAGACGCCGCGCT
CAGCGTCCTCATGATGCTGAGCGGCTGGGCCGCGCGCTATAAGATGCTGGAGGACGGCCGCCGACAGATCGTCAACCTTG
CGCTGCCCGGCGACACCTGTGATGCGCAGGTCTATTTCGTGAAGCGGCTCGATCATTCGATCGCGGCGCTGACGCCGGTC
AGCTACGCCGAACTCGACCGCGAGCGCTTCGAGAGCCTCATCGCGTGCGACCGCAGGCTGGCAGAAGCCTTCTGGTGCGA
GACGCTCTCCAATGCCGCGATCCAGCGCGAATGGACGCTGAACCTCGGCCGCCGCGACGCCTATGAGCGTGTCGCGCACC
TGCTGTGCGAGGTGATGACGCGGCTACGAACGGTCGGTCTGATCGACGGCGCCAGCTGCACCTTTCCGATCACGCAGACG
GATCTCGCCGACGCCACCGGCCTGTCGGTCGTTCACGTCAATCGCACTCTGCAAGAGCTGCGCTCCGCCGGCCTCATCGT
GCTGCGCGACCGGACGCTGACCGTGCCGGATTTCAAGGCGCTGATGGAGGCTGCGATGTTCGACCCCGAGTATCTGCATT
ACGGATCTCCGCATGACGCGTCGCCGGGTTGA

Upstream 100 bases:

>100_bases
CCGGCCAGCGATGAGCGGGCGCAGCATCAGTACGCACACGGCGGATGTCGTGCTTCGCCGGCTGCTTGCGTTCCGCGCGG
TCTCCGACGAGGCGGCCGCA

Downstream 100 bases:

>100_bases
ATGAATTCAGCTTGGACGCACGGGAAGAATTCGTGTGTCCCGGCGCGCCGCGCCGCATTCCCGCGCCTCGATGCAGGCGG
CTGCTGCGACGATCGAGGCG

Product: CRP/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MLEQAVRGHILVAPAGQELAREGDAALSVLMMLSGWAARYKMLEDGRRQIVNLALPGDTCDAQVYFVKRLDHSIAALTPV
SYAELDRERFESLIACDRRLAEAFWCETLSNAAIQREWTLNLGRRDAYERVAHLLCEVMTRLRTVGLIDGASCTFPITQT
DLADATGLSVVHVNRTLQELRSAGLIVLRDRTLTVPDFKALMEAAMFDPEYLHYGSPHDASPG

Sequences:

>Translated_223_residues
MLEQAVRGHILVAPAGQELAREGDAALSVLMMLSGWAARYKMLEDGRRQIVNLALPGDTCDAQVYFVKRLDHSIAALTPV
SYAELDRERFESLIACDRRLAEAFWCETLSNAAIQREWTLNLGRRDAYERVAHLLCEVMTRLRTVGLIDGASCTFPITQT
DLADATGLSVVHVNRTLQELRSAGLIVLRDRTLTVPDFKALMEAAMFDPEYLHYGSPHDASPG
>Mature_223_residues
MLEQAVRGHILVAPAGQELAREGDAALSVLMMLSGWAARYKMLEDGRRQIVNLALPGDTCDAQVYFVKRLDHSIAALTPV
SYAELDRERFESLIACDRRLAEAFWCETLSNAAIQREWTLNLGRRDAYERVAHLLCEVMTRLRTVGLIDGASCTFPITQT
DLADATGLSVVHVNRTLQELRSAGLIVLRDRTLTVPDFKALMEAAMFDPEYLHYGSPHDASPG

Specific function: Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 24789; Mature: 24789

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQAVRGHILVAPAGQELAREGDAALSVLMMLSGWAARYKMLEDGRRQIVNLALPGDTC
CCCCHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCC
DAQVYFVKRLDHSIAALTPVSYAELDRERFESLIACDRRLAEAFWCETLSNAAIQREWTL
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLGRRDAYERVAHLLCEVMTRLRTVGLIDGASCTFPITQTDLADATGLSVVHVNRTLQEL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHH
RSAGLIVLRDRTLTVPDFKALMEAAMFDPEYLHYGSPHDASPG
HHCCEEEEECCEECCHHHHHHHHHHHCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MLEQAVRGHILVAPAGQELAREGDAALSVLMMLSGWAARYKMLEDGRRQIVNLALPGDTC
CCCCHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCC
DAQVYFVKRLDHSIAALTPVSYAELDRERFESLIACDRRLAEAFWCETLSNAAIQREWTL
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLGRRDAYERVAHLLCEVMTRLRTVGLIDGASCTFPITQTDLADATGLSVVHVNRTLQEL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHH
RSAGLIVLRDRTLTVPDFKALMEAAMFDPEYLHYGSPHDASPG
HHCCEEEEECCEECCHHHHHHHHHHHCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]