Click here to switch to the map view.

The map label for this gene is ppiD [H]

Identifier: 146339260

GI number: 146339260

Start: 2377892

End: 2378917

Strand: Direct

Name: ppiD [H]

Synonym: BRADO2231

Alternate gene names: 146339260

Gene position: 2377892-2378917 (Clockwise)

Preceding gene: 146339259

Following gene: 146339261

Centisome position: 31.89

GC content: 70.37

Gene sequence:

>1026_bases
ATGACGGGGCCGCGCGCAACATTCCTTCTCGCTACGACGCTCTGCCTGGCGGCGGCGCAGGCATCTGCGCAGAGCCGCAC
GCCGGCCGCCGCGGCGACGCCGGCCCCGACCCGCGGCGCCGCGCCGGCGACGCCGCCCGCAGCGGCCAAGCCGGCCGCCG
GTGAGGAGCGGGGGGCGATCCGCAACGACGAGGTGGTCGCCCGCGTCGGCGACAGCGACGTCACGGCCGACGAGGTACGC
GCCACGATCGTGACGCTCGATCCGCGGCAGCAGGCGGCTTTGATGCGCGACCCCGCGCTGCTCAGCCAGACCGTCCGCGC
CATCCTCGCCAATCGGCTGGTGCTCAAGGAGGCGTTGGCCAAGAAGTGGGACCAGCAGCCGGCGGTCGTCGCGCAGCTTG
CGCGCGCCCGGGAGAGCATCCTCACGGAGGGTTACCTTCAGTCGGTGACGCAGCCGCCGGACTCCTACCCGAGCGAGGCG
GATATCAAGGCGGCCTATGAGGTCAACATGAGCGCGTTCCTGGTGCCGCGCCGCTTCCGCATTGCGCAGATTCTGGTCGC
GCTCGCCAATGATGCCGACAAGGCCGCTGAGGACGCCGCGAAGAAGAAGCTCGAAGACGTCGTCCGCAAGCTGAAGCAGC
CGGGAACCGACTTTGCCGCGCTGGCGCGGGCCAGTTCGGACGAGACGGCGACCGCGGAGAAGGACGGCGAGATCGGCTGG
GTGCCCGAGCCGAACCTGCGCGGCGAAATCCGCAGCCAGGTCGCAGGCCTCGCGAAGGGCGGCGTCACCGACCCGATCCG
GCTCGATGACGGTTGGCACGTCGTCAAGCTGCTCGACACGGATGCCTCGACCACGCGTCCGCTTGCCGAGGTCAAGGACG
TCCTGATCCAGCGGCTGCGCGCGGAGCGGGCCGACGCCAATCGCCGCGCCTATGTCGCGGAACTGGTCAAGCAGACGCCA
TCGGTCGTTAACGAGATCGCTCTGGGGCGGCTGTTCGGGGCCAAGCCGGAGACCGCGGCAAAATAA

Upstream 100 bases:

>100_bases
AGCTCTGGGATCACGAGCCGCTGACCGGGTTGAAGAGGGTCGAGCACCAGAACGCGGCCCAGGATTTCCGCGACCGAATT
CTCAATCAAAAGGTGAAGCC

Downstream 100 bases:

>100_bases
TCCTCGATCACCGCGGAACGGCGGGGAGTGGTCGCCGGCTCTCAAGAAGAGGGCGCTGGCGGGCAAGCGTGCGTCAGGCC
TATCGGCGCGCCCGCAGCCG

Product: putative peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTGPRATFLLATTLCLAAAQASAQSRTPAAAATPAPTRGAAPATPPAAAKPAAGEERGAIRNDEVVARVGDSDVTADEVR
ATIVTLDPRQQAALMRDPALLSQTVRAILANRLVLKEALAKKWDQQPAVVAQLARARESILTEGYLQSVTQPPDSYPSEA
DIKAAYEVNMSAFLVPRRFRIAQILVALANDADKAAEDAAKKKLEDVVRKLKQPGTDFAALARASSDETATAEKDGEIGW
VPEPNLRGEIRSQVAGLAKGGVTDPIRLDDGWHVVKLLDTDASTTRPLAEVKDVLIQRLRAERADANRRAYVAELVKQTP
SVVNEIALGRLFGAKPETAAK

Sequences:

>Translated_341_residues
MTGPRATFLLATTLCLAAAQASAQSRTPAAAATPAPTRGAAPATPPAAAKPAAGEERGAIRNDEVVARVGDSDVTADEVR
ATIVTLDPRQQAALMRDPALLSQTVRAILANRLVLKEALAKKWDQQPAVVAQLARARESILTEGYLQSVTQPPDSYPSEA
DIKAAYEVNMSAFLVPRRFRIAQILVALANDADKAAEDAAKKKLEDVVRKLKQPGTDFAALARASSDETATAEKDGEIGW
VPEPNLRGEIRSQVAGLAKGGVTDPIRLDDGWHVVKLLDTDASTTRPLAEVKDVLIQRLRAERADANRRAYVAELVKQTP
SVVNEIALGRLFGAKPETAAK
>Mature_340_residues
TGPRATFLLATTLCLAAAQASAQSRTPAAAATPAPTRGAAPATPPAAAKPAAGEERGAIRNDEVVARVGDSDVTADEVRA
TIVTLDPRQQAALMRDPALLSQTVRAILANRLVLKEALAKKWDQQPAVVAQLARARESILTEGYLQSVTQPPDSYPSEAD
IKAAYEVNMSAFLVPRRFRIAQILVALANDADKAAEDAAKKKLEDVVRKLKQPGTDFAALARASSDETATAEKDGEIGWV
PEPNLRGEIRSQVAGLAKGGVTDPIRLDDGWHVVKLLDTDASTTRPLAEVKDVLIQRLRAERADANRRAYVAELVKQTPS
VVNEIALGRLFGAKPETAAK

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=246, Percent_Identity=26.0162601626016, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 36300; Mature: 36168

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPRATFLLATTLCLAAAQASAQSRTPAAAATPAPTRGAAPATPPAAAKPAAGEERGAI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RNDEVVARVGDSDVTADEVRATIVTLDPRQQAALMRDPALLSQTVRAILANRLVLKEALA
CCCCCEEEECCCCCCHHHHEEEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
KKWDQQPAVVAQLARARESILTEGYLQSVTQPPDSYPSEADIKAAYEVNMSAFLVPRRFR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEECCHHEECCHHHH
IAQILVALANDADKAAEDAAKKKLEDVVRKLKQPGTDFAALARASSDETATAEKDGEIGW
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCC
VPEPNLRGEIRSQVAGLAKGGVTDPIRLDDGWHVVKLLDTDASTTRPLAEVKDVLIQRLR
CCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
AERADANRRAYVAELVKQTPSVVNEIALGRLFGAKPETAAK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TGPRATFLLATTLCLAAAQASAQSRTPAAAATPAPTRGAAPATPPAAAKPAAGEERGAI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RNDEVVARVGDSDVTADEVRATIVTLDPRQQAALMRDPALLSQTVRAILANRLVLKEALA
CCCCCEEEECCCCCCHHHHEEEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
KKWDQQPAVVAQLARARESILTEGYLQSVTQPPDSYPSEADIKAAYEVNMSAFLVPRRFR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEECCHHEECCHHHH
IAQILVALANDADKAAEDAAKKKLEDVVRKLKQPGTDFAALARASSDETATAEKDGEIGW
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCC
VPEPNLRGEIRSQVAGLAKGGVTDPIRLDDGWHVVKLLDTDASTTRPLAEVKDVLIQRLR
CCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
AERADANRRAYVAELVKQTPSVVNEIALGRLFGAKPETAAK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA