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The map label for this gene is exbB [H]

Identifier: 146339255

GI number: 146339255

Start: 2372259

End: 2374214

Strand: Direct

Name: exbB [H]

Synonym: BRADO2226

Alternate gene names: 146339255

Gene position: 2372259-2374214 (Clockwise)

Preceding gene: 146339254

Following gene: 146339256

Centisome position: 31.81

GC content: 66.51

Gene sequence:

>1956_bases
ATGACGCGCGTCAACGCCCGTCCGCGCCGCTCGCTGACCTGGAGTGGTCAGGCGATGTTGCTGATTGCACTCCTGATCAC
GTTGTGGCCGGGCAGCGCCTCGGCGTGGTGGAACGAGCAATGGACCCTGCGCAAGAAGATCACGATCGACACCGCGCCGA
CGGGCGCGGCGATCACCGACCCGATCGGTCTGACACCGGTGCTGGTGCGGCTGCATATCGGAAACTTCCGATTCGGCGCG
GCCAAGGACGATGGCGGCGACTTGCGCTTCGTCGCGGCGGACGACAAGACGCCGCTGAAGCATCACGTCGAGAAATACGA
TCCGCTGCTCGGTGAAGCCCTGGTCTGGGTCGGCGTGCCCGACCTCAAGCCCGGCGCGAAGAACGAGGTCTGGCTGTATT
ACGGCAATCAGAAAGCGCCGGCGGCGGTCGATGCCAAGGGCACCTATGATCAGGACACGGTGCTCGTGTATCATTTCGCC
GAGCGCGGCGGGCCGGCGCAGGACGTGTCGGCCTGGGCCAACGGCGCGCAGAGCGCGGTGCCGGCCGCCGACGGGGCCCT
CATCGGGCAGGGCGCGCGGTTCGACGGACAAACCTCGATCACGCTGCCCGGATCGCCATCGCTGGTCGTGGCCGAAGGCG
GCGAGCTCAGTTGGTCGGTTTGGGTCAAGATGGCCGCGCCGCAGCCGCGGGCGGTGCTTTACACCCGCTCGGAGGGGGCG
AACAGCTTCACGATTGGTCTCGACAATGGCGTGCCCTTTGTCGAGATCCTCAACAACGGCGCGACACAGCGCGCAAACGG
TGCGGCTGCGCTGGACGCCGGGACGTGGCGACACCTGGCCGTGACGGCCAAGAGCAACCAGGTGACGCTGTTCGTCGACG
GCAATCCCGTCGCGCCGATCCCAGCTGCGCTACCGACGATGACCGGGACCGCACAGATCGGGCGCGCGGTGCCGGCGGCC
AGCTCAGCGGCTGATGCCCCTTCCGCATCGGCTGTCGTGGCGCCGGCCGCGGATGCGCCCGCGGCTGCGTCTTCCGATCC
CGCCGCACCAGCTGCGGCGCCGCCGGCGGGCTTCGTTGGCGATATCGATGAACTGCAGATCGCCAAGGCCGCGCGTCCGG
CCGGCTTCATCAAGCTCGCGGCGATCGGCCAGGGGCCCGAGCAGGCCAAGCTGATCTCGTTCAGCGTCGACGAAGAGAAC
GCGAGCTGGCTGAGCGGCTACTTCGCGGTCATCCTGCGGTCGGTGACGCTCGACGGCTGGGTCGTGATCGGCCTGCTCGC
TGTGATGGCCGTGATCAGCTGGTTCGTGATGTACGATCGCGTCTCCTATCTCAACCGGATCTCGCGTGCCAACGCGACAT
TCCTCAAGCATTTCCGCGACGGCACGGTGGAAATATCCGAACTGTTGAGCGCCGATCAGCAGGACACCGATCTGTCGCTC
GGCGGCCGCATCACCAAGAAGAAGGAAACGCGAGCGCTGCAGCGCTCGCCGCTGTTCCGACTGTTCAATCTCGGCGCCGA
GCAGATCCGCCGCCGCTTCGCGCGTGGTCAGAGCAGCCTGTCAGGACCTGCTATCGAGTCGATCCGGGCAGTGTTGGACA
GCGGTTTCGTCCAGGAGACACAGCGGCTCAACCGCATGATGGTGATGCTGACCATCGCCATCTCTGGCGGACCGTTCCTC
GGCCTGCTCGGCACCGTGGTCGGCGTCATGATCACCTTCGCAGCGATCGCCGCCACGGGCGACGTGAACGTCAACGCGAT
CGCGCCCGGCATCGCCGCGGCCCTGGTCGCGACCGTGGCCGGCCTCGGCGTCGCGATCCCGGCGTTGTTCGCCTACAACT
ACCTCATCACGCGGATCAAGGATGCCACCAGTGAGATGCAGGTGTTCATCGACGAGATGATCACACGCATCGCCGAGACC
TATTCCGGCAACCACACGGCACAAGCAGCGGAGTGA

Upstream 100 bases:

>100_bases
CTTCAACGGAGTGTTCCTGATCGGAGTGCCGCTGATCAATCAGCAGGCCACGATCGTCAATCATCCGCGCTTCAGCTTTC
GTTTCTGGGGAGAGTTCTAG

Downstream 100 bases:

>100_bases
GGCGATGCAGGTCCAAACCGAAAGCAAGCCCTATGACGACATCAACATCACGCCGATGCTCGATCTTGCCTACGTCCTAC
TGGTGATCTTCATCATCATG

Product: biopolymer transport protein ExbB/TolQ family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 650

Protein sequence:

>651_residues
MTRVNARPRRSLTWSGQAMLLIALLITLWPGSASAWWNEQWTLRKKITIDTAPTGAAITDPIGLTPVLVRLHIGNFRFGA
AKDDGGDLRFVAADDKTPLKHHVEKYDPLLGEALVWVGVPDLKPGAKNEVWLYYGNQKAPAAVDAKGTYDQDTVLVYHFA
ERGGPAQDVSAWANGAQSAVPAADGALIGQGARFDGQTSITLPGSPSLVVAEGGELSWSVWVKMAAPQPRAVLYTRSEGA
NSFTIGLDNGVPFVEILNNGATQRANGAAALDAGTWRHLAVTAKSNQVTLFVDGNPVAPIPAALPTMTGTAQIGRAVPAA
SSAADAPSASAVVAPAADAPAAASSDPAAPAAAPPAGFVGDIDELQIAKAARPAGFIKLAAIGQGPEQAKLISFSVDEEN
ASWLSGYFAVILRSVTLDGWVVIGLLAVMAVISWFVMYDRVSYLNRISRANATFLKHFRDGTVEISELLSADQQDTDLSL
GGRITKKKETRALQRSPLFRLFNLGAEQIRRRFARGQSSLSGPAIESIRAVLDSGFVQETQRLNRMMVMLTIAISGGPFL
GLLGTVVGVMITFAAIAATGDVNVNAIAPGIAAALVATVAGLGVAIPALFAYNYLITRIKDATSEMQVFIDEMITRIAET
YSGNHTAQAAE

Sequences:

>Translated_651_residues
MTRVNARPRRSLTWSGQAMLLIALLITLWPGSASAWWNEQWTLRKKITIDTAPTGAAITDPIGLTPVLVRLHIGNFRFGA
AKDDGGDLRFVAADDKTPLKHHVEKYDPLLGEALVWVGVPDLKPGAKNEVWLYYGNQKAPAAVDAKGTYDQDTVLVYHFA
ERGGPAQDVSAWANGAQSAVPAADGALIGQGARFDGQTSITLPGSPSLVVAEGGELSWSVWVKMAAPQPRAVLYTRSEGA
NSFTIGLDNGVPFVEILNNGATQRANGAAALDAGTWRHLAVTAKSNQVTLFVDGNPVAPIPAALPTMTGTAQIGRAVPAA
SSAADAPSASAVVAPAADAPAAASSDPAAPAAAPPAGFVGDIDELQIAKAARPAGFIKLAAIGQGPEQAKLISFSVDEEN
ASWLSGYFAVILRSVTLDGWVVIGLLAVMAVISWFVMYDRVSYLNRISRANATFLKHFRDGTVEISELLSADQQDTDLSL
GGRITKKKETRALQRSPLFRLFNLGAEQIRRRFARGQSSLSGPAIESIRAVLDSGFVQETQRLNRMMVMLTIAISGGPFL
GLLGTVVGVMITFAAIAATGDVNVNAIAPGIAAALVATVAGLGVAIPALFAYNYLITRIKDATSEMQVFIDEMITRIAET
YSGNHTAQAAE
>Mature_650_residues
TRVNARPRRSLTWSGQAMLLIALLITLWPGSASAWWNEQWTLRKKITIDTAPTGAAITDPIGLTPVLVRLHIGNFRFGAA
KDDGGDLRFVAADDKTPLKHHVEKYDPLLGEALVWVGVPDLKPGAKNEVWLYYGNQKAPAAVDAKGTYDQDTVLVYHFAE
RGGPAQDVSAWANGAQSAVPAADGALIGQGARFDGQTSITLPGSPSLVVAEGGELSWSVWVKMAAPQPRAVLYTRSEGAN
SFTIGLDNGVPFVEILNNGATQRANGAAALDAGTWRHLAVTAKSNQVTLFVDGNPVAPIPAALPTMTGTAQIGRAVPAAS
SAADAPSASAVVAPAADAPAAASSDPAAPAAAPPAGFVGDIDELQIAKAARPAGFIKLAAIGQGPEQAKLISFSVDEENA
SWLSGYFAVILRSVTLDGWVVIGLLAVMAVISWFVMYDRVSYLNRISRANATFLKHFRDGTVEISELLSADQQDTDLSLG
GRITKKKETRALQRSPLFRLFNLGAEQIRRRFARGQSSLSGPAIESIRAVLDSGFVQETQRLNRMMVMLTIAISGGPFLG
LLGTVVGVMITFAAIAATGDVNVNAIAPGIAAALVATVAGLGVAIPALFAYNYLITRIKDATSEMQVFIDEMITRIAETY
SGNHTAQAAE

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG5306

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=213, Percent_Identity=27.6995305164319, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 68616; Mature: 68485

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVNARPRRSLTWSGQAMLLIALLITLWPGSASAWWNEQWTLRKKITIDTAPTGAAITD
CCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCC
PIGLTPVLVRLHIGNFRFGAAKDDGGDLRFVAADDKTPLKHHVEKYDPLLGEALVWVGVP
CCCCCEEEEEEEECCEEECCCCCCCCCEEEEECCCCCCHHHHHHHHCCHHHCEEEEEECC
DLKPGAKNEVWLYYGNQKAPAAVDAKGTYDQDTVLVYHFAERGGPAQDVSAWANGAQSAV
CCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCC
PAADGALIGQGARFDGQTSITLPGSPSLVVAEGGELSWSVWVKMAAPQPRAVLYTRSEGA
CCCCCCEECCCCCCCCCEEEEECCCCCEEEECCCCEEEEEEEEECCCCCCEEEEEECCCC
NSFTIGLDNGVPFVEILNNGATQRANGAAALDAGTWRHLAVTAKSNQVTLFVDGNPVAPI
CEEEEECCCCCCHHHHHCCCCCCCCCCCEEECCCCCEEEEEEECCCEEEEEECCCCCCCC
PAALPTMTGTAQIGRAVPAASSAADAPSASAVVAPAADAPAAASSDPAAPAAAPPAGFVG
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
DIDELQIAKAARPAGFIKLAAIGQGPEQAKLISFSVDEENASWLSGYFAVILRSVTLDGW
CHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCHH
VVIGLLAVMAVISWFVMYDRVSYLNRISRANATFLKHFRDGTVEISELLSADQQDTDLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEHHHHHCCCCCCCCCCC
GGRITKKKETRALQRSPLFRLFNLGAEQIRRRFARGQSSLSGPAIESIRAVLDSGFVQET
CCCCCCHHHHHHHHHCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHH
QRLNRMMVMLTIAISGGPFLGLLGTVVGVMITFAAIAATGDVNVNAIAPGIAAALVATVA
HHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
GLGVAIPALFAYNYLITRIKDATSEMQVFIDEMITRIAETYSGNHTAQAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TRVNARPRRSLTWSGQAMLLIALLITLWPGSASAWWNEQWTLRKKITIDTAPTGAAITD
CCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCC
PIGLTPVLVRLHIGNFRFGAAKDDGGDLRFVAADDKTPLKHHVEKYDPLLGEALVWVGVP
CCCCCEEEEEEEECCEEECCCCCCCCCEEEEECCCCCCHHHHHHHHCCHHHCEEEEEECC
DLKPGAKNEVWLYYGNQKAPAAVDAKGTYDQDTVLVYHFAERGGPAQDVSAWANGAQSAV
CCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCC
PAADGALIGQGARFDGQTSITLPGSPSLVVAEGGELSWSVWVKMAAPQPRAVLYTRSEGA
CCCCCCEECCCCCCCCCEEEEECCCCCEEEECCCCEEEEEEEEECCCCCCEEEEEECCCC
NSFTIGLDNGVPFVEILNNGATQRANGAAALDAGTWRHLAVTAKSNQVTLFVDGNPVAPI
CEEEEECCCCCCHHHHHCCCCCCCCCCCEEECCCCCEEEEEEECCCEEEEEECCCCCCCC
PAALPTMTGTAQIGRAVPAASSAADAPSASAVVAPAADAPAAASSDPAAPAAAPPAGFVG
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
DIDELQIAKAARPAGFIKLAAIGQGPEQAKLISFSVDEENASWLSGYFAVILRSVTLDGW
CHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCHH
VVIGLLAVMAVISWFVMYDRVSYLNRISRANATFLKHFRDGTVEISELLSADQQDTDLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEHHHHHCCCCCCCCCCC
GGRITKKKETRALQRSPLFRLFNLGAEQIRRRFARGQSSLSGPAIESIRAVLDSGFVQET
CCCCCCHHHHHHHHHCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHH
QRLNRMMVMLTIAISGGPFLGLLGTVVGVMITFAAIAATGDVNVNAIAPGIAAALVATVA
HHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
GLGVAIPALFAYNYLITRIKDATSEMQVFIDEMITRIAETYSGNHTAQAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9140974 [H]