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The map label for this gene is pdxH [H]

Identifier: 146339186

GI number: 146339186

Start: 2282549

End: 2283199

Strand: Reverse

Name: pdxH [H]

Synonym: BRADO2146

Alternate gene names: 146339186

Gene position: 2283199-2282549 (Counterclockwise)

Preceding gene: 146339189

Following gene: 146339185

Centisome position: 30.62

GC content: 65.9

Gene sequence:

>651_bases
ATGACCGACCCCACGAGCATCAAACACCAGACAACCTTAACATCCGGTACATCGGCTGATTTTACCCAGGCCGGGGAGCC
GTTTGCGCTGTTTGCCGAGTGGTTCGCCGAAGCCAGCAAGAGCGAGCCGAACGATCCGAACGCGATGGCGCTGTCGACCG
TGGACGCGGACGGCCTTCCGGATGTGCGCATGGTGCTGATGAAGGGCTACGACGCCGACGGCTTCGTCTTCTACAGCCAC
AAGGCCAGCCAGAAGGGCCAGGAGCTCGCCGCCAATCCAAAGGCCGCGTTGCTGTTTCATTGGAAGTCGCTGCGCCGGCA
GGTGCGCATCCGCGGGCTCGTGACGCCGGTGACGGACGCGGAGGCCGACGCCTATTTCGCGACCCGGCCGAAGCAGGCGC
AGCTCGGCGCCTGGGCCAGCAAGCAGTCGCAGCCGCTGGAGAGCCGGTTCGCCTTCGAACAGGCGATCGCCAAGGTCGCC
ACGCAATACATCATCGGCGAGGTGCCGCGTCCGCCGGGATGGAGCGGCTGGCGCATCACCCCCGTTCGCATGGAGTTCTG
GCACGACCGGCCGTTCCGCCTGCACGACCGCATCGAATTCCGGCGCGAGGCTGCCGGTCAGCCGTGGACCAAGGTGCGGA
TGTATCCGTAG

Upstream 100 bases:

>100_bases
GATAGGCCAAGCCGGACCGATACCCTATATAGGGCCGGACCAGAATGGACTTGCACGCGCCTGGCCGCGGGTGAACGCAA
AACTCGGACTCCCCAAAGAC

Downstream 100 bases:

>100_bases
CGACCGGCGAGGCTCCGTTGAGTCTCATCGTCAACTTGTCGCTCGACAGCCTTCGACGTCGGTGCGCATGAAACGCGCAC
CGAACATGCAACCCTTGTGG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTDPTSIKHQTTLTSGTSADFTQAGEPFALFAEWFAEASKSEPNDPNAMALSTVDADGLPDVRMVLMKGYDADGFVFYSH
KASQKGQELAANPKAALLFHWKSLRRQVRIRGLVTPVTDAEADAYFATRPKQAQLGAWASKQSQPLESRFAFEQAIAKVA
TQYIIGEVPRPPGWSGWRITPVRMEFWHDRPFRLHDRIEFRREAAGQPWTKVRMYP

Sequences:

>Translated_216_residues
MTDPTSIKHQTTLTSGTSADFTQAGEPFALFAEWFAEASKSEPNDPNAMALSTVDADGLPDVRMVLMKGYDADGFVFYSH
KASQKGQELAANPKAALLFHWKSLRRQVRIRGLVTPVTDAEADAYFATRPKQAQLGAWASKQSQPLESRFAFEQAIAKVA
TQYIIGEVPRPPGWSGWRITPVRMEFWHDRPFRLHDRIEFRREAAGQPWTKVRMYP
>Mature_215_residues
TDPTSIKHQTTLTSGTSADFTQAGEPFALFAEWFAEASKSEPNDPNAMALSTVDADGLPDVRMVLMKGYDADGFVFYSHK
ASQKGQELAANPKAALLFHWKSLRRQVRIRGLVTPVTDAEADAYFATRPKQAQLGAWASKQSQPLESRFAFEQAIAKVAT
QYIIGEVPRPPGWSGWRITPVRMEFWHDRPFRLHDRIEFRREAAGQPWTKVRMYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=178, Percent_Identity=43.2584269662921, Blast_Score=154, Evalue=5e-38,
Organism=Escherichia coli, GI1787926, Length=191, Percent_Identity=38.2198952879581, Blast_Score=153, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17553712, Length=196, Percent_Identity=37.7551020408163, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319509, Length=196, Percent_Identity=39.2857142857143, Blast_Score=149, Evalue=4e-37,
Organism=Drosophila melanogaster, GI45551845, Length=185, Percent_Identity=40.5405405405405, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24644901, Length=185, Percent_Identity=40.5405405405405, Blast_Score=137, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24644903, Length=167, Percent_Identity=28.7425149700599, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24373; Mature: 24242

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPTSIKHQTTLTSGTSADFTQAGEPFALFAEWFAEASKSEPNDPNAMALSTVDADGLP
CCCCCCCCEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCC
DVRMVLMKGYDADGFVFYSHKASQKGQELAANPKAALLFHWKSLRRQVRIRGLVTPVTDA
HHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCCEEEEHHHHHHHHHHHHHEEECCCCCC
EADAYFATRPKQAQLGAWASKQSQPLESRFAFEQAIAKVATQYIIGEVPRPPGWSGWRIT
CCCCEECCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
PVRMEFWHDRPFRLHDRIEFRREAAGQPWTKVRMYP
EEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure 
TDPTSIKHQTTLTSGTSADFTQAGEPFALFAEWFAEASKSEPNDPNAMALSTVDADGLP
CCCCCCCEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCC
DVRMVLMKGYDADGFVFYSHKASQKGQELAANPKAALLFHWKSLRRQVRIRGLVTPVTDA
HHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCCEEEEHHHHHHHHHHHHHEEECCCCCC
EADAYFATRPKQAQLGAWASKQSQPLESRFAFEQAIAKVATQYIIGEVPRPPGWSGWRIT
CCCCEECCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
PVRMEFWHDRPFRLHDRIEFRREAAGQPWTKVRMYP
EEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA