Click here to switch to the map view.

The map label for this gene is Ena [H]

Identifier: 146339166

GI number: 146339166

Start: 2260124

End: 2261320

Strand: Reverse

Name: Ena [H]

Synonym: BRADO2124

Alternate gene names: 146339166

Gene position: 2261320-2260124 (Counterclockwise)

Preceding gene: 146339170

Following gene: 146339157

Centisome position: 30.33

GC content: 68.0

Gene sequence:

>1197_bases
ATGGCTCATGACGCGCCGCAAGCGACCGGTCCCAGCAAGCTGGTCATCCGCAACATCGGCCTGATGCTGTCCGGAGCGCT
GGAGCGGCCGATCCTGGATGCCGACACGATCGTCGCCGAGAATGGCAAGATCACCGCCATCGGCCGCCTCAAGGACGTCG
ACACCTCGGGCGCGACGACTATTGTCGACGCGCATGGCACGACCGTCGCACCGGGCTTGATCGACAGCCACGTCCACCCC
GTCGCCGGCGACTGGACGCCTCGGCAGAACCAGATCAACTGGATCGACTCCTACCTGCATGGCGGCGTCACCACCATGAT
CTCGGCCGGCGAGGTGCACATGCCCGGCCGTCCGCGCGACGTCGTCGGCTTGAAGGCAATGGCGATCTTCGCGCAGCGCG
CGTTCTGGACGCTGCGCCCCGGCGGGGTGAAGGTTCACGCTGGCGCACCGGTCATCGAATGCGAGATGGTCGAGGACGAT
TTCAAGGAGCTGGCCGCCGCCGGCGTCAAGCTGCTCGGCGAGGTCGGCCTCGGCGGGGTGAAGGACGGCCCGACCGCGCG
CAAGATGGTCGGCTGGGCGCGCAAATACGGCATCCAGAGCACGATCCACACCGGCGGCCCGTCGATCCCCGGCTCCGGCC
TGATCGACAAGGACGTCGTGCTGGAGGCCGGCACCGACGTCGTCGGGCACATCAATGGTGGCCACACCGCCCTGCCCGAC
GACCAGATCCGCTGCATCTGCGAGGGCTGCAAGGCCGGACTCGAACTCGTCCATAACGGCAATGAGCGCTCGGCGCTGTT
CACCCTGCGCACCGCGCGCGAAATGAACGAGCTCAACCGCGTCATCCTTGGCACCGACGCGCCCGCCGGCTCCGGCGTGC
AGCCGCTCGGCATCCTGCGCATGGTGTCGCTGCTGTCCTCGCTCGGCGACGTGCCCGCCGAGATCGCCTTCTGCTTCGCC
ACCGGCAACACCGCGCGGATGCGCGAGCTCGATTGCGGCCTGATCGAGATCGGCCGCTCCGCCGATTTCGTGATCATGGA
CAAGGCGCAGCACTCGCCGGCCAAGACGCTGCTCGACAGCGTCCAGCTCGGCGACCTCCCCGGCATCGGCATGACCATCA
TCGACGGCGTCGTCCGCACCCAGCGCAGCCGCAATACGCCGCCCGCGACGAAGATCCCGGAGATCGTGGCAAAGTAG

Upstream 100 bases:

>100_bases
GCCCGAACGATTCATTCGTGTACGAATGACCACAACCGGCTTGATGCTGCGCCGCGTGGAGGCGCAAACTGCCGCAGAAC
GCTCAGAAGAAGGACATCCG

Downstream 100 bases:

>100_bases
GTCGCCGATCGCTGCGCCGTCTTTGTGGGCGCGGCGGTGAGCGTTCCTAGCTCGCTCAACACCAACGGTGTCGTCCCGGC
CTCGAGCCGGGACCCATACT

Product: putative aminohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAHDAPQATGPSKLVIRNIGLMLSGALERPILDADTIVAENGKITAIGRLKDVDTSGATTIVDAHGTTVAPGLIDSHVHP
VAGDWTPRQNQINWIDSYLHGGVTTMISAGEVHMPGRPRDVVGLKAMAIFAQRAFWTLRPGGVKVHAGAPVIECEMVEDD
FKELAAAGVKLLGEVGLGGVKDGPTARKMVGWARKYGIQSTIHTGGPSIPGSGLIDKDVVLEAGTDVVGHINGGHTALPD
DQIRCICEGCKAGLELVHNGNERSALFTLRTAREMNELNRVILGTDAPAGSGVQPLGILRMVSLLSSLGDVPAEIAFCFA
TGNTARMRELDCGLIEIGRSADFVIMDKAQHSPAKTLLDSVQLGDLPGIGMTIIDGVVRTQRSRNTPPATKIPEIVAK

Sequences:

>Translated_398_residues
MAHDAPQATGPSKLVIRNIGLMLSGALERPILDADTIVAENGKITAIGRLKDVDTSGATTIVDAHGTTVAPGLIDSHVHP
VAGDWTPRQNQINWIDSYLHGGVTTMISAGEVHMPGRPRDVVGLKAMAIFAQRAFWTLRPGGVKVHAGAPVIECEMVEDD
FKELAAAGVKLLGEVGLGGVKDGPTARKMVGWARKYGIQSTIHTGGPSIPGSGLIDKDVVLEAGTDVVGHINGGHTALPD
DQIRCICEGCKAGLELVHNGNERSALFTLRTAREMNELNRVILGTDAPAGSGVQPLGILRMVSLLSSLGDVPAEIAFCFA
TGNTARMRELDCGLIEIGRSADFVIMDKAQHSPAKTLLDSVQLGDLPGIGMTIIDGVVRTQRSRNTPPATKIPEIVAK
>Mature_397_residues
AHDAPQATGPSKLVIRNIGLMLSGALERPILDADTIVAENGKITAIGRLKDVDTSGATTIVDAHGTTVAPGLIDSHVHPV
AGDWTPRQNQINWIDSYLHGGVTTMISAGEVHMPGRPRDVVGLKAMAIFAQRAFWTLRPGGVKVHAGAPVIECEMVEDDF
KELAAAGVKLLGEVGLGGVKDGPTARKMVGWARKYGIQSTIHTGGPSIPGSGLIDKDVVLEAGTDVVGHINGGHTALPDD
QIRCICEGCKAGLELVHNGNERSALFTLRTAREMNELNRVILGTDAPAGSGVQPLGILRMVSLLSSLGDVPAEIAFCFAT
GNTARMRELDCGLIEIGRSADFVIMDKAQHSPAKTLLDSVQLGDLPGIGMTIIDGVVRTQRSRNTPPATKIPEIVAK

Specific function: Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.18 [H]

Molecular weight: Translated: 41870; Mature: 41739

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHDAPQATGPSKLVIRNIGLMLSGALERPILDADTIVAENGKITAIGRLKDVDTSGATT
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEECEEECCCCCCEE
IVDAHGTTVAPGLIDSHVHPVAGDWTPRQNQINWIDSYLHGGVTTMISAGEVHMPGRPRD
EEECCCCEECCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHEEEECCEEECCCCCCH
VVGLKAMAIFAQRAFWTLRPGGVKVHAGAPVIECEMVEDDFKELAAAGVKLLGEVGLGGV
HHHHHHHHHHHHHHEEEECCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCC
KDGPTARKMVGWARKYGIQSTIHTGGPSIPGSGLIDKDVVLEAGTDVVGHINGGHTALPD
CCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCC
DQIRCICEGCKAGLELVHNGNERSALFTLRTAREMNELNRVILGTDAPAGSGVQPLGILR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHCCEEEEECCCCCCCCCCHHHHHH
MVSLLSSLGDVPAEIAFCFATGNTARMRELDCGLIEIGRSADFVIMDKAQHSPAKTLLDS
HHHHHHHHCCCCCEEEEEEECCCCHHHHHCCCCCEEECCCCCEEEEECCCCCHHHHHHHH
VQLGDLPGIGMTIIDGVVRTQRSRNTPPATKIPEIVAK
HHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCC
>Mature Secondary Structure 
AHDAPQATGPSKLVIRNIGLMLSGALERPILDADTIVAENGKITAIGRLKDVDTSGATT
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEECEEECCCCCCEE
IVDAHGTTVAPGLIDSHVHPVAGDWTPRQNQINWIDSYLHGGVTTMISAGEVHMPGRPRD
EEECCCCEECCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHEEEECCEEECCCCCCH
VVGLKAMAIFAQRAFWTLRPGGVKVHAGAPVIECEMVEDDFKELAAAGVKLLGEVGLGGV
HHHHHHHHHHHHHHEEEECCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCC
KDGPTARKMVGWARKYGIQSTIHTGGPSIPGSGLIDKDVVLEAGTDVVGHINGGHTALPD
CCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCC
DQIRCICEGCKAGLELVHNGNERSALFTLRTAREMNELNRVILGTDAPAGSGVQPLGILR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHCCEEEEECCCCCCCCCCHHHHHH
MVSLLSSLGDVPAEIAFCFATGNTARMRELDCGLIEIGRSADFVIMDKAQHSPAKTLLDS
HHHHHHHHCCCCCEEEEEEECCCCHHHHHCCCCCEEECCCCCEEEEECCCCCHHHHHHHH
VQLGDLPGIGMTIIDGVVRTQRSRNTPPATKIPEIVAK
HHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA