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The map label for this gene is zraS [C]

Identifier: 146339133

GI number: 146339133

Start: 2222223

End: 2223920

Strand: Direct

Name: zraS [C]

Synonym: BRADO2087

Alternate gene names: 146339133

Gene position: 2222223-2223920 (Clockwise)

Preceding gene: 146339132

Following gene: 146339135

Centisome position: 29.8

GC content: 68.73

Gene sequence:

>1698_bases
ATGAGCACTGAGCAGGATCAGCGCGTTCTCCTCTTCGCGCCGATCGGGCGCGATGGTCCGGCCTCCGCGGAGCTGCTACG
GAGCGCGAGGATCGATACGCAGATCTGCTCCGCCCTTACCGAGCTCGTCCATGAGTTGAGCGCGGGCGTCAGCGTGGTCG
TGGTGGCGGAGGAGGGGCTGTTCGCGAGAGACACGGCGCCGCTCACCGAGTGGGTCGAGCGGCAGCCCGCGTGGTCCGAT
CTCCCGTTCATCGTGCTGACAAGCCATCGGGACCAACCCGCGGTCGTCGCCTGGCGCCGCAGCCTGGTGCGCGCGCTGCG
CAACGTGTCGCTGCTGGAACGGCCGATCCAGCCGATCACGCTCCTGAGCGCGGTGCAATCGGCGATGCGGGCCAGGCGTC
GCCAGTATGAAATCCGCGCACTGATTCACGCACGTGAACAGGCCGCGCAGGAGCTCGAGCGACTGGTGGTGGAGCGCACC
CGCGCGCTCGCCGAGTCCAACGAACACCTCCGCCTGGAGATGGCCGAGCGCGCGCGCGTCGAGGAGACCTTGCGTCAGGC
CCAGAAGATCGAGGCCATCGGCCGGCTGACCGGCGGCGTCGCGCATGATTTCAACAATCTGCTGATGGTGATCTCGGGCG
GGCTCGACATGCTGGACCGCCAGGCCGATCCGGCGCGCCGCCGCCGCCTGATGGACGGCATGATCCAGGCGGCGCAGCGT
GGCGCCAGCCTGACCCGCCAGCTGCTCGCCTTTTCCCGCCGGCAGGAGCTGAAGCCCGAGCCGGTCGACATCGCCCGCCA
GATCGGCGGCATGCGCGAGCTGCTCGATCGCAGCCTGCGCGGCGATGTGCACGTGCAGTTCGAGTTTCCGGAGGACCTCT
GGCCGGTCGAGGTCGATCCCGGTGAGCTCGAGCTTGTCGTGCTCAACCTCGCGGTCAACGCGCGGGATGCGATGCCGACC
GGCGGCACCATCGTGGTGCACGGCGAGAACCTGCCGAATTGGCGGGACGATGAGGTCGCAGGCGACTACGTCCGGCTGTC
GGTGATCGACTCCGGGACCGGCATGACGGAGGAGGTCCGGGCACGCGTGTTCGAGCCGTTCTTCACGACCAAGGACATTG
GCAAGGGCTCGGGTCTCGGTCTGGCCCAGGTGTACGGCTTCGCGAAGCAGTCCCGCGGCTCCGTCTGCATCGAGTCCGAG
CTCGGGCGCGGCTCCGCGATTTCGCTCTACCTGCCGCGGTCGGAGCATGCCGCCTCGGGCGTCCAGCCGCACCTCCTCGA
TCTGCAGCGACCGAGATCGCGCCTTCACGACGAGGGGCGCGTTCTTCTGGTCGAGGATGACGACGAGGTTGCGGCGCTGG
TCAGCGAGATGCTGCGCCAGCTCGGTTATGACGTGACCCGCGCCTCGAGCGCCGCCGCGGCGCTCGGCGCGCTCGCCGAC
GGACGTCCGGTCGATCTCGTCTTCTCCGATGTCATGATGCCCGGGGGCATGAACGGGGTCGAGCTCGCGCGCGAGATCCA
GCGGCGGCGGGTCGACATGCCGATCCTGCTCACCAGCGGCTATTCGGGAGCTGCGGTTCACGCCGCCAGGGAAGCGGGCG
TCCGCATCCTGTCAAAGCCTTACCGGATCGACGAGCTGGCGGCGGCGATCGATGCGGCAAAAATGGAGAGCGAATGGAGC
CGCGCGCGCAGCTCCTGA

Upstream 100 bases:

>100_bases
AAGGGAATCACCCTCGGTCCGCCGCTGACCGATTTCAGCGGAATCTTCCTTGGCAATCCGCGCTTCTCCGGCGCCGTGAT
CCCCGATGTGGACAAGCGAG

Downstream 100 bases:

>100_bases
ACCCGCGCGGCCCTCTCATGTGCTGACGTGATGCCGGACGCTTACGATAGCGTCGGCGCCGCCTCGGCGGCGGCATGCTC
GACCGCAGCGGCCGCATCCA

Product: sensor histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MSTEQDQRVLLFAPIGRDGPASAELLRSARIDTQICSALTELVHELSAGVSVVVVAEEGLFARDTAPLTEWVERQPAWSD
LPFIVLTSHRDQPAVVAWRRSLVRALRNVSLLERPIQPITLLSAVQSAMRARRRQYEIRALIHAREQAAQELERLVVERT
RALAESNEHLRLEMAERARVEETLRQAQKIEAIGRLTGGVAHDFNNLLMVISGGLDMLDRQADPARRRRLMDGMIQAAQR
GASLTRQLLAFSRRQELKPEPVDIARQIGGMRELLDRSLRGDVHVQFEFPEDLWPVEVDPGELELVVLNLAVNARDAMPT
GGTIVVHGENLPNWRDDEVAGDYVRLSVIDSGTGMTEEVRARVFEPFFTTKDIGKGSGLGLAQVYGFAKQSRGSVCIESE
LGRGSAISLYLPRSEHAASGVQPHLLDLQRPRSRLHDEGRVLLVEDDDEVAALVSEMLRQLGYDVTRASSAAAALGALAD
GRPVDLVFSDVMMPGGMNGVELAREIQRRRVDMPILLTSGYSGAAVHAAREAGVRILSKPYRIDELAAAIDAAKMESEWS
RARSS

Sequences:

>Translated_565_residues
MSTEQDQRVLLFAPIGRDGPASAELLRSARIDTQICSALTELVHELSAGVSVVVVAEEGLFARDTAPLTEWVERQPAWSD
LPFIVLTSHRDQPAVVAWRRSLVRALRNVSLLERPIQPITLLSAVQSAMRARRRQYEIRALIHAREQAAQELERLVVERT
RALAESNEHLRLEMAERARVEETLRQAQKIEAIGRLTGGVAHDFNNLLMVISGGLDMLDRQADPARRRRLMDGMIQAAQR
GASLTRQLLAFSRRQELKPEPVDIARQIGGMRELLDRSLRGDVHVQFEFPEDLWPVEVDPGELELVVLNLAVNARDAMPT
GGTIVVHGENLPNWRDDEVAGDYVRLSVIDSGTGMTEEVRARVFEPFFTTKDIGKGSGLGLAQVYGFAKQSRGSVCIESE
LGRGSAISLYLPRSEHAASGVQPHLLDLQRPRSRLHDEGRVLLVEDDDEVAALVSEMLRQLGYDVTRASSAAAALGALAD
GRPVDLVFSDVMMPGGMNGVELAREIQRRRVDMPILLTSGYSGAAVHAAREAGVRILSKPYRIDELAAAIDAAKMESEWS
RARSS
>Mature_564_residues
STEQDQRVLLFAPIGRDGPASAELLRSARIDTQICSALTELVHELSAGVSVVVVAEEGLFARDTAPLTEWVERQPAWSDL
PFIVLTSHRDQPAVVAWRRSLVRALRNVSLLERPIQPITLLSAVQSAMRARRRQYEIRALIHAREQAAQELERLVVERTR
ALAESNEHLRLEMAERARVEETLRQAQKIEAIGRLTGGVAHDFNNLLMVISGGLDMLDRQADPARRRRLMDGMIQAAQRG
ASLTRQLLAFSRRQELKPEPVDIARQIGGMRELLDRSLRGDVHVQFEFPEDLWPVEVDPGELELVVLNLAVNARDAMPTG
GTIVVHGENLPNWRDDEVAGDYVRLSVIDSGTGMTEEVRARVFEPFFTTKDIGKGSGLGLAQVYGFAKQSRGSVCIESEL
GRGSAISLYLPRSEHAASGVQPHLLDLQRPRSRLHDEGRVLLVEDDDEVAALVSEMLRQLGYDVTRASSAAAALGALADG
RPVDLVFSDVMMPGGMNGVELAREIQRRRVDMPILLTSGYSGAAVHAAREAGVRILSKPYRIDELAAAIDAAKMESEWSR
ARSS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=30.1255230125523, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=26.9709543568465, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=312, Percent_Identity=28.525641025641, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=28.2945736434109, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=272, Percent_Identity=27.5735294117647, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790861, Length=261, Percent_Identity=26.8199233716475, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790299, Length=117, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=28.0334728033473, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62399; Mature: 62268

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00260 GLUCAGON

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEQDQRVLLFAPIGRDGPASAELLRSARIDTQICSALTELVHELSAGVSVVVVAEEGL
CCCCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
FARDTAPLTEWVERQPAWSDLPFIVLTSHRDQPAVVAWRRSLVRALRNVSLLERPIQPIT
CCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
LLSAVQSAMRARRRQYEIRALIHAREQAAQELERLVVERTRALAESNEHLRLEMAERARV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
EETLRQAQKIEAIGRLTGGVAHDFNNLLMVISGGLDMLDRQADPARRRRLMDGMIQAAQR
HHHHHHHHHHHHHHHHHCHHHHHHHCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHH
GASLTRQLLAFSRRQELKPEPVDIARQIGGMRELLDRSLRGDVHVQFEFPEDLWPVEVDP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCCCEECCC
GELELVVLNLAVNARDAMPTGGTIVVHGENLPNWRDDEVAGDYVRLSVIDSGTGMTEEVR
CCEEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHH
ARVFEPFFTTKDIGKGSGLGLAQVYGFAKQSRGSVCIESELGRGSAISLYLPRSEHAASG
HHHHCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCHHHCCC
VQPHLLDLQRPRSRLHDEGRVLLVEDDDEVAALVSEMLRQLGYDVTRASSAAAALGALAD
CCCHHHHHHCHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
GRPVDLVFSDVMMPGGMNGVELAREIQRRRVDMPILLTSGYSGAAVHAAREAGVRILSKP
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCHHHHCCC
YRIDELAAAIDAAKMESEWSRARSS
CCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STEQDQRVLLFAPIGRDGPASAELLRSARIDTQICSALTELVHELSAGVSVVVVAEEGL
CCCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
FARDTAPLTEWVERQPAWSDLPFIVLTSHRDQPAVVAWRRSLVRALRNVSLLERPIQPIT
CCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
LLSAVQSAMRARRRQYEIRALIHAREQAAQELERLVVERTRALAESNEHLRLEMAERARV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
EETLRQAQKIEAIGRLTGGVAHDFNNLLMVISGGLDMLDRQADPARRRRLMDGMIQAAQR
HHHHHHHHHHHHHHHHHCHHHHHHHCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHH
GASLTRQLLAFSRRQELKPEPVDIARQIGGMRELLDRSLRGDVHVQFEFPEDLWPVEVDP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCCCEECCC
GELELVVLNLAVNARDAMPTGGTIVVHGENLPNWRDDEVAGDYVRLSVIDSGTGMTEEVR
CCEEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHH
ARVFEPFFTTKDIGKGSGLGLAQVYGFAKQSRGSVCIESELGRGSAISLYLPRSEHAASG
HHHHCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCHHHCCC
VQPHLLDLQRPRSRLHDEGRVLLVEDDDEVAALVSEMLRQLGYDVTRASSAAAALGALAD
CCCHHHHHHCHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
GRPVDLVFSDVMMPGGMNGVELAREIQRRRVDMPILLTSGYSGAAVHAAREAGVRILSKP
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCHHHHCCC
YRIDELAAAIDAAKMESEWSRARSS
CCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA