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The map label for this gene is ywlC [H]

Identifier: 146339104

GI number: 146339104

Start: 2192273

End: 2193274

Strand: Reverse

Name: ywlC [H]

Synonym: BRADO2058

Alternate gene names: 146339104

Gene position: 2193274-2192273 (Counterclockwise)

Preceding gene: 146339108

Following gene: 146339103

Centisome position: 29.41

GC content: 72.26

Gene sequence:

>1002_bases
ATGCCCGCGCCAGACATGCCCGCGATCGAGACCCGAATCCTGCCTGCTGCTGCGGCCGGCATCGCGCAAGCCGCGGCGAT
GTTCGCGCGCGGCGGGCTGGTCGCGTTTCCGACCGAGACCGTCTACGGCCTCGGCGCCGACGCCGCCAATGCGGCGGCGA
TCGCGCACCTCTATCAGGCCAAGGGCCGCCCGGCGTTCAATCCGCTGATCGCTCATGTCGCCGACGCAGCGGCGGCGCGG
CGGATCGGCCGCTTCGATGCCACGGCGGAGCGCCTGGCCGCCGCCTTCTGGCCGGGACCGCTGACCCTCGTGGTGCCGCA
GGCCGATCAGTGCCCCGTTGCGGATCTCGCCACCGCCGGCCTCGACACCGTCGCGATCCGCGTGCCGGCGCATCCGACCG
CGCGGGCGCTGCTCGCCGCGTTCGGCGGCGCGGTCGTCGCGCCCTCGGCCAACATCTCCGGCCATGTGTCGCCGACCACG
GCAGCGCATGTCGCCGCGGATCTCAGTGGGCGCATCGATCTGATCCTGGATGGCGGCGCCGTCGATGTCGGTGTGGAATC
GACCATTATAGGCTGCTTCGCAGAGCCTACCTTGCTGCGCCCAGGCGGAGTTCCCAGCGAGGCGATCGAGGCGGTGCTCG
GCCAGCCGCTCGCCCGCCTCGCCGTAGCCGAGGCACATGCCGCGGAGCAGCCGCTCGCGCCGGGCATGCTGGCCTCGCAT
TATGCGCCGCACGCCGCCGTCCGCCTCGATGCCACCAATGTCGCGCCGGATGAGGCGCTGCTCGCCTTCGGTCCTGTGAC
GTTGCCGGGCGCCGCGCAGGCCGCCGCGATCCTCAACCTGTCGCCCGTCGGCGATCCGGCAGAGGCGGCGACGCATCTTT
TCGGCTATCTTCGCAGCCTCGATGCGAGCGGCGCGCGCAGCATCGCCGTGATGCCGATTCCCAACGATGGCCTCGGCGAG
GCCATCAACGACCGGCTGCGCCGTGCCGCCGCGCCGCGATAA

Upstream 100 bases:

>100_bases
CCAGAGCCGGTCGCAGCCCAGCGGCGCATTTGCGCGCTTCATTCGGGCGTCCCCGCCCGCTATAGCCGAGCGCGACCGCT
CTCCTCGTGCCGTACCCGTC

Downstream 100 bases:

>100_bases
CATTGGAAGCGACCGACCATGAACATCAGCCAGCCTGCCTTCCCGCCGCTGCCCCCCGAGCTGATCGCGCAGTTCGCCGC
CATCGTCGGCGAGCGCCAGG

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MPAPDMPAIETRILPAAAAGIAQAAAMFARGGLVAFPTETVYGLGADAANAAAIAHLYQAKGRPAFNPLIAHVADAAAAR
RIGRFDATAERLAAAFWPGPLTLVVPQADQCPVADLATAGLDTVAIRVPAHPTARALLAAFGGAVVAPSANISGHVSPTT
AAHVAADLSGRIDLILDGGAVDVGVESTIIGCFAEPTLLRPGGVPSEAIEAVLGQPLARLAVAEAHAAEQPLAPGMLASH
YAPHAAVRLDATNVAPDEALLAFGPVTLPGAAQAAAILNLSPVGDPAEAATHLFGYLRSLDASGARSIAVMPIPNDGLGE
AINDRLRRAAAPR

Sequences:

>Translated_333_residues
MPAPDMPAIETRILPAAAAGIAQAAAMFARGGLVAFPTETVYGLGADAANAAAIAHLYQAKGRPAFNPLIAHVADAAAAR
RIGRFDATAERLAAAFWPGPLTLVVPQADQCPVADLATAGLDTVAIRVPAHPTARALLAAFGGAVVAPSANISGHVSPTT
AAHVAADLSGRIDLILDGGAVDVGVESTIIGCFAEPTLLRPGGVPSEAIEAVLGQPLARLAVAEAHAAEQPLAPGMLASH
YAPHAAVRLDATNVAPDEALLAFGPVTLPGAAQAAAILNLSPVGDPAEAATHLFGYLRSLDASGARSIAVMPIPNDGLGE
AINDRLRRAAAPR
>Mature_332_residues
PAPDMPAIETRILPAAAAGIAQAAAMFARGGLVAFPTETVYGLGADAANAAAIAHLYQAKGRPAFNPLIAHVADAAAARR
IGRFDATAERLAAAFWPGPLTLVVPQADQCPVADLATAGLDTVAIRVPAHPTARALLAAFGGAVVAPSANISGHVSPTTA
AHVAADLSGRIDLILDGGAVDVGVESTIIGCFAEPTLLRPGGVPSEAIEAVLGQPLARLAVAEAHAAEQPLAPGMLASHY
APHAAVRLDATNVAPDEALLAFGPVTLPGAAQAAAILNLSPVGDPAEAATHLFGYLRSLDASGARSIAVMPIPNDGLGEA
INDRLRRAAAPR

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=137, Percent_Identity=34.3065693430657, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=217, Percent_Identity=31.3364055299539, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321269, Length=375, Percent_Identity=34.9333333333333, Blast_Score=173, Evalue=4e-44,
Organism=Drosophila melanogaster, GI78707274, Length=146, Percent_Identity=35.6164383561644, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 33398; Mature: 33267

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPDMPAIETRILPAAAAGIAQAAAMFARGGLVAFPTETVYGLGADAANAAAIAHLYQA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHEECCCCHHHHHHHHHHHHH
KGRPAFNPLIAHVADAAAARRIGRFDATAERLAAAFWPGPLTLVVPQADQCPVADLATAG
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHCC
LDTVAIRVPAHPTARALLAAFGGAVVAPSANISGHVSPTTAAHVAADLSGRIDLILDGGA
CCEEEEEECCCHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCE
VDVGVESTIIGCFAEPTLLRPGGVPSEAIEAVLGQPLARLAVAEAHAAEQPLAPGMLASH
EECCCCHHEEEEECCCCEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHH
YAPHAAVRLDATNVAPDEALLAFGPVTLPGAAQAAAILNLSPVGDPAEAATHLFGYLRSL
CCCCEEEEEECCCCCCCCCEEEECCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHC
DASGARSIAVMPIPNDGLGEAINDRLRRAAAPR
CCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PAPDMPAIETRILPAAAAGIAQAAAMFARGGLVAFPTETVYGLGADAANAAAIAHLYQA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHEECCCCHHHHHHHHHHHHH
KGRPAFNPLIAHVADAAAARRIGRFDATAERLAAAFWPGPLTLVVPQADQCPVADLATAG
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHCC
LDTVAIRVPAHPTARALLAAFGGAVVAPSANISGHVSPTTAAHVAADLSGRIDLILDGGA
CCEEEEEECCCHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCE
VDVGVESTIIGCFAEPTLLRPGGVPSEAIEAVLGQPLARLAVAEAHAAEQPLAPGMLASH
EECCCCHHEEEEECCCCEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHH
YAPHAAVRLDATNVAPDEALLAFGPVTLPGAAQAAAILNLSPVGDPAEAATHLFGYLRSL
CCCCEEEEEECCCCCCCCCEEEECCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHC
DASGARSIAVMPIPNDGLGEAINDRLRRAAAPR
CCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]