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The map label for this gene is cheB [H]

Identifier: 146338888

GI number: 146338888

Start: 1954334

End: 1955392

Strand: Direct

Name: cheB [H]

Synonym: BRADO1827

Alternate gene names: 146338888

Gene position: 1954334-1955392 (Clockwise)

Preceding gene: 146338887

Following gene: 146338889

Centisome position: 26.21

GC content: 66.57

Gene sequence:

>1059_bases
ATGAGTGCCATTCGCGTTCTGATCGTCGACGACTCGGCCTTCGTGCGCCAGGTCCTGACCGACATTTTGTCGAGCGACCC
GGCGATCCAGGTCGTCGGCGCCGCGCCGAATCCCATCGTCGCGCGCGACATGATCAAGAGTCTCAACCCCGACGTGCTCA
CGCTCGACATCGAGATGCCGCGCATGGATGGTCTTGCCTTTCTCGACAAGATCATGGCGCTGCGGCCGATGCCGGTCCTG
ATGATCTCGTCGCTCACCCAGAAGGGCGCGGACACTGCCATCCGCGCCCTGGAGATGGGCGCGTTCGATTGCGTGGCGAA
GCCGGTAGTCGGGCTGGTTGAGGGCCTGCCTGCGATGCGCAACGAGATCGTCAGCAAGGTCAAGGCGGCATCGGTCGCGA
AGATCCGGACGCGCTCCGGGGAGCAGGTCCGTCCGATCCAGCGGCCGGGCGTCTCCTACAATACGTCGGAGAAGATCATT
GCGATCGGTGCCTCCACCGGCGGCGTCGAGGCGCTGCAGGAGCTGCTGATGGCGTTTCCCTCCGACGCACCGGCAGCCGT
CATCACCCAGCACATGCCGGCGATGTTCACCGCCTCCTTTGCCGCCCGGCTGAACCAGCTGTGCGCGGTCACGGTCAAAC
AGGCGGTCAGCGGTGAGCGCGTGCTGCCCGGTCACGCCTATATCGCGCCGGGCGGCTTCCACATGGAGCTCGGACGCAAT
GGTGCGAATTATGTCTGCCGCGTCCATGACGAGCCGGCCGTCTCCGGTCATCGGCCGTCAGTCGACGTTCTCTTCAGGTC
CGTCGCGCATGCCGCGGGGCCGAATGCGATCGGCGTCATCCTGACCGGCATGGGACGCGACGGTGCGGTCGGCCTCCTGG
AGATGCGCACGGCGGGAGCGCCGACGATCGGCCAGGACGAGGCGAGCTGCGTCGTCTACGGCATGCCCAAGGCGGCGCGC
GAATGCGGCGCCGTCGAGATCGAGCTGCCGCTCGGCAAGATCGCCGATCAGGTCCTGAAGCGGTGTGAGTCGCTCGCTGC
GCGCGGGGTCAGGGTTTAA

Upstream 100 bases:

>100_bases
GCCGACCACGAGGCGCTGGTCCGCCACGAGACATCCTACAAATCCAAGATCCAGGTCGAGCCCGTCGCCGGATCGATCGA
GCTCTTTTGAGGCAGTACAT

Downstream 100 bases:

>100_bases
TCCATGTTCGGTTGGAAGCAGAGCAGCGCGGCCGAGGCAAGGCCGCCGACCCCAGAGCCGCCAGCGGAGTCCGTCCCTGA
TGCCCGGTCCAAGCAGGACG

Product: chemotaxis response regulator protein CheB-glutamate methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSAIRVLIVDDSAFVRQVLTDILSSDPAIQVVGAAPNPIVARDMIKSLNPDVLTLDIEMPRMDGLAFLDKIMALRPMPVL
MISSLTQKGADTAIRALEMGAFDCVAKPVVGLVEGLPAMRNEIVSKVKAASVAKIRTRSGEQVRPIQRPGVSYNTSEKII
AIGASTGGVEALQELLMAFPSDAPAAVITQHMPAMFTASFAARLNQLCAVTVKQAVSGERVLPGHAYIAPGGFHMELGRN
GANYVCRVHDEPAVSGHRPSVDVLFRSVAHAAGPNAIGVILTGMGRDGAVGLLEMRTAGAPTIGQDEASCVVYGMPKAAR
ECGAVEIELPLGKIADQVLKRCESLAARGVRV

Sequences:

>Translated_352_residues
MSAIRVLIVDDSAFVRQVLTDILSSDPAIQVVGAAPNPIVARDMIKSLNPDVLTLDIEMPRMDGLAFLDKIMALRPMPVL
MISSLTQKGADTAIRALEMGAFDCVAKPVVGLVEGLPAMRNEIVSKVKAASVAKIRTRSGEQVRPIQRPGVSYNTSEKII
AIGASTGGVEALQELLMAFPSDAPAAVITQHMPAMFTASFAARLNQLCAVTVKQAVSGERVLPGHAYIAPGGFHMELGRN
GANYVCRVHDEPAVSGHRPSVDVLFRSVAHAAGPNAIGVILTGMGRDGAVGLLEMRTAGAPTIGQDEASCVVYGMPKAAR
ECGAVEIELPLGKIADQVLKRCESLAARGVRV
>Mature_351_residues
SAIRVLIVDDSAFVRQVLTDILSSDPAIQVVGAAPNPIVARDMIKSLNPDVLTLDIEMPRMDGLAFLDKIMALRPMPVLM
ISSLTQKGADTAIRALEMGAFDCVAKPVVGLVEGLPAMRNEIVSKVKAASVAKIRTRSGEQVRPIQRPGVSYNTSEKIIA
IGASTGGVEALQELLMAFPSDAPAAVITQHMPAMFTASFAARLNQLCAVTVKQAVSGERVLPGHAYIAPGGFHMELGRNG
ANYVCRVHDEPAVSGHRPSVDVLFRSVAHAAGPNAIGVILTGMGRDGAVGLLEMRTAGAPTIGQDEASCVVYGMPKAARE
CGAVEIELPLGKIADQVLKRCESLAARGVRV

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=356, Percent_Identity=55.6179775280899, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI87082052, Length=122, Percent_Identity=35.2459016393443, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 37048; Mature: 36917

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIRVLIVDDSAFVRQVLTDILSSDPAIQVVGAAPNPIVARDMIKSLNPDVLTLDIEMP
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECC
RMDGLAFLDKIMALRPMPVLMISSLTQKGADTAIRALEMGAFDCVAKPVVGLVEGLPAMR
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHH
NEIVSKVKAASVAKIRTRSGEQVRPIQRPGVSYNTSEKIIAIGASTGGVEALQELLMAFP
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCC
SDAPAAVITQHMPAMFTASFAARLNQLCAVTVKQAVSGERVLPGHAYIAPGGFHMELGRN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCCEEEEECCC
GANYVCRVHDEPAVSGHRPSVDVLFRSVAHAAGPNAIGVILTGMGRDGAVGLLEMRTAGA
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEECCCC
PTIGQDEASCVVYGMPKAARECGAVEIELPLGKIADQVLKRCESLAARGVRV
CCCCCCCCCEEEEECCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SAIRVLIVDDSAFVRQVLTDILSSDPAIQVVGAAPNPIVARDMIKSLNPDVLTLDIEMP
CCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECC
RMDGLAFLDKIMALRPMPVLMISSLTQKGADTAIRALEMGAFDCVAKPVVGLVEGLPAMR
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHH
NEIVSKVKAASVAKIRTRSGEQVRPIQRPGVSYNTSEKIIAIGASTGGVEALQELLMAFP
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCC
SDAPAAVITQHMPAMFTASFAARLNQLCAVTVKQAVSGERVLPGHAYIAPGGFHMELGRN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCCEEEEECCC
GANYVCRVHDEPAVSGHRPSVDVLFRSVAHAAGPNAIGVILTGMGRDGAVGLLEMRTAGA
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEECCCC
PTIGQDEASCVVYGMPKAARECGAVEIELPLGKIADQVLKRCESLAARGVRV
CCCCCCCCCEEEEECCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA