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The map label for this gene is dgoR [H]

Identifier: 146338872

GI number: 146338872

Start: 1936162

End: 1936905

Strand: Direct

Name: dgoR [H]

Synonym: BRADO1811

Alternate gene names: 146338872

Gene position: 1936162-1936905 (Clockwise)

Preceding gene: 146338871

Following gene: 146338873

Centisome position: 25.97

GC content: 68.28

Gene sequence:

>744_bases
ATGACGTCGCCGCATATCGTCTCGATTCCGACCCGACGCGCCCATTCCAACCACGCCGAGGTCGCCCGCAGCATCGGTAT
CGACATCATCTCGGGCCGCCTCGGCGAGGGGGCGCGTCTGCCGGGCGATGCCGAGCTGACGGCGACGTTCGGCGTCTCCA
GGCCGGTGCTGCGTGAGAGCGTGAAGACGCTGGTCGCGAAGGGGCTGCTTTCAACCAAGGCGCGCGTCGGCACCGTGGTG
CGCGAGCGCGCGGCCTGGAACATGTTCGATCCGGACGTGCTGGCGTGGCATCTCGACGCGGGAATCGACAAGCGCTTCCT
CGCGGACCTTGCGGAGATCCGGCTGGCCATCGAGCCGCGCGCCGCCGCGCTGGCGGCTGAACGGCGCAGCGAGGACGACA
TTGCCGCGATGCGCAAGGCGATGGCGCAGATGGAGCGCGAGCCGTCGACCTCGGTGGCCTTTGCTGAAGCCGATCTGGCG
CTGCACATCGCGGTCGCCAACGCCTCCGGCAATCCCTTCATGCGCTCGATCGGCGCGGTCATCGAGGCCGCGCTGCGCGC
CTCCTTCGTGCTCAGCGCGCCGGTCGAGATCGCCGATCGCGACACCGTTCTGGTCTGGCACCAGCGCATCATCGATGCGA
TCGCCGACGGCAATCCCGAGGGCGCCTCGGAAGCCATGATCGAAGTCATCTATAACGGCCGGCGGCGTCATGCGCAGTCG
GCTGCACGAACGGACCAGGAATGA

Upstream 100 bases:

>100_bases
TCATTGCGCTGCAGCAAGGTCTGATGGCGCTCGCGCGCCGCTCGTCGCTTAAACCGGCAGGGACCAGGCTTGCGGAGGCC
AGGCCGGCCGGGGCGCCGAC

Downstream 100 bases:

>100_bases
GCAACGACAAGTCAGACAAGCAGCTGCGCAGCCAGGCGTGGTTCGGCCGCCAGGACAAGATGGGCTTCTATTATCGCTCG
TTCCTCAAGAACAGCGGCAC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTSPHIVSIPTRRAHSNHAEVARSIGIDIISGRLGEGARLPGDAELTATFGVSRPVLRESVKTLVAKGLLSTKARVGTVV
RERAAWNMFDPDVLAWHLDAGIDKRFLADLAEIRLAIEPRAAALAAERRSEDDIAAMRKAMAQMEREPSTSVAFAEADLA
LHIAVANASGNPFMRSIGAVIEAALRASFVLSAPVEIADRDTVLVWHQRIIDAIADGNPEGASEAMIEVIYNGRRRHAQS
AARTDQE

Sequences:

>Translated_247_residues
MTSPHIVSIPTRRAHSNHAEVARSIGIDIISGRLGEGARLPGDAELTATFGVSRPVLRESVKTLVAKGLLSTKARVGTVV
RERAAWNMFDPDVLAWHLDAGIDKRFLADLAEIRLAIEPRAAALAAERRSEDDIAAMRKAMAQMEREPSTSVAFAEADLA
LHIAVANASGNPFMRSIGAVIEAALRASFVLSAPVEIADRDTVLVWHQRIIDAIADGNPEGASEAMIEVIYNGRRRHAQS
AARTDQE
>Mature_246_residues
TSPHIVSIPTRRAHSNHAEVARSIGIDIISGRLGEGARLPGDAELTATFGVSRPVLRESVKTLVAKGLLSTKARVGTVVR
ERAAWNMFDPDVLAWHLDAGIDKRFLADLAEIRLAIEPRAAALAAERRSEDDIAAMRKAMAQMEREPSTSVAFAEADLAL
HIAVANASGNPFMRSIGAVIEAALRASFVLSAPVEIADRDTVLVWHQRIIDAIADGNPEGASEAMIEVIYNGRRRHAQSA
ARTDQE

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=213, Percent_Identity=32.8638497652582, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI48994961, Length=207, Percent_Identity=30.4347826086957, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786303, Length=218, Percent_Identity=31.651376146789, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790032, Length=239, Percent_Identity=30.1255230125523, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789621, Length=200, Percent_Identity=28.5, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26655; Mature: 26523

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPHIVSIPTRRAHSNHAEVARSIGIDIISGRLGEGARLPGDAELTATFGVSRPVLRES
CCCCCEEECCCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCCCCCEEEECCCCCHHHHHH
VKTLVAKGLLSTKARVGTVVRERAAWNMFDPDVLAWHLDAGIDKRFLADLAEIRLAIEPR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCH
AAALAAERRSEDDIAAMRKAMAQMEREPSTSVAFAEADLALHIAVANASGNPFMRSIGAV
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEEECCCCCHHHHHHHHH
IEAALRASFVLSAPVEIADRDTVLVWHQRIIDAIADGNPEGASEAMIEVIYNGRRRHAQS
HHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHH
AARTDQE
HHCCCCC
>Mature Secondary Structure 
TSPHIVSIPTRRAHSNHAEVARSIGIDIISGRLGEGARLPGDAELTATFGVSRPVLRES
CCCCEEECCCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCCCCCEEEECCCCCHHHHHH
VKTLVAKGLLSTKARVGTVVRERAAWNMFDPDVLAWHLDAGIDKRFLADLAEIRLAIEPR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCH
AAALAAERRSEDDIAAMRKAMAQMEREPSTSVAFAEADLALHIAVANASGNPFMRSIGAV
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEEECCCCCHHHHHHHHH
IEAALRASFVLSAPVEIADRDTVLVWHQRIIDAIADGNPEGASEAMIEVIYNGRRRHAQS
HHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHH
AARTDQE
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]