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The map label for this gene is hutI

Identifier: 146338671

GI number: 146338671

Start: 1714583

End: 1715797

Strand: Direct

Name: hutI

Synonym: BRADO1603

Alternate gene names: 146338671

Gene position: 1714583-1715797 (Clockwise)

Preceding gene: 146338665

Following gene: 146338672

Centisome position: 22.99

GC content: 67.41

Gene sequence:

>1215_bases
ATGGCCCAGCGTTTCGACCGGATCTGGCAGAATGCGCGGCTCGCGACCTTGGGCGAGGGGCGGCCGGGCCTCGGTGTCAT
CGAGCATGGCGTCGTCGCCTCGCGCGCCGGCCGCATCGCTTTTGCGGGTCCGCAATCGGACTTTGCCGCCGATGCCGATG
CGCCCGAGCGCATCGATTGCGAGGGACGCTGGATCACGCCGGGTCTCATCGATTGCCACACTCATCTCGTCTACGGCGGC
GATCGCGCCCACGAGTTCGAACTGCGCCTCGCCGGCGCGAGCTATGAGGAGATCGCGCGCGCCGGCGGCGGCATCGTGTC
CACGGTAGCGGCGACGCGCGCCGCCAGCGAGGCGGAGCTGATCGCCAGCGCGCTGCCGCGCCTCGATGCGCTGCTCGCCG
AAGGCGTCACCACGATCGAGATCAAGTCCGGCTACGGCCTGGAGACCGCGACCGAACTGCGACAATTGTCTGCAGCGCGT
GCGCTCGGGGAACAACGGCCGGTCAGCGTTCGCACCAGCTTTCTCGGCGCGCATGCGCTGCCGGTCGAAGCCGGCGGCGA
CAAGGAGCGCTATATCGATCTTGTCTGCAACGAGATGCTGCCGGCAGTGGCGCAGTCTGGCGCCGCTGATGCGGTCGATG
CGTTCATGGAGACCATCGCCTTCTCTCCGGAGCAGACTTCGCGCGTTTTCGCGGCGGCCAAGACGCTGGGCCTGCCGGTC
AAGCTGCATGCCGATCAATTGTCCAATCTCGGCGGTGCCGCGCTCGCGGCCGGGTTCGGCGCGCTGTCGGCAGACCATCT
CGAGCACACTGACGAAGTTGGCGCCGTTGCGATGGCGCGGAGCGGGACCGTCGCGGTGCTGTTGCCCGGCGCGTACTACT
TCATCCGCGAGACGCAGAAGCCGCCGGTCGAGCTGTTCCGCAAGCATGGCGTGAAGCTCGCGCTCGCCACCGACTGCAAT
CCCGGGTCATCGCCGCTGACATCCTTGTTGCTGACGATGAACATGGCCGCGACGCTTTTTCGGATGACCGTCGACGAGTG
CATTGCAGGTGTCACGCGCGAAGGCGCCCGCGCGCTCGGCCTGCTCGCTGACACCGGCACGCTCGAACCGGGCAAGTGGT
GCAATCTTGCGATCTGGGATATCGGGCGCCCGGCGGAGCTGGTGTACCGCCTGGGCTTCAATCCCTTGCATCAGCGCGTG
TGGAGAGGCCGATGA

Upstream 100 bases:

>100_bases
CAGTGACGCCATGATCGATCAGCCCGCTGGACAGGACGGCGGAGGTGAGTTTATGTATAGACATATCGCCCGTCAAGCTT
TCGTGAAGGTGGGAGGCCGC

Downstream 100 bases:

>100_bases
ACGCGATCATTGCCGAGCCCGGCCACGTCAGCTTCGATGATCTTGCGCGCGTTTACGCGGGCGCGGCGATTGCCCTTGGT
CCGGCGTATTGGCCGCGGGT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MAQRFDRIWQNARLATLGEGRPGLGVIEHGVVASRAGRIAFAGPQSDFAADADAPERIDCEGRWITPGLIDCHTHLVYGG
DRAHEFELRLAGASYEEIARAGGGIVSTVAATRAASEAELIASALPRLDALLAEGVTTIEIKSGYGLETATELRQLSAAR
ALGEQRPVSVRTSFLGAHALPVEAGGDKERYIDLVCNEMLPAVAQSGAADAVDAFMETIAFSPEQTSRVFAAAKTLGLPV
KLHADQLSNLGGAALAAGFGALSADHLEHTDEVGAVAMARSGTVAVLLPGAYYFIRETQKPPVELFRKHGVKLALATDCN
PGSSPLTSLLLTMNMAATLFRMTVDECIAGVTREGARALGLLADTGTLEPGKWCNLAIWDIGRPAELVYRLGFNPLHQRV
WRGR

Sequences:

>Translated_404_residues
MAQRFDRIWQNARLATLGEGRPGLGVIEHGVVASRAGRIAFAGPQSDFAADADAPERIDCEGRWITPGLIDCHTHLVYGG
DRAHEFELRLAGASYEEIARAGGGIVSTVAATRAASEAELIASALPRLDALLAEGVTTIEIKSGYGLETATELRQLSAAR
ALGEQRPVSVRTSFLGAHALPVEAGGDKERYIDLVCNEMLPAVAQSGAADAVDAFMETIAFSPEQTSRVFAAAKTLGLPV
KLHADQLSNLGGAALAAGFGALSADHLEHTDEVGAVAMARSGTVAVLLPGAYYFIRETQKPPVELFRKHGVKLALATDCN
PGSSPLTSLLLTMNMAATLFRMTVDECIAGVTREGARALGLLADTGTLEPGKWCNLAIWDIGRPAELVYRLGFNPLHQRV
WRGR
>Mature_403_residues
AQRFDRIWQNARLATLGEGRPGLGVIEHGVVASRAGRIAFAGPQSDFAADADAPERIDCEGRWITPGLIDCHTHLVYGGD
RAHEFELRLAGASYEEIARAGGGIVSTVAATRAASEAELIASALPRLDALLAEGVTTIEIKSGYGLETATELRQLSAARA
LGEQRPVSVRTSFLGAHALPVEAGGDKERYIDLVCNEMLPAVAQSGAADAVDAFMETIAFSPEQTSRVFAAAKTLGLPVK
LHADQLSNLGGAALAAGFGALSADHLEHTDEVGAVAMARSGTVAVLLPGAYYFIRETQKPPVELFRKHGVKLALATDCNP
GSSPLTSLLLTMNMAATLFRMTVDECIAGVTREGARALGLLADTGTLEPGKWCNLAIWDIGRPAELVYRLGFNPLHQRVW
RGR

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=371, Percent_Identity=36.6576819407008, Blast_Score=211, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI17555004, Length=353, Percent_Identity=30.5949008498584, Blast_Score=183, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_BRASO (A4YNK6)

Other databases:

- EMBL:   CU234118
- RefSeq:   YP_001203719.1
- ProteinModelPortal:   A4YNK6
- SMR:   A4YNK6
- STRING:   A4YNK6
- GeneID:   5118395
- GenomeReviews:   CU234118_GR
- KEGG:   bra:BRADO1603
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   BSP376:BRADO1603-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 42831; Mature: 42700

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: BINDING 82-82 BINDING 95-95 BINDING 145-145 BINDING 178-178 BINDING 246-246

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRFDRIWQNARLATLGEGRPGLGVIEHGVVASRAGRIAFAGPQSDFAADADAPERIDC
CCHHHHHHHHCCEEEEECCCCCCCCHHHCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCC
EGRWITPGLIDCHTHLVYGGDRAHEFELRLAGASYEEIARAGGGIVSTVAATRAASEAEL
CCCEECCCHHHCCEEEEECCCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
IASALPRLDALLAEGVTTIEIKSGYGLETATELRQLSAARALGEQRPVSVRTSFLGAHAL
HHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
PVEAGGDKERYIDLVCNEMLPAVAQSGAADAVDAFMETIAFSPEQTSRVFAAAKTLGLPV
EECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCE
KLHADQLSNLGGAALAAGFGALSADHLEHTDEVGAVAMARSGTVAVLLPGAYYFIRETQK
EECHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCEEEEECCEEEEEECCCC
PPVELFRKHGVKLALATDCNPGSSPLTSLLLTMNMAATLFRMTVDECIAGVTREGARALG
CHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEE
LLADTGTLEPGKWCNLAIWDIGRPAELVYRLGFNPLHQRVWRGR
EEECCCCCCCCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure 
AQRFDRIWQNARLATLGEGRPGLGVIEHGVVASRAGRIAFAGPQSDFAADADAPERIDC
CHHHHHHHHCCEEEEECCCCCCCCHHHCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCC
EGRWITPGLIDCHTHLVYGGDRAHEFELRLAGASYEEIARAGGGIVSTVAATRAASEAEL
CCCEECCCHHHCCEEEEECCCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
IASALPRLDALLAEGVTTIEIKSGYGLETATELRQLSAARALGEQRPVSVRTSFLGAHAL
HHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
PVEAGGDKERYIDLVCNEMLPAVAQSGAADAVDAFMETIAFSPEQTSRVFAAAKTLGLPV
EECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCE
KLHADQLSNLGGAALAAGFGALSADHLEHTDEVGAVAMARSGTVAVLLPGAYYFIRETQK
EECHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCEEEEECCEEEEEECCCC
PPVELFRKHGVKLALATDCNPGSSPLTSLLLTMNMAATLFRMTVDECIAGVTREGARALG
CHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEE
LLADTGTLEPGKWCNLAIWDIGRPAELVYRLGFNPLHQRVWRGR
EEECCCCCCCCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA