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The map label for this gene is trxB [C]

Identifier: 146338653

GI number: 146338653

Start: 1697886

End: 1698809

Strand: Direct

Name: trxB [C]

Synonym: BRADO1584

Alternate gene names: 146338653

Gene position: 1697886-1698809 (Clockwise)

Preceding gene: 146338651

Following gene: 146338654

Centisome position: 22.77

GC content: 65.26

Gene sequence:

>924_bases
ATGCGCACTGAAGTTCTGGTCATCGGCGGCGGCCCCGCAGGACTGATGGCCGCGATCTATCTTGCGCGATTCAGGCGCCA
TGTCGTTGTCGTCGATAGCGGCGCATCGCGCGCGGCGCTTATCCCGCGCAGCCACAATCTGCCCGGGTTTCCGAACGGCC
TTCCTGGCAGCGAGCTGTTGGCTCGCATGCAGCGGCAGGTCGAGGAGCTTGGCGTGCCGATCATTCGCGGCACGGTCACC
GCGCTGGAAACCCGCGATGATCGAATCCTCGCCGCACACAAAGGAGAGCCGATTGTGGCGCAACGCGCCATGCTGGCGAC
CGGCATCGTCGACAAGCAAACGCCGCTGGTCGATTGGACTGTGGCGGTGCGTGAAGGGGCGCTGCGCTATTGCCCGGTCT
GCGACGCGTTCGAGGCGATCGGCCGCAAGATCGCGATCATCGGTCCGCTTGGACACGCCGCGGGCAAGGCGCTGTTCATG
CGTGTGTATAGTTCCGACGTCACGCTGATCCCGGTCGGAGACGAGCAGAACGACGAGAAGCGGCGGGAGCTCGCCGGGGC
CGGCGTTCGCGTGACGCCGCCGCTGCGCGGGCTGCAACGGGAGGAGGACGTCATGTCGGCCACTTTTGCGGATGGAAGTT
GCGAACGCTTCGAGATCGTCTATCCGGCCATGGGCGCCGATGTTCGTTCCGAGCTCGCGATCGCGCTCGGCGCGCGGCAT
ACGTCCGACGGGTTTCTCGAGGTCGATGGCAAGCAACGCTGCGGCGTCGACCGCCTCTATGGCATTGGCGACGTCGTCAC
CGACCTGCACCAGATCGCGGTGGCGTTCGGCCATGCTGCAGTCGCGGCATGCCACGCACATCATTCGCTTCCGATGCGCT
ATGCGGAACCATCCGGGGCGCAGGACAAATTGATCACAACCTGA

Upstream 100 bases:

>100_bases
CCGTTTGTGTTCCAACCTGTCTTCGCCGGTTGACGCATCAACTCACAGGAACCCTTCCGTCGCTCGACATTTGGTTCCGC
GATCCAAAACGAGGACGGCG

Downstream 100 bases:

>100_bases
AATCGCGATATCCTATGTAAGTGCCGCTGGCGTTGACGTGTCGGACCATGGCGGATGGACAGGAAATCGGCATGTTTGGC
GGCTGCATCCAGCTGCCGTG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRTEVLVIGGGPAGLMAAIYLARFRRHVVVVDSGASRAALIPRSHNLPGFPNGLPGSELLARMQRQVEELGVPIIRGTVT
ALETRDDRILAAHKGEPIVAQRAMLATGIVDKQTPLVDWTVAVREGALRYCPVCDAFEAIGRKIAIIGPLGHAAGKALFM
RVYSSDVTLIPVGDEQNDEKRRELAGAGVRVTPPLRGLQREEDVMSATFADGSCERFEIVYPAMGADVRSELAIALGARH
TSDGFLEVDGKQRCGVDRLYGIGDVVTDLHQIAVAFGHAAVAACHAHHSLPMRYAEPSGAQDKLITT

Sequences:

>Translated_307_residues
MRTEVLVIGGGPAGLMAAIYLARFRRHVVVVDSGASRAALIPRSHNLPGFPNGLPGSELLARMQRQVEELGVPIIRGTVT
ALETRDDRILAAHKGEPIVAQRAMLATGIVDKQTPLVDWTVAVREGALRYCPVCDAFEAIGRKIAIIGPLGHAAGKALFM
RVYSSDVTLIPVGDEQNDEKRRELAGAGVRVTPPLRGLQREEDVMSATFADGSCERFEIVYPAMGADVRSELAIALGARH
TSDGFLEVDGKQRCGVDRLYGIGDVVTDLHQIAVAFGHAAVAACHAHHSLPMRYAEPSGAQDKLITT
>Mature_307_residues
MRTEVLVIGGGPAGLMAAIYLARFRRHVVVVDSGASRAALIPRSHNLPGFPNGLPGSELLARMQRQVEELGVPIIRGTVT
ALETRDDRILAAHKGEPIVAQRAMLATGIVDKQTPLVDWTVAVREGALRYCPVCDAFEAIGRKIAIIGPLGHAAGKALFM
RVYSSDVTLIPVGDEQNDEKRRELAGAGVRVTPPLRGLQREEDVMSATFADGSCERFEIVYPAMGADVRSELAIALGARH
TSDGFLEVDGKQRCGVDRLYGIGDVVTDLHQIAVAFGHAAVAACHAHHSLPMRYAEPSGAQDKLITT

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=172, Percent_Identity=27.906976744186, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320560, Length=183, Percent_Identity=31.1475409836066, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321898, Length=180, Percent_Identity=31.6666666666667, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 32896; Mature: 32896

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTEVLVIGGGPAGLMAAIYLARFRRHVVVVDSGASRAALIPRSHNLPGFPNGLPGSELL
CCEEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCCCCCCCCHHHHH
ARMQRQVEELGVPIIRGTVTALETRDDRILAAHKGEPIVAQRAMLATGIVDKQTPLVDWT
HHHHHHHHHHCCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEE
VAVREGALRYCPVCDAFEAIGRKIAIIGPLGHAAGKALFMRVYSSDVTLIPVGDEQNDEK
EEECCCCEEECCCHHHHHHCCCEEEEEECCCHHHHHHHEEEEECCCEEEEECCCCCCHHH
RRELAGAGVRVTPPLRGLQREEDVMSATFADGSCERFEIVYPAMGADVRSELAIALGARH
HHHHHCCCCEECCCCCCCCHHHHHHHEECCCCCCCEEEEEECCCCCCHHHHHHHHCCCCC
TSDGFLEVDGKQRCGVDRLYGIGDVVTDLHQIAVAFGHAAVAACHAHHSLPMRYAEPSGA
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC
QDKLITT
CCCCCCC
>Mature Secondary Structure
MRTEVLVIGGGPAGLMAAIYLARFRRHVVVVDSGASRAALIPRSHNLPGFPNGLPGSELL
CCEEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCCCCCCCCHHHHH
ARMQRQVEELGVPIIRGTVTALETRDDRILAAHKGEPIVAQRAMLATGIVDKQTPLVDWT
HHHHHHHHHHCCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEE
VAVREGALRYCPVCDAFEAIGRKIAIIGPLGHAAGKALFMRVYSSDVTLIPVGDEQNDEK
EEECCCCEEECCCHHHHHHCCCEEEEEECCCHHHHHHHEEEEECCCEEEEECCCCCCHHH
RRELAGAGVRVTPPLRGLQREEDVMSATFADGSCERFEIVYPAMGADVRSELAIALGARH
HHHHHCCCCEECCCCCCCCHHHHHHHEECCCCCCCEEEEEECCCCCCHHHHHHHHCCCCC
TSDGFLEVDGKQRCGVDRLYGIGDVVTDLHQIAVAFGHAAVAACHAHHSLPMRYAEPSGA
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC
QDKLITT
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]