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The map label for this gene is cobW [H]

Identifier: 146338484

GI number: 146338484

Start: 1498982

End: 1499911

Strand: Direct

Name: cobW [H]

Synonym: BRADO1401

Alternate gene names: 146338484

Gene position: 1498982-1499911 (Clockwise)

Preceding gene: 146338483

Following gene: 146338487

Centisome position: 20.1

GC content: 68.06

Gene sequence:

>930_bases
ATGATCGTCCCGGTCCTGCTGGTCGCAGGCGCGCTCGGCGCCGGCAAGACGACGCTGCTCAATCATCTGCTCGCTTATCC
CGACGGGCGGCGCATCGCCGCCGTCGTCAATGATTTTGGCGCGGTCGATATCGATGCGCAGCTGCTCGGCTCGGTGACGG
AGGAGGTGATCAGCCTGAAGAACGGCTGCATCTGCTGCTCGCTGCAGGGCGATCTGCTGCGCACACTGTCGTCGGTGATC
AAGCGCGACCCCGCGCCGGATGCGATCGCGATCGAGACGTCCGGCATCTCCGATCCGGCCGAGATCATCCGCAACCTGAT
GGATCCTGTGATCTTCAAGGTCGCGCCGCTGGAGACGGTGGTGACGCTGGTCGATCCGCAGCGGCTGCGCGATGATCCCT
CGGTCGCAGACGACGTGCTGTGGCGCTCGCAATTGCGTGCCGCCGACTTCGTGCTGCTGACGAAGTCCGACCTGCTCGAT
CGCGCCGCGCTCGACGAGGCGCGCGCGCTGGTCGGGCGCGTCAAGCCGGCATCCTCGATCTTCGAGATCGCGCGCGGGGT
CGTTGCGCCGGACCTGCTGTTCAGCCGCGACATCAGGGCGCCGCGCACGGCGCCGCGTCAGCTGCCGGTGATGTCCGAGC
CGTTCGCGACCATCACCTGGACGTCCAAGGCGCCGCTGTCGCTGGACCGCTTCCAGCAGGTGATCGGCAAGCTCGCGCCG
CGCACGCTGCGGATCAAGGGCATCCTGCTGTTCACCGAACATCCGGCGCAGCCGATCCTGTTCCAGTCGGTGGCGACGCG
CGGCACCTTGGCGCCGTCGCCGGTGCCGCCGGCCGACGGTCTCACCGCGCAGCTCGTCCTGATCGGGCGCGAGGGAGAGC
TCGATGCGGATCAGATCGACGCGCTGCTGCGCGGCGTGATCATCGACTGA

Upstream 100 bases:

>100_bases
GCGTGCGTCATCTGCTCGTCAATGGCCAGGCTGTGATCACCAACGGTGCGCTGATCCGTGACGCCAGGCCGGGTCGGGCG
GTGCGCCGGCCCGTTTTGTC

Downstream 100 bases:

>100_bases
GACGAAGCGCGGCTCAGCTCGCCTGCCGCAAGGCGCCGCTCTCGGCGTCGACCCAGGTGCAGCCGCCGCCCCCTGCACGC
TTGGCCGCGTAGAGCGCGCT

Product: putative cobalamin synthesis protein cobW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MIVPVLLVAGALGAGKTTLLNHLLAYPDGRRIAAVVNDFGAVDIDAQLLGSVTEEVISLKNGCICCSLQGDLLRTLSSVI
KRDPAPDAIAIETSGISDPAEIIRNLMDPVIFKVAPLETVVTLVDPQRLRDDPSVADDVLWRSQLRAADFVLLTKSDLLD
RAALDEARALVGRVKPASSIFEIARGVVAPDLLFSRDIRAPRTAPRQLPVMSEPFATITWTSKAPLSLDRFQQVIGKLAP
RTLRIKGILLFTEHPAQPILFQSVATRGTLAPSPVPPADGLTAQLVLIGREGELDADQIDALLRGVIID

Sequences:

>Translated_309_residues
MIVPVLLVAGALGAGKTTLLNHLLAYPDGRRIAAVVNDFGAVDIDAQLLGSVTEEVISLKNGCICCSLQGDLLRTLSSVI
KRDPAPDAIAIETSGISDPAEIIRNLMDPVIFKVAPLETVVTLVDPQRLRDDPSVADDVLWRSQLRAADFVLLTKSDLLD
RAALDEARALVGRVKPASSIFEIARGVVAPDLLFSRDIRAPRTAPRQLPVMSEPFATITWTSKAPLSLDRFQQVIGKLAP
RTLRIKGILLFTEHPAQPILFQSVATRGTLAPSPVPPADGLTAQLVLIGREGELDADQIDALLRGVIID
>Mature_309_residues
MIVPVLLVAGALGAGKTTLLNHLLAYPDGRRIAAVVNDFGAVDIDAQLLGSVTEEVISLKNGCICCSLQGDLLRTLSSVI
KRDPAPDAIAIETSGISDPAEIIRNLMDPVIFKVAPLETVVTLVDPQRLRDDPSVADDVLWRSQLRAADFVLLTKSDLLD
RAALDEARALVGRVKPASSIFEIARGVVAPDLLFSRDIRAPRTAPRQLPVMSEPFATITWTSKAPLSLDRFQQVIGKLAP
RTLRIKGILLFTEHPAQPILFQSVATRGTLAPSPVPPADGLTAQLVLIGREGELDADQIDALLRGVIID

Specific function: Might be involved in cobalt reduction leading to cobalt(I) corrinoids [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=337, Percent_Identity=27.299703264095, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI223941779, Length=325, Percent_Identity=26.7692307692308, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI126722884, Length=337, Percent_Identity=27.0029673590504, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI148727351, Length=337, Percent_Identity=27.0029673590504, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI146231952, Length=337, Percent_Identity=27.0029673590504, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI223941776, Length=336, Percent_Identity=27.0833333333333, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI119120938, Length=321, Percent_Identity=25.5451713395639, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI87082430, Length=278, Percent_Identity=30.9352517985612, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788499, Length=152, Percent_Identity=35.5263157894737, Blast_Score=88, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324356, Length=202, Percent_Identity=29.2079207920792, Blast_Score=83, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012824
- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 33173; Mature: 33173

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVPVLLVAGALGAGKTTLLNHLLAYPDGRRIAAVVNDFGAVDIDAQLLGSVTEEVISLK
CHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHHHC
NGCICCSLQGDLLRTLSSVIKRDPAPDAIAIETSGISDPAEIIRNLMDPVIFKVAPLETV
CCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHH
VTLVDPQRLRDDPSVADDVLWRSQLRAADFVLLTKSDLLDRAALDEARALVGRVKPASSI
HHHCCHHHHCCCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHH
FEIARGVVAPDLLFSRDIRAPRTAPRQLPVMSEPFATITWTSKAPLSLDRFQQVIGKLAP
HHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCC
RTLRIKGILLFTEHPAQPILFQSVATRGTLAPSPVPPADGLTAQLVLIGREGELDADQID
CEEEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHH
ALLRGVIID
HHHHHHCCC
>Mature Secondary Structure
MIVPVLLVAGALGAGKTTLLNHLLAYPDGRRIAAVVNDFGAVDIDAQLLGSVTEEVISLK
CHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHHHC
NGCICCSLQGDLLRTLSSVIKRDPAPDAIAIETSGISDPAEIIRNLMDPVIFKVAPLETV
CCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHH
VTLVDPQRLRDDPSVADDVLWRSQLRAADFVLLTKSDLLDRAALDEARALVGRVKPASSI
HHHCCHHHHCCCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHH
FEIARGVVAPDLLFSRDIRAPRTAPRQLPVMSEPFATITWTSKAPLSLDRFQQVIGKLAP
HHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCC
RTLRIKGILLFTEHPAQPILFQSVATRGTLAPSPVPPADGLTAQLVLIGREGELDADQID
CEEEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHH
ALLRGVIID
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]