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The map label for this gene is 146338444

Identifier: 146338444

GI number: 146338444

Start: 1445594

End: 1447822

Strand: Direct

Name: 146338444

Synonym: BRADO1360

Alternate gene names: NA

Gene position: 1445594-1447822 (Clockwise)

Preceding gene: 146338442

Following gene: 146338446

Centisome position: 19.39

GC content: 65.86

Gene sequence:

>2229_bases
GTGACAGAACATGACGATGGCGGCCGATCCCTGGACATTTTCAGCATGCAGCCAGCCTTGCGGAAGCGCGACGATGTCGC
CGACCTGTTCGCCCAGGCGAGCGCGTTTCACCGCTCCGGCGATCTGGCCAAGGCTCAGGCCGGCTACAGGAAGATCCTCA
AGAAGCGGCCAAATCATTTCGGCGCGCTGTATCAGCTTGGACTGTCCGAACACCAGAGCCGCAAGTCCGACGAGGCGGAG
CGCCTGCTGAAGCGGGCGCTGCTGGTCGAGCCGCGGTCCGTCGAGGCGCGGTATGCGCGGGCGGTCGTCCTGTCCGCGCT
GCAGCGGGACAGCGAGGCACTGAGCTGCTTCGACGATCTCCTCGCCTTGAAGCCGGATCTTTTCGACGCGCATCTGGAGC
GCGGCAAGCTGTTGTCGCGTCTCCGGCGTTTCGCCGACGCGGCCGTCAGCTACGACCACGCCATGCTGATCAATCCGCAG
CGGCTGGACGTGTTGATCAACAAGGGCGAAGCGCTGCACTATCTCGGCCGCTTCGTCGATGCGATCGCGTGCTACGACCA
GCTGCTCGCGGCCCATCCCACGCATCTGGCCGCGCTGATCAATCGGGGCTGCGCGTTCAAGGATCTGCGCCGCGCCGACG
AGGCGATCGCCGATTTCGACCGGGCGCTGGCCCTGTCGCCGGACGACACGATTGCGCTGATCAATCGCGGCGAGACGTTC
CTGACGCTGAAACGCAACGCCGACGCGCTCCACGATTTCGACCGCGTGATCGCGCTCGATCCGCAATTTGCGCTGGGCTG
GCTCGGCCGCGCCAATGTCCTGATGTTGAACAAGCAGGTGAGCGAGGCGCTGGAGGCCTGCCAGCGTGCGCTCGCGATCG
AGCCGAACTCGGCAAAGGCGCTGAACCAGATCGGTCAATGCCACGCGCTGCTGGGCGATGCGCAGGCCGCTGTCGCCTGT
TTCGATGCCGCGCTCGCGATCGACCCGGCCGACGAGATCGCGCTGGAGAGCCGGATCTTCTCATTGGATTTCTGCGAGGT
CGGCTTTGCTCAGCATCAGGCGGCCCGGTCGGAGTGGTGGCGCCGGATCGGCTCCAAGATCGCCGAGATGCATCCGCCTC
ACCATGCCAATGATCCCGATCCCGATCGACGGATCGTCGTGGGCTACGTGTCGGGTGATTTCAAGGAGCATTCCGCCGCC
CGCACCTTCCGCCCCGTGATCCAGAGCCATGACAAGTCGCAGGTCGAGGTGATCTGCTACTCGAATTCGCCGATTCAGGA
CGCGATCACGGACACGTTCCGGCAGGCCGCCGATCGATGGCGCGACGTGACGCAATGGTCCGACGATCAGCTCGCAGATT
GCATCGGGGTCGACAAGGTCGACATCCTCGTCGACCTGTCCGGGCACTCGCGCGGCAACCGGCTGAGCACCTTTGCGCGC
AAGCCGGCCCCCATCCAGGTCACCGCGTGGGGCCATGCGACCGGCACCGGCCTGGCGACGATGGATTATCTGTTCGGCGA
TCCGGTCATGGCGCCTCCGGAGATGCGTCACCTGTTTACGGAGCAGATCTACGATCTGCCAAGCTTGATCATCATCGAGC
CGCCGCCTTCGGGACTGCGCAGCCTCGAGGCCCCGGTGACGTCCAACGGCCATGTCACCTACGGCGCGTTCACCAGGGCG
AACCGGTTGTCCAGTGCCGTCCTCGACGTCTGGGCCCGCATCCTGCGCGCCGACGTCGCCGCCCGATTGCTGGTCAAGGA
TTATCTGCTCAGCGATGCTGCGATCCAGGCCAGGCTGCTGGCCGACTTCGCCGCGCGCGGCATCGCGCCGGAGCGTATCG
ACCTGATCGGGCCGACCTCCCGCGACGAGCATCTGGCTGCGCACCGGCTGATCGACATCTGGCTCGATCCTTTTCCCAAT
GGCGGCGGCGTCTCGGTCTGGGAAGCCCTGCACATGGGCGTGCCGGTCGTATCGAAGCTCGGCAACGGAATGTGCAGCCG
GGCCGGCGGCGCGATCCTGTCGGCGATCGGCATGGCCGACTGGGTCGCCACCGATGACGATGAGTATGTGGACATCGCCT
TGCGCGCGACGCCGGACCGGCTCAACACGCTCCGTCGCCAGCTCCCCGACCTCATCGCGGAACGCTGCGCTCCGTCCGTC
TACACCAGGGCTGTCGAAGCGGCCTATCGCACGATGTGGCAGACCTATTGCCGCGGTCGGCGGGCCTGA

Upstream 100 bases:

>100_bases
GCACTGCCCCTCGCAACATGCTTAATGAATTGTTTACGCCTCTCACCGAAGCTCCGGCGGGCGACCGAATGACGCTCGCA
TTCCGGCATTCTGCCCTGTC

Downstream 100 bases:

>100_bases
GCGCCTGTGTTCTCGACAACTGGCCCCGCTCTGTGAGCACAGCCGAGCCGCATGGCGCGCGCTGCCGTAGGGCGGGTAAA
GGAGCTGGTGCGGGGTGAAG

Product: O-linked N-acetylglucosamine transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 742; Mature: 741

Protein sequence:

>742_residues
MTEHDDGGRSLDIFSMQPALRKRDDVADLFAQASAFHRSGDLAKAQAGYRKILKKRPNHFGALYQLGLSEHQSRKSDEAE
RLLKRALLVEPRSVEARYARAVVLSALQRDSEALSCFDDLLALKPDLFDAHLERGKLLSRLRRFADAAVSYDHAMLINPQ
RLDVLINKGEALHYLGRFVDAIACYDQLLAAHPTHLAALINRGCAFKDLRRADEAIADFDRALALSPDDTIALINRGETF
LTLKRNADALHDFDRVIALDPQFALGWLGRANVLMLNKQVSEALEACQRALAIEPNSAKALNQIGQCHALLGDAQAAVAC
FDAALAIDPADEIALESRIFSLDFCEVGFAQHQAARSEWWRRIGSKIAEMHPPHHANDPDPDRRIVVGYVSGDFKEHSAA
RTFRPVIQSHDKSQVEVICYSNSPIQDAITDTFRQAADRWRDVTQWSDDQLADCIGVDKVDILVDLSGHSRGNRLSTFAR
KPAPIQVTAWGHATGTGLATMDYLFGDPVMAPPEMRHLFTEQIYDLPSLIIIEPPPSGLRSLEAPVTSNGHVTYGAFTRA
NRLSSAVLDVWARILRADVAARLLVKDYLLSDAAIQARLLADFAARGIAPERIDLIGPTSRDEHLAAHRLIDIWLDPFPN
GGGVSVWEALHMGVPVVSKLGNGMCSRAGGAILSAIGMADWVATDDDEYVDIALRATPDRLNTLRRQLPDLIAERCAPSV
YTRAVEAAYRTMWQTYCRGRRA

Sequences:

>Translated_742_residues
MTEHDDGGRSLDIFSMQPALRKRDDVADLFAQASAFHRSGDLAKAQAGYRKILKKRPNHFGALYQLGLSEHQSRKSDEAE
RLLKRALLVEPRSVEARYARAVVLSALQRDSEALSCFDDLLALKPDLFDAHLERGKLLSRLRRFADAAVSYDHAMLINPQ
RLDVLINKGEALHYLGRFVDAIACYDQLLAAHPTHLAALINRGCAFKDLRRADEAIADFDRALALSPDDTIALINRGETF
LTLKRNADALHDFDRVIALDPQFALGWLGRANVLMLNKQVSEALEACQRALAIEPNSAKALNQIGQCHALLGDAQAAVAC
FDAALAIDPADEIALESRIFSLDFCEVGFAQHQAARSEWWRRIGSKIAEMHPPHHANDPDPDRRIVVGYVSGDFKEHSAA
RTFRPVIQSHDKSQVEVICYSNSPIQDAITDTFRQAADRWRDVTQWSDDQLADCIGVDKVDILVDLSGHSRGNRLSTFAR
KPAPIQVTAWGHATGTGLATMDYLFGDPVMAPPEMRHLFTEQIYDLPSLIIIEPPPSGLRSLEAPVTSNGHVTYGAFTRA
NRLSSAVLDVWARILRADVAARLLVKDYLLSDAAIQARLLADFAARGIAPERIDLIGPTSRDEHLAAHRLIDIWLDPFPN
GGGVSVWEALHMGVPVVSKLGNGMCSRAGGAILSAIGMADWVATDDDEYVDIALRATPDRLNTLRRQLPDLIAERCAPSV
YTRAVEAAYRTMWQTYCRGRRA
>Mature_741_residues
TEHDDGGRSLDIFSMQPALRKRDDVADLFAQASAFHRSGDLAKAQAGYRKILKKRPNHFGALYQLGLSEHQSRKSDEAER
LLKRALLVEPRSVEARYARAVVLSALQRDSEALSCFDDLLALKPDLFDAHLERGKLLSRLRRFADAAVSYDHAMLINPQR
LDVLINKGEALHYLGRFVDAIACYDQLLAAHPTHLAALINRGCAFKDLRRADEAIADFDRALALSPDDTIALINRGETFL
TLKRNADALHDFDRVIALDPQFALGWLGRANVLMLNKQVSEALEACQRALAIEPNSAKALNQIGQCHALLGDAQAAVACF
DAALAIDPADEIALESRIFSLDFCEVGFAQHQAARSEWWRRIGSKIAEMHPPHHANDPDPDRRIVVGYVSGDFKEHSAAR
TFRPVIQSHDKSQVEVICYSNSPIQDAITDTFRQAADRWRDVTQWSDDQLADCIGVDKVDILVDLSGHSRGNRLSTFARK
PAPIQVTAWGHATGTGLATMDYLFGDPVMAPPEMRHLFTEQIYDLPSLIIIEPPPSGLRSLEAPVTSNGHVTYGAFTRAN
RLSSAVLDVWARILRADVAARLLVKDYLLSDAAIQARLLADFAARGIAPERIDLIGPTSRDEHLAAHRLIDIWLDPFPNG
GGVSVWEALHMGVPVVSKLGNGMCSRAGGAILSAIGMADWVATDDDEYVDIALRATPDRLNTLRRQLPDLIAERCAPSVY
TRAVEAAYRTMWQTYCRGRRA

Specific function: Unknown

COG id: COG3914

COG function: function code O; Predicted O-linked N-acetylglucosamine transferase, SPINDLY family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=619, Percent_Identity=24.3941841680129, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI32307148, Length=619, Percent_Identity=24.3941841680129, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI301336134, Length=293, Percent_Identity=25.5972696245734, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI310110582, Length=324, Percent_Identity=25, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI310131789, Length=324, Percent_Identity=25, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI83415184, Length=293, Percent_Identity=25.5972696245734, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI310123097, Length=324, Percent_Identity=25, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI167466177, Length=283, Percent_Identity=24.3816254416961, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI167466175, Length=283, Percent_Identity=24.3816254416961, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115532692, Length=526, Percent_Identity=23.7642585551331, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI115532690, Length=521, Percent_Identity=23.8003838771593, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI25147174, Length=218, Percent_Identity=24.7706422018349, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17647755, Length=513, Percent_Identity=24.7563352826511, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24585827, Length=513, Percent_Identity=24.7563352826511, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24585829, Length=513, Percent_Identity=24.7563352826511, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24647123, Length=250, Percent_Identity=24, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 82052; Mature: 81921

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHDDGGRSLDIFSMQPALRKRDDVADLFAQASAFHRSGDLAKAQAGYRKILKKRPNHF
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHH
GALYQLGLSEHQSRKSDEAERLLKRALLVEPRSVEARYARAVVLSALQRDSEALSCFDDL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHH
LALKPDLFDAHLERGKLLSRLRRFADAAVSYDHAMLINPQRLDVLINKGEALHYLGRFVD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHEEEEECCCHHHHHHHHHHH
AIACYDQLLAAHPTHLAALINRGCAFKDLRRADEAIADFDRALALSPDDTIALINRGETF
HHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCEE
LTLKRNADALHDFDRVIALDPQFALGWLGRANVLMLNKQVSEALEACQRALAIEPNSAKA
EEEECCCHHHHHHHHHEEECCCHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHH
LNQIGQCHALLGDAQAAVACFDAALAIDPADEIALESRIFSLDFCEVGFAQHQAARSEWW
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHH
RRIGSKIAEMHPPHHANDPDPDRRIVVGYVSGDFKEHSAARTFRPVIQSHDKSQVEVICY
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
SNSPIQDAITDTFRQAADRWRDVTQWSDDQLADCIGVDKVDILVDLSGHSRGNRLSTFAR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHC
KPAPIQVTAWGHATGTGLATMDYLFGDPVMAPPEMRHLFTEQIYDLPSLIIIEPPPSGLR
CCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHH
SLEAPVTSNGHVTYGAFTRANRLSSAVLDVWARILRADVAARLLVKDYLLSDAAIQARLL
HCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADFAARGIAPERIDLIGPTSRDEHLAAHRLIDIWLDPFPNGGGVSVWEALHMGVPVVSKL
HHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHH
GNGMCSRAGGAILSAIGMADWVATDDDEYVDIALRATPDRLNTLRRQLPDLIAERCAPSV
CCCHHHHHCHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCHHH
YTRAVEAAYRTMWQTYCRGRRA
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEHDDGGRSLDIFSMQPALRKRDDVADLFAQASAFHRSGDLAKAQAGYRKILKKRPNHF
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHH
GALYQLGLSEHQSRKSDEAERLLKRALLVEPRSVEARYARAVVLSALQRDSEALSCFDDL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHH
LALKPDLFDAHLERGKLLSRLRRFADAAVSYDHAMLINPQRLDVLINKGEALHYLGRFVD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHEEEEECCCHHHHHHHHHHH
AIACYDQLLAAHPTHLAALINRGCAFKDLRRADEAIADFDRALALSPDDTIALINRGETF
HHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCEE
LTLKRNADALHDFDRVIALDPQFALGWLGRANVLMLNKQVSEALEACQRALAIEPNSAKA
EEEECCCHHHHHHHHHEEECCCHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHH
LNQIGQCHALLGDAQAAVACFDAALAIDPADEIALESRIFSLDFCEVGFAQHQAARSEWW
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHH
RRIGSKIAEMHPPHHANDPDPDRRIVVGYVSGDFKEHSAARTFRPVIQSHDKSQVEVICY
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
SNSPIQDAITDTFRQAADRWRDVTQWSDDQLADCIGVDKVDILVDLSGHSRGNRLSTFAR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHC
KPAPIQVTAWGHATGTGLATMDYLFGDPVMAPPEMRHLFTEQIYDLPSLIIIEPPPSGLR
CCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHH
SLEAPVTSNGHVTYGAFTRANRLSSAVLDVWARILRADVAARLLVKDYLLSDAAIQARLL
HCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADFAARGIAPERIDLIGPTSRDEHLAAHRLIDIWLDPFPNGGGVSVWEALHMGVPVVSKL
HHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHH
GNGMCSRAGGAILSAIGMADWVATDDDEYVDIALRATPDRLNTLRRQLPDLIAERCAPSV
CCCHHHHHCHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCHHH
YTRAVEAAYRTMWQTYCRGRRA
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]