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The map label for this gene is bdlA [H]

Identifier: 146338351

GI number: 146338351

Start: 1347458

End: 1349137

Strand: Reverse

Name: bdlA [H]

Synonym: BRADO1259

Alternate gene names: 146338351

Gene position: 1349137-1347458 (Counterclockwise)

Preceding gene: 146338352

Following gene: 146338350

Centisome position: 18.09

GC content: 61.79

Gene sequence:

>1680_bases
ATGGCGTTCTGGGCATTCGGATCTGACCGCGGCGCGACCTCGCCGCTCAGAGTGGCTCTCGACAAGTCGCTTGCCATGAT
GGCAGTCGCGATGGACGGCACGATCATTTCGGCGAACGAGAACTGCCTGGGAGCGCTGGGCTATACGTCTGCGGAAGTCG
AAGGCCGGCAGCACAGCATGCTGATCGATCCCGCCGCTCAAGCCGACGGGTCCTACCAGAAGTTCTGGGACAGCCTCCGG
CGTGGGGAGTTTCAATCCGGCGAGTTCAAGCGGATCGGCAAGGGCGGCAAGACGCTCTGGATCCAGGGAACATATACGCC
GATTCTCGATCGCAACGGCAAGCCGACCAAGGTGATCAAGCTCGCGACGGATGTGACGGCGCAGAAGGCGCGCAGCCTGG
AGAACGACGCCATCATGGCCGCGCTGCTTCGGTCGCAAACCGCGATCGAGTGCAAGATGGACGGCACGATCATCACCGTG
AACCAGAACCTGCTCGACCAGCTCGGCTACACGCTGGAGGAGGTTCGCGGCAAGCACCAGAGCATGTTCATCGACCCCGC
CGCGCGGGACAGCGCCGAATATCGCGGATTCTGGGCCACGTTGCGGGCCGGCAAACATTGCGCGGCCGAGTTCAAGCGGC
GAGCCAAATCCGGAAAAGATGTCTGGGTCGTGGGCAGTTGGAATCCGATCCTGGACGAGAAGGGCCAACCCTACAAGGTG
GTGGGCTTTGCAACCGACGTGACGGCACAGAAGCTGGAAGCGATCGACTTCGCGGGTCAGATCGAGGCGATCAGCAAGTC
GATGGCGGTCACCGAGTTTGCGCTGGACGGCACGATCTTGAAAGCCAACAAGATCTTCCTCGACATGATGGGTTATTCCG
ACAAGGAGGTTGTCGGCAAGCATCACAGCATGTTCGTGCCCGAGGTCGAGCACAACACTCCGGCGTACCGGGAGTTCTGG
AGCAAGCTGCGCGCTGGCGAAGCTCAGACCGGCGAATTCCTGCGCATGAGCAAGGACAACCGCGAAGTCTACATTCACGG
CAGCTACAATCCGATTTTCGATCTGGACGGCAAGCCGATGAAGATCGTGAAATACGCCTACGACATGACCCCGACGGTCA
TCGCCCGGCAGAAGAGCGGCTCGGTTCGCTTCATCATCGAATCCGTGGCCGACGGCGCGGAGAATCTAAGGACGTCCGTC
CGCGATATTTCAGACGCGATGGACAAATGCCAGATGAAGACGTCCGAAGCGGTCGGGCATGTCGACGCCGCGGATCAGCA
GGCCAAACAGCTGACGGCGGCGACGGACGCAATGGGAGGCATCGTCGAGCTGATCGGCAATATCACCGGGCAGATCAACC
TGCTGGCCCTCAACGCGACCATCGAATCGGCCCGCGCTGGCGATGCCGGTCGCGGCTTCGCGGTCGTGGCGTCCGAGGTG
AAGAACCTGGCCAATCAGGCGAAGCAGGCGACCGACAAGATCGGGTCGGAGATCGGCAACCTGAACCTCATCTCGGGCGA
CGTCGTCGTCGCGCTCAGGACGATCAAGGGGGCGATCGAGAGCGTCAGCGAATACGTCATCGCCTCGACCACCGCCGTCA
AGGAGCAGAGCGAGATGAGCGAGGTGATCTCCGGCAGCATCCGCACCGCCGCGTCGGAAGCCGCGGGCATTGTGGTCTGA

Upstream 100 bases:

>100_bases
TGTGGGACCGCCAGCGACGACGGCTCACCGGTTACGCGCGGCGTCCGTCGCGGGCGTGACTGGATACGTACGTAATCGCG
ACGGCACCAAGGGTATTTGC

Downstream 100 bases:

>100_bases
TGCAAACACGGCGCGCGGCCCCTCGGGCGAACGCCGTGACCGGCGGGTCGGAAGGTCGGTCATGGGGCTGCAAGCCCGAA
AGGACTACCGAACGCTGGAG

Product: methyl-accepting chemotaxis receptor/sensory transducer

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MAFWAFGSDRGATSPLRVALDKSLAMMAVAMDGTIISANENCLGALGYTSAEVEGRQHSMLIDPAAQADGSYQKFWDSLR
RGEFQSGEFKRIGKGGKTLWIQGTYTPILDRNGKPTKVIKLATDVTAQKARSLENDAIMAALLRSQTAIECKMDGTIITV
NQNLLDQLGYTLEEVRGKHQSMFIDPAARDSAEYRGFWATLRAGKHCAAEFKRRAKSGKDVWVVGSWNPILDEKGQPYKV
VGFATDVTAQKLEAIDFAGQIEAISKSMAVTEFALDGTILKANKIFLDMMGYSDKEVVGKHHSMFVPEVEHNTPAYREFW
SKLRAGEAQTGEFLRMSKDNREVYIHGSYNPIFDLDGKPMKIVKYAYDMTPTVIARQKSGSVRFIIESVADGAENLRTSV
RDISDAMDKCQMKTSEAVGHVDAADQQAKQLTAATDAMGGIVELIGNITGQINLLALNATIESARAGDAGRGFAVVASEV
KNLANQAKQATDKIGSEIGNLNLISGDVVVALRTIKGAIESVSEYVIASTTAVKEQSEMSEVISGSIRTAASEAAGIVV

Sequences:

>Translated_559_residues
MAFWAFGSDRGATSPLRVALDKSLAMMAVAMDGTIISANENCLGALGYTSAEVEGRQHSMLIDPAAQADGSYQKFWDSLR
RGEFQSGEFKRIGKGGKTLWIQGTYTPILDRNGKPTKVIKLATDVTAQKARSLENDAIMAALLRSQTAIECKMDGTIITV
NQNLLDQLGYTLEEVRGKHQSMFIDPAARDSAEYRGFWATLRAGKHCAAEFKRRAKSGKDVWVVGSWNPILDEKGQPYKV
VGFATDVTAQKLEAIDFAGQIEAISKSMAVTEFALDGTILKANKIFLDMMGYSDKEVVGKHHSMFVPEVEHNTPAYREFW
SKLRAGEAQTGEFLRMSKDNREVYIHGSYNPIFDLDGKPMKIVKYAYDMTPTVIARQKSGSVRFIIESVADGAENLRTSV
RDISDAMDKCQMKTSEAVGHVDAADQQAKQLTAATDAMGGIVELIGNITGQINLLALNATIESARAGDAGRGFAVVASEV
KNLANQAKQATDKIGSEIGNLNLISGDVVVALRTIKGAIESVSEYVIASTTAVKEQSEMSEVISGSIRTAASEAAGIVV
>Mature_558_residues
AFWAFGSDRGATSPLRVALDKSLAMMAVAMDGTIISANENCLGALGYTSAEVEGRQHSMLIDPAAQADGSYQKFWDSLRR
GEFQSGEFKRIGKGGKTLWIQGTYTPILDRNGKPTKVIKLATDVTAQKARSLENDAIMAALLRSQTAIECKMDGTIITVN
QNLLDQLGYTLEEVRGKHQSMFIDPAARDSAEYRGFWATLRAGKHCAAEFKRRAKSGKDVWVVGSWNPILDEKGQPYKVV
GFATDVTAQKLEAIDFAGQIEAISKSMAVTEFALDGTILKANKIFLDMMGYSDKEVVGKHHSMFVPEVEHNTPAYREFWS
KLRAGEAQTGEFLRMSKDNREVYIHGSYNPIFDLDGKPMKIVKYAYDMTPTVIARQKSGSVRFIIESVADGAENLRTSVR
DISDAMDKCQMKTSEAVGHVDAADQQAKQLTAATDAMGGIVELIGNITGQINLLALNATIESARAGDAGRGFAVVASEVK
NLANQAKQATDKIGSEIGNLNLISGDVVVALRTIKGAIESVSEYVIASTTAVKEQSEMSEVISGSIRTAASEAAGIVV

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=110, Percent_Identity=40.9090909090909, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788194, Length=119, Percent_Identity=36.1344537815126, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787690, Length=125, Percent_Identity=38.4, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788195, Length=120, Percent_Identity=36.6666666666667, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789453, Length=61, Percent_Identity=50.8196721311475, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 60525; Mature: 60394

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFWAFGSDRGATSPLRVALDKSLAMMAVAMDGTIISANENCLGALGYTSAEVEGRQHSM
CEEEEECCCCCCCCCHHHHHHHHHEEEEEEECCEEEECCCCCEEECCCCCCCCCCCCCEE
LIDPAAQADGSYQKFWDSLRRGEFQSGEFKRIGKGGKTLWIQGTYTPILDRNGKPTKVIK
EECCHHCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEECCCHHCCCCCCCCEEEE
LATDVTAQKARSLENDAIMAALLRSQTAIECKMDGTIITVNQNLLDQLGYTLEEVRGKHQ
EEHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCEEEEECHHHHHHHCCHHHHHCCCCC
SMFIDPAARDSAEYRGFWATLRAGKHCAAEFKRRAKSGKDVWVVGSWNPILDEKGQPYKV
EEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCCEEE
VGFATDVTAQKLEAIDFAGQIEAISKSMAVTEFALDGTILKANKIFLDMMGYSDKEVVGK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEECCEEEEEECCCCCHHHHCC
HHSMFVPEVEHNTPAYREFWSKLRAGEAQTGEFLRMSKDNREVYIHGSYNPIFDLDGKPM
CCCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEEECCCCEEECCCCCE
KIVKYAYDMTPTVIARQKSGSVRFIIESVADGAENLRTSVRDISDAMDKCQMKTSEAVGH
EEEEEHHCCCCCEEEECCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VDAADQQAKQLTAATDAMGGIVELIGNITGQINLLALNATIESARAGDAGRGFAVVASEV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHCCCCCCCCCHHHHHHHH
KNLANQAKQATDKIGSEIGNLNLISGDVVVALRTIKGAIESVSEYVIASTTAVKEQSEMS
HHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVISGSIRTAASEAAGIVV
HHHCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
AFWAFGSDRGATSPLRVALDKSLAMMAVAMDGTIISANENCLGALGYTSAEVEGRQHSM
EEEEECCCCCCCCCHHHHHHHHHEEEEEEECCEEEECCCCCEEECCCCCCCCCCCCCEE
LIDPAAQADGSYQKFWDSLRRGEFQSGEFKRIGKGGKTLWIQGTYTPILDRNGKPTKVIK
EECCHHCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEECCCHHCCCCCCCCEEEE
LATDVTAQKARSLENDAIMAALLRSQTAIECKMDGTIITVNQNLLDQLGYTLEEVRGKHQ
EEHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCEEEEECHHHHHHHCCHHHHHCCCCC
SMFIDPAARDSAEYRGFWATLRAGKHCAAEFKRRAKSGKDVWVVGSWNPILDEKGQPYKV
EEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCCEEE
VGFATDVTAQKLEAIDFAGQIEAISKSMAVTEFALDGTILKANKIFLDMMGYSDKEVVGK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEECCEEEEEECCCCCHHHHCC
HHSMFVPEVEHNTPAYREFWSKLRAGEAQTGEFLRMSKDNREVYIHGSYNPIFDLDGKPM
CCCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEEECCCCEEECCCCCE
KIVKYAYDMTPTVIARQKSGSVRFIIESVADGAENLRTSVRDISDAMDKCQMKTSEAVGH
EEEEEHHCCCCCEEEECCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VDAADQQAKQLTAATDAMGGIVELIGNITGQINLLALNATIESARAGDAGRGFAVVASEV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHCCCCCCCCCHHHHHHHH
KNLANQAKQATDKIGSEIGNLNLISGDVVVALRTIKGAIESVSEYVIASTTAVKEQSEMS
HHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVISGSIRTAASEAAGIVV
HHHCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]