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The map label for this gene is atoD [H]

Identifier: 146338318

GI number: 146338318

Start: 1300798

End: 1301526

Strand: Direct

Name: atoD [H]

Synonym: BRADO1223

Alternate gene names: 146338318

Gene position: 1300798-1301526 (Clockwise)

Preceding gene: 146338312

Following gene: 146338319

Centisome position: 17.44

GC content: 64.2

Gene sequence:

>729_bases
ATGAACAAGGTCTATCCGGACGCCAAAACCGCCCTTGCGGGCCTCCTCAAGGACGGCATGACCATCATGTCCGGCGGGTT
TGGCCTTTGCGGCATCGCAGAAACGCTGTCCGATGCCATTCGCGAGTCCGGCGTCAAGGACCTCACCGTCATCTCCAACA
ACGCCGGCGTCGACGGCATCGGCTTGAGCCGACTGCTCGAGACGCGGCAGATCAAGAAGATGATCTCGTCCTATGTCGGC
GAGAATAAGCTGTTCGCACAGCAATATCTGGCCGGCGAGCTGGAGCTCGAGTTCTGTCCGCAGGGCACCCTGGCCGAGCG
CATCCGCGCCGGCGGCGCCGGCATTCCGGCGTTCTTCACCAAGACCGGCGTCGGCACGCTGGTCGCCGAAGGCAAGGAGG
TGCGCGAGTTCGACGGCGAAAAATATCTGATGGAGCGCGGCCTGTTCGCCGACATCGCCATCGTGCACGCCTGGAAGGGC
GATACCGCCGGCAACCTCGTCTACAGGAAGACCGCGCGCAACTTCAACCCGATGATGGCCACGGCGGCCAAGGTGACTGT
GGCCGAGGTCGAGCATCTGCTCCCGGCCGGCCAGATCGATCCCGACCACATCCACACGCCGGGCATCTTCGTGAAGCGCA
TCATCCAGGTCGGGACCGCGCTCAAGCGCATCGAGCAGCGCACCGTGCGCAAACGTGAAGCCGCCGCTGCAGCCGGGGAG
GAAGTCTGA

Upstream 100 bases:

>100_bases
GATGCCCGTTGGGAAGGCATCATTGACGCATTGCGAAGATTTCGCCTAATAATCCGGTCGATCTCCGCGCCGTCCTCGCT
TTGCATCAGGTCATTTCCGT

Downstream 100 bases:

>100_bases
TGGCCTGGACGCGAGAGCAGATGGCGGCGCGCGCCGCCAAGGAGCTGCGGGACGGCTACTACGTCAATCTCGGCATCGGT
ATCCCGACGCTGGTCTCGAA

Product: acetyl-CoA:acetoacetyl-CoA transferase subunit alpha

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNKVYPDAKTALAGLLKDGMTIMSGGFGLCGIAETLSDAIRESGVKDLTVISNNAGVDGIGLSRLLETRQIKKMISSYVG
ENKLFAQQYLAGELELEFCPQGTLAERIRAGGAGIPAFFTKTGVGTLVAEGKEVREFDGEKYLMERGLFADIAIVHAWKG
DTAGNLVYRKTARNFNPMMATAAKVTVAEVEHLLPAGQIDPDHIHTPGIFVKRIIQVGTALKRIEQRTVRKREAAAAAGE
EV

Sequences:

>Translated_242_residues
MNKVYPDAKTALAGLLKDGMTIMSGGFGLCGIAETLSDAIRESGVKDLTVISNNAGVDGIGLSRLLETRQIKKMISSYVG
ENKLFAQQYLAGELELEFCPQGTLAERIRAGGAGIPAFFTKTGVGTLVAEGKEVREFDGEKYLMERGLFADIAIVHAWKG
DTAGNLVYRKTARNFNPMMATAAKVTVAEVEHLLPAGQIDPDHIHTPGIFVKRIIQVGTALKRIEQRTVRKREAAAAAGE
EV
>Mature_242_residues
MNKVYPDAKTALAGLLKDGMTIMSGGFGLCGIAETLSDAIRESGVKDLTVISNNAGVDGIGLSRLLETRQIKKMISSYVG
ENKLFAQQYLAGELELEFCPQGTLAERIRAGGAGIPAFFTKTGVGTLVAEGKEVREFDGEKYLMERGLFADIAIVHAWKG
DTAGNLVYRKTARNFNPMMATAAKVTVAEVEHLLPAGQIDPDHIHTPGIFVKRIIQVGTALKRIEQRTVRKREAAAAAGE
EV

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=52.2267206477733, Blast_Score=255, Evalue=2e-68,
Organism=Homo sapiens, GI11545841, Length=244, Percent_Identity=52.0491803278688, Blast_Score=240, Evalue=8e-64,
Organism=Escherichia coli, GI1788551, Length=203, Percent_Identity=45.320197044335, Blast_Score=192, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=251, Percent_Identity=48.605577689243, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI21358325, Length=242, Percent_Identity=50.4132231404959, Blast_Score=242, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24655794, Length=242, Percent_Identity=50.4132231404959, Blast_Score=242, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 26049; Mature: 26049

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVYPDAKTALAGLLKDGMTIMSGGFGLCGIAETLSDAIRESGVKDLTVISNNAGVDGI
CCCCCCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCH
GLSRLLETRQIKKMISSYVGENKLFAQQYLAGELELEFCPQGTLAERIRAGGAGIPAFFT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTLVAEGKEVREFDGEKYLMERGLFADIAIVHAWKGDTAGNLVYRKTARNFNPMMA
HCCCHHHHHCCHHHHHHCCHHHHHHCCCHHHHHEEEEECCCCCCCEEEEHHHCCCCHHHH
TAAKVTVAEVEHLLPAGQIDPDHIHTPGIFVKRIIQVGTALKRIEQRTVRKREAAAAAGE
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EV
CC
>Mature Secondary Structure
MNKVYPDAKTALAGLLKDGMTIMSGGFGLCGIAETLSDAIRESGVKDLTVISNNAGVDGI
CCCCCCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCH
GLSRLLETRQIKKMISSYVGENKLFAQQYLAGELELEFCPQGTLAERIRAGGAGIPAFFT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTLVAEGKEVREFDGEKYLMERGLFADIAIVHAWKGDTAGNLVYRKTARNFNPMMA
HCCCHHHHHCCHHHHHHCCHHHHHHCCCHHHHHEEEEECCCCCCCEEEEHHHCCCCHHHH
TAAKVTVAEVEHLLPAGQIDPDHIHTPGIFVKRIIQVGTALKRIEQRTVRKREAAAAAGE
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]