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The map label for this gene is atoC [H]

Identifier: 146338287

GI number: 146338287

Start: 1267618

End: 1269114

Strand: Reverse

Name: atoC [H]

Synonym: BRADO1191

Alternate gene names: 146338287

Gene position: 1269114-1267618 (Counterclockwise)

Preceding gene: 146338300

Following gene: 146338286

Centisome position: 17.02

GC content: 66.27

Gene sequence:

>1497_bases
ATGGCTGCCAGCATTTTGATCGCCGATGATGATCCGGTCCAGCGCCGGCTGGTGGAGAACATGGTGCAGAAATGCGGCTA
CGAGGCGGTCGTCGTCGAGACCGGCGATGCCGTGATCGAGAAGCTGACCAATCCCGACGCGGGTCCCATCGACGCCATCG
TGCTCGACCTCGTGATGCCCGGCCTCGACGGCATGGGCGTGCTGTCGAAGATGCGCGAAGCCGGGATCTCGATCCCCGTG
ATCGTGCAGACCGCGCATGGCGGCATCGACAACGTCGTCTCGGCGATGCGCGCCGGCGCGCAGGATTTCGTCGTCAAGCC
GGTCGGCATCGAGCGGCTGCAGGTATCGCTGCGCAACGCACTGAATACCTCCGCACTCAAGGGCGAACTGCAGCGCATCC
GTCACAGCCGCGAGGGCCGGCTGACCTTCTCGGACATCGTCACCCGCGCCGAAGCGATGGCGCCGATCCTGCGCATCGCC
GAGAAGGCCGCGGCCTCATCGATTCCCGTGCTGATCGAGGGCGAATCCGGCGTCGGCAAGGAGCTGTTCGCCCGCGCCAT
CCATGGCACCAGCGAGCGCAAGACCAAGCCGTTCGTCGCGGTGAATTGCGGCGCAATCCCGGACAATCTCGTCGAATCGA
TCCTGTTCGGCCACGAGAAGGGCGCGTTCACCGGCGCGACCGACCGCCACACCGGCAAGTTCGTCGAAGCCCATGGCGGC
ACCTTGTTCCTCGACGAGGTCTCTGAGCTGCCGCTCACTGCGCAGGTCAAGCTGCTGCGCGCCTTGCAGGAGGGCGCTGT
CGAGGCGGTCGGTGGCCGCAAGCCGGTCAAGGTCGATGTGCGCATCATCTCGGCAACCAACCGCCGCCTGCTCGACCGGG
TCAAGGAAGGACATTTCCGCGAGGACCTGTTCTACCGGCTGCACGTGCTGCCGCTGACGATCCCTCCCTTGCGCGCGCGC
CGCGAGGACATTCCGCATCTGCTGCGGCATTTCCTGGCGCGCTTTTCAGCCGAGGAAAATCGCCCTGTGTCGGGCATCAG
CGGCGACGCGGTGGCGTATCTGACCAAGCTCGACTGGCCGGGCAACATCCGCCAGCTCGAGAACGCCGTCTATCGCGCCG
TCGTCATGAGCGAGACCGACCAACTCGGCGTCAACGACTTCCCGCTGATACCGACCCATGCGCCGCCCGTCGAGCCGGCG
CCACCCCTGGTCGTGGAGCGCCCCGCTCAGGCCACGCTGCCGGCGATGGTGCCGGGTAGTGAAGTACCCATTGCACCCCT
GCCCTCGCATGGCAGCCTGCCCATGCTCAACGCCGGTGGCGACGTCCGGCCGCTGGAGGAGATGGAGCACGAGATCATCC
GCTTCGCCATCGCTCATTACCGCGGTCAGATGTCGGAGGTGGCGCGGCGTCTCAAAATCGGACGCTCGACGCTCTACCGC
AAGCTCGACGAGGCCAATGGCGAGACGCCATCGACGGAATCGCCGCCGCTCGGATGA

Upstream 100 bases:

>100_bases
CGAACGTTTATCCCGATCAGCGAGGTTTAAGGTTGCGTTAATCGGCGTCGGCGAGAGTGCCCCGATTCGAGACAGATAGT
CGTAGCGTGCAAGGAAAGCC

Downstream 100 bases:

>100_bases
TCCGCTCGCGTCCGAAATTCGCCGCAACCCTGCGCAACAACGGAACATCTGAACCGTTGCCTTGCGGTGACAGACAGAGG
AAAAAACGCGTGGCACAAGC

Product: putative response regulator in two-component regulatory system, sigma 54-dependent

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MAASILIADDDPVQRRLVENMVQKCGYEAVVVETGDAVIEKLTNPDAGPIDAIVLDLVMPGLDGMGVLSKMREAGISIPV
IVQTAHGGIDNVVSAMRAGAQDFVVKPVGIERLQVSLRNALNTSALKGELQRIRHSREGRLTFSDIVTRAEAMAPILRIA
EKAAASSIPVLIEGESGVGKELFARAIHGTSERKTKPFVAVNCGAIPDNLVESILFGHEKGAFTGATDRHTGKFVEAHGG
TLFLDEVSELPLTAQVKLLRALQEGAVEAVGGRKPVKVDVRIISATNRRLLDRVKEGHFREDLFYRLHVLPLTIPPLRAR
REDIPHLLRHFLARFSAEENRPVSGISGDAVAYLTKLDWPGNIRQLENAVYRAVVMSETDQLGVNDFPLIPTHAPPVEPA
PPLVVERPAQATLPAMVPGSEVPIAPLPSHGSLPMLNAGGDVRPLEEMEHEIIRFAIAHYRGQMSEVARRLKIGRSTLYR
KLDEANGETPSTESPPLG

Sequences:

>Translated_498_residues
MAASILIADDDPVQRRLVENMVQKCGYEAVVVETGDAVIEKLTNPDAGPIDAIVLDLVMPGLDGMGVLSKMREAGISIPV
IVQTAHGGIDNVVSAMRAGAQDFVVKPVGIERLQVSLRNALNTSALKGELQRIRHSREGRLTFSDIVTRAEAMAPILRIA
EKAAASSIPVLIEGESGVGKELFARAIHGTSERKTKPFVAVNCGAIPDNLVESILFGHEKGAFTGATDRHTGKFVEAHGG
TLFLDEVSELPLTAQVKLLRALQEGAVEAVGGRKPVKVDVRIISATNRRLLDRVKEGHFREDLFYRLHVLPLTIPPLRAR
REDIPHLLRHFLARFSAEENRPVSGISGDAVAYLTKLDWPGNIRQLENAVYRAVVMSETDQLGVNDFPLIPTHAPPVEPA
PPLVVERPAQATLPAMVPGSEVPIAPLPSHGSLPMLNAGGDVRPLEEMEHEIIRFAIAHYRGQMSEVARRLKIGRSTLYR
KLDEANGETPSTESPPLG
>Mature_497_residues
AASILIADDDPVQRRLVENMVQKCGYEAVVVETGDAVIEKLTNPDAGPIDAIVLDLVMPGLDGMGVLSKMREAGISIPVI
VQTAHGGIDNVVSAMRAGAQDFVVKPVGIERLQVSLRNALNTSALKGELQRIRHSREGRLTFSDIVTRAEAMAPILRIAE
KAAASSIPVLIEGESGVGKELFARAIHGTSERKTKPFVAVNCGAIPDNLVESILFGHEKGAFTGATDRHTGKFVEAHGGT
LFLDEVSELPLTAQVKLLRALQEGAVEAVGGRKPVKVDVRIISATNRRLLDRVKEGHFREDLFYRLHVLPLTIPPLRARR
EDIPHLLRHFLARFSAEENRPVSGISGDAVAYLTKLDWPGNIRQLENAVYRAVVMSETDQLGVNDFPLIPTHAPPVEPAP
PLVVERPAQATLPAMVPGSEVPIAPLPSHGSLPMLNAGGDVRPLEEMEHEIIRFAIAHYRGQMSEVARRLKIGRSTLYRK
LDEANGETPSTESPPLG

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=480, Percent_Identity=41.0416666666667, Blast_Score=330, Evalue=9e-92,
Organism=Escherichia coli, GI1790437, Length=479, Percent_Identity=38.2045929018789, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1790299, Length=491, Percent_Identity=40.122199592668, Blast_Score=320, Evalue=2e-88,
Organism=Escherichia coli, GI1788905, Length=378, Percent_Identity=42.8571428571429, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI87082117, Length=272, Percent_Identity=47.4264705882353, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1789233, Length=340, Percent_Identity=41.4705882352941, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1789087, Length=256, Percent_Identity=46.09375, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=46.7532467532467, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI1787583, Length=251, Percent_Identity=43.8247011952191, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1786524, Length=364, Percent_Identity=38.4615384615385, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI87081872, Length=276, Percent_Identity=41.304347826087, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI87081858, Length=336, Percent_Identity=32.1428571428571, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1789828, Length=284, Percent_Identity=32.7464788732394, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788191, Length=114, Percent_Identity=31.5789473684211, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790552, Length=130, Percent_Identity=30, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53993; Mature: 53862

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASILIADDDPVQRRLVENMVQKCGYEAVVVETGDAVIEKLTNPDAGPIDAIVLDLVMP
CCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHC
GLDGMGVLSKMREAGISIPVIVQTAHGGIDNVVSAMRAGAQDFVVKPVGIERLQVSLRNA
CCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHH
LNTSALKGELQRIRHSREGRLTFSDIVTRAEAMAPILRIAEKAAASSIPVLIEGESGVGK
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCH
ELFARAIHGTSERKTKPFVAVNCGAIPDNLVESILFGHEKGAFTGATDRHTGKFVEAHGG
HHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCC
TLFLDEVSELPLTAQVKLLRALQEGAVEAVGGRKPVKVDVRIISATNRRLLDRVKEGHFR
EEEECHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHCCHH
EDLFYRLHVLPLTIPPLRARREDIPHLLRHFLARFSAEENRPVSGISGDAVAYLTKLDWP
HHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCC
GNIRQLENAVYRAVVMSETDQLGVNDFPLIPTHAPPVEPAPPLVVERPAQATLPAMVPGS
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCC
EVPIAPLPSHGSLPMLNAGGDVRPLEEMEHEIIRFAIAHYRGQMSEVARRLKIGRSTLYR
CCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLDEANGETPSTESPPLG
HHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AASILIADDDPVQRRLVENMVQKCGYEAVVVETGDAVIEKLTNPDAGPIDAIVLDLVMP
CCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHC
GLDGMGVLSKMREAGISIPVIVQTAHGGIDNVVSAMRAGAQDFVVKPVGIERLQVSLRNA
CCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHH
LNTSALKGELQRIRHSREGRLTFSDIVTRAEAMAPILRIAEKAAASSIPVLIEGESGVGK
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCH
ELFARAIHGTSERKTKPFVAVNCGAIPDNLVESILFGHEKGAFTGATDRHTGKFVEAHGG
HHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCC
TLFLDEVSELPLTAQVKLLRALQEGAVEAVGGRKPVKVDVRIISATNRRLLDRVKEGHFR
EEEECHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHCCHH
EDLFYRLHVLPLTIPPLRARREDIPHLLRHFLARFSAEENRPVSGISGDAVAYLTKLDWP
HHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCC
GNIRQLENAVYRAVVMSETDQLGVNDFPLIPTHAPPVEPAPPLVVERPAQATLPAMVPGS
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCC
EVPIAPLPSHGSLPMLNAGGDVRPLEEMEHEIIRFAIAHYRGQMSEVARRLKIGRSTLYR
CCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLDEANGETPSTESPPLG
HHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]