BacMap

Definition	Bradyrhizobium sp. ORS278 chromosome, complete genome.
Accession	NC_009445
Length	7,456,587

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The map label for this gene is bdhA [H]

Identifier: 146338178

GI number: 146338178

Start: 1143687

End: 1144478

Strand: Direct

Name: bdhA [H]

Synonym: BRADO1076

Alternate gene names: 146338178

Gene position: 1143687-1144478 (Clockwise)

Preceding gene: 146338177

Following gene: 146338179

Centisome position: 15.34

GC content: 65.03

Gene sequence:

>792_bases
ATGACGACGAATTTGAAGGGCAAGACCGCGGTGGTTACCGGCTCGACCAGCGGCATCGGGCTTGCGATCGCCCGCGGCTT
CGCCTCGGCCGGCGCCAACATCGTGCTCAACGGCTTCGGCGCGCCCGATGACATCGAGAAGGAGCGCGCCAGCATCGAGA
GCGAGTTCAAGGTGAAGGCGGTGCACTCGCCGGCCGACATGAGCAAGCCGGCCGAGATCGCCGGCATGATCGCGCTCGGC
GAGTCCACGTTCGGTTCGGTCGACGTCCTCGTCAACAATGCCGGCATCCAGTTCGTCTCGCCGGTCGAGGATTTTCCGCC
GGAGAAGTGGGAGCAGATCATCGCGATCAATCTCTCTTCCGCGTTCTACGGCATCCACGCCGCCGTCCCCGGCATGAAGA
AGCGCGGCTGGGGCCGCATCATCAACACCGCCTCGGCGCACTCCCTGGTCGCCTCGCCGTTCAAGTCGGCCTATGTCTCG
GCCAAGCACGGCATCGCCGGCCTGACCAAGACGGTCGCGCTCGAGCTCGCCACCTTCAAGATCACCTGCAACTGCATCTC
GCCGGGCTATGTCTGGACGCCGCTGGTCGAAAAGCAGATCCCGGACACGATGAAGGCCCGTAACCTCACCAAGGAGCAGG
TCATCCACGACGTGCTGCTGGCTGCGCAGCCGACCAAGGAATTCGTGACGGTCGACCAGGTCGCCGCGCTTGCGCTGTTC
CTGTGCAGCGACGAGGCGGCGCAGATCACCGGCACCAACCTGTCGATCGACGGCGGCTGGACCGCGGAGTAA

Upstream 100 bases:

>100_bases
CACAAGGACCAGCTGGAGCGCCCCCAGTCCGGCGAAACCATGGTGACCTACGATCTCACGCAGGACGGCAACCTGGCTGC
CGCCAAAAAGGAGTGAAGCA

Downstream 100 bases:

>100_bases
CAACTCTCTCCGTTGTCATCGCCCGGCTTGACCGGGCGATCCAGTACTCACCGGCAGTCGTGAGCCACCGAACGGCCGCA
GCGTACTGGATTCCCCGCCT

Product: D-beta-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTTNLKGKTAVVTGSTSGIGLAIARGFASAGANIVLNGFGAPDDIEKERASIESEFKVKAVHSPADMSKPAEIAGMIALG
ESTFGSVDVLVNNAGIQFVSPVEDFPPEKWEQIIAINLSSAFYGIHAAVPGMKKRGWGRIINTASAHSLVASPFKSAYVS
AKHGIAGLTKTVALELATFKITCNCISPGYVWTPLVEKQIPDTMKARNLTKEQVIHDVLLAAQPTKEFVTVDQVAALALF
LCSDEAAQITGTNLSIDGGWTAE

Sequences:

>Translated_263_residues
MTTNLKGKTAVVTGSTSGIGLAIARGFASAGANIVLNGFGAPDDIEKERASIESEFKVKAVHSPADMSKPAEIAGMIALG
ESTFGSVDVLVNNAGIQFVSPVEDFPPEKWEQIIAINLSSAFYGIHAAVPGMKKRGWGRIINTASAHSLVASPFKSAYVS
AKHGIAGLTKTVALELATFKITCNCISPGYVWTPLVEKQIPDTMKARNLTKEQVIHDVLLAAQPTKEFVTVDQVAALALF
LCSDEAAQITGTNLSIDGGWTAE
>Mature_262_residues
TTNLKGKTAVVTGSTSGIGLAIARGFASAGANIVLNGFGAPDDIEKERASIESEFKVKAVHSPADMSKPAEIAGMIALGE
STFGSVDVLVNNAGIQFVSPVEDFPPEKWEQIIAINLSSAFYGIHAAVPGMKKRGWGRIINTASAHSLVASPFKSAYVSA
KHGIAGLTKTVALELATFKITCNCISPGYVWTPLVEKQIPDTMKARNLTKEQVIHDVLLAAQPTKEFVTVDQVAALALFL
CSDEAAQITGTNLSIDGGWTAE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=30.46875, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI19923817, Length=268, Percent_Identity=27.2388059701493, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI20149619, Length=253, Percent_Identity=30.4347826086957, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI66933014, Length=259, Percent_Identity=32.4324324324324, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4504505, Length=265, Percent_Identity=27.9245283018868, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7705925, Length=263, Percent_Identity=28.8973384030418, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI15277342, Length=267, Percent_Identity=27.7153558052434, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=31.1475409836066, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=27.2373540856031, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=29.5, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=28.8702928870293, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=27.4131274131274, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI4758504, Length=223, Percent_Identity=31.390134529148, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI142976729, Length=221, Percent_Identity=30.316742081448, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=31.25, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI223718074, Length=214, Percent_Identity=27.1028037383178, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=28.735632183908, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4503301, Length=213, Percent_Identity=26.2910798122066, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI83715985, Length=223, Percent_Identity=30.0448430493274, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=28.2722513089005, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=28.3505154639175, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=25.6916996047431, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI226371731, Length=193, Percent_Identity=30.0518134715026, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4503817, Length=194, Percent_Identity=28.3505154639175, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI302344755, Length=103, Percent_Identity=34.9514563106796, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI109715829, Length=195, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=35.2490421455939, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=32.295719844358, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790717, Length=260, Percent_Identity=31.1538461538462, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788459, Length=259, Percent_Identity=33.2046332046332, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789208, Length=261, Percent_Identity=28.3524904214559, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=29.7297297297297, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=28.735632183908, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789378, Length=263, Percent_Identity=25.8555133079848, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=26.9230769230769, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=27.843137254902, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786701, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367365, Length=257, Percent_Identity=24.124513618677, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=27.3224043715847, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=264, Percent_Identity=29.1666666666667, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=265, Percent_Identity=27.9245283018868, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=265, Percent_Identity=28.6792452830189, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=270, Percent_Identity=25.9259259259259, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=201, Percent_Identity=29.3532338308458, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=30.2564102564103, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=275, Percent_Identity=26.5454545454545, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=213, Percent_Identity=30.0469483568075, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=27.734375, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=278, Percent_Identity=27.3381294964029, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=265, Percent_Identity=26.0377358490566, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=208, Percent_Identity=25.4807692307692, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=26.4822134387352, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=279, Percent_Identity=26.1648745519713, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=26.5, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=204, Percent_Identity=32.843137254902, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=24.7058823529412, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=205, Percent_Identity=31.7073170731707, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=28.643216080402, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=200, Percent_Identity=30.5, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=195, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=203, Percent_Identity=31.0344827586207, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=265, Percent_Identity=24.9056603773585, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=279, Percent_Identity=26.8817204301075, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=274, Percent_Identity=25.5474452554745, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=28.7822878228782, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=241, Percent_Identity=29.8755186721992, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=28.4974093264249, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=176, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644339, Length=269, Percent_Identity=33.0855018587361, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=29.2307692307692, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI18859837, Length=202, Percent_Identity=33.6633663366337, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI28571526, Length=262, Percent_Identity=30.9160305343511, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=27.6923076923077, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=30.7392996108949, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24643142, Length=264, Percent_Identity=26.5151515151515, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=26.1538461538462, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24639444, Length=261, Percent_Identity=25.2873563218391, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571387, Length=212, Percent_Identity=29.2452830188679, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=31.4432989690722, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=31.4432989690722, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI281364892, Length=175, Percent_Identity=28, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641232, Length=227, Percent_Identity=28.1938325991189, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281364494, Length=243, Percent_Identity=28.8065843621399, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356301, Length=198, Percent_Identity=25.7575757575758, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24649181, Length=176, Percent_Identity=28.4090909090909, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737361, Length=205, Percent_Identity=26.3414634146341, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355631, Length=179, Percent_Identity=27.9329608938547, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24641388, Length=210, Percent_Identity=28.0952380952381, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24640442, Length=198, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644337, Length=262, Percent_Identity=28.6259541984733, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=29.4736842105263, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=29.4736842105263, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27674; Mature: 27543

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNLKGKTAVVTGSTSGIGLAIARGFASAGANIVLNGFGAPDDIEKERASIESEFKVKA
CCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCEEEEE
VHSPADMSKPAEIAGMIALGESTFGSVDVLVNNAGIQFVSPVEDFPPEKWEQIIAINLSS
ECCCCCCCCCHHHEEEEEECCCCCCCEEEEEECCCCEEECCHHHCCHHHHCEEEEEEECH
AFYGIHAAVPGMKKRGWGRIINTASAHSLVASPFKSAYVSAKHGIAGLTKTVALELATFK
HHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEEEE
ITCNCISPGYVWTPLVEKQIPDTMKARNLTKEQVIHDVLLAAQPTKEFVTVDQVAALALF
EEEEEECCCEEECCHHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LCSDEAAQITGTNLSIDGGWTAE
HCCCCCCEEECCEEEECCCCCCC
>Mature Secondary Structure 
TTNLKGKTAVVTGSTSGIGLAIARGFASAGANIVLNGFGAPDDIEKERASIESEFKVKA
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCEEEEE
VHSPADMSKPAEIAGMIALGESTFGSVDVLVNNAGIQFVSPVEDFPPEKWEQIIAINLSS
ECCCCCCCCCHHHEEEEEECCCCCCCEEEEEECCCCEEECCHHHCCHHHHCEEEEEEECH
AFYGIHAAVPGMKKRGWGRIINTASAHSLVASPFKSAYVSAKHGIAGLTKTVALELATFK
HHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEEEE
ITCNCISPGYVWTPLVEKQIPDTMKARNLTKEQVIHDVLLAAQPTKEFVTVDQVAALALF
EEEEEECCCEEECCHHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LCSDEAAQITGTNLSIDGGWTAE
HCCCCCCEEECCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]