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The map label for this gene is yfhM [H]

Identifier: 146338034

GI number: 146338034

Start: 989669

End: 990739

Strand: Reverse

Name: yfhM [H]

Synonym: BRADO0927

Alternate gene names: 146338034

Gene position: 990739-989669 (Counterclockwise)

Preceding gene: 146338035

Following gene: 146338033

Centisome position: 13.29

GC content: 65.92

Gene sequence:

>1071_bases
ATGCATGTGCTCGAGGCCGGCTTCGAAACACCCGGGCGCCCCTGCGTGCTGCTGCTGCACGGCTTCCCCGAGCTCGCCTA
TAGCTGGCGCAAGGTGATGCCGGCGCTGGCGGCGGCGGGCTATCACGTGCTGGCGCCGGACCAGCGCGGCTATGGCCGCA
CCACCGGCTGGAACGCCGACTATGACGGCGACCTTGCGCCGTTCCGCTTCACCAACCTGGTGCGCGACGCGCTCGGCGTG
GTCTATGCCTTCGGTCATCGCCATGTCGCGGCGGTCGTCGGCCACGACTTCGGCAGCCCGGTCGCGGCGTGGTGCGCGGT
CATCCGGCCCGATGTGTTTCGATCGGTGGTGATGATGAGCGCACCGTTTCCGGGACCACCGGCCGCGCCGTTCGGCATCG
CCGACCATCCGCTCGCGCCGCCCGATGATCCCGTGCATCGCGAGCTGGCCACGCTGCCGCGGCCGCGCAAGCACTATCAA
TGGCACTACTCGACACCCGAGGCGAACGCGGACATGCATCGCGCGCCGCAGGGCCTGCATGCGTTCCTGCGCGCCTACTA
CCACCACAAGAGCGCCGACTGGTCGGGCAACCAGCCGTATCCGCTGCAATCATGGACCGCGGGCGAACTCGCCAAGCTGC
CGACCTACTACGTGATGGACCTCGACAAGACGATGGGCGAGACGGTCGCCGACGTCATGCCCGACGCGGCAACGATTGCC
GCCAATCGCTGGCTGCCGGATCATGAACTCGCGGTCTACACGGCCGAATATGAACGAACCGGCTTCCAGGGCGGCCTGCA
ATGGTACCGCTGCGGCACGTCGGGCCTGTTCGACGCGGAATTGCAGACCTGGTCGGACCGCACCATCGACGTTCCGTCTG
CATTCATCTCCGGCCTGCAAGACTGGGGCATCTACCAACGGCCCGGCGTGTTCGAAGCGATGCAGTCCCGAGTGTGCACC
AACATGATCCTGTGCGAGCTGATCGATCGCGCCGGTCATTGGGTGCAGCAGGAGCAACATGACCATGTCAATGAGCTCCT
GTTCACGTTCCTGAACAAATCGACAGCCTGA

Upstream 100 bases:

>100_bases
GGCCGCGATGACCTCTTCTTTTCCACTTCCAGCTCTTCCCCCGTTGCCTCTCCCACCCTCCATCCGCTCGCGCTATGTCG
ATGGCATCAACGGCTTGCGG

Downstream 100 bases:

>100_bases
TTTCGGACGCCGTTCCGACGTATTAGGCGAATCGAGGAACGAACATTCGGGGTTGACGTTTTTGCATCCGGGCGATGCGC
ATCAGGAGACGTTTTATGGA

Product: putative epoxide hydrolase

Products: glycol

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MHVLEAGFETPGRPCVLLLHGFPELAYSWRKVMPALAAAGYHVLAPDQRGYGRTTGWNADYDGDLAPFRFTNLVRDALGV
VYAFGHRHVAAVVGHDFGSPVAAWCAVIRPDVFRSVVMMSAPFPGPPAAPFGIADHPLAPPDDPVHRELATLPRPRKHYQ
WHYSTPEANADMHRAPQGLHAFLRAYYHHKSADWSGNQPYPLQSWTAGELAKLPTYYVMDLDKTMGETVADVMPDAATIA
ANRWLPDHELAVYTAEYERTGFQGGLQWYRCGTSGLFDAELQTWSDRTIDVPSAFISGLQDWGIYQRPGVFEAMQSRVCT
NMILCELIDRAGHWVQQEQHDHVNELLFTFLNKSTA

Sequences:

>Translated_356_residues
MHVLEAGFETPGRPCVLLLHGFPELAYSWRKVMPALAAAGYHVLAPDQRGYGRTTGWNADYDGDLAPFRFTNLVRDALGV
VYAFGHRHVAAVVGHDFGSPVAAWCAVIRPDVFRSVVMMSAPFPGPPAAPFGIADHPLAPPDDPVHRELATLPRPRKHYQ
WHYSTPEANADMHRAPQGLHAFLRAYYHHKSADWSGNQPYPLQSWTAGELAKLPTYYVMDLDKTMGETVADVMPDAATIA
ANRWLPDHELAVYTAEYERTGFQGGLQWYRCGTSGLFDAELQTWSDRTIDVPSAFISGLQDWGIYQRPGVFEAMQSRVCT
NMILCELIDRAGHWVQQEQHDHVNELLFTFLNKSTA
>Mature_356_residues
MHVLEAGFETPGRPCVLLLHGFPELAYSWRKVMPALAAAGYHVLAPDQRGYGRTTGWNADYDGDLAPFRFTNLVRDALGV
VYAFGHRHVAAVVGHDFGSPVAAWCAVIRPDVFRSVVMMSAPFPGPPAAPFGIADHPLAPPDDPVHRELATLPRPRKHYQ
WHYSTPEANADMHRAPQGLHAFLRAYYHHKSADWSGNQPYPLQSWTAGELAKLPTYYVMDLDKTMGETVADVMPDAATIA
ANRWLPDHELAVYTAEYERTGFQGGLQWYRCGTSGLFDAELQTWSDRTIDVPSAFISGLQDWGIYQRPGVFEAMQSRVCT
NMILCELIDRAGHWVQQEQHDHVNELLFTFLNKSTA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=362, Percent_Identity=23.2044198895028, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.3.2.3

Molecular weight: Translated: 39831; Mature: 39831

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVLEAGFETPGRPCVLLLHGFPELAYSWRKVMPALAAAGYHVLAPDQRGYGRTTGWNAD
CCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCC
YDGDLAPFRFTNLVRDALGVVYAFGHRHVAAVVGHDFGSPVAAWCAVIRPDVFRSVVMMS
CCCCCCHHHHHHHHHHHHHHHHHHCCHHEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHC
APFPGPPAAPFGIADHPLAPPDDPVHRELATLPRPRKHYQWHYSTPEANADMHRAPQGLH
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHCHHHHH
AFLRAYYHHKSADWSGNQPYPLQSWTAGELAKLPTYYVMDLDKTMGETVADVMPDAATIA
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCEEEEEECHHHHHHHHHHHCCCHHHHH
ANRWLPDHELAVYTAEYERTGFQGGLQWYRCGTSGLFDAELQTWSDRTIDVPSAFISGLQ
HHCCCCCCCEEEEEEHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCCEECCHHHHHHHH
DWGIYQRPGVFEAMQSRVCTNMILCELIDRAGHWVQQEQHDHVNELLFTFLNKSTA
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHVLEAGFETPGRPCVLLLHGFPELAYSWRKVMPALAAAGYHVLAPDQRGYGRTTGWNAD
CCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCC
YDGDLAPFRFTNLVRDALGVVYAFGHRHVAAVVGHDFGSPVAAWCAVIRPDVFRSVVMMS
CCCCCCHHHHHHHHHHHHHHHHHHCCHHEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHC
APFPGPPAAPFGIADHPLAPPDDPVHRELATLPRPRKHYQWHYSTPEANADMHRAPQGLH
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHCHHHHH
AFLRAYYHHKSADWSGNQPYPLQSWTAGELAKLPTYYVMDLDKTMGETVADVMPDAATIA
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCEEEEEECHHHHHHHHHHHCCCHHHHH
ANRWLPDHELAVYTAEYERTGFQGGLQWYRCGTSGLFDAELQTWSDRTIDVPSAFISGLQ
HHCCCCCCCEEEEEEHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCCEECCHHHHHHHH
DWGIYQRPGVFEAMQSRVCTNMILCELIDRAGHWVQQEQHDHVNELLFTFLNKSTA
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; epoxide

Specific reaction: H2O + an epoxide = a glycol

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]