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The map label for this gene is aidB [H]

Identifier: 146338027

GI number: 146338027

Start: 981385

End: 983169

Strand: Direct

Name: aidB [H]

Synonym: BRADO0920

Alternate gene names: 146338027

Gene position: 981385-983169 (Clockwise)

Preceding gene: 146338024

Following gene: 146338028

Centisome position: 13.16

GC content: 66.72

Gene sequence:

>1785_bases
ATGCATCAGTTCCTGAAGCGCGATGACGTGATGACCGGCGGGAAGAGGCCCGAGCTGCTGGCCCCGGATACCACCGGGCT
CAACTTCTACCGCGCCGATCCCGCGCTCTCCGACCTCCTGCGCATCCATCTGCCCGACGCGCTGTTTCGGCATCTCGTGC
CGCATCTCGACCGGCTCGGCGAGCTCGCCGGCGGCTATCTCGACGAATGCGCGCGGCTGGCCGACCGCCATGGACCGGTG
CTGCACCAGCGCGACCGCTTCGGCCGCGACGCCCAGTGGATCGAATATCACCCCGCCTATCGCGAGCTCGAGCGCGCCGC
CTTCGGCGAGTTCGGGATCCATGCGATGTCGATCCGCAAGGGCATTCTCGGTTGGCCGGCGAAATATCCCGTCGCCGCCA
AGCACGCCTTCACCTTCCTGTTCAATCAGGCGGAGTTCGGATTGGGCTGTCCGATCAACGTGACCGATGGCTGCGCCAAG
CTGCTGGCGAGCTTCGGGAGCCATGCGCTCAAGGCGAAGTACCTTGACGGCTTGACGCAGACCGACATGCGCAAGCTGAC
CCAGGGCGGCCAGTTCATGACCGAGAAGGAAGGCGGCTCCGACGTCGGCACGCTGACGACGGTCGCCGTGCCCGAGGGCG
ACCACTGGCGCCTGCATGGCGAGAAATGGTTCTGCTCCAATGCCGATGCCAAGGTGGTGATGCTGCTGGCGCGTCCCGAA
GGCGCCGAGCCCGGCACGCGCGGAGTCGGCCTGTTCCTGATGCCGCGCTTCCTCGATGACGGCACGCAGAACCACTATCG
AATCGTGCGCCTGAAGGACAAGCTCGGCACGCGTTCGATGGCGTCGGGTGAGATCAGGCTGGAAGGTGCCATCGCCTATG
CGGTCGGCCGGCTCGATCGCGGCTTCGTGCAGATGGCCGAGATGGTCAACTCCTCGCGACTCTCCAATGGTGTGAAGTCG
ACGGCGCTGATGCGGCGCGCCTGGCACGATGCGATCACGGTGGCGCGTAATCGCGTGGTGTTCGGACAGCGCATCGTGGA
CCTGCCGCTCGGCCGTCGCCAGCTGATGAAGATCCTGCTGCCGACCGAGCAGGCGCTGTCCATGAGCTTCCTCACCGCCG
ATGCGCTGGATCGCGCCGAGGCCGGCAGCCAGGACGCCGCGGCGCTGCTGCGCATCCTGACGCCGACTTTAAAATTTCGC
GCGACGCGCGATGCCCGCAAGGTCTGCGGCGATGCGTTGGAGATGCGTGGGGGTATCGGCTATGTCGAGGAGTTCGTCAC
GGCGCGGCTGTTGCGCGACGCGCATCTCGGCTCGATCTGGGAGGGCACCGGCAACATCGTCGCGCTGGATGCGCTGAAGC
GGGCCGTCGGCCGTCACGGCGCCGAGTCGGCGCTGGCAGCCGATCTGCATGCGCGGCTCGACGACAGCGCCGCCGTGCCG
CAGGCGTGGCGCGATCAGCTGCATCGCCTCGTCGATCGCGCCGTCGGCTTCGCACGCGAGGTCGCCGGCCGCGCCGACAA
TGAGGCCGAGTCGCGCCGTGCGACGAGTCTGCTGTATCACACGGCCAGCGTGGTCTCGCTCACTTGGGAAAGCGCGCGCA
TTTACGCCACGCGCGGCGACGCCCGGCGCCTGTTGTTGGCCAAGCTCGTCGTCGATCATCGGCTGATGCCGTCCGATCCA
TTCCAGCTCGCGGAAAACAACACGGATGATGCGATTGCAACGCTGCTCCTCGGCGAGCGCGATGCGACGATGCAGGAGGT
TGGCGAACTGATATCTGTGGCCTAG

Upstream 100 bases:

>100_bases
CCGGTTCGGCGCGAGCCGTGCCTGTTGTGTATCCGATCAGGCGCAACCTGTCGAAGAGTCCGTAAGAAGACTGGCGCAAA
CGAACGAGGGCTTACCGATC

Downstream 100 bases:

>100_bases
GCTGGCGAGGAGATATGAAGTGACATGCGGAACGAAGCTGACGCCACGCGCTCGGTGCACCCTCTCCCCTTGTGGGAGAG
GGTGGCTTTCATGCGCAGCA

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MHQFLKRDDVMTGGKRPELLAPDTTGLNFYRADPALSDLLRIHLPDALFRHLVPHLDRLGELAGGYLDECARLADRHGPV
LHQRDRFGRDAQWIEYHPAYRELERAAFGEFGIHAMSIRKGILGWPAKYPVAAKHAFTFLFNQAEFGLGCPINVTDGCAK
LLASFGSHALKAKYLDGLTQTDMRKLTQGGQFMTEKEGGSDVGTLTTVAVPEGDHWRLHGEKWFCSNADAKVVMLLARPE
GAEPGTRGVGLFLMPRFLDDGTQNHYRIVRLKDKLGTRSMASGEIRLEGAIAYAVGRLDRGFVQMAEMVNSSRLSNGVKS
TALMRRAWHDAITVARNRVVFGQRIVDLPLGRRQLMKILLPTEQALSMSFLTADALDRAEAGSQDAAALLRILTPTLKFR
ATRDARKVCGDALEMRGGIGYVEEFVTARLLRDAHLGSIWEGTGNIVALDALKRAVGRHGAESALAADLHARLDDSAAVP
QAWRDQLHRLVDRAVGFAREVAGRADNEAESRRATSLLYHTASVVSLTWESARIYATRGDARRLLLAKLVVDHRLMPSDP
FQLAENNTDDAIATLLLGERDATMQEVGELISVA

Sequences:

>Translated_594_residues
MHQFLKRDDVMTGGKRPELLAPDTTGLNFYRADPALSDLLRIHLPDALFRHLVPHLDRLGELAGGYLDECARLADRHGPV
LHQRDRFGRDAQWIEYHPAYRELERAAFGEFGIHAMSIRKGILGWPAKYPVAAKHAFTFLFNQAEFGLGCPINVTDGCAK
LLASFGSHALKAKYLDGLTQTDMRKLTQGGQFMTEKEGGSDVGTLTTVAVPEGDHWRLHGEKWFCSNADAKVVMLLARPE
GAEPGTRGVGLFLMPRFLDDGTQNHYRIVRLKDKLGTRSMASGEIRLEGAIAYAVGRLDRGFVQMAEMVNSSRLSNGVKS
TALMRRAWHDAITVARNRVVFGQRIVDLPLGRRQLMKILLPTEQALSMSFLTADALDRAEAGSQDAAALLRILTPTLKFR
ATRDARKVCGDALEMRGGIGYVEEFVTARLLRDAHLGSIWEGTGNIVALDALKRAVGRHGAESALAADLHARLDDSAAVP
QAWRDQLHRLVDRAVGFAREVAGRADNEAESRRATSLLYHTASVVSLTWESARIYATRGDARRLLLAKLVVDHRLMPSDP
FQLAENNTDDAIATLLLGERDATMQEVGELISVA
>Mature_594_residues
MHQFLKRDDVMTGGKRPELLAPDTTGLNFYRADPALSDLLRIHLPDALFRHLVPHLDRLGELAGGYLDECARLADRHGPV
LHQRDRFGRDAQWIEYHPAYRELERAAFGEFGIHAMSIRKGILGWPAKYPVAAKHAFTFLFNQAEFGLGCPINVTDGCAK
LLASFGSHALKAKYLDGLTQTDMRKLTQGGQFMTEKEGGSDVGTLTTVAVPEGDHWRLHGEKWFCSNADAKVVMLLARPE
GAEPGTRGVGLFLMPRFLDDGTQNHYRIVRLKDKLGTRSMASGEIRLEGAIAYAVGRLDRGFVQMAEMVNSSRLSNGVKS
TALMRRAWHDAITVARNRVVFGQRIVDLPLGRRQLMKILLPTEQALSMSFLTADALDRAEAGSQDAAALLRILTPTLKFR
ATRDARKVCGDALEMRGGIGYVEEFVTARLLRDAHLGSIWEGTGNIVALDALKRAVGRHGAESALAADLHARLDDSAAVP
QAWRDQLHRLVDRAVGFAREVAGRADNEAESRRATSLLYHTASVVSLTWESARIYATRGDARRLLLAKLVVDHRLMPSDP
FQLAENNTDDAIATLLLGERDATMQEVGELISVA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557235, Length=295, Percent_Identity=25.7627118644068, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI76496475, Length=295, Percent_Identity=25.7627118644068, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4501859, Length=289, Percent_Identity=25.2595155709343, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI226958412, Length=318, Percent_Identity=25.7861635220126, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI226958414, Length=318, Percent_Identity=25.7861635220126, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI7656849, Length=306, Percent_Identity=25.1633986928105, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4557233, Length=287, Percent_Identity=26.8292682926829, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI21361497, Length=307, Percent_Identity=26.0586319218241, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4501857, Length=261, Percent_Identity=24.5210727969349, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082384, Length=397, Percent_Identity=34.5088161209068, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI87081958, Length=260, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI86563383, Length=444, Percent_Identity=34.6846846846847, Blast_Score=225, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI86563381, Length=444, Percent_Identity=34.6846846846847, Blast_Score=225, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI17506239, Length=290, Percent_Identity=24.1379310344828, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=293, Percent_Identity=25.2559726962457, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=372, Percent_Identity=24.4623655913978, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=315, Percent_Identity=24.7619047619048, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=196, Percent_Identity=29.5918367346939, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=312, Percent_Identity=25, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=194, Percent_Identity=23.7113402061856, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551932, Length=304, Percent_Identity=26.6447368421053, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71990804, Length=209, Percent_Identity=24.8803827751196, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17505929, Length=304, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24666513, Length=290, Percent_Identity=25.8620689655172, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281363737, Length=267, Percent_Identity=26.9662921348315, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356377, Length=352, Percent_Identity=24.4318181818182, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21355753, Length=294, Percent_Identity=25.8503401360544, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24660351, Length=328, Percent_Identity=24.390243902439, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=21.8085106382979, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 65536; Mature: 65536

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQFLKRDDVMTGGKRPELLAPDTTGLNFYRADPALSDLLRIHLPDALFRHLVPHLDRLG
CCCHHHHCCCCCCCCCCCEECCCCCCCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHH
ELAGGYLDECARLADRHGPVLHQRDRFGRDAQWIEYHPAYRELERAAFGEFGIHAMSIRK
HHHCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEECHHHHHHHHHHHHHCCCHHHHHHH
GILGWPAKYPVAAKHAFTFLFNQAEFGLGCPINVTDGCAKLLASFGSHALKAKYLDGLTQ
HHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCH
TDMRKLTQGGQFMTEKEGGSDVGTLTTVAVPEGDHWRLHGEKWFCSNADAKVVMLLARPE
HHHHHHHCCCCEEECCCCCCCCCCEEEEEECCCCCEEECCCEEEECCCCCEEEEEEECCC
GAEPGTRGVGLFLMPRFLDDGTQNHYRIVRLKDKLGTRSMASGEIRLEGAIAYAVGRLDR
CCCCCCCCCCCEEEHHHHCCCCCCCEEEEEEHHHCCCCCCCCCCEEEEHHHHHHHHHHHH
GFVQMAEMVNSSRLSNGVKSTALMRRAWHDAITVARNRVVFGQRIVDLPLGRRQLMKILL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHC
PTEQALSMSFLTADALDRAEAGSQDAAALLRILTPTLKFRATRDARKVCGDALEMRGGIG
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCH
YVEEFVTARLLRDAHLGSIWEGTGNIVALDALKRAVGRHGAESALAADLHARLDDSAAVP
HHHHHHHHHHHHHHHCCCEECCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
QAWRDQLHRLVDRAVGFAREVAGRADNEAESRRATSLLYHTASVVSLTWESARIYATRGD
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCH
ARRLLLAKLVVDHRLMPSDPFQLAENNTDDAIATLLLGERDATMQEVGELISVA
HHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MHQFLKRDDVMTGGKRPELLAPDTTGLNFYRADPALSDLLRIHLPDALFRHLVPHLDRLG
CCCHHHHCCCCCCCCCCCEECCCCCCCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHH
ELAGGYLDECARLADRHGPVLHQRDRFGRDAQWIEYHPAYRELERAAFGEFGIHAMSIRK
HHHCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEECHHHHHHHHHHHHHCCCHHHHHHH
GILGWPAKYPVAAKHAFTFLFNQAEFGLGCPINVTDGCAKLLASFGSHALKAKYLDGLTQ
HHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCH
TDMRKLTQGGQFMTEKEGGSDVGTLTTVAVPEGDHWRLHGEKWFCSNADAKVVMLLARPE
HHHHHHHCCCCEEECCCCCCCCCCEEEEEECCCCCEEECCCEEEECCCCCEEEEEEECCC
GAEPGTRGVGLFLMPRFLDDGTQNHYRIVRLKDKLGTRSMASGEIRLEGAIAYAVGRLDR
CCCCCCCCCCCEEEHHHHCCCCCCCEEEEEEHHHCCCCCCCCCCEEEEHHHHHHHHHHHH
GFVQMAEMVNSSRLSNGVKSTALMRRAWHDAITVARNRVVFGQRIVDLPLGRRQLMKILL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHC
PTEQALSMSFLTADALDRAEAGSQDAAALLRILTPTLKFRATRDARKVCGDALEMRGGIG
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCH
YVEEFVTARLLRDAHLGSIWEGTGNIVALDALKRAVGRHGAESALAADLHARLDDSAAVP
HHHHHHHHHHHHHHHCCCEECCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
QAWRDQLHRLVDRAVGFAREVAGRADNEAESRRATSLLYHTASVVSLTWESARIYATRGD
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCH
ARRLLLAKLVVDHRLMPSDPFQLAENNTDDAIATLLLGERDATMQEVGELISVA
HHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]