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The map label for this gene is amiC [H]

Identifier: 146338005

GI number: 146338005

Start: 949547

End: 951022

Strand: Direct

Name: amiC [H]

Synonym: BRADO0898

Alternate gene names: 146338005

Gene position: 949547-951022 (Clockwise)

Preceding gene: 146338003

Following gene: 146338007

Centisome position: 12.73

GC content: 66.4

Gene sequence:

>1476_bases
ATGACTTTGGCGATGAGCTGGGACGAATGGGCCCGGCATGACGGCATGGCACTCGCAGCCCGCGTTCGCAACGGCGAACT
GACCGCGGCGGAGCTGGCGCAGCAGGCTGCCGAGGGCATCGCCAAGGTCGATCCGCAACTATCAGGCGTTGTGGAAGTCT
TCGCCGACGCGGTGGACGATCCGATCAAGGCCGGCGCGAATGCCGATGGCTCGTTCGCCGGCCTGCCGTTCCTGATGAAG
GATCTCGGACCGACCATGGCCGGGCGCCTGCAGGAGCAGGGCTCGCTCTACATGCGCGGCAACCGTCCGGCCGCAGACAC
GCACCTCACGAAAAAGATGCGCAGGGCCGGCCTCAATCTGATGGGCCGCACGACGACGCCGGAGTTTGGCGTCTGCAGCT
CGGCGGAAAATCCTGCGGTCTACGTCACGCGCAACCCGTGGGACACGGACTACACGACCTGCGGCTCCTCGGCGGGAAGC
GCCGCGATGGTCGCGGCCGGCGTAGTGCCGATCGCGCATGCGACCGACGGCGGGGGTTCGATCCGGATTCCCGCAGGCGT
CAACGGCAACATCGGTTTGAAAGTTTCGCGCGGCGTGTTCTCGATCGCGCCGCATCTGTCGGATCTCTCCGGCCTGGTCT
CGATCCAAGGCTGCCAGTCGCGCAGCGTGCGCGACACCGCCGCCTTCGTCGACCATTGCCGGGGCGGCGCGCCGGGCGAG
TTCATGCCGTATTGGACTGCTCCGGAGCCCTATGTCGAGCTGATCAAGCGCGATCCCGGCAGGCTCAGGATCGCGCTGTC
GCATCAATGGGGCGACTATCGCGCGACGCCGCACATCGCGTCCGAGCTTCAGCGCGTCGGAAAATTCCTCGAAGGTCTCG
GTCATCACGTCGGCTATGCTCTGCCGGACGTCGACTATCGCGCGGCGTTCGCGGCGCAGACCACCTGCTACATCTCGAAC
TTCGCCATGGTCATCAACAACCTGCTGGCGCAGCGGAAGCTCGAGCGGCCGCCGGCCGAACTGATCGAACCGATCAACAT
TCGCATCTGGGAGGCCGGCCGCGGCACCAGCTTCGCCGAGCGCGCGGCAATGCAGGCCGTGTTCAACACCACGTCGCGCG
CCTTCGGCGCCTTCTTCGAGGAGTGGGACATCATCCTGACGCCGATCACGGCGCTGCCGACCCCGAAGATCGGCACCACG
GAATATCTGACGATCAGCGACAATCCGGACGTGCTCGACTGGTTCGGCAATCTCTGGCGCAACTTCGCCTTCACGCCGCT
CGCCAATCTCTGCGGCATCCCGGCGGTCTCGCTGCCGCTCGCCACCAACGAGCACGGCCTGCCGCTCGGCATCCAGGCGA
TCGGCAAGCAGGCCGATGACGGCCTGTTGCTGCAGCTGGCTGCTCAGATCGAGCGCGCCATCGACGGTCGATGGAATGGC
GGTGCCACGCCGGCGGTCCACGTCACCAAGGGGTGA

Upstream 100 bases:

>100_bases
TGATTGACTCGCTGCCTTCGCAAACTAAGGTTCGCGCTAGAACAAGACAGCGCAGGATCGTCGTATCGATCGGCGGTCAG
CGCGAAGGATCGGACGGCAA

Downstream 100 bases:

>100_bases
CGGCGACCGCGGGCCGGCGGTTAATCGCGCGAACGGCTGCTCACCTCGGCCATCCACGGCGAGTCCTGCAGCGCGGCAAT
GCCGATGTCGTCGAGCACGA

Product: putative amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MTLAMSWDEWARHDGMALAARVRNGELTAAELAQQAAEGIAKVDPQLSGVVEVFADAVDDPIKAGANADGSFAGLPFLMK
DLGPTMAGRLQEQGSLYMRGNRPAADTHLTKKMRRAGLNLMGRTTTPEFGVCSSAENPAVYVTRNPWDTDYTTCGSSAGS
AAMVAAGVVPIAHATDGGGSIRIPAGVNGNIGLKVSRGVFSIAPHLSDLSGLVSIQGCQSRSVRDTAAFVDHCRGGAPGE
FMPYWTAPEPYVELIKRDPGRLRIALSHQWGDYRATPHIASELQRVGKFLEGLGHHVGYALPDVDYRAAFAAQTTCYISN
FAMVINNLLAQRKLERPPAELIEPINIRIWEAGRGTSFAERAAMQAVFNTTSRAFGAFFEEWDIILTPITALPTPKIGTT
EYLTISDNPDVLDWFGNLWRNFAFTPLANLCGIPAVSLPLATNEHGLPLGIQAIGKQADDGLLLQLAAQIERAIDGRWNG
GATPAVHVTKG

Sequences:

>Translated_491_residues
MTLAMSWDEWARHDGMALAARVRNGELTAAELAQQAAEGIAKVDPQLSGVVEVFADAVDDPIKAGANADGSFAGLPFLMK
DLGPTMAGRLQEQGSLYMRGNRPAADTHLTKKMRRAGLNLMGRTTTPEFGVCSSAENPAVYVTRNPWDTDYTTCGSSAGS
AAMVAAGVVPIAHATDGGGSIRIPAGVNGNIGLKVSRGVFSIAPHLSDLSGLVSIQGCQSRSVRDTAAFVDHCRGGAPGE
FMPYWTAPEPYVELIKRDPGRLRIALSHQWGDYRATPHIASELQRVGKFLEGLGHHVGYALPDVDYRAAFAAQTTCYISN
FAMVINNLLAQRKLERPPAELIEPINIRIWEAGRGTSFAERAAMQAVFNTTSRAFGAFFEEWDIILTPITALPTPKIGTT
EYLTISDNPDVLDWFGNLWRNFAFTPLANLCGIPAVSLPLATNEHGLPLGIQAIGKQADDGLLLQLAAQIERAIDGRWNG
GATPAVHVTKG
>Mature_490_residues
TLAMSWDEWARHDGMALAARVRNGELTAAELAQQAAEGIAKVDPQLSGVVEVFADAVDDPIKAGANADGSFAGLPFLMKD
LGPTMAGRLQEQGSLYMRGNRPAADTHLTKKMRRAGLNLMGRTTTPEFGVCSSAENPAVYVTRNPWDTDYTTCGSSAGSA
AMVAAGVVPIAHATDGGGSIRIPAGVNGNIGLKVSRGVFSIAPHLSDLSGLVSIQGCQSRSVRDTAAFVDHCRGGAPGEF
MPYWTAPEPYVELIKRDPGRLRIALSHQWGDYRATPHIASELQRVGKFLEGLGHHVGYALPDVDYRAAFAAQTTCYISNF
AMVINNLLAQRKLERPPAELIEPINIRIWEAGRGTSFAERAAMQAVFNTTSRAFGAFFEEWDIILTPITALPTPKIGTTE
YLTISDNPDVLDWFGNLWRNFAFTPLANLCGIPAVSLPLATNEHGLPLGIQAIGKQADDGLLLQLAAQIERAIDGRWNGG
ATPAVHVTKG

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=515, Percent_Identity=24.8543689320388, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI195972892, Length=198, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538252, Length=488, Percent_Identity=21.7213114754098, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319685, Length=382, Percent_Identity=26.4397905759162, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356731, Length=494, Percent_Identity=25.1012145748988, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI161078093, Length=500, Percent_Identity=24.8, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648113, Length=440, Percent_Identity=25.4545454545455, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24644968, Length=514, Percent_Identity=22.7626459143969, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24652985, Length=201, Percent_Identity=29.8507462686567, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922090, Length=201, Percent_Identity=29.8507462686567, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24652981, Length=201, Percent_Identity=29.8507462686567, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24652983, Length=201, Percent_Identity=29.8507462686567, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550774, Length=190, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648435, Length=201, Percent_Identity=25.8706467661692, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648437, Length=201, Percent_Identity=25.8706467661692, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 52588; Mature: 52457

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAMSWDEWARHDGMALAARVRNGELTAAELAQQAAEGIAKVDPQLSGVVEVFADAVDD
CEEECCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
PIKAGANADGSFAGLPFLMKDLGPTMAGRLQEQGSLYMRGNRPAADTHLTKKMRRAGLNL
HHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCE
MGRTTTPEFGVCSSAENPAVYVTRNPWDTDYTTCGSSAGSAAMVAAGVVPIAHATDGGGS
EECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHCCEEEEEECCCCCE
IRIPAGVNGNIGLKVSRGVFSIAPHLSDLSGLVSIQGCQSRSVRDTAAFVDHCRGGAPGE
EEECCCCCCCEEEEECCCCHHHCCCHHHHHHHEEECCCCCCCHHHHHHHHHHHCCCCCCC
FMPYWTAPEPYVELIKRDPGRLRIALSHQWGDYRATPHIASELQRVGKFLEGLGHHVGYA
CCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
LPDVDYRAAFAAQTTCYISNFAMVINNLLAQRKLERPPAELIEPINIRIWEAGRGTSFAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCCHHHH
RAAMQAVFNTTSRAFGAFFEEWDIILTPITALPTPKIGTTEYLTISDNPDVLDWFGNLWR
HHHHHHHHHHHHHHHHHHHHCCCEEEECHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHH
NFAFTPLANLCGIPAVSLPLATNEHGLPLGIQAIGKQADDGLLLQLAAQIERAIDGRWNG
HCCCCHHHHHHCCCCEEECCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
GATPAVHVTKG
CCCCEEEEECC
>Mature Secondary Structure 
TLAMSWDEWARHDGMALAARVRNGELTAAELAQQAAEGIAKVDPQLSGVVEVFADAVDD
EEECCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
PIKAGANADGSFAGLPFLMKDLGPTMAGRLQEQGSLYMRGNRPAADTHLTKKMRRAGLNL
HHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCE
MGRTTTPEFGVCSSAENPAVYVTRNPWDTDYTTCGSSAGSAAMVAAGVVPIAHATDGGGS
EECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHCCEEEEEECCCCCE
IRIPAGVNGNIGLKVSRGVFSIAPHLSDLSGLVSIQGCQSRSVRDTAAFVDHCRGGAPGE
EEECCCCCCCEEEEECCCCHHHCCCHHHHHHHEEECCCCCCCHHHHHHHHHHHCCCCCCC
FMPYWTAPEPYVELIKRDPGRLRIALSHQWGDYRATPHIASELQRVGKFLEGLGHHVGYA
CCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
LPDVDYRAAFAAQTTCYISNFAMVINNLLAQRKLERPPAELIEPINIRIWEAGRGTSFAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCCHHHH
RAAMQAVFNTTSRAFGAFFEEWDIILTPITALPTPKIGTTEYLTISDNPDVLDWFGNLWR
HHHHHHHHHHHHHHHHHHHHCCCEEEECHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHH
NFAFTPLANLCGIPAVSLPLATNEHGLPLGIQAIGKQADDGLLLQLAAQIERAIDGRWNG
HCCCCHHHHHHCCCCEEECCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
GATPAVHVTKG
CCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]