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The map label for this gene is dppA [H]

Identifier: 146338001

GI number: 146338001

Start: 944267

End: 945808

Strand: Reverse

Name: dppA [H]

Synonym: BRADO0894

Alternate gene names: 146338001

Gene position: 945808-944267 (Counterclockwise)

Preceding gene: 146338002

Following gene: 146338000

Centisome position: 12.68

GC content: 63.55

Gene sequence:

>1542_bases
ATGCGTGACCATCAGATCTCTCGCCGTACGATGTTGCAGCTCGCCGGCGCGGCTGCTCTGCCGCTCGCCACCGGCCTGCC
GCTGCGTCCCGCCAGCGCCGCCTCCGGCACCCTGACCATCGCCTACAACGTCAATTTGCCGTCGTTCGACCCGACCGTCG
GCGTCTCCGCCGTCAATCCCACGATCCAGTCGATCTACCAGGCGATCTTCGATCCCTATATCGGCCAGGCCGCCGATCTC
TCGTTCACGCCGGGGCTGCTGACGAAGTGGGGCTGGAACGAGGACCGCACCAAGGTCACGATGGAGCTGCGCTCCGACGC
GACCTGGCATGACGGCTCCAAGGTGACGCCGGAGGACGTGGTGTGGTCGCTGACCCGTGCCGCCGATCCGAAGGGTGGCA
ACCCGATCCAGTTCGTGTGGTCCAAGATCAACAATTTCAAGATCGATGGCCAGACCATCACGGCCGATGTCGTCGAGTTC
GAGCCGGTGCTGTTCAAATGGATGGCGTTCCTCACCGGCTACGTGCTGCCGAAAGCCTACTACGAAAAGGTCGGCCCCGA
GGGGTTCGAGAAGGCGCCGATCGGCTCGGGCCCGTACAAGGTCGATGCGTTCGAGCGCAACGCGTTCCTGCGGCTGAAGG
CGCATGCCGGCTATTGGGGGCCGAAGCCGGCGTTCGAAACCGTGGTCTTCAAGTTTGTCACCGATCCGACCAGCCGCGTC
GCCGAGATCGAATCCGGCGGCTCCGACATCACCTTCGAGATTCCCTATGAGGAATTCGATCGTCTGAAGGCCAAGCCGAA
CCTCGCAGGCTTGACGCAGCCGATCTCCGACATCGGCATGATCTTCCTGACCGACATCGATCCGATGCTCGACCGCAATG
TGCGCCTCGCCGCCAATCACGCCATCGACAAGAAGGCGATCGTCGAGAAGCTGCTGCGCGGCTATGGCGTGCCGATCGAT
ACGTTGGAAGCGCCGGGCTACGCCGCCTTCGATCCATCGATCAAGGTCGCCTATGATCCGGAGCTCGCCAAGAGCCTGCT
CGCCAAGAGCGGCTACTCGACGTCCAAGCCGGTCAAGTTCACGATCCAGACCACGCGCGGCTTCAAGCCGAAGGACTACG
AGATGGTGCAGGCCATCGCCGGCATGTGGCGCAAGGTCGGCATCGAGGCCAATATCGAGGTCTACGAGATCGCCCAGCAT
TTCGAGCTGCGCGCGCGTCACGCGCTGGCGCCGGCCGCGTTCTACAATTGGGGCAATGCGATCGGCGATCCCACGACCTC
GACGGGCTTTGCGATGTTCGGCCCGTCGCCGCATTCGGCCTGGAAGGGCAAGGACCTGATCGAGCGCATCGGGCCCTTGT
GGGGCGAGAAGGACGAGGCCAAGCGGATCGCCGGCTGGAAGGCGGTCGACAAGTACATCGCCGAGGAAGGCGAGGTGATT
CCGCTGCTGCAATACGTCCAGCCGATCGTACACAAGAAGGGGCTGAAGGTGGTGCCGCAGGCCAACGGCATGATCCTGCC
GCAGCTCGTGACTCAGGGCTGA

Upstream 100 bases:

>100_bases
CGCCGCACTGATCATCAGGCGGGGATGGGGCCGGCAGGGGCGCCATTCCCCAATCTGTCATTTGCTCACTCATCGTTCGC
TCATTTGGAGTTGCATCACC

Downstream 100 bases:

>100_bases
GACGGAGCAGAGCGATGCGCTGGAGCGCCCTACTCAAGCGCCTCGCTCTGATCCCGCCGACCCTGCTCGGCGTCGGCGCC
ATCGTGTTCGTGCTGTTGCG

Product: peptide ABC transporter substrate-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MRDHQISRRTMLQLAGAAALPLATGLPLRPASAASGTLTIAYNVNLPSFDPTVGVSAVNPTIQSIYQAIFDPYIGQAADL
SFTPGLLTKWGWNEDRTKVTMELRSDATWHDGSKVTPEDVVWSLTRAADPKGGNPIQFVWSKINNFKIDGQTITADVVEF
EPVLFKWMAFLTGYVLPKAYYEKVGPEGFEKAPIGSGPYKVDAFERNAFLRLKAHAGYWGPKPAFETVVFKFVTDPTSRV
AEIESGGSDITFEIPYEEFDRLKAKPNLAGLTQPISDIGMIFLTDIDPMLDRNVRLAANHAIDKKAIVEKLLRGYGVPID
TLEAPGYAAFDPSIKVAYDPELAKSLLAKSGYSTSKPVKFTIQTTRGFKPKDYEMVQAIAGMWRKVGIEANIEVYEIAQH
FELRARHALAPAAFYNWGNAIGDPTTSTGFAMFGPSPHSAWKGKDLIERIGPLWGEKDEAKRIAGWKAVDKYIAEEGEVI
PLLQYVQPIVHKKGLKVVPQANGMILPQLVTQG

Sequences:

>Translated_513_residues
MRDHQISRRTMLQLAGAAALPLATGLPLRPASAASGTLTIAYNVNLPSFDPTVGVSAVNPTIQSIYQAIFDPYIGQAADL
SFTPGLLTKWGWNEDRTKVTMELRSDATWHDGSKVTPEDVVWSLTRAADPKGGNPIQFVWSKINNFKIDGQTITADVVEF
EPVLFKWMAFLTGYVLPKAYYEKVGPEGFEKAPIGSGPYKVDAFERNAFLRLKAHAGYWGPKPAFETVVFKFVTDPTSRV
AEIESGGSDITFEIPYEEFDRLKAKPNLAGLTQPISDIGMIFLTDIDPMLDRNVRLAANHAIDKKAIVEKLLRGYGVPID
TLEAPGYAAFDPSIKVAYDPELAKSLLAKSGYSTSKPVKFTIQTTRGFKPKDYEMVQAIAGMWRKVGIEANIEVYEIAQH
FELRARHALAPAAFYNWGNAIGDPTTSTGFAMFGPSPHSAWKGKDLIERIGPLWGEKDEAKRIAGWKAVDKYIAEEGEVI
PLLQYVQPIVHKKGLKVVPQANGMILPQLVTQG
>Mature_513_residues
MRDHQISRRTMLQLAGAAALPLATGLPLRPASAASGTLTIAYNVNLPSFDPTVGVSAVNPTIQSIYQAIFDPYIGQAADL
SFTPGLLTKWGWNEDRTKVTMELRSDATWHDGSKVTPEDVVWSLTRAADPKGGNPIQFVWSKINNFKIDGQTITADVVEF
EPVLFKWMAFLTGYVLPKAYYEKVGPEGFEKAPIGSGPYKVDAFERNAFLRLKAHAGYWGPKPAFETVVFKFVTDPTSRV
AEIESGGSDITFEIPYEEFDRLKAKPNLAGLTQPISDIGMIFLTDIDPMLDRNVRLAANHAIDKKAIVEKLLRGYGVPID
TLEAPGYAAFDPSIKVAYDPELAKSLLAKSGYSTSKPVKFTIQTTRGFKPKDYEMVQAIAGMWRKVGIEANIEVYEIAQH
FELRARHALAPAAFYNWGNAIGDPTTSTGFAMFGPSPHSAWKGKDLIERIGPLWGEKDEAKRIAGWKAVDKYIAEEGEVI
PLLQYVQPIVHKKGLKVVPQANGMILPQLVTQG

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=496, Percent_Identity=26.008064516129, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1789887, Length=525, Percent_Identity=24.3809523809524, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787052, Length=502, Percent_Identity=24.3027888446215, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87081878, Length=550, Percent_Identity=26.1818181818182, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787495, Length=524, Percent_Identity=23.6641221374046, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787762, Length=497, Percent_Identity=21.7303822937626, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787551, Length=495, Percent_Identity=19.3939393939394, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 56505; Mature: 56505

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDHQISRRTMLQLAGAAALPLATGLPLRPASAASGTLTIAYNVNLPSFDPTVGVSAVNP
CCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCH
TIQSIYQAIFDPYIGQAADLSFTPGLLTKWGWNEDRTKVTMELRSDATWHDGSKVTPEDV
HHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHH
VWSLTRAADPKGGNPIQFVWSKINNFKIDGQTITADVVEFEPVLFKWMAFLTGYVLPKAY
HHHHHHCCCCCCCCHHHHHHHHHCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
YEKVGPEGFEKAPIGSGPYKVDAFERNAFLRLKAHAGYWGPKPAFETVVFKFVTDPTSRV
HHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHH
AEIESGGSDITFEIPYEEFDRLKAKPNLAGLTQPISDIGMIFLTDIDPMLDRNVRLAANH
HHHCCCCCEEEEECCHHHHHHHCCCCCCCCCCCCHHHCCEEEEECCCHHHCCCEEEEHHH
AIDKKAIVEKLLRGYGVPIDTLEAPGYAAFDPSIKVAYDPELAKSLLAKSGYSTSKPVKF
CCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEECHHHHHHHHHHCCCCCCCCEEE
TIQTTRGFKPKDYEMVQAIAGMWRKVGIEANIEVYEIAQHFELRARHALAPAAFYNWGNA
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCC
IGDPTTSTGFAMFGPSPHSAWKGKDLIERIGPLWGEKDEAKRIAGWKAVDKYIAEEGEVI
CCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
PLLQYVQPIVHKKGLKVVPQANGMILPQLVTQG
HHHHHHHHHHHCCCCEEEECCCCEEHHHHHCCC
>Mature Secondary Structure
MRDHQISRRTMLQLAGAAALPLATGLPLRPASAASGTLTIAYNVNLPSFDPTVGVSAVNP
CCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCH
TIQSIYQAIFDPYIGQAADLSFTPGLLTKWGWNEDRTKVTMELRSDATWHDGSKVTPEDV
HHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHH
VWSLTRAADPKGGNPIQFVWSKINNFKIDGQTITADVVEFEPVLFKWMAFLTGYVLPKAY
HHHHHHCCCCCCCCHHHHHHHHHCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
YEKVGPEGFEKAPIGSGPYKVDAFERNAFLRLKAHAGYWGPKPAFETVVFKFVTDPTSRV
HHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHH
AEIESGGSDITFEIPYEEFDRLKAKPNLAGLTQPISDIGMIFLTDIDPMLDRNVRLAANH
HHHCCCCCEEEEECCHHHHHHHCCCCCCCCCCCCHHHCCEEEEECCCHHHCCCEEEEHHH
AIDKKAIVEKLLRGYGVPIDTLEAPGYAAFDPSIKVAYDPELAKSLLAKSGYSTSKPVKF
CCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEECHHHHHHHHHHCCCCCCCCEEE
TIQTTRGFKPKDYEMVQAIAGMWRKVGIEANIEVYEIAQHFELRARHALAPAAFYNWGNA
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCC
IGDPTTSTGFAMFGPSPHSAWKGKDLIERIGPLWGEKDEAKRIAGWKAVDKYIAEEGEVI
CCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
PLLQYVQPIVHKKGLKVVPQANGMILPQLVTQG
HHHHHHHHHHHCCCCEEEECCCCEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]