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The map label for this gene is guaA [H]

Identifier: 146337962

GI number: 146337962

Start: 907299

End: 908129

Strand: Direct

Name: guaA [H]

Synonym: BRADO0854

Alternate gene names: 146337962

Gene position: 907299-908129 (Clockwise)

Preceding gene: 146337961

Following gene: 146337965

Centisome position: 12.17

GC content: 65.7

Gene sequence:

>831_bases
GTGTTGAAGCTGCTCGTGCTCGAAGGCAATTCGCTCGCGGGCCGGAGTCGCTGGGCGGAGATTGCCGGGCATACTCCATC
GGAGAGCTATGCCGACGTGCTGCGTGCGTTGGCGCCTGATGCAGTGATCGACATCGCGACGCCCGCCGACGCCGATGCGC
GGCTGCCGCAGCCGATCGACGCCTATGAAGGCATCGTCATCACCGGATCGGCGCTGAACATCTATCAGCGCGAGCCCGAG
TCCCTGCGTCAGATCGAGCTGCTGCGCATGATCTTCGCGCAGGGCGTGCCGATGTTCGGCTCCTGTTGGGGACTGCAGCT
GGCGACGGTCGCTGCCGGCGGCGAGGTGTCGCTCAATCCGGCCGGCCGCGAAGTCGGCTTCGCACGCAAGGTCGTACTGA
CGGAGGCGGGTCGCCGTCATCCGCTGCATGAAATGCGTGGCGAGGTGTTCGATGCGCCGGCGATCCACAGCGACATCGTG
ACCAAGCTGCCGCCGGATGCAACGGTGACGGCGCGCAACGCCATGAGCGAGGTGCAGGCGGCGGAAATCAGGAGCGGCCA
CGGTCGTTTCTGGGGTGTACAATATCACCCGGAGTTCAGCCTGCAGGACGTGGCCTGGGTCATCCGACGCATCGGCCAGC
CGCTGGTCGATGAGGGATTTTTCGCCGATGCGATCGAACTCGAGCGCTATGCCGCCGATCTCGCCTCGCTGCATCAGGAT
CGGGCGCGGCGCGATCTGCTCTGGCGTCTCGGGCTCGATCAGGACGTCGCGAACGACCGCCAACGTCAGGCCGAGATCAG
CAACTGGTTGGCGTCGCTCATTCGCCGCTGA

Upstream 100 bases:

>100_bases
CCTTAACCGGCCCGAGGTGCGGGAGCGGAGCGCGCAGTTCCTGCGCGGCGTTCTGAACCCGTGAGACCGCCATGCCTGTG
ATCGCTCGGAGATCGACGAC

Downstream 100 bases:

>100_bases
GCGATCACTTCATCAGCTGAATGATCAGCGGCGCCAGCGCGACGTTCATCAGCCCGACGAGCACCATCACGAGGCCGGCG
ATCGCGCCTTCCTCGCGGCC

Product: putative glutamine amidotransferase, class-I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MLKLLVLEGNSLAGRSRWAEIAGHTPSESYADVLRALAPDAVIDIATPADADARLPQPIDAYEGIVITGSALNIYQREPE
SLRQIELLRMIFAQGVPMFGSCWGLQLATVAAGGEVSLNPAGREVGFARKVVLTEAGRRHPLHEMRGEVFDAPAIHSDIV
TKLPPDATVTARNAMSEVQAAEIRSGHGRFWGVQYHPEFSLQDVAWVIRRIGQPLVDEGFFADAIELERYAADLASLHQD
RARRDLLWRLGLDQDVANDRQRQAEISNWLASLIRR

Sequences:

>Translated_276_residues
MLKLLVLEGNSLAGRSRWAEIAGHTPSESYADVLRALAPDAVIDIATPADADARLPQPIDAYEGIVITGSALNIYQREPE
SLRQIELLRMIFAQGVPMFGSCWGLQLATVAAGGEVSLNPAGREVGFARKVVLTEAGRRHPLHEMRGEVFDAPAIHSDIV
TKLPPDATVTARNAMSEVQAAEIRSGHGRFWGVQYHPEFSLQDVAWVIRRIGQPLVDEGFFADAIELERYAADLASLHQD
RARRDLLWRLGLDQDVANDRQRQAEISNWLASLIRR
>Mature_276_residues
MLKLLVLEGNSLAGRSRWAEIAGHTPSESYADVLRALAPDAVIDIATPADADARLPQPIDAYEGIVITGSALNIYQREPE
SLRQIELLRMIFAQGVPMFGSCWGLQLATVAAGGEVSLNPAGREVGFARKVVLTEAGRRHPLHEMRGEVFDAPAIHSDIV
TKLPPDATVTARNAMSEVQAAEIRSGHGRFWGVQYHPEFSLQDVAWVIRRIGQPLVDEGFFADAIELERYAADLASLHQD
RARRDLLWRLGLDQDVANDRQRQAEISNWLASLIRR

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GMP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR004739
- InterPro:   IPR022955
- InterPro:   IPR022310
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00117 GATase; PF00958 GMP_synt_C; PF02540 NAD_synthase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 30503; Mature: 30503

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLLVLEGNSLAGRSRWAEIAGHTPSESYADVLRALAPDAVIDIATPADADARLPQPID
CEEEEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
AYEGIVITGSALNIYQREPESLRQIELLRMIFAQGVPMFGSCWGLQLATVAAGGEVSLNP
CCCCEEEECCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEEECCCCEEECC
AGREVGFARKVVLTEAGRRHPLHEMRGEVFDAPAIHSDIVTKLPPDATVTARNAMSEVQA
CCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHH
AEIRSGHGRFWGVQYHPEFSLQDVAWVIRRIGQPLVDEGFFADAIELERYAADLASLHQD
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
RARRDLLWRLGLDQDVANDRQRQAEISNWLASLIRR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKLLVLEGNSLAGRSRWAEIAGHTPSESYADVLRALAPDAVIDIATPADADARLPQPID
CEEEEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
AYEGIVITGSALNIYQREPESLRQIELLRMIFAQGVPMFGSCWGLQLATVAAGGEVSLNP
CCCCEEEECCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEEECCCCEEECC
AGREVGFARKVVLTEAGRRHPLHEMRGEVFDAPAIHSDIVTKLPPDATVTARNAMSEVQA
CCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHH
AEIRSGHGRFWGVQYHPEFSLQDVAWVIRRIGQPLVDEGFFADAIELERYAADLASLHQD
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
RARRDLLWRLGLDQDVANDRQRQAEISNWLASLIRR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA