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The map label for this gene is cheA [H]

Identifier: 146337935

GI number: 146337935

Start: 876589

End: 878646

Strand: Reverse

Name: cheA [H]

Synonym: BRADO0825

Alternate gene names: 146337935

Gene position: 878646-876589 (Counterclockwise)

Preceding gene: 146337936

Following gene: 146337934

Centisome position: 11.78

GC content: 67.69

Gene sequence:

>2058_bases
ATGAGCACGCCCGACTGGACCGAATCGTTCCGACAGGAAGCCGCCGAGCTGTTCGAGACGCTCGAAGGCGCGCTGCTGGA
CCTCTGCGACACGCCCGACGATCGCGAGCTCGTCGACTGCGCGTTCCGCGCCCTGCATACCATCAAGGGATCGGGCGCGA
TGTTCGGCTTCGACAAGGTCGCGGCCTTCACGCATGAATTCGAGACCGCGTTCGATCGCGTCCGCAAGGGCGAGATCACG
CCGACGCGCGAGCTCATCACCGTGGCGCTCTCGGCCAAGGACTACATCCGCGCCCTGATCGACTCGCCCGACAGCACCGA
CACCATCATTGGCGACGGCATCCTCGACGATCTCCGCCGCTTCGTGACGCCGAGCACCGTGACGGACGCGCCGCCGCTGC
AGCCGTCGGCAACCGATCGAGTCGCCGGCGACGACAACGCCGTCGCGGGCTGGCGGCTGCATCTGGCGTTCGAGACGCAC
ATTCTGAGAAACGGCTCCAATCCGCTCAATTTCCTCGACGATCTCAGCAAGCTCGGCCCCTGCTTCGCCGTCGCGCTGAC
CGACGACGTGCCCCTGCTCGACGCGCTCGAGCCGGAGGACTGCTACCTGACATGGGACGTGACGCTGCACTGCTCATGCA
GCCGCGAGGTCATCGAGGACATCTTCATGTTCGTCCTCGAGGAGATGACGCTGTCGGCCACGCCGCTGACGCGGGGGGAG
CTGTCGCCCGTGGCCGCCGAGCCCGTGGCGCCGCCTGCACCGAAAGCACCCGAGCCGTCTGTGGCCGTCACCGAGCAGGC
TCCGCCACGGGCCAAGGACAAGGACGCCGATCGGGCGCCGGACCCGCGCCGCGAGGAGCCGAAGCGCGGCGACGATCGCG
CCATCGCCACCGTTCGCGTGCAGGCCCGCCGCCTCGATGAGATGATGGACCGCGTCGGCGAGCTCGTGATCGCCCAGGCG
CGGCTGAGCCAGCTCGCGGCCGCCAGCTCCGACCCGTCCATCAAGATCGTCGCCGAGGAGATCGAGCGGCTCGCCGGCAG
CCTGCGCGACACCACGATGGGCGCGCGCATGGTGCCGATCGGCTCGCTGTTCGGCCGCTTCCGCCGCCTCGTCCATGACC
TGTCGCTCGAATTGTCGAAGCCGGTGGACCTGATCACCTCGGGCGAGGACACCGAGCTCGACAAGACCATGATCGAATGC
CTCGCCGATCCCTTGGTGCACCTCATCCGCAACGCCATCGACCACGGCATCGAGCAGACCGCGGTCCGTCAGGCCGCCGG
CAAGACGGAGAAGGGCCGCATCGAGCTGCACGCGATTCATTCCGGCGCGCAGGTGCTCGTCACCGTGCGCGACAATGGCG
CGGGCCTCAACACGGCGCGCATCCGCGCCAAGGCCGAGGAGCAGGGTCTGCTCGCGCCGGACGCTGACATGTCCGACACC
GAGATTCACCAGTTCCTGTTTCACCCGGGCTTCTCGACCGCGCAGACGATCTCGGCGCTGTCCGGCCGCGGCGTCGGCAT
GGATGTGGTCAAGCGCACTATCGAGAACATGCGCGGCTCGATCGACATGGCGACGAAGCCGGGCGAAGGCACGACTGTCA
CGCTGCGGCTGCCGCTGACGCTCGCCATCATCGAGGGGCTGATGATCAGGGTCGGCGAAGGCCGCTACATCATTCCGCTG
TCGGCGGTGGAGGAATGCGTCGAGCTCACCGCGGAGGACCAGCGCGCGCGCGGCCGCAACTTCCTCAACATACGCGGCGA
CCTCGTGCCCTACCTGATGCTGCGCGACATCCTGCACGCCAACGGCATGCCGGACGAGTATCAGAAGACGATCATCGTCT
CGACCGGCGAGACCCGCGTCGGCCTGGTCGCCGACCAGATCATCGGCAGCCACCAGACCGTGATCAAGTCGCTGTCGAAG
CTGCACTCGGATGTCACGATCTTTTCCGGCGCCACCATCCTCGGTGACGGCACGGCGGCGCTGATCCTCGACGTCGCCCA
GCTGGTCGCGCTCGCGCAGGCGCATGCCGACAAGCAACATCTCCACGAGGCCGCCTGA

Upstream 100 bases:

>100_bases
CACTTCACGCACAAAACGGACGGTGTGTGATGTCCGCGATCCGCGCAGCCGGCTGGACCAGAGCACCGTTCATCTCGATC
GTCGCCCGGATGATCCGCCC

Downstream 100 bases:

>100_bases
TGAGCCAGCACACAGAGCACGCAGCCATTGGCGGCCAGTCGGCCCAGGTCGTCATGATCGGTCTCGGCGACGAGAAATTC
GCGCTCGATGCCGCGATCGT

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 684

Protein sequence:

>685_residues
MSTPDWTESFRQEAAELFETLEGALLDLCDTPDDRELVDCAFRALHTIKGSGAMFGFDKVAAFTHEFETAFDRVRKGEIT
PTRELITVALSAKDYIRALIDSPDSTDTIIGDGILDDLRRFVTPSTVTDAPPLQPSATDRVAGDDNAVAGWRLHLAFETH
ILRNGSNPLNFLDDLSKLGPCFAVALTDDVPLLDALEPEDCYLTWDVTLHCSCSREVIEDIFMFVLEEMTLSATPLTRGE
LSPVAAEPVAPPAPKAPEPSVAVTEQAPPRAKDKDADRAPDPRREEPKRGDDRAIATVRVQARRLDEMMDRVGELVIAQA
RLSQLAAASSDPSIKIVAEEIERLAGSLRDTTMGARMVPIGSLFGRFRRLVHDLSLELSKPVDLITSGEDTELDKTMIEC
LADPLVHLIRNAIDHGIEQTAVRQAAGKTEKGRIELHAIHSGAQVLVTVRDNGAGLNTARIRAKAEEQGLLAPDADMSDT
EIHQFLFHPGFSTAQTISALSGRGVGMDVVKRTIENMRGSIDMATKPGEGTTVTLRLPLTLAIIEGLMIRVGEGRYIIPL
SAVEECVELTAEDQRARGRNFLNIRGDLVPYLMLRDILHANGMPDEYQKTIIVSTGETRVGLVADQIIGSHQTVIKSLSK
LHSDVTIFSGATILGDGTAALILDVAQLVALAQAHADKQHLHEAA

Sequences:

>Translated_685_residues
MSTPDWTESFRQEAAELFETLEGALLDLCDTPDDRELVDCAFRALHTIKGSGAMFGFDKVAAFTHEFETAFDRVRKGEIT
PTRELITVALSAKDYIRALIDSPDSTDTIIGDGILDDLRRFVTPSTVTDAPPLQPSATDRVAGDDNAVAGWRLHLAFETH
ILRNGSNPLNFLDDLSKLGPCFAVALTDDVPLLDALEPEDCYLTWDVTLHCSCSREVIEDIFMFVLEEMTLSATPLTRGE
LSPVAAEPVAPPAPKAPEPSVAVTEQAPPRAKDKDADRAPDPRREEPKRGDDRAIATVRVQARRLDEMMDRVGELVIAQA
RLSQLAAASSDPSIKIVAEEIERLAGSLRDTTMGARMVPIGSLFGRFRRLVHDLSLELSKPVDLITSGEDTELDKTMIEC
LADPLVHLIRNAIDHGIEQTAVRQAAGKTEKGRIELHAIHSGAQVLVTVRDNGAGLNTARIRAKAEEQGLLAPDADMSDT
EIHQFLFHPGFSTAQTISALSGRGVGMDVVKRTIENMRGSIDMATKPGEGTTVTLRLPLTLAIIEGLMIRVGEGRYIIPL
SAVEECVELTAEDQRARGRNFLNIRGDLVPYLMLRDILHANGMPDEYQKTIIVSTGETRVGLVADQIIGSHQTVIKSLSK
LHSDVTIFSGATILGDGTAALILDVAQLVALAQAHADKQHLHEAA
>Mature_684_residues
STPDWTESFRQEAAELFETLEGALLDLCDTPDDRELVDCAFRALHTIKGSGAMFGFDKVAAFTHEFETAFDRVRKGEITP
TRELITVALSAKDYIRALIDSPDSTDTIIGDGILDDLRRFVTPSTVTDAPPLQPSATDRVAGDDNAVAGWRLHLAFETHI
LRNGSNPLNFLDDLSKLGPCFAVALTDDVPLLDALEPEDCYLTWDVTLHCSCSREVIEDIFMFVLEEMTLSATPLTRGEL
SPVAAEPVAPPAPKAPEPSVAVTEQAPPRAKDKDADRAPDPRREEPKRGDDRAIATVRVQARRLDEMMDRVGELVIAQAR
LSQLAAASSDPSIKIVAEEIERLAGSLRDTTMGARMVPIGSLFGRFRRLVHDLSLELSKPVDLITSGEDTELDKTMIECL
ADPLVHLIRNAIDHGIEQTAVRQAAGKTEKGRIELHAIHSGAQVLVTVRDNGAGLNTARIRAKAEEQGLLAPDADMSDTE
IHQFLFHPGFSTAQTISALSGRGVGMDVVKRTIENMRGSIDMATKPGEGTTVTLRLPLTLAIIEGLMIRVGEGRYIIPLS
AVEECVELTAEDQRARGRNFLNIRGDLVPYLMLRDILHANGMPDEYQKTIIVSTGETRVGLVADQIIGSHQTVIKSLSKL
HSDVTIFSGATILGDGTAALILDVAQLVALAQAHADKQHLHEAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=691, Percent_Identity=34.7322720694645, Blast_Score=343, Evalue=3e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74500; Mature: 74368

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPDWTESFRQEAAELFETLEGALLDLCDTPDDRELVDCAFRALHTIKGSGAMFGFDKV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
AAFTHEFETAFDRVRKGEITPTRELITVALSAKDYIRALIDSPDSTDTIIGDGILDDLRR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHH
FVTPSTVTDAPPLQPSATDRVAGDDNAVAGWRLHLAFETHILRNGSNPLNFLDDLSKLGP
HCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEHHHHCCCCCHHHHHHHHHCCC
CFAVALTDDVPLLDALEPEDCYLTWDVTLHCSCSREVIEDIFMFVLEEMTLSATPLTRGE
EEEEEEECCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
LSPVAAEPVAPPAPKAPEPSVAVTEQAPPRAKDKDADRAPDPRREEPKRGDDRAIATVRV
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHH
QARRLDEMMDRVGELVIAQARLSQLAAASSDPSIKIVAEEIERLAGSLRDTTMGARMVPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCEECHH
GSLFGRFRRLVHDLSLELSKPVDLITSGEDTELDKTMIECLADPLVHLIRNAIDHGIEQT
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVRQAAGKTEKGRIELHAIHSGAQVLVTVRDNGAGLNTARIRAKAEEQGLLAPDADMSDT
HHHHHHCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHEEECHHHCCCCCCCCCCCHH
EIHQFLFHPGFSTAQTISALSGRGVGMDVVKRTIENMRGSIDMATKPGEGTTVTLRLPLT
HHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCHH
LAIIEGLMIRVGEGRYIIPLSAVEECVELTAEDQRARGRNFLNIRGDLVPYLMLRDILHA
HHHHHHHHEEECCCCEEEEHHHHHHHHHHCCHHHHHCCCCEEEECHHHHHHHHHHHHHHC
NGMPDEYQKTIIVSTGETRVGLVADQIIGSHQTVIKSLSKLHSDVTIFSGATILGDGTAA
CCCCCHHCCEEEEECCCCEEHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCEEECCCHHH
LILDVAQLVALAQAHADKQHLHEAA
HHHHHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
STPDWTESFRQEAAELFETLEGALLDLCDTPDDRELVDCAFRALHTIKGSGAMFGFDKV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
AAFTHEFETAFDRVRKGEITPTRELITVALSAKDYIRALIDSPDSTDTIIGDGILDDLRR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHH
FVTPSTVTDAPPLQPSATDRVAGDDNAVAGWRLHLAFETHILRNGSNPLNFLDDLSKLGP
HCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEHHHHCCCCCHHHHHHHHHCCC
CFAVALTDDVPLLDALEPEDCYLTWDVTLHCSCSREVIEDIFMFVLEEMTLSATPLTRGE
EEEEEEECCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
LSPVAAEPVAPPAPKAPEPSVAVTEQAPPRAKDKDADRAPDPRREEPKRGDDRAIATVRV
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHH
QARRLDEMMDRVGELVIAQARLSQLAAASSDPSIKIVAEEIERLAGSLRDTTMGARMVPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCEECHH
GSLFGRFRRLVHDLSLELSKPVDLITSGEDTELDKTMIECLADPLVHLIRNAIDHGIEQT
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVRQAAGKTEKGRIELHAIHSGAQVLVTVRDNGAGLNTARIRAKAEEQGLLAPDADMSDT
HHHHHHCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHEEECHHHCCCCCCCCCCCHH
EIHQFLFHPGFSTAQTISALSGRGVGMDVVKRTIENMRGSIDMATKPGEGTTVTLRLPLT
HHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCHH
LAIIEGLMIRVGEGRYIIPLSAVEECVELTAEDQRARGRNFLNIRGDLVPYLMLRDILHA
HHHHHHHHEEECCCCEEEEHHHHHHHHHHCCHHHHHCCCCEEEECHHHHHHHHHHHHHHC
NGMPDEYQKTIIVSTGETRVGLVADQIIGSHQTVIKSLSKLHSDVTIFSGATILGDGTAA
CCCCCHHCCEEEEECCCCEEHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCEEECCCHHH
LILDVAQLVALAQAHADKQHLHEAA
HHHHHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]