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The map label for this gene is nudH [H]

Identifier: 146337568

GI number: 146337568

Start: 433984

End: 434490

Strand: Reverse

Name: nudH [H]

Synonym: BRADO0423

Alternate gene names: 146337568

Gene position: 434490-433984 (Counterclockwise)

Preceding gene: 146337569

Following gene: 146337567

Centisome position: 5.83

GC content: 67.46

Gene sequence:

>507_bases
ATGACGCGCTACGAGGACCTGCCCTACCGCACCTGCGTCGGCATCGCGCTGATCAACTCGGAAGGGCTGGTGTTCATCGG
TCGCCGCGCCGGAGGCATCGAGCATGTCGACGACACCCATGTCTGGCAGATGCCGCAGGGCGGCGTCGATCCCGGCGAGG
ACGCCTGGGAAGCCGCCAAGCGCGAGCTTTATGAGGAGACCAGCGTCCGCTCGGTCGAGAAGCTCGCCGAGATCGACGAC
TGGCTGACCTACGACATCCCGCGCACGGTGGCCGGCCGGGCGTGGAAGGGCCGCTACCGCGGCCAGCGCCAGAAATGGTT
CGCGCTGCGCTTCACCGGCAAGGATTCCGAGATCGACGTCGAACACCCTGGCGGCGGCCACCACAAGGCGGAGTTCATCA
CCTGGCGCTGGGAGCCGCTGCAGAACCTGCCGACGCTGATCGTGCCATTCAAGCGGCCGGTCTATGAGCGGGTGGCCAAG
GAATTCGCGACGCTGGCGGGCGGCTGA

Upstream 100 bases:

>100_bases
GAAATCAAAATCGAACTGAACGAGCGTACGCCACCGCGGCGGCGACGTGACGCGGGGTCTGTCGCGACGGGGCGGGGCAA
CGCAGGAAGGCCGAGACGGA

Downstream 100 bases:

>100_bases
GCGCGCTTCGGGCTTCGACCATCCCCATCGACCGCTCGGCGCGATCTGCACGGCCGTTGCACGGCATCCCTGCAGACCCG
CCGCGACACCGCCGTCACGC

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MTRYEDLPYRTCVGIALINSEGLVFIGRRAGGIEHVDDTHVWQMPQGGVDPGEDAWEAAKRELYEETSVRSVEKLAEIDD
WLTYDIPRTVAGRAWKGRYRGQRQKWFALRFTGKDSEIDVEHPGGGHHKAEFITWRWEPLQNLPTLIVPFKRPVYERVAK
EFATLAGG

Sequences:

>Translated_168_residues
MTRYEDLPYRTCVGIALINSEGLVFIGRRAGGIEHVDDTHVWQMPQGGVDPGEDAWEAAKRELYEETSVRSVEKLAEIDD
WLTYDIPRTVAGRAWKGRYRGQRQKWFALRFTGKDSEIDVEHPGGGHHKAEFITWRWEPLQNLPTLIVPFKRPVYERVAK
EFATLAGG
>Mature_167_residues
TRYEDLPYRTCVGIALINSEGLVFIGRRAGGIEHVDDTHVWQMPQGGVDPGEDAWEAAKRELYEETSVRSVEKLAEIDDW
LTYDIPRTVAGRAWKGRYRGQRQKWFALRFTGKDSEIDVEHPGGGHHKAEFITWRWEPLQNLPTLIVPFKRPVYERVAKE
FATLAGG

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=164, Percent_Identity=39.6341463414634, Blast_Score=105, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 19269; Mature: 19138

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYEDLPYRTCVGIALINSEGLVFIGRRAGGIEHVDDTHVWQMPQGGVDPGEDAWEAAK
CCCCCCCCCHHEEEEEEECCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHH
RELYEETSVRSVEKLAEIDDWLTYDIPRTVAGRAWKGRYRGQRQKWFALRFTGKDSEIDV
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCEEEEEEEECCCCEEEE
EHPGGGHHKAEFITWRWEPLQNLPTLIVPFKRPVYERVAKEFATLAGG
ECCCCCCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRYEDLPYRTCVGIALINSEGLVFIGRRAGGIEHVDDTHVWQMPQGGVDPGEDAWEAAK
CCCCCCCCHHEEEEEEECCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHH
RELYEETSVRSVEKLAEIDDWLTYDIPRTVAGRAWKGRYRGQRQKWFALRFTGKDSEIDV
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCEEEEEEEECCCCEEEE
EHPGGGHHKAEFITWRWEPLQNLPTLIVPFKRPVYERVAKEFATLAGG
ECCCCCCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA