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The map label for this gene is yccK [H]

Identifier: 146337242

GI number: 146337242

Start: 77907

End: 78911

Strand: Direct

Name: yccK [H]

Synonym: BRADO0068

Alternate gene names: 146337242

Gene position: 77907-78911 (Clockwise)

Preceding gene: 146337240

Following gene: 146337244

Centisome position: 1.04

GC content: 67.36

Gene sequence:

>1005_bases
ATGGAAACCCGCCAACTTGGAAAAGCCGGCCCAATGGTCTCCGCGCTCGGCCTCGGCTGCATGGGCATGTCCGACTTCTA
CGGCCCGAATGACCGCGCCGAGAGCATCGCGACGATTCACGCCGCCCTCGATGCCGGCATCATGCTGATCGACACCGGCG
ACTTCTACGGCATGGGCCACAACGAGATGCTGATCCGCGAGGCGCTCGCCTCGGCCGGCCCGCGCAACGTGCAGATCTCG
GTGAAATTCGGCGCGCTGCGCGGGCCTGACAAGAGCTGGCTCGGTTATGACAGCCGCCCGGAAGCCGTGCGAACCTTCCT
GTCCTATTCGCTGCAACGGCTCGGTGTCGACGCCATCGACATCTACCGCCCGGCGCGGCTCGATCCGAACGTGCCGATAG
AGGACACGATCGGCGCGATGGCCGAGCTGAAGCAGGCCGGCTTCATCAGGCATATCGGCCTGTCCGAGGTCGGCTCCGAG
ACCATCCGCCGGGCGCACAAGGTGCATCCGATCTCGGACCTGCAGATCGAGTATTCGCTGATTTCGCGCGGCATCGAGAG
CGACATCCTCAAGACCTGCCGCGAGCTCGGCATCGGCATCACCGCCTATGGCGTGCTGTCGCGCGGCCTGATCAGCGGGC
ATTGGTCGAAGGACCGCGGTGGCGTCAGCGACTTCCGCGGTCATTCACCGCGCTTCCAGGGCGACAATCTCGATCGCAAT
CTCGGCCTCGTCGAGACGCTGCGCAGCATCGCGGCCGATGTCGGCGCGACGCCGGCGCAGGTCGCGATCGCCTGGGTGGC
CGCGCAAGGCAATGACATCGTCCCGCTGGTCGGCGCCCGCCGCCGCGACCGCCTCGACGAGGCGCTCGGCGCGCTCTGCG
TCAAGCTCACCGAGGTCCAGCTCGCCGCGCTCGACAAGGCCTTCCCGCCCGGCGTCGCCGCGGGAGAACGCTATCCGGAG
TCGCAGCTGGTGCACATGGACAGCGAGCGCGCGAAGGGGGAGTAA

Upstream 100 bases:

>100_bases
ACAGCCTATTCTGAATTGTCCAGCTTATCGAATTGCGGAATTGGGCCGATATCCGCGTTGTCAGGCGTCCACGCAGGCCG
CCTCAACAAGGAGATTGATC

Downstream 100 bases:

>100_bases
GACGCTCAGCGCGACCTCCAAATTCAGTGTCGTCCCGGCGAACGCCGGGACCCATACCCCAGGGTGCAGTTTGAGGCACG
CTGGTCATTGGCTTTTGCCC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
METRQLGKAGPMVSALGLGCMGMSDFYGPNDRAESIATIHAALDAGIMLIDTGDFYGMGHNEMLIREALASAGPRNVQIS
VKFGALRGPDKSWLGYDSRPEAVRTFLSYSLQRLGVDAIDIYRPARLDPNVPIEDTIGAMAELKQAGFIRHIGLSEVGSE
TIRRAHKVHPISDLQIEYSLISRGIESDILKTCRELGIGITAYGVLSRGLISGHWSKDRGGVSDFRGHSPRFQGDNLDRN
LGLVETLRSIAADVGATPAQVAIAWVAAQGNDIVPLVGARRRDRLDEALGALCVKLTEVQLAALDKAFPPGVAAGERYPE
SQLVHMDSERAKGE

Sequences:

>Translated_334_residues
METRQLGKAGPMVSALGLGCMGMSDFYGPNDRAESIATIHAALDAGIMLIDTGDFYGMGHNEMLIREALASAGPRNVQIS
VKFGALRGPDKSWLGYDSRPEAVRTFLSYSLQRLGVDAIDIYRPARLDPNVPIEDTIGAMAELKQAGFIRHIGLSEVGSE
TIRRAHKVHPISDLQIEYSLISRGIESDILKTCRELGIGITAYGVLSRGLISGHWSKDRGGVSDFRGHSPRFQGDNLDRN
LGLVETLRSIAADVGATPAQVAIAWVAAQGNDIVPLVGARRRDRLDEALGALCVKLTEVQLAALDKAFPPGVAAGERYPE
SQLVHMDSERAKGE
>Mature_334_residues
METRQLGKAGPMVSALGLGCMGMSDFYGPNDRAESIATIHAALDAGIMLIDTGDFYGMGHNEMLIREALASAGPRNVQIS
VKFGALRGPDKSWLGYDSRPEAVRTFLSYSLQRLGVDAIDIYRPARLDPNVPIEDTIGAMAELKQAGFIRHIGLSEVGSE
TIRRAHKVHPISDLQIEYSLISRGIESDILKTCRELGIGITAYGVLSRGLISGHWSKDRGGVSDFRGHSPRFQGDNLDRN
LGLVETLRSIAADVGATPAQVAIAWVAAQGNDIVPLVGARRRDRLDEALGALCVKLTEVQLAALDKAFPPGVAAGERYPE
SQLVHMDSERAKGE

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=307, Percent_Identity=28.0130293159609, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI4504825, Length=304, Percent_Identity=27.9605263157895, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI27436971, Length=307, Percent_Identity=27.6872964169381, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI27436964, Length=307, Percent_Identity=26.7100977198697, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI27436962, Length=307, Percent_Identity=26.7100977198697, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI27436966, Length=307, Percent_Identity=26.7100977198697, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI223718702, Length=315, Percent_Identity=25.3968253968254, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI41327764, Length=275, Percent_Identity=24.7272727272727, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI41152114, Length=315, Percent_Identity=24.4444444444444, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081735, Length=332, Percent_Identity=30.7228915662651, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788070, Length=314, Percent_Identity=30.8917197452229, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787674, Length=302, Percent_Identity=30.794701986755, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789375, Length=332, Percent_Identity=28.0120481927711, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=28.0346820809249, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788081, Length=301, Percent_Identity=25.9136212624585, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325384, Length=333, Percent_Identity=27.027027027027, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323998, Length=343, Percent_Identity=26.2390670553936, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6325169, Length=349, Percent_Identity=24.0687679083095, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=305, Percent_Identity=24.5901639344262, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=215, Percent_Identity=26.9767441860465, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24646159, Length=223, Percent_Identity=28.6995515695067, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640980, Length=324, Percent_Identity=26.5432098765432, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45549126, Length=321, Percent_Identity=26.791277258567, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646155, Length=160, Percent_Identity=31.25, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36001; Mature: 36001

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRQLGKAGPMVSALGLGCMGMSDFYGPNDRAESIATIHAALDAGIMLIDTGDFYGMGH
CCCHHCCCCCCHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCC
NEMLIREALASAGPRNVQISVKFGALRGPDKSWLGYDSRPEAVRTFLSYSLQRLGVDAID
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
IYRPARLDPNVPIEDTIGAMAELKQAGFIRHIGLSEVGSETIRRAHKVHPISDLQIEYSL
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHEEEHHH
ISRGIESDILKTCRELGIGITAYGVLSRGLISGHWSKDRGGVSDFRGHSPRFQGDNLDRN
HHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCC
LGLVETLRSIAADVGATPAQVAIAWVAAQGNDIVPLVGARRRDRLDEALGALCVKLTEVQ
CCHHHHHHHHHHHCCCCHHHEEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
LAALDKAFPPGVAAGERYPESQLVHMDSERAKGE
HHHHHHCCCCCCCCCCCCCCCCEEECCCHHCCCC
>Mature Secondary Structure
METRQLGKAGPMVSALGLGCMGMSDFYGPNDRAESIATIHAALDAGIMLIDTGDFYGMGH
CCCHHCCCCCCHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCC
NEMLIREALASAGPRNVQISVKFGALRGPDKSWLGYDSRPEAVRTFLSYSLQRLGVDAID
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
IYRPARLDPNVPIEDTIGAMAELKQAGFIRHIGLSEVGSETIRRAHKVHPISDLQIEYSL
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHEEEHHH
ISRGIESDILKTCRELGIGITAYGVLSRGLISGHWSKDRGGVSDFRGHSPRFQGDNLDRN
HHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCC
LGLVETLRSIAADVGATPAQVAIAWVAAQGNDIVPLVGARRRDRLDEALGALCVKLTEVQ
CCHHHHHHHHHHHCCCCHHHEEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
LAALDKAFPPGVAAGERYPESQLVHMDSERAKGE
HHHHHHCCCCCCCCCCCCCCCCEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]