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The map label for this gene is fur [H]

Identifier: 146337213

GI number: 146337213

Start: 45318

End: 45770

Strand: Direct

Name: fur [H]

Synonym: BRADO0039

Alternate gene names: 146337213

Gene position: 45318-45770 (Clockwise)

Preceding gene: 146337212

Following gene: 146337214

Centisome position: 0.61

GC content: 63.36

Gene sequence:

>453_bases
ATGACTTCCTTGAAGACAACGCCAGCGCCCAATTCCACCGGTATCGAGGCCCGTTGCGCCGCCACCGGCATGCGGATGAC
CGAGCAGCGCCGGGTCATCGCCCGCGTGCTCGCCGAGGCGAGCGACCATCCCGACGTCGAGGAACTGTATCGGCGCTGTG
TCGCGGTCGACGACAAGATCTCGATCTCCACGGTCTACCGGACCGTGAAGCTGTTCGAGGACGCCGGCATCATCGAGCGT
CACGATTTCCGCGAAGGCCGTGCCCGCTACGAGCAGATGCGTGACAGCCATCACGACCACCTGATCAATCTGCGTGACGG
CAAGGTGATCGAGTTCACCTCCGAGGAGATCGAGAAGCTGCAGGCCGAGATCGCCCGCAGGCTCGGCTACAAGCTGGTCG
ACCACCGGCTCGAGCTGTATTGCGTGCCGCTCGACGAAGAGACGAATGGCTGA

Upstream 100 bases:

>100_bases
CTGCAGCCTGGCGGGGAACAGTTGAACGCGCTTCTGATGCGCCGGGACTTGTCGTAACCTGCGCTTGGTGGCAGAAAGCG
CATCCTTGAGGCGAGACACA

Downstream 100 bases:

>100_bases
CGCGGCTCCGCCTTCCCCGCTCGATCTCGTCATTTTTGATTGCGACGGCGTGCTGGTCGACAGCGAGGTGATCTCCTGTC
AGGCGCACGCCGACGTGCTT

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTSLKTTPAPNSTGIEARCAATGMRMTEQRRVIARVLAEASDHPDVEELYRRCVAVDDKISISTVYRTVKLFEDAGIIER
HDFREGRARYEQMRDSHHDHLINLRDGKVIEFTSEEIEKLQAEIARRLGYKLVDHRLELYCVPLDEETNG

Sequences:

>Translated_150_residues
MTSLKTTPAPNSTGIEARCAATGMRMTEQRRVIARVLAEASDHPDVEELYRRCVAVDDKISISTVYRTVKLFEDAGIIER
HDFREGRARYEQMRDSHHDHLINLRDGKVIEFTSEEIEKLQAEIARRLGYKLVDHRLELYCVPLDEETNG
>Mature_149_residues
TSLKTTPAPNSTGIEARCAATGMRMTEQRRVIARVLAEASDHPDVEELYRRCVAVDDKISISTVYRTVKLFEDAGIIERH
DFREGRARYEQMRDSHHDHLINLRDGKVIEFTSEEIEKLQAEIARRLGYKLVDHRLELYCVPLDEETNG

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=120, Percent_Identity=43.3333333333333, Blast_Score=101, Evalue=2e-23,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17287; Mature: 17156

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLKTTPAPNSTGIEARCAATGMRMTEQRRVIARVLAEASDHPDVEELYRRCVAVDDKI
CCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
SISTVYRTVKLFEDAGIIERHDFREGRARYEQMRDSHHDHLINLRDGKVIEFTSEEIEKL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECHHHHHHH
QAEIARRLGYKLVDHRLELYCVPLDEETNG
HHHHHHHHHHHHHHCCEEEEEEECCCCCCC
>Mature Secondary Structure 
TSLKTTPAPNSTGIEARCAATGMRMTEQRRVIARVLAEASDHPDVEELYRRCVAVDDKI
CCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
SISTVYRTVKLFEDAGIIERHDFREGRARYEQMRDSHHDHLINLRDGKVIEFTSEEIEKL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECHHHHHHH
QAEIARRLGYKLVDHRLELYCVPLDEETNG
HHHHHHHHHHHHHHCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9835040 [H]