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The map label for this gene is lytT [H]

Identifier: 146302755

GI number: 146302755

Start: 6066708

End: 6067421

Strand: Reverse

Name: lytT [H]

Synonym: Fjoh_5028

Alternate gene names: 146302755

Gene position: 6067421-6066708 (Counterclockwise)

Preceding gene: 146302756

Following gene: 146302752

Centisome position: 99.52

GC content: 35.01

Gene sequence:

>714_bases
ATGAACATGAAATGCCTCGTTATAGACGATGAACCTATTGCAAGAAACGGAATCGTAGATTTTATTTCTAAAATTGATTT
TCTGGAAGCTGCAGGCACATGTGCTTCGGCATTAGAAGCGACTTCGTATCTTCAGGAAAAGCAAATCGATTTGATGTTTC
TCGATATCAATATGCCTTATCTTACCGGATTAGAGTTTCTGGAAGCATTAGATAATCCGCCATTGGTGATTTTTACAACT
GCTTATTCAGAACATGCTCTAGACGGATATCGGTTACAGGTTGTAGATTATTTATTAAAACCTATTACGTTTCAACGCTT
TTATCAGGCATCTTTAAAAGCCAGACAATGGCATCAAATGATGCACGCTCCAAAACAAAATCAATTAGATCCGTTTTTAT
ATGTGCGTCAGGAAGAAGGATTTCAGAAAATTTCCTGGGTAGATATTTTATATATTGAAGGAATGCAGAATTATGCTAAA
CTTCATTTTAAAGAAAAAGTCATTGTAATTCATCAAACCATGATTTCATTAGAAGAAACACTTCCGGCAGAGATTTTCTT
TAGAATTCATAAATCATTTTTAGTAAACATCACTCATATCGATTCTGTTTCGGGCGGACGATTATTTATAAAAGGACAAG
AACTACCAATTTCAAGAACCCGCCGCGAGGCATTATTGAAAGAGGTAGTCTATAAAAACTTATTAAGCAGGTAG

Upstream 100 bases:

>100_bases
TCCTTTGCGGTTAAATTTTTTAGCCACAGATTACACAGATTAAAAGGATTAAAAAAATATTAAACCTGAAACAAAGAAAA
CCTGAAACAAAAACAATATT

Downstream 100 bases:

>100_bases
CTCTAGAATTTCCATTTTAGAGCTATTGCTCCGTAAAAAGTAGTAGTAAATCTTGGATCGGCTATATCTTTTTCTTTAAA
AATATCTTTAATCTTTCTAT

Product: LytTR family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MNMKCLVIDDEPIARNGIVDFISKIDFLEAAGTCASALEATSYLQEKQIDLMFLDINMPYLTGLEFLEALDNPPLVIFTT
AYSEHALDGYRLQVVDYLLKPITFQRFYQASLKARQWHQMMHAPKQNQLDPFLYVRQEEGFQKISWVDILYIEGMQNYAK
LHFKEKVIVIHQTMISLEETLPAEIFFRIHKSFLVNITHIDSVSGGRLFIKGQELPISRTRREALLKEVVYKNLLSR

Sequences:

>Translated_237_residues
MNMKCLVIDDEPIARNGIVDFISKIDFLEAAGTCASALEATSYLQEKQIDLMFLDINMPYLTGLEFLEALDNPPLVIFTT
AYSEHALDGYRLQVVDYLLKPITFQRFYQASLKARQWHQMMHAPKQNQLDPFLYVRQEEGFQKISWVDILYIEGMQNYAK
LHFKEKVIVIHQTMISLEETLPAEIFFRIHKSFLVNITHIDSVSGGRLFIKGQELPISRTRREALLKEVVYKNLLSR
>Mature_237_residues
MNMKCLVIDDEPIARNGIVDFISKIDFLEAAGTCASALEATSYLQEKQIDLMFLDINMPYLTGLEFLEALDNPPLVIFTT
AYSEHALDGYRLQVVDYLLKPITFQRFYQASLKARQWHQMMHAPKQNQLDPFLYVRQEEGFQKISWVDILYIEGMQNYAK
LHFKEKVIVIHQTMISLEETLPAEIFFRIHKSFLVNITHIDSVSGGRLFIKGQELPISRTRREALLKEVVYKNLLSR

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=230, Percent_Identity=27.8260869565217, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1788724, Length=235, Percent_Identity=26.8085106382979, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27550; Mature: 27550

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMKCLVIDDEPIARNGIVDFISKIDFLEAAGTCASALEATSYLQEKQIDLMFLDINMPY
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCH
LTGLEFLEALDNPPLVIFTTAYSEHALDGYRLQVVDYLLKPITFQRFYQASLKARQWHQM
HHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
MHAPKQNQLDPFLYVRQEEGFQKISWVDILYIEGMQNYAKLHFKEKVIVIHQTMISLEET
HCCCCCCCCCCEEEEECCCCCCEEHHEEEEEECCHHHHHHHHHHCEEEEEHHHHHHHHHH
LPAEIFFRIHKSFLVNITHIDSVSGGRLFIKGQELPISRTRREALLKEVVYKNLLSR
CCHHHHHHHHHHHHEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNMKCLVIDDEPIARNGIVDFISKIDFLEAAGTCASALEATSYLQEKQIDLMFLDINMPY
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCH
LTGLEFLEALDNPPLVIFTTAYSEHALDGYRLQVVDYLLKPITFQRFYQASLKARQWHQM
HHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
MHAPKQNQLDPFLYVRQEEGFQKISWVDILYIEGMQNYAKLHFKEKVIVIHQTMISLEET
HCCCCCCCCCCEEEEECCCCCCEEHHEEEEEECCHHHHHHHHHHCEEEEEHHHHHHHHHH
LPAEIFFRIHKSFLVNITHIDSVSGGRLFIKGQELPISRTRREALLKEVVYKNLLSR
CCHHHHHHHHHHHHEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]