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The map label for this gene is ahpC [C]

Identifier: 146302744

GI number: 146302744

Start: 6056062

End: 6056700

Strand: Reverse

Name: ahpC [C]

Synonym: Fjoh_5017

Alternate gene names: 146302744

Gene position: 6056700-6056062 (Counterclockwise)

Preceding gene: 146302745

Following gene: 146302739

Centisome position: 99.34

GC content: 36.15

Gene sequence:

>639_bases
ATGTCAACATTAAGATTAGGCGATATAGCTCCGGATTTTCACGCAGAAACCACACAAGGACCAATCAATTTTCATGAATG
GTTAGGAGATTCTTGGGGCGTTTTATTTTCGCATCCTGCAGATTTTACTCCTGTTTGTACAACTGAGTTGGGAACAGTAG
CGAATTATGTTCCGGAATTTACCAAAAGAAATACTAAGGTTATTGCTTTGAGTGTAGACGGATTAGATTCTCACAAAGAG
TGGATTAAAGACATTAATGAAACTCAAAATACAGAAGTGAATTTTCCAATTATTGCCGATGAAGATAAAAAAGTAGCGAA
TTTATACGATATGCTTCATCCCAATGCAAGCGATAAATTTACAGTACGTTCTGTTTTTGTTATTGGACCAGATAAAAAAA
TCAAATTAACATTGACTTATCCAGCTTCGACAGGAAGAAATTTTGATGAATTACTTCGCGTAATTGACAGTTTACAATTA
ACTGCAAATTACAGCGTTGCAACTCCTGCAAATTGGAAAGATGGAGAAGATGTAGTAATTGCACCTGCAATTCCTGACAG
CGATATTCCGGCAAAATTCCCAAAAGGACACAAGCCTATTAAACCTTACTTAAGATTGACACCGCAGCCTAATAAGTAA

Upstream 100 bases:

>100_bases
AATTAGATAGAGCTTATAGAATTTTAACTTTTTTTTAATTCTTACGTGTTTTCTAAATGTATTTTTTAGTTAATTTTAGA
GGAACTAAAAAATATAAATT

Downstream 100 bases:

>100_bases
TTTGAGGTTCTGAGTTGCTAAGGTACTAAGGTTCTAAGTTTTTTTCTTAGAATTTTAGTATTTTTTTTCTGAAAATAAAC
AAAGCGCAAGATTTCAAAAT

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSTLRLGDIAPDFHAETTQGPINFHEWLGDSWGVLFSHPADFTPVCTTELGTVANYVPEFTKRNTKVIALSVDGLDSHKE
WIKDINETQNTEVNFPIIADEDKKVANLYDMLHPNASDKFTVRSVFVIGPDKKIKLTLTYPASTGRNFDELLRVIDSLQL
TANYSVATPANWKDGEDVVIAPAIPDSDIPAKFPKGHKPIKPYLRLTPQPNK

Sequences:

>Translated_212_residues
MSTLRLGDIAPDFHAETTQGPINFHEWLGDSWGVLFSHPADFTPVCTTELGTVANYVPEFTKRNTKVIALSVDGLDSHKE
WIKDINETQNTEVNFPIIADEDKKVANLYDMLHPNASDKFTVRSVFVIGPDKKIKLTLTYPASTGRNFDELLRVIDSLQL
TANYSVATPANWKDGEDVVIAPAIPDSDIPAKFPKGHKPIKPYLRLTPQPNK
>Mature_211_residues
STLRLGDIAPDFHAETTQGPINFHEWLGDSWGVLFSHPADFTPVCTTELGTVANYVPEFTKRNTKVIALSVDGLDSHKEW
IKDINETQNTEVNFPIIADEDKKVANLYDMLHPNASDKFTVRSVFVIGPDKKIKLTLTYPASTGRNFDELLRVIDSLQLT
ANYSVATPANWKDGEDVVIAPAIPDSDIPAKFPKGHKPIKPYLRLTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=220, Percent_Identity=55.9090909090909, Blast_Score=238, Evalue=2e-63,
Organism=Homo sapiens, GI32189392, Length=187, Percent_Identity=31.5508021390374, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4505591, Length=180, Percent_Identity=30, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI32455266, Length=180, Percent_Identity=30, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI32455264, Length=180, Percent_Identity=30, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI5453549, Length=149, Percent_Identity=31.5436241610738, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32483377, Length=140, Percent_Identity=31.4285714285714, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI5802974, Length=140, Percent_Identity=31.4285714285714, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=33.1168831168831, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25153706, Length=203, Percent_Identity=39.4088669950739, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32565831, Length=191, Percent_Identity=30.8900523560209, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193204376, Length=191, Percent_Identity=30.8900523560209, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17554494, Length=157, Percent_Identity=29.2993630573248, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319407, Length=211, Percent_Identity=54.0284360189574, Blast_Score=221, Evalue=9e-59,
Organism=Drosophila melanogaster, GI24581278, Length=217, Percent_Identity=51.1520737327189, Blast_Score=224, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24652436, Length=201, Percent_Identity=52.2388059701493, Blast_Score=204, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24652434, Length=201, Percent_Identity=52.2388059701493, Blast_Score=204, Evalue=4e-53,
Organism=Drosophila melanogaster, GI17975518, Length=201, Percent_Identity=52.2388059701493, Blast_Score=203, Evalue=6e-53,
Organism=Drosophila melanogaster, GI21357347, Length=187, Percent_Identity=28.8770053475936, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=29.3785310734463, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17157991, Length=149, Percent_Identity=32.8859060402685, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641739, Length=149, Percent_Identity=32.8859060402685, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24656348, Length=160, Percent_Identity=28.75, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17864676, Length=160, Percent_Identity=28.75, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23629; Mature: 23498

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLRLGDIAPDFHAETTQGPINFHEWLGDSWGVLFSHPADFTPVCTTELGTVANYVPEF
CCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHH
TKRNTKVIALSVDGLDSHKEWIKDINETQNTEVNFPIIADEDKKVANLYDMLHPNASDKF
HCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEECCCEEECCCCHHHHHHHHHCCCCCCCE
TVRSVFVIGPDKKIKLTLTYPASTGRNFDELLRVIDSLQLTANYSVATPANWKDGEDVVI
EEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHEEEECCEECCCCCCCCCCCEEE
APAIPDSDIPAKFPKGHKPIKPYLRLTPQPNK
ECCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure 
STLRLGDIAPDFHAETTQGPINFHEWLGDSWGVLFSHPADFTPVCTTELGTVANYVPEF
CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHH
TKRNTKVIALSVDGLDSHKEWIKDINETQNTEVNFPIIADEDKKVANLYDMLHPNASDKF
HCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEECCCEEECCCCHHHHHHHHHCCCCCCCE
TVRSVFVIGPDKKIKLTLTYPASTGRNFDELLRVIDSLQLTANYSVATPANWKDGEDVVI
EEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHEEEECCEECCCCCCCCCCCEEE
APAIPDSDIPAKFPKGHKPIKPYLRLTPQPNK
ECCCCCCCCCCCCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]