Click here to switch to the map view.

The map label for this gene is dnaQ [H]

Identifier: 146302714

GI number: 146302714

Start: 6022977

End: 6023747

Strand: Reverse

Name: dnaQ [H]

Synonym: Fjoh_4987

Alternate gene names: 146302714

Gene position: 6023747-6022977 (Counterclockwise)

Preceding gene: 146302715

Following gene: 146302713

Centisome position: 98.8

GC content: 36.45

Gene sequence:

>771_bases
ATGGAATTAAAACTTAACAAACCAATCTGCTTTTTTGACCTTGAAACAACTGGAATTGATATCGGTAAAGATCGAATAGT
AGAAATTTCGATATTTAAAGTTTTTCCAAACGGAAATAAAGAAAGTAAAACCTGGCTGGTTAATCCAACAATTCCAATTC
CTCCACAAACTACGGCGGTTCACGGCATTACTGATGAAAAGGTAGCCAACGAACCAACCTTTGCCGAACTTGCTCCGCTG
GTTCATAATATGATAAAAGACAGCGATCTTGCAGGTTTTAATTCAGATCGTTTTGATATTCCGCTGCTGGCAGAAGAACT
GCTTCGTGCCGGAGTTGATTTTGATATGAAAAATAAAGTTTCGGTAGATGTTCAGACTATTTTTCATAAAATGGAAGAGC
GTACATTAAGTGCGGCTTTAAAGTTTTACTGCGGAAAAAGTCTTGATAATGCACACTCTGCAGAAGCGGATACAATGGCA
ACTTACGAAATTTTAAAAGCGCAGTTAGATCGTTATCCGGAATTAGAAAACGATATGAAATCATTGTCTGAGTTTACAAC
TCGTAAACGAATTGCTGATTTTGCCGGAATGATCGCTTTTGATAATGATGATGAAGAAATCTTTACTTTCGGAAAACACA
AAGGGGCAAAAGTTGAAAAAGTACTGGAAACAGAGCCTGGATATTTCAGCTGGATTCAAAACGCCGATTTTCCTTTGTAC
ACCAAAAAAGTTCTGACAGGGATTAAATTGAGAAAATTAAATACAAAATAA

Upstream 100 bases:

>100_bases
CAAAACCAACAAAAAAAGCCAATTTTGGTCAAAAAAATAAGAATTTGCTCAGGAACTTTGGCTTTAAAAAATTACATTTG
TAATCTTATAAAAATTAAAA

Downstream 100 bases:

>100_bases
GATTCTGAGTTACTGAGCTTCTATGGTTCTAAGTTTTTTTTCCTTAGCAGCTCAGTAACTTGGTATCTCAGTACCTTTAA
AAAAAATGAAAATCATTTGT

Product: exonuclease, RNase T and DNA polymerase III

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MELKLNKPICFFDLETTGIDIGKDRIVEISIFKVFPNGNKESKTWLVNPTIPIPPQTTAVHGITDEKVANEPTFAELAPL
VHNMIKDSDLAGFNSDRFDIPLLAEELLRAGVDFDMKNKVSVDVQTIFHKMEERTLSAALKFYCGKSLDNAHSAEADTMA
TYEILKAQLDRYPELENDMKSLSEFTTRKRIADFAGMIAFDNDDEEIFTFGKHKGAKVEKVLETEPGYFSWIQNADFPLY
TKKVLTGIKLRKLNTK

Sequences:

>Translated_256_residues
MELKLNKPICFFDLETTGIDIGKDRIVEISIFKVFPNGNKESKTWLVNPTIPIPPQTTAVHGITDEKVANEPTFAELAPL
VHNMIKDSDLAGFNSDRFDIPLLAEELLRAGVDFDMKNKVSVDVQTIFHKMEERTLSAALKFYCGKSLDNAHSAEADTMA
TYEILKAQLDRYPELENDMKSLSEFTTRKRIADFAGMIAFDNDDEEIFTFGKHKGAKVEKVLETEPGYFSWIQNADFPLY
TKKVLTGIKLRKLNTK
>Mature_256_residues
MELKLNKPICFFDLETTGIDIGKDRIVEISIFKVFPNGNKESKTWLVNPTIPIPPQTTAVHGITDEKVANEPTFAELAPL
VHNMIKDSDLAGFNSDRFDIPLLAEELLRAGVDFDMKNKVSVDVQTIFHKMEERTLSAALKFYCGKSLDNAHSAEADTMA
TYEILKAQLDRYPELENDMKSLSEFTTRKRIADFAGMIAFDNDDEEIFTFGKHKGAKVEKVLETEPGYFSWIQNADFPLY
TKKVLTGIKLRKLNTK

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR000014
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 28989; Mature: 28989

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKLNKPICFFDLETTGIDIGKDRIVEISIFKVFPNGNKESKTWLVNPTIPIPPQTTAV
CCEECCCCEEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEECCCCCCCCCCCEE
HGITDEKVANEPTFAELAPLVHNMIKDSDLAGFNSDRFDIPLLAEELLRAGVDFDMKNKV
CCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
SVDVQTIFHKMEERTLSAALKFYCGKSLDNAHSAEADTMATYEILKAQLDRYPELENDMK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
SLSEFTTRKRIADFAGMIAFDNDDEEIFTFGKHKGAKVEKVLETEPGYFSWIQNADFPLY
HHHHHHHHHHHHHHHCEEEECCCCHHEEEECCCCCCHHHHHHHCCCCCEEHHCCCCCCHH
TKKVLTGIKLRKLNTK
HHHHHCCCEEEECCCC
>Mature Secondary Structure
MELKLNKPICFFDLETTGIDIGKDRIVEISIFKVFPNGNKESKTWLVNPTIPIPPQTTAV
CCEECCCCEEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEECCCCCCCCCCCEE
HGITDEKVANEPTFAELAPLVHNMIKDSDLAGFNSDRFDIPLLAEELLRAGVDFDMKNKV
CCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
SVDVQTIFHKMEERTLSAALKFYCGKSLDNAHSAEADTMATYEILKAQLDRYPELENDMK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
SLSEFTTRKRIADFAGMIAFDNDDEEIFTFGKHKGAKVEKVLETEPGYFSWIQNADFPLY
HHHHHHHHHHHHHHHCEEEECCCCHHEEEECCCCCCHHHHHHHCCCCCEEHHCCCCCCHH
TKKVLTGIKLRKLNTK
HHHHHCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]