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The map label for this gene is ycgM [H]

Identifier: 146302713

GI number: 146302713

Start: 6022280

End: 6022891

Strand: Reverse

Name: ycgM [H]

Synonym: Fjoh_4986

Alternate gene names: 146302713

Gene position: 6022891-6022280 (Counterclockwise)

Preceding gene: 146302714

Following gene: 146302712

Centisome position: 98.79

GC content: 32.84

Gene sequence:

>612_bases
ATGAAAATCATTTGTATCGGTAGAAATTATACCAATCATATAGAGGAATTAAAAAACGAGCGTCCGGATGAACCTGTGGT
TTTTATGAAACCGGATTCGGCAGTTTTATTGAAACAGCATCCGTTTGTAATTCCCGAATTTTCTGAAGAAGTTCATCACG
AATTAGAAATAATTGTGAAAATTAACAAAGTAGGAAAGTATATTGAACCTAAGTTTGCGAACAAATATTATGATGATATC
AGTGTAGGTATCGATTTTACTGCCAGGGATTTACAGGATAAATTGAAAGCCAAAGGACTGCCTTGGGAAAAAGCAAAAGC
ATTTGACGGCTCTGCGGTAATTGGAGATTTTTTACCAAAAAGTGATTTTGTTTCGTTAGAAAATCTTACGTTTGAGCTCA
AAAAAAATTCTGAAATCGTTCAAAAAGGAAATACAAGTTTGATGCTTTGGAAAATTGATGAACTGATTTCGTATGTATCG
CAGTTTTTTACGTTAAAAATTGGAGATATTATTTTTACAGGAACACCAGCAGGTGTTGGGCCGGTAAAACCAAATGATGT
TTTGGAAGGCTTTTTAGAAGATAAAAAATTATTCAGAATACAAGTAAAATAA

Upstream 100 bases:

>100_bases
TTAAATACAAAATAAGATTCTGAGTTACTGAGCTTCTATGGTTCTAAGTTTTTTTTCCTTAGCAGCTCAGTAACTTGGTA
TCTCAGTACCTTTAAAAAAA

Downstream 100 bases:

>100_bases
TGGCTTTAAAGTACAATCTTTCGAAAGTGTATGCGCTTTCAGACAATGACCCCGAATTTGTAAACGAAATTCTTAAACTA
TTTGTTACAGAAGTTCCTGA

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKIICIGRNYTNHIEELKNERPDEPVVFMKPDSAVLLKQHPFVIPEFSEEVHHELEIIVKINKVGKYIEPKFANKYYDDI
SVGIDFTARDLQDKLKAKGLPWEKAKAFDGSAVIGDFLPKSDFVSLENLTFELKKNSEIVQKGNTSLMLWKIDELISYVS
QFFTLKIGDIIFTGTPAGVGPVKPNDVLEGFLEDKKLFRIQVK

Sequences:

>Translated_203_residues
MKIICIGRNYTNHIEELKNERPDEPVVFMKPDSAVLLKQHPFVIPEFSEEVHHELEIIVKINKVGKYIEPKFANKYYDDI
SVGIDFTARDLQDKLKAKGLPWEKAKAFDGSAVIGDFLPKSDFVSLENLTFELKKNSEIVQKGNTSLMLWKIDELISYVS
QFFTLKIGDIIFTGTPAGVGPVKPNDVLEGFLEDKKLFRIQVK
>Mature_203_residues
MKIICIGRNYTNHIEELKNERPDEPVVFMKPDSAVLLKQHPFVIPEFSEEVHHELEIIVKINKVGKYIEPKFANKYYDDI
SVGIDFTARDLQDKLKAKGLPWEKAKAFDGSAVIGDFLPKSDFVSLENLTFELKKNSEIVQKGNTSLMLWKIDELISYVS
QFFTLKIGDIIFTGTPAGVGPVKPNDVLEGFLEDKKLFRIQVK

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI66348062, Length=188, Percent_Identity=43.0851063829787, Blast_Score=170, Evalue=9e-43,
Organism=Homo sapiens, GI215422413, Length=188, Percent_Identity=43.0851063829787, Blast_Score=170, Evalue=9e-43,
Organism=Homo sapiens, GI13654274, Length=188, Percent_Identity=43.0851063829787, Blast_Score=169, Evalue=1e-42,
Organism=Homo sapiens, GI156231349, Length=180, Percent_Identity=38.8888888888889, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI40786394, Length=180, Percent_Identity=37.7777777777778, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI1787428, Length=188, Percent_Identity=43.0851063829787, Blast_Score=168, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17557057, Length=194, Percent_Identity=41.2371134020619, Blast_Score=159, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6324161, Length=224, Percent_Identity=35.7142857142857, Blast_Score=128, Evalue=6e-31,
Organism=Drosophila melanogaster, GI28571789, Length=202, Percent_Identity=32.6732673267327, Blast_Score=119, Evalue=9e-28,
Organism=Drosophila melanogaster, GI28572127, Length=200, Percent_Identity=34, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24663695, Length=207, Percent_Identity=28.9855072463768, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23160; Mature: 23160

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIICIGRNYTNHIEELKNERPDEPVVFMKPDSAVLLKQHPFVIPEFSEEVHHELEIIVK
CEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCEECCCHHHHHHHHEEEEEE
INKVGKYIEPKFANKYYDDISVGIDFTARDLQDKLKAKGLPWEKAKAFDGSAVIGDFLPK
EEHHCCCCCCHHCCHHHCCEEECCCCCHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHCCC
SDFVSLENLTFELKKNSEIVQKGNTSLMLWKIDELISYVSQFFTLKIGDIIFTGTPAGVG
CCCEEEEEEEEEECCCCHHHHCCCCEEEEEEHHHHHHHHHHHHEEEECCEEEECCCCCCC
PVKPNDVLEGFLEDKKLFRIQVK
CCCHHHHHHHHHCCCEEEEEEEC
>Mature Secondary Structure
MKIICIGRNYTNHIEELKNERPDEPVVFMKPDSAVLLKQHPFVIPEFSEEVHHELEIIVK
CEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCEECCCHHHHHHHHEEEEEE
INKVGKYIEPKFANKYYDDISVGIDFTARDLQDKLKAKGLPWEKAKAFDGSAVIGDFLPK
EEHHCCCCCCHHCCHHHCCEEECCCCCHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHCCC
SDFVSLENLTFELKKNSEIVQKGNTSLMLWKIDELISYVSQFFTLKIGDIIFTGTPAGVG
CCCEEEEEEEEEECCCCHHHHCCCCEEEEEEHHHHHHHHHHHHEEEECCEEEECCCCCCC
PVKPNDVLEGFLEDKKLFRIQVK
CCCHHHHHHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]