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The map label for this gene is trpD

Identifier: 146302620

GI number: 146302620

Start: 5914960

End: 5915952

Strand: Direct

Name: trpD

Synonym: Fjoh_4893

Alternate gene names: 146302620

Gene position: 5914960-5915952 (Clockwise)

Preceding gene: 146302619

Following gene: 146302621

Centisome position: 97.02

GC content: 35.65

Gene sequence:

>993_bases
ATGAAAACTATATTAAACAAATTAATCAACCACGAAGTGCTTTCTAAAGAAGAAGCAAAAAACGTATTGATTAATATTTC
AAGCGGTCAATACAATCCAAGTCAGATTTCGGCATTTTTGACTGTTTTTATGATGCGAAGCATTACGATTGACGAACTTT
CTGGCTTTCGCGAAGCTTTATTAGAATTATGTATTCGTATCGATTTATCTGCATATAACACAATCGATTTATGCGGAACA
GGCGGTGATGGAAAAGATACCTTTAATATTTCGACTTTAGCCTCTTTTGTAGCGGCAGGAGCTGGAATAAAAGTGGCAAA
ACATGGAAATTACGGTGTTTCTTCTATTTCAGGATCAAGCAATGTAATGGAAAAAATGGGAATTAAATTCAGTAATGATC
CTTCGTTTTTAGAAAAATGCATCGATCAGGCTGGAATCTGTGTTCTGCACGCTCCCCTGTTTCACCCAGCGATGAAAAAC
GTTGGACCAATCAGAAAAGAACTGGCAGTGAAAACTTTCTTTAATATGTTAGGTCCAATGGTAAATCCATCATTTCCACA
AAATCAGCTCGTTGGAGTTTTCAACTTAGAACTGGCAAGAATGTATGCGTATTTATACCAAAATACCAATGTAAATTTCA
CAATCCTGCATTCGCTTGATGGTTATGATGAAATTTCCCTAACCGGGCCAACAAAAATTATTACCAGCCACATGGAAGGA
ATGATAAAACCAGAAGATTTTGGCATTCGTCTTTTATCTCAAACTGAAATTGAAGGCGGAAAAACCATTGAAGAATCAGC
CGAAATTTTCACCAATATTATTTCAGGAAAAGGAAACGAAGCACAGAATAATGTTGTTTGTGCCAATGCAGCAATGGCAA
TTGCAACAGTTACAAAATGTTCTCCTCAAGAAGGATTTGAATTAGCAAAAGAAAGTTTGTTCTCAGGAAAAGGGTTAAAA
GCTTTACAAAAATTACAGGAATTATCACTTTAA

Upstream 100 bases:

>100_bases
GGTCTTTCGCTATTTTAAAACTAAAAAACACAAGAAAAAAATGAATTACAAAGTCAAGGACTTTAAGACCTTTGACTTTA
GACTTTAAGACTAAATTTCA

Downstream 100 bases:

>100_bases
AAAAAGCTTTGTATCAGTATCTTAGAATCTTAGCACCTTAAAAAAATGAATATTTTAGATAAAATAATAATAGATAAAAA
ACGAGAAGTTATTCTAAAGA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKTILNKLINHEVLSKEEAKNVLINISSGQYNPSQISAFLTVFMMRSITIDELSGFREALLELCIRIDLSAYNTIDLCGT
GGDGKDTFNISTLASFVAAGAGIKVAKHGNYGVSSISGSSNVMEKMGIKFSNDPSFLEKCIDQAGICVLHAPLFHPAMKN
VGPIRKELAVKTFFNMLGPMVNPSFPQNQLVGVFNLELARMYAYLYQNTNVNFTILHSLDGYDEISLTGPTKIITSHMEG
MIKPEDFGIRLLSQTEIEGGKTIEESAEIFTNIISGKGNEAQNNVVCANAAMAIATVTKCSPQEGFELAKESLFSGKGLK
ALQKLQELSL

Sequences:

>Translated_330_residues
MKTILNKLINHEVLSKEEAKNVLINISSGQYNPSQISAFLTVFMMRSITIDELSGFREALLELCIRIDLSAYNTIDLCGT
GGDGKDTFNISTLASFVAAGAGIKVAKHGNYGVSSISGSSNVMEKMGIKFSNDPSFLEKCIDQAGICVLHAPLFHPAMKN
VGPIRKELAVKTFFNMLGPMVNPSFPQNQLVGVFNLELARMYAYLYQNTNVNFTILHSLDGYDEISLTGPTKIITSHMEG
MIKPEDFGIRLLSQTEIEGGKTIEESAEIFTNIISGKGNEAQNNVVCANAAMAIATVTKCSPQEGFELAKESLFSGKGLK
ALQKLQELSL
>Mature_330_residues
MKTILNKLINHEVLSKEEAKNVLINISSGQYNPSQISAFLTVFMMRSITIDELSGFREALLELCIRIDLSAYNTIDLCGT
GGDGKDTFNISTLASFVAAGAGIKVAKHGNYGVSSISGSSNVMEKMGIKFSNDPSFLEKCIDQAGICVLHAPLFHPAMKN
VGPIRKELAVKTFFNMLGPMVNPSFPQNQLVGVFNLELARMYAYLYQNTNVNFTILHSLDGYDEISLTGPTKIITSHMEG
MIKPEDFGIRLLSQTEIEGGKTIEESAEIFTNIISGKGNEAQNNVVCANAAMAIATVTKCSPQEGFELAKESLFSGKGLK
ALQKLQELSL

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=289, Percent_Identity=37.0242214532872, Blast_Score=173, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320561, Length=275, Percent_Identity=33.4545454545455, Blast_Score=109, Evalue=6e-25,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_FLAJ1 (A5FA70)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001197211.1
- ProteinModelPortal:   A5FA70
- SMR:   A5FA70
- STRING:   A5FA70
- GeneID:   5094331
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_4893
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   GSADIME
- ProtClustDB:   CLSK913502
- BioCyc:   FJOH376686:FJOH_4893-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35864; Mature: 35864

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTILNKLINHEVLSKEEAKNVLINISSGQYNPSQISAFLTVFMMRSITIDELSGFREAL
CHHHHHHHHHHHHHCHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LELCIRIDLSAYNTIDLCGTGGDGKDTFNISTLASFVAAGAGIKVAKHGNYGVSSISGSS
HHHHHHHCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCCCCCCCCH
NVMEKMGIKFSNDPSFLEKCIDQAGICVLHAPLFHPAMKNVGPIRKELAVKTFFNMLGPM
HHHHHHCCCCCCCHHHHHHHHHHCCEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
VNPSFPQNQLVGVFNLELARMYAYLYQNTNVNFTILHSLDGYDEISLTGPTKIITSHMEG
CCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCHHHHHHHHHC
MIKPEDFGIRLLSQTEIEGGKTIEESAEIFTNIISGKGNEAQNNVVCANAAMAIATVTKC
CCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCC
SPQEGFELAKESLFSGKGLKALQKLQELSL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKTILNKLINHEVLSKEEAKNVLINISSGQYNPSQISAFLTVFMMRSITIDELSGFREAL
CHHHHHHHHHHHHHCHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LELCIRIDLSAYNTIDLCGTGGDGKDTFNISTLASFVAAGAGIKVAKHGNYGVSSISGSS
HHHHHHHCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCCCCCCCCH
NVMEKMGIKFSNDPSFLEKCIDQAGICVLHAPLFHPAMKNVGPIRKELAVKTFFNMLGPM
HHHHHHCCCCCCCHHHHHHHHHHCCEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
VNPSFPQNQLVGVFNLELARMYAYLYQNTNVNFTILHSLDGYDEISLTGPTKIITSHMEG
CCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCHHHHHHHHHC
MIKPEDFGIRLLSQTEIEGGKTIEESAEIFTNIISGKGNEAQNNVVCANAAMAIATVTKC
CCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCC
SPQEGFELAKESLFSGKGLKALQKLQELSL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA