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The map label for this gene is yrkH [H]

Identifier: 146302608

GI number: 146302608

Start: 5903499

End: 5904914

Strand: Direct

Name: yrkH [H]

Synonym: Fjoh_4881

Alternate gene names: 146302608

Gene position: 5903499-5904914 (Clockwise)

Preceding gene: 146302599

Following gene: 146302609

Centisome position: 96.83

GC content: 38.56

Gene sequence:

>1416_bases
ATGAAAATAGAACAAATTTACACCGGATGCTTAGCACAAGGTGCATATTATATCACTTCAAATGGCGAAGCGGCCATTAT
TGATCCGCTTAGAGAAATACAGCCTTATTTAGATCGTTTAGAACGCGACGGAGTAAAGCTGCAATATATTTTTGAAACGC
ATTTTCACGCTGATTTCGTTTCAGGACACGTTGATTTAAGCAAAGAAACCGGAGCGCCAATTGTTTACGGTCCAAATGCT
GCCTGCGAATTTGACTGCATTTCTGCAAAAGACGGACAGGAATTTAAAGTTGGAAAAGTAACGATCAAAGTTTTGCACAC
TCCGGGACATACTATGGAAAGCACGACTTTTTTACTTATTGACGAAAATGGAAAAGATCACGCTATTTTCTCTGGAGATA
CTTTATTTATTGGCGATGTAGGCCGTCCGGATTTAGCTCAAAAAGCTTCTGGAATGACTCAGGATCAATTGGCAGGAATT
TTATTTCATTCGTTAAGAGATAAAATCATGACGCTGGCTGATGATGTAATTGTATATCCTGCTCATGGTGCGGGAAGTGC
CTGCGGAAAAAACATGAGTAAAGAAACGGTTTCGACTATTGGAAATCAAAAAGCAACAAATTATGCTTTGCGCGCTGATA
TGACCGAAGCAGAATTTATAAAAGAAGTTACTGACGGATTATTGCCTCCTCCGGCCTATTTTAGTATGAACGTTGCCATG
AACAAACAAGGTTACGAAAGTTTTGAAACGGTCTTGCATAATGGAATGAAGTCTATTAAAGCAGAAGAATTCGAGGCTGT
GGCCGAAGAAACTGGAGCTTTAATTTTAGATACTCGTAAAAGCGGTGATTTTGCTAAAGGATTTATTCCGCAGTCAATTA
ATATAGGAATCAACGGTGATTTTGCACCGTGGGTTGGAACTTTAATTGGAGACGTAAAACAACCTATTATATTAGTAACC
GAAGCTGGCTTAGAAGAAGAAACTGTTACACGCTTAAGCCGTGTAGGTTTTGACTCAATTATCGGGCATCTTGAAGGCGG
TTTTGAAGCCTGGGAAAAAGCAGGTTTTGAAATTGATACGGTAAACCGAATTTCAGCAGAAGAATTTGCCGGAAAATTTA
ATATCAAAGAAGACAAGGTTATTGATGTTCGTAAGGAAACAGAATATGAAGCAGAGCATATCGAAGATGCTTACAGCAAA
CCTCTAGCTTATATTAATGACTGGGTAAAAGATATTAACCCAAATGAACATTTTTTCCTGCATTGTGCCGGCGGTTACCG
CAGTATGATTGCGGCTTCTATTCTTCAAGCACGCGGATTTAGAAATTTTTCTGAAGTTGACGGCGGTTTCGGAGCAATCT
CAAAAACAAATATTCCAAAATCAGATTTTGTTTGTCAAAGCAAAATATTAAAATAA

Upstream 100 bases:

>100_bases
CGCATTATTTTACACAAAAACCTAATTTCTGTAACATTAGTCACCTATTTTTTTAAAAAACAAAACTACCTTTGTATCCC
ATCATTTTACAACACCTATC

Downstream 100 bases:

>100_bases
TTTTTGAGGTACAGAGGTTCAAAGGTGCAAAGCGACAAAGTTTTCCCTTTGAACCTCTGTACCTTTGAACCTTTGAACCT
AAAAAATATGCTAGAAATTT

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKIEQIYTGCLAQGAYYITSNGEAAIIDPLREIQPYLDRLERDGVKLQYIFETHFHADFVSGHVDLSKETGAPIVYGPNA
ACEFDCISAKDGQEFKVGKVTIKVLHTPGHTMESTTFLLIDENGKDHAIFSGDTLFIGDVGRPDLAQKASGMTQDQLAGI
LFHSLRDKIMTLADDVIVYPAHGAGSACGKNMSKETVSTIGNQKATNYALRADMTEAEFIKEVTDGLLPPPAYFSMNVAM
NKQGYESFETVLHNGMKSIKAEEFEAVAEETGALILDTRKSGDFAKGFIPQSINIGINGDFAPWVGTLIGDVKQPIILVT
EAGLEEETVTRLSRVGFDSIIGHLEGGFEAWEKAGFEIDTVNRISAEEFAGKFNIKEDKVIDVRKETEYEAEHIEDAYSK
PLAYINDWVKDINPNEHFFLHCAGGYRSMIAASILQARGFRNFSEVDGGFGAISKTNIPKSDFVCQSKILK

Sequences:

>Translated_471_residues
MKIEQIYTGCLAQGAYYITSNGEAAIIDPLREIQPYLDRLERDGVKLQYIFETHFHADFVSGHVDLSKETGAPIVYGPNA
ACEFDCISAKDGQEFKVGKVTIKVLHTPGHTMESTTFLLIDENGKDHAIFSGDTLFIGDVGRPDLAQKASGMTQDQLAGI
LFHSLRDKIMTLADDVIVYPAHGAGSACGKNMSKETVSTIGNQKATNYALRADMTEAEFIKEVTDGLLPPPAYFSMNVAM
NKQGYESFETVLHNGMKSIKAEEFEAVAEETGALILDTRKSGDFAKGFIPQSINIGINGDFAPWVGTLIGDVKQPIILVT
EAGLEEETVTRLSRVGFDSIIGHLEGGFEAWEKAGFEIDTVNRISAEEFAGKFNIKEDKVIDVRKETEYEAEHIEDAYSK
PLAYINDWVKDINPNEHFFLHCAGGYRSMIAASILQARGFRNFSEVDGGFGAISKTNIPKSDFVCQSKILK
>Mature_471_residues
MKIEQIYTGCLAQGAYYITSNGEAAIIDPLREIQPYLDRLERDGVKLQYIFETHFHADFVSGHVDLSKETGAPIVYGPNA
ACEFDCISAKDGQEFKVGKVTIKVLHTPGHTMESTTFLLIDENGKDHAIFSGDTLFIGDVGRPDLAQKASGMTQDQLAGI
LFHSLRDKIMTLADDVIVYPAHGAGSACGKNMSKETVSTIGNQKATNYALRADMTEAEFIKEVTDGLLPPPAYFSMNVAM
NKQGYESFETVLHNGMKSIKAEEFEAVAEETGALILDTRKSGDFAKGFIPQSINIGINGDFAPWVGTLIGDVKQPIILVT
EAGLEEETVTRLSRVGFDSIIGHLEGGFEAWEKAGFEIDTVNRISAEEFAGKFNIKEDKVIDVRKETEYEAEHIEDAYSK
PLAYINDWVKDINPNEHFFLHCAGGYRSMIAASILQARGFRNFSEVDGGFGAISKTNIPKSDFVCQSKILK

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=224, Percent_Identity=31.25, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1787158, Length=212, Percent_Identity=29.2452830188679, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221330176, Length=243, Percent_Identity=28.8065843621399, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 51758; Mature: 51758

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEQIYTGCLAQGAYYITSNGEAAIIDPLREIQPYLDRLERDGVKLQYIFETHFHADFV
CCHHHHHHHHHHCCEEEEECCCCEEEECHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHH
SGHVDLSKETGAPIVYGPNAACEFDCISAKDGQEFKVGKVTIKVLHTPGHTMESTTFLLI
CCCEEECCCCCCCEEECCCCCCEEEEECCCCCCCEEEEEEEEEEEECCCCCCCCEEEEEE
DENGKDHAIFSGDTLFIGDVGRPDLAQKASGMTQDQLAGILFHSLRDKIMTLADDVIVYP
ECCCCCCEEEECCEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEE
AHGAGSACGKNMSKETVSTIGNQKATNYALRADMTEAEFIKEVTDGLLPPPAYFSMNVAM
CCCCCHHHCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEE
NKQGYESFETVLHNGMKSIKAEEFEAVAEETGALILDTRKSGDFAKGFIPQSINIGINGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCCCCEEEECCCCC
FAPWVGTLIGDVKQPIILVTEAGLEEETVTRLSRVGFDSIIGHLEGGFEAWEKAGFEIDT
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCEEEC
VNRISAEEFAGKFNIKEDKVIDVRKETEYEAEHIEDAYSKPLAYINDWVKDINPNEHFFL
CCCCCHHHHCCCCCCCCCCEEECHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEE
HCAGGYRSMIAASILQARGFRNFSEVDGGFGAISKTNIPKSDFVCQSKILK
EECCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKIEQIYTGCLAQGAYYITSNGEAAIIDPLREIQPYLDRLERDGVKLQYIFETHFHADFV
CCHHHHHHHHHHCCEEEEECCCCEEEECHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHH
SGHVDLSKETGAPIVYGPNAACEFDCISAKDGQEFKVGKVTIKVLHTPGHTMESTTFLLI
CCCEEECCCCCCCEEECCCCCCEEEEECCCCCCCEEEEEEEEEEEECCCCCCCCEEEEEE
DENGKDHAIFSGDTLFIGDVGRPDLAQKASGMTQDQLAGILFHSLRDKIMTLADDVIVYP
ECCCCCCEEEECCEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEE
AHGAGSACGKNMSKETVSTIGNQKATNYALRADMTEAEFIKEVTDGLLPPPAYFSMNVAM
CCCCCHHHCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEE
NKQGYESFETVLHNGMKSIKAEEFEAVAEETGALILDTRKSGDFAKGFIPQSINIGINGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCCCCEEEECCCCC
FAPWVGTLIGDVKQPIILVTEAGLEEETVTRLSRVGFDSIIGHLEGGFEAWEKAGFEIDT
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCEEEC
VNRISAEEFAGKFNIKEDKVIDVRKETEYEAEHIEDAYSKPLAYINDWVKDINPNEHFFL
CCCCCHHHHCCCCCCCCCCEEECHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEE
HCAGGYRSMIAASILQARGFRNFSEVDGGFGAISKTNIPKSDFVCQSKILK
EECCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]