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The map label for this gene is tatD [H]

Identifier: 146302468

GI number: 146302468

Start: 5732183

End: 5732980

Strand: Reverse

Name: tatD [H]

Synonym: Fjoh_4741

Alternate gene names: 146302468

Gene position: 5732980-5732183 (Counterclockwise)

Preceding gene: 146302469

Following gene: 146302467

Centisome position: 94.03

GC content: 40.6

Gene sequence:

>798_bases
ATGAATTACATAGACATAGGTATCAACCTAACCAACAAACAATTCCAAAACGACATAGACGATGTTGTACAAGACGCGAT
TGACGCCGATGTATCGCAAATGATCCTAACGGGAACAAGCGTGCGAAACAGCGAAGCATCATTAGAAATCGCAAAACAAT
ATCCGGGAGTATTATATGCTACAGCCGGAATTCACCCGCATGATGCGAAGAGTTTTGATGCGCAGAGTATTTCGAAACTC
AGGAAATTATTAGAACTGAAACAAGTCGTTTCGGTTGGCGAATGCGGACTCGATTTTGATCGTGACTTTTCGCCCCGAAA
CAAACAGGAAGAATGTTACAAAGTTCAATTAGAATTGGCGATTGAAGTACAGAAACCTTTGTTTTTGCACGAAAGAAGCG
CTTTTAATTCATTTATGAATATCACAAAAGACTATCTGCCAAAACTGCCTAAAGCCGTTGTGCATTGTTTTACGGGAACT
TTGCAGGAAGCCAAAACCTATCTCGATAACGGATTTTATCTGGGTTTTACAGGAGCGATTTCAGATGTTAAACGTTTCAG
CCATTTAAAAGAAGTCATTCAGTACGTACCGCTCGACCGAATGATGATTGAAACCGATGCGCCGTTTATGCTTCCTAAAA
ATGTCCCGAACAGCCTTTTAAAAAAATACCACGAACGCCGTTGCGAACCTGCTTTTCTACCGTATGTTGCTGGAACTATT
GCACAGTTTAAAGGAATTACTTTGGCTAAAGTCGCGGAGGAAACAACTAGGAATTCTAAATGCTTTTTTGGGATTTAG

Upstream 100 bases:

>100_bases
ACGATTAAAAAATCACAAAAAAATAAATAATAAAGGTCTCAAAGAGAGAAAAAAAAACTTAGCACCTTAGCCTCTCAGAA
CCTTAGCACCTTAAAAAAAA

Downstream 100 bases:

>100_bases
ATTTTAATTTATAAAGATTATTTGTTGGCTTTTAAATCAGGGGTTTGTACTTGGTTTGAAGGCTTTTTGTTTGTATATAT
TTGGAAATATTCAATTTCTA

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MNYIDIGINLTNKQFQNDIDDVVQDAIDADVSQMILTGTSVRNSEASLEIAKQYPGVLYATAGIHPHDAKSFDAQSISKL
RKLLELKQVVSVGECGLDFDRDFSPRNKQEECYKVQLELAIEVQKPLFLHERSAFNSFMNITKDYLPKLPKAVVHCFTGT
LQEAKTYLDNGFYLGFTGAISDVKRFSHLKEVIQYVPLDRMMIETDAPFMLPKNVPNSLLKKYHERRCEPAFLPYVAGTI
AQFKGITLAKVAEETTRNSKCFFGI

Sequences:

>Translated_265_residues
MNYIDIGINLTNKQFQNDIDDVVQDAIDADVSQMILTGTSVRNSEASLEIAKQYPGVLYATAGIHPHDAKSFDAQSISKL
RKLLELKQVVSVGECGLDFDRDFSPRNKQEECYKVQLELAIEVQKPLFLHERSAFNSFMNITKDYLPKLPKAVVHCFTGT
LQEAKTYLDNGFYLGFTGAISDVKRFSHLKEVIQYVPLDRMMIETDAPFMLPKNVPNSLLKKYHERRCEPAFLPYVAGTI
AQFKGITLAKVAEETTRNSKCFFGI
>Mature_265_residues
MNYIDIGINLTNKQFQNDIDDVVQDAIDADVSQMILTGTSVRNSEASLEIAKQYPGVLYATAGIHPHDAKSFDAQSISKL
RKLLELKQVVSVGECGLDFDRDFSPRNKQEECYKVQLELAIEVQKPLFLHERSAFNSFMNITKDYLPKLPKAVVHCFTGT
LQEAKTYLDNGFYLGFTGAISDVKRFSHLKEVIQYVPLDRMMIETDAPFMLPKNVPNSLLKKYHERRCEPAFLPYVAGTI
AQFKGITLAKVAEETTRNSKCFFGI

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=224, Percent_Identity=35.7142857142857, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI225903439, Length=182, Percent_Identity=35.7142857142857, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI225903424, Length=209, Percent_Identity=31.1004784688995, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI226061853, Length=279, Percent_Identity=24.7311827956989, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI110349730, Length=275, Percent_Identity=24.7272727272727, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI110349734, Length=275, Percent_Identity=24.7272727272727, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI226061614, Length=267, Percent_Identity=24.3445692883895, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI226061595, Length=235, Percent_Identity=23.4042553191489, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI48994985, Length=261, Percent_Identity=41.7624521072797, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=28.4046692607004, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082439, Length=212, Percent_Identity=32.5471698113208, Blast_Score=102, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17559024, Length=274, Percent_Identity=40.5109489051095, Blast_Score=213, Evalue=7e-56,
Organism=Caenorhabditis elegans, GI71980746, Length=271, Percent_Identity=28.4132841328413, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17565396, Length=223, Percent_Identity=30.4932735426009, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17543026, Length=236, Percent_Identity=28.8135593220339, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24648690, Length=282, Percent_Identity=38.2978723404255, Blast_Score=196, Evalue=1e-50,
Organism=Drosophila melanogaster, GI221330018, Length=229, Percent_Identity=35.3711790393013, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24586117, Length=260, Percent_Identity=31.1538461538462, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29958; Mature: 29958

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYIDIGINLTNKQFQNDIDDVVQDAIDADVSQMILTGTSVRNSEASLEIAKQYPGVLYA
CCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEE
TAGIHPHDAKSFDAQSISKLRKLLELKQVVSVGECGLDFDRDFSPRNKQEECYKVQLELA
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHEEEEEEE
IEVQKPLFLHERSAFNSFMNITKDYLPKLPKAVVHCFTGTLQEAKTYLDNGFYLGFTGAI
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHH
SDVKRFSHLKEVIQYVPLDRMMIETDAPFMLPKNVPNSLLKKYHERRCEPAFLPYVAGTI
HHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
AQFKGITLAKVAEETTRNSKCFFGI
HHHCCCHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MNYIDIGINLTNKQFQNDIDDVVQDAIDADVSQMILTGTSVRNSEASLEIAKQYPGVLYA
CCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEE
TAGIHPHDAKSFDAQSISKLRKLLELKQVVSVGECGLDFDRDFSPRNKQEECYKVQLELA
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHEEEEEEE
IEVQKPLFLHERSAFNSFMNITKDYLPKLPKAVVHCFTGTLQEAKTYLDNGFYLGFTGAI
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHH
SDVKRFSHLKEVIQYVPLDRMMIETDAPFMLPKNVPNSLLKKYHERRCEPAFLPYVAGTI
HHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
AQFKGITLAKVAEETTRNSKCFFGI
HHHCCCHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]