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The map label for this gene is lytT [H]

Identifier: 146302401

GI number: 146302401

Start: 5656475

End: 5657239

Strand: Direct

Name: lytT [H]

Synonym: Fjoh_4674

Alternate gene names: 146302401

Gene position: 5656475-5657239 (Clockwise)

Preceding gene: 146302399

Following gene: 146302402

Centisome position: 92.78

GC content: 32.16

Gene sequence:

>765_bases
ATGAGAATTGCCATTGTCGAAGACGAATATCTTGCTTCCAGTTATCTAAAATCGATTTTAGAGCAGCAGGAAATTTTACA
GATTGCAGAAATTACAGTTTTAAAATCTGTAAAAGAAGCCGTCGACTTTTTTAAACAAAACAATGTCGATCTCGCTTTTA
TGGACATTCACCTTGGCGATGGAAAAAGTCTTGAGATTTTTGAAAAAACCACAATCTCCTGCCCTGTTATTTTTGTTACG
GCTTATGATTCTTACGCTATCTCGGTTTTCAAACACTTTACCATAGATTATCTTTTAAAACCTTTTGAAGAACAGGAATT
ATTAGAAGCCTTATTCAAATTCAAAAAAATAAAAGAGAGTTTTAATACCGATGCTGCAGTGCGGTCATTAGTCGCATTAG
AAAATCCCGAAACAAACAAAATACAGCGTCATTTTTTAGTAAACCACGGATATAAGCTAATTTCGGTAAACGAGTCTGAA
ATCACCTATTTTGCAGCATCCGGAAAGCATTTGTTTATCTATGTAAAATCTGGAAACAGTTATTTGTACAATAATACACT
TACAGACATCATAAACAGCCTCGATCCGTTTATTTTTTTTAAAGTAAACAGAAAATATATCGTAAGCCGAAATATTATAA
AAGAAGTCGTAAAACATTCAAATCAAAAAATCGAATTAATTCTTACGGTTCCACCAGTCGAAGATGACCCTATTATGATT
AGCAAAAAAGAAATAAATAATTTCAAAAACTGGCTTGATCAATAA

Upstream 100 bases:

>100_bases
ATTAAAAACATATTGCAAAAAATCCAGAGACAATTATATTTGCACAACCATTAAGAACTTCATTTTATTGAATGAAACTT
TTTAACATCAGCCAAGAATA

Downstream 100 bases:

>100_bases
TTTTCAGCTTCAATTTCTCTTAAATTTTGGCTTTTGCCCAAAATCAAAAAACTGAATTATTCATAATTTAGGAATCAAAA
TCTGCCTAAAAACTGTCAAA

Product: LytTR family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRIAIVEDEYLASSYLKSILEQQEILQIAEITVLKSVKEAVDFFKQNNVDLAFMDIHLGDGKSLEIFEKTTISCPVIFVT
AYDSYAISVFKHFTIDYLLKPFEEQELLEALFKFKKIKESFNTDAAVRSLVALENPETNKIQRHFLVNHGYKLISVNESE
ITYFAASGKHLFIYVKSGNSYLYNNTLTDIINSLDPFIFFKVNRKYIVSRNIIKEVVKHSNQKIELILTVPPVEDDPIMI
SKKEINNFKNWLDQ

Sequences:

>Translated_254_residues
MRIAIVEDEYLASSYLKSILEQQEILQIAEITVLKSVKEAVDFFKQNNVDLAFMDIHLGDGKSLEIFEKTTISCPVIFVT
AYDSYAISVFKHFTIDYLLKPFEEQELLEALFKFKKIKESFNTDAAVRSLVALENPETNKIQRHFLVNHGYKLISVNESE
ITYFAASGKHLFIYVKSGNSYLYNNTLTDIINSLDPFIFFKVNRKYIVSRNIIKEVVKHSNQKIELILTVPPVEDDPIMI
SKKEINNFKNWLDQ
>Mature_254_residues
MRIAIVEDEYLASSYLKSILEQQEILQIAEITVLKSVKEAVDFFKQNNVDLAFMDIHLGDGKSLEIFEKTTISCPVIFVT
AYDSYAISVFKHFTIDYLLKPFEEQELLEALFKFKKIKESFNTDAAVRSLVALENPETNKIQRHFLVNHGYKLISVNESE
ITYFAASGKHLFIYVKSGNSYLYNNTLTDIINSLDPFIFFKVNRKYIVSRNIIKEVVKHSNQKIELILTVPPVEDDPIMI
SKKEINNFKNWLDQ

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=219, Percent_Identity=26.4840182648402, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082052, Length=240, Percent_Identity=23.3333333333333, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 29421; Mature: 29421

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAIVEDEYLASSYLKSILEQQEILQIAEITVLKSVKEAVDFFKQNNVDLAFMDIHLGD
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECC
GKSLEIFEKTTISCPVIFVTAYDSYAISVFKHFTIDYLLKPFEEQELLEALFKFKKIKES
CCEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FNTDAAVRSLVALENPETNKIQRHFLVNHGYKLISVNESEITYFAASGKHLFIYVKSGNS
CCCHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEECCCEEEEEEECCCEEEEEEECCCC
YLYNNTLTDIINSLDPFIFFKVNRKYIVSRNIIKEVVKHSNQKIELILTVPPVEDDPIMI
EEECCHHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEE
SKKEINNFKNWLDQ
EHHHHHHHHHHHCC
>Mature Secondary Structure
MRIAIVEDEYLASSYLKSILEQQEILQIAEITVLKSVKEAVDFFKQNNVDLAFMDIHLGD
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECC
GKSLEIFEKTTISCPVIFVTAYDSYAISVFKHFTIDYLLKPFEEQELLEALFKFKKIKES
CCEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FNTDAAVRSLVALENPETNKIQRHFLVNHGYKLISVNESEITYFAASGKHLFIYVKSGNS
CCCHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEECCCEEEEEEECCCEEEEEEECCCC
YLYNNTLTDIINSLDPFIFFKVNRKYIVSRNIIKEVVKHSNQKIELILTVPPVEDDPIMI
EEECCHHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEE
SKKEINNFKNWLDQ
EHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]