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The map label for this gene is degU [H]

Identifier: 146302355

GI number: 146302355

Start: 5594601

End: 5595260

Strand: Direct

Name: degU [H]

Synonym: Fjoh_4628

Alternate gene names: 146302355

Gene position: 5594601-5595260 (Clockwise)

Preceding gene: 146302354

Following gene: 146302356

Centisome position: 91.76

GC content: 35.15

Gene sequence:

>660_bases
ATGAGTAATATCATTCGTGTAGTATTGGCAGATGACCATGTTTTTGTTAGAGACGGAATCAAATCTTTACTGGAAAACGA
AGCAAACATAGAGGTTGTTGGTGAAGCAATTGACGGTGCAGATGCTCTGGAAGTGGTTACAGCAACAAAACCCGACTTAC
TTATAGTAGATATTCGTATGCCAAACTTAACGGGCATCGAGGTAGTAGAAAAACTTAGAAGCGAGAATAATAACGTAAAA
ATCATTATGCTTTCGATGCACGAATCAGAAGAGTATGTTTTGAAATCTATAAAAGCCGGTGCCGACGGTTATTTACTAAA
AGGTTCATCAAAAGAAGAATTTTTAAAAGCTCTTCATGCCGTTTCTTCAGGCGGTAAGTATTTCAGCGGTGATATTTCTT
CTATTTTAATAAGTCAATTAACAAATTCGACTGCATCTTTAGAACCTAAACAAACTTTAGGTGAAGAAATGATGATTACC
AAAAGAGAAAAAGAAATCCTGACACTTCTTTTATCAGGAAAAGGAAATAAAGAAATTGCCGAAGCTCTTGAAATTAGTAA
AAGAACTGCCGAAGTGCATCGTTTTAACCTGATGAAAAAACTGAAAGTTAAAAACCTTATGGAACTTTCGAACAAAGCGG
CTGAGTATTCTTTAATCTAA

Upstream 100 bases:

>100_bases
ATTTCAAAAATTTGGAATTTTAAATAAAAAAAGTACGTATATTAGCATCTTCTTTTTAGATGAATATACGTAAAAATTCA
GAATCAAAATTAAGTAAACT

Downstream 100 bases:

>100_bases
AAAATACGTATAAATACGTAATTATTTTTCAAAAACTGCGTTTTAGCAGGTTTTAACTAAGTTATAGTACTTATTTTTAC
ATAAAAATATAAGTGCTATG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSNIIRVVLADDHVFVRDGIKSLLENEANIEVVGEAIDGADALEVVTATKPDLLIVDIRMPNLTGIEVVEKLRSENNNVK
IIMLSMHESEEYVLKSIKAGADGYLLKGSSKEEFLKALHAVSSGGKYFSGDISSILISQLTNSTASLEPKQTLGEEMMIT
KREKEILTLLLSGKGNKEIAEALEISKRTAEVHRFNLMKKLKVKNLMELSNKAAEYSLI

Sequences:

>Translated_219_residues
MSNIIRVVLADDHVFVRDGIKSLLENEANIEVVGEAIDGADALEVVTATKPDLLIVDIRMPNLTGIEVVEKLRSENNNVK
IIMLSMHESEEYVLKSIKAGADGYLLKGSSKEEFLKALHAVSSGGKYFSGDISSILISQLTNSTASLEPKQTLGEEMMIT
KREKEILTLLLSGKGNKEIAEALEISKRTAEVHRFNLMKKLKVKNLMELSNKAAEYSLI
>Mature_218_residues
SNIIRVVLADDHVFVRDGIKSLLENEANIEVVGEAIDGADALEVVTATKPDLLIVDIRMPNLTGIEVVEKLRSENNNVKI
IMLSMHESEEYVLKSIKAGADGYLLKGSSKEEFLKALHAVSSGGKYFSGDISSILISQLTNSTASLEPKQTLGEEMMITK
REKEILTLLLSGKGNKEIAEALEISKRTAEVHRFNLMKKLKVKNLMELSNKAAEYSLI

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=216, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1790102, Length=209, Percent_Identity=36.8421052631579, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1788521, Length=205, Percent_Identity=34.6341463414634, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787473, Length=187, Percent_Identity=36.8983957219251, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788712, Length=202, Percent_Identity=30.1980198019802, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1786747, Length=213, Percent_Identity=27.2300469483568, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787277, Length=138, Percent_Identity=34.7826086956522, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI87082052, Length=104, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788546, Length=221, Percent_Identity=28.0542986425339, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24129; Mature: 23998

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIIRVVLADDHVFVRDGIKSLLENEANIEVVGEAIDGADALEVVTATKPDLLIVDIRM
CCCEEEEEEECCCEEHHHHHHHHHCCCCCEEEEEECCCCCCHHEEEECCCCCEEEEEEEC
PNLTGIEVVEKLRSENNNVKIIMLSMHESEEYVLKSIKAGADGYLLKGSSKEEFLKALHA
CCCCHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHH
VSSGGKYFSGDISSILISQLTNSTASLEPKQTLGEEMMITKREKEILTLLLSGKGNKEIA
HHCCCCEECCHHHHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHHHEEHEECCCCCHHHH
EALEISKRTAEVHRFNLMKKLKVKNLMELSNKAAEYSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNIIRVVLADDHVFVRDGIKSLLENEANIEVVGEAIDGADALEVVTATKPDLLIVDIRM
CCEEEEEEECCCEEHHHHHHHHHCCCCCEEEEEECCCCCCHHEEEECCCCCEEEEEEEC
PNLTGIEVVEKLRSENNNVKIIMLSMHESEEYVLKSIKAGADGYLLKGSSKEEFLKALHA
CCCCHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHH
VSSGGKYFSGDISSILISQLTNSTASLEPKQTLGEEMMITKREKEILTLLLSGKGNKEIA
HHCCCCEECCHHHHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHHHEEHEECCCCCHHHH
EALEISKRTAEVHRFNLMKKLKVKNLMELSNKAAEYSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]