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The map label for this gene is nahA [H]

Identifier: 146302283

GI number: 146302283

Start: 5504408

End: 5506474

Strand: Reverse

Name: nahA [H]

Synonym: Fjoh_4556

Alternate gene names: 146302283

Gene position: 5506474-5504408 (Counterclockwise)

Preceding gene: 146302284

Following gene: 146302282

Centisome position: 90.32

GC content: 34.88

Gene sequence:

>2067_bases
ATGAAATATCTATTTGTACTACTATTAGCAGGTGTAACGGCAAATGCTCAAATGCAAAAAGAACAGCTGAACCTTATGCC
CTGGCCTCAAAATGTTGTCGTAAACGACGGAAATTTTACATTAACTAAAAACTTTAAAGTAAATATTTCTGGAAATCCTG
ATTCAAGGATTTTTGGAGGAGTAACTCGTTTTTTACGCCGATTAGATGGTAGAACAGGTATTTTTTTTGAACAAGGTTTT
ATTACCAAACTTAATGAGTTTCCAAATGCAGAATTACAGATTAACTGTACTAAAAATGGAAAAATAGGTTTATATGAAGA
TGAAAGCTACAGCTTAGATGTTAAAGCAAACAAAATTACAATTAATGCAACCAGCGATTTAGGAGCTTTACATGGACTGG
AAACGTTATTGCAGCTGCTTCAAAACGACAGCAAAAAATTCTATTTCCCTGTTTCTCAAATCTCAGACTTTCCAAGATTT
ACCTGGAGAGGTTTAATGCTTGATGCTTCGAGACATTTTCAGCCGGTAGATGTAGTGAAAAGAAATCTGGATGCATTGGC
AGCAATGAAAATGAATGTTTTCCACTGGCATTTAGTAGACGATCAAGGCTGGAGAATTGAAACTAAAAAACATCCAAAAC
TAATAGAACTGGCTTCGGATGGATTATATTACACACAAGAGGAAATTAGAAATATCGTAAAATATGCCGATGAGCGCGGT
ATTTTAATTGTTCCGGAAATAGACGTTCCGGGTCATGGATCTGCAATACTTACTGCTTACCCTGAAATTGGAAGCAAAGT
GATTACATTGACCGGAGGAACTTCTGAAAAAAATATTCAAGGTACGGCAATCTCTACCTATAGAATTGAAAGAAATGCAG
GTATATTTTCGCCTACATTAGATCCTTCAAATCCTAAAACGTATAAAATATTAAGTGAACTTTTTGATGAGGTATGCCCG
TTATTTCCCGGAGCTTATTTTCACATTGGGGGTGACGAAAATGAAGGGAAAGACTGGGATGCCAATCCAAAAATCCAGGA
GTTCAAGAAAAAACATAATTTAAAAACCAACCATGAACTGCAGACTTATTTTACTATGCAGTTAGCCCCAATGCTTAAAA
AACATGGAAAACAATTAATGGGCTGGGAAGAAATTTTAACCAAAGATCTTTCTAAAGAAGCAATTGTACATTCGTGGAGA
GGTCCAAATGAAGGAATGGTTGCAGGGCAGTCATTAGTTGATGCAGTTAAAAAAGGATATAAAACAGTATTATCAAACGG
ATTTTATATTGATTTAATGTATCCAGTAGCAAGTCATTATTTAAATGATCCTATGCCAAAAGGAGCCGATTTATCTGCAG
AAGAAAAAGCAAGAATTTTGGGTGGAGAAGCTACAATGTGGACAGAACTTGCCACGCCGGAAACATTTGATTCAAGAGTT
TGGCCAAGAACAGCAGCAATTGCAGAAAGATTATGGTCTGCTGAGAATATTACAGATGTTGCTAATATGCGTAAACGTCT
TGAAAGCGTATCATTTAGATTAGAAGAATTAGGATTAACACATATTAAAAACAAAGCCGTAATTCTTAGAAATATTGCGA
ATAACCAGAATATTAAATCTGTTAATGAATTTACAAATGTTTGTGAACCATTAAAAGGATATACAAGAAATAAAGGAGGA
ACTGAATATCAAATGTATTCTCCGTTTACACTTTTTGCAGATGCCTGTACTCCGGATGCAAAAGATTCTCTGGCTTTTGA
TGAAGCCGTGAGCCAATATCTGGCAAATAAATCAGCAGATAACAAAGCAAAAGTGGCAGCATTTTTCAATAAATGGATTG
CAGTTAATAAAGGATTAGTTGAATTAAGTGCCAATGCGCCTTTAGTACAGCCAATTCTGCCTTTATCTAAAAAATTAAGC
GACGCATCGCAAGAATTGCTGCTTGTATTAGATAATAAATCGACTTTAAAAACAGCCGATTTAAAAACCTTAATAGAACA
ATGTAATACAAAAGATCATGCTGACGTAGAGTTGTCAGTTTATGAAAGTTTAAAGAAACTAATTTAG

Upstream 100 bases:

>100_bases
CTCGCTATAGGTGAGGTAAAGCAGAAGTCATTCTGAGTTTTGTTTTTTATCTAATTTCTAAAGATGCTTTTTTAGAAGTA
TCGAACCAAAAAAAAATAAA

Downstream 100 bases:

>100_bases
AATTTTGGTTGAGTTAGTGTTTAGTAGTTACCATTGATTTAGTCTTTAATTATCTCTGCCGAATTCCCCGGTAGAGATAG
TTATGGCTATCATTCCTGAA

Product: beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 688; Mature: 688

Protein sequence:

>688_residues
MKYLFVLLLAGVTANAQMQKEQLNLMPWPQNVVVNDGNFTLTKNFKVNISGNPDSRIFGGVTRFLRRLDGRTGIFFEQGF
ITKLNEFPNAELQINCTKNGKIGLYEDESYSLDVKANKITINATSDLGALHGLETLLQLLQNDSKKFYFPVSQISDFPRF
TWRGLMLDASRHFQPVDVVKRNLDALAAMKMNVFHWHLVDDQGWRIETKKHPKLIELASDGLYYTQEEIRNIVKYADERG
ILIVPEIDVPGHGSAILTAYPEIGSKVITLTGGTSEKNIQGTAISTYRIERNAGIFSPTLDPSNPKTYKILSELFDEVCP
LFPGAYFHIGGDENEGKDWDANPKIQEFKKKHNLKTNHELQTYFTMQLAPMLKKHGKQLMGWEEILTKDLSKEAIVHSWR
GPNEGMVAGQSLVDAVKKGYKTVLSNGFYIDLMYPVASHYLNDPMPKGADLSAEEKARILGGEATMWTELATPETFDSRV
WPRTAAIAERLWSAENITDVANMRKRLESVSFRLEELGLTHIKNKAVILRNIANNQNIKSVNEFTNVCEPLKGYTRNKGG
TEYQMYSPFTLFADACTPDAKDSLAFDEAVSQYLANKSADNKAKVAAFFNKWIAVNKGLVELSANAPLVQPILPLSKKLS
DASQELLLVLDNKSTLKTADLKTLIEQCNTKDHADVELSVYESLKKLI

Sequences:

>Translated_688_residues
MKYLFVLLLAGVTANAQMQKEQLNLMPWPQNVVVNDGNFTLTKNFKVNISGNPDSRIFGGVTRFLRRLDGRTGIFFEQGF
ITKLNEFPNAELQINCTKNGKIGLYEDESYSLDVKANKITINATSDLGALHGLETLLQLLQNDSKKFYFPVSQISDFPRF
TWRGLMLDASRHFQPVDVVKRNLDALAAMKMNVFHWHLVDDQGWRIETKKHPKLIELASDGLYYTQEEIRNIVKYADERG
ILIVPEIDVPGHGSAILTAYPEIGSKVITLTGGTSEKNIQGTAISTYRIERNAGIFSPTLDPSNPKTYKILSELFDEVCP
LFPGAYFHIGGDENEGKDWDANPKIQEFKKKHNLKTNHELQTYFTMQLAPMLKKHGKQLMGWEEILTKDLSKEAIVHSWR
GPNEGMVAGQSLVDAVKKGYKTVLSNGFYIDLMYPVASHYLNDPMPKGADLSAEEKARILGGEATMWTELATPETFDSRV
WPRTAAIAERLWSAENITDVANMRKRLESVSFRLEELGLTHIKNKAVILRNIANNQNIKSVNEFTNVCEPLKGYTRNKGG
TEYQMYSPFTLFADACTPDAKDSLAFDEAVSQYLANKSADNKAKVAAFFNKWIAVNKGLVELSANAPLVQPILPLSKKLS
DASQELLLVLDNKSTLKTADLKTLIEQCNTKDHADVELSVYESLKKLI
>Mature_688_residues
MKYLFVLLLAGVTANAQMQKEQLNLMPWPQNVVVNDGNFTLTKNFKVNISGNPDSRIFGGVTRFLRRLDGRTGIFFEQGF
ITKLNEFPNAELQINCTKNGKIGLYEDESYSLDVKANKITINATSDLGALHGLETLLQLLQNDSKKFYFPVSQISDFPRF
TWRGLMLDASRHFQPVDVVKRNLDALAAMKMNVFHWHLVDDQGWRIETKKHPKLIELASDGLYYTQEEIRNIVKYADERG
ILIVPEIDVPGHGSAILTAYPEIGSKVITLTGGTSEKNIQGTAISTYRIERNAGIFSPTLDPSNPKTYKILSELFDEVCP
LFPGAYFHIGGDENEGKDWDANPKIQEFKKKHNLKTNHELQTYFTMQLAPMLKKHGKQLMGWEEILTKDLSKEAIVHSWR
GPNEGMVAGQSLVDAVKKGYKTVLSNGFYIDLMYPVASHYLNDPMPKGADLSAEEKARILGGEATMWTELATPETFDSRV
WPRTAAIAERLWSAENITDVANMRKRLESVSFRLEELGLTHIKNKAVILRNIANNQNIKSVNEFTNVCEPLKGYTRNKGG
TEYQMYSPFTLFADACTPDAKDSLAFDEAVSQYLANKSADNKAKVAAFFNKWIAVNKGLVELSANAPLVQPILPLSKKLS
DASQELLLVLDNKSTLKTADLKTLIEQCNTKDHADVELSVYESLKKLI

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=440, Percent_Identity=32.5, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI189181666, Length=516, Percent_Identity=30.6201550387597, Blast_Score=230, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17569815, Length=442, Percent_Identity=29.6380090497738, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24653074, Length=499, Percent_Identity=29.6593186372746, Blast_Score=176, Evalue=5e-44,
Organism=Drosophila melanogaster, GI45551090, Length=497, Percent_Identity=29.3762575452716, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI281365639, Length=432, Percent_Identity=28.9351851851852, Blast_Score=168, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24657474, Length=432, Percent_Identity=28.9351851851852, Blast_Score=168, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24657468, Length=432, Percent_Identity=28.9351851851852, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI17647501, Length=432, Percent_Identity=28.9351851851852, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI17933586, Length=427, Percent_Identity=28.8056206088993, Blast_Score=161, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 77288; Mature: 77288

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLFVLLLAGVTANAQMQKEQLNLMPWPQNVVVNDGNFTLTKNFKVNISGNPDSRIFGG
CHHHHEEHHHCCCCCCHHHHHHCCCCCCCCCEEEECCCEEEEEEEEEEECCCCCCHHHHH
VTRFLRRLDGRTGIFFEQGFITKLNEFPNAELQINCTKNGKIGLYEDESYSLDVKANKIT
HHHHHHHHCCCCCEEEECCHHHHHHCCCCCEEEEEECCCCCEEEEECCCEEEEEEEEEEE
INATSDLGALHGLETLLQLLQNDSKKFYFPVSQISDFPRFTWRGLMLDASRHFQPVDVVK
EEECCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCHHEEEEEEECCCCCCHHHHHH
RNLDALAAMKMNVFHWHLVDDQGWRIETKKHPKLIELASDGLYYTQEEIRNIVKYADERG
HHHHHHHHHEEEEEEEEEECCCCCEEECCCCCCEEEEECCCCEECHHHHHHHHHHCCCCC
ILIVPEIDVPGHGSAILTAYPEIGSKVITLTGGTSEKNIQGTAISTYRIERNAGIFSPTL
EEEEECCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCC
DPSNPKTYKILSELFDEVCPLFPGAYFHIGGDENEGKDWDANPKIQEFKKKHNLKTNHEL
CCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
QTYFTMQLAPMLKKHGKQLMGWEEILTKDLSKEAIVHSWRGPNEGMVAGQSLVDAVKKGY
CEEHHHHHHHHHHHCCHHHCCHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
KTVLSNGFYIDLMYPVASHYLNDPMPKGADLSAEEKARILGGEATMWTELATPETFDSRV
HHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCC
WPRTAAIAERLWSAENITDVANMRKRLESVSFRLEELGLTHIKNKAVILRNIANNQNIKS
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHH
VNEFTNVCEPLKGYTRNKGGTEYQMYSPFTLFADACTPDAKDSLAFDEAVSQYLANKSAD
HHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCC
NKAKVAAFFNKWIAVNKGLVELSANAPLVQPILPLSKKLSDASQELLLVLDNKSTLKTAD
CHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
LKTLIEQCNTKDHADVELSVYESLKKLI
HHHHHHHCCCCCCCCEEHHHHHHHHHHC
>Mature Secondary Structure
MKYLFVLLLAGVTANAQMQKEQLNLMPWPQNVVVNDGNFTLTKNFKVNISGNPDSRIFGG
CHHHHEEHHHCCCCCCHHHHHHCCCCCCCCCEEEECCCEEEEEEEEEEECCCCCCHHHHH
VTRFLRRLDGRTGIFFEQGFITKLNEFPNAELQINCTKNGKIGLYEDESYSLDVKANKIT
HHHHHHHHCCCCCEEEECCHHHHHHCCCCCEEEEEECCCCCEEEEECCCEEEEEEEEEEE
INATSDLGALHGLETLLQLLQNDSKKFYFPVSQISDFPRFTWRGLMLDASRHFQPVDVVK
EEECCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCHHEEEEEEECCCCCCHHHHHH
RNLDALAAMKMNVFHWHLVDDQGWRIETKKHPKLIELASDGLYYTQEEIRNIVKYADERG
HHHHHHHHHEEEEEEEEEECCCCCEEECCCCCCEEEEECCCCEECHHHHHHHHHHCCCCC
ILIVPEIDVPGHGSAILTAYPEIGSKVITLTGGTSEKNIQGTAISTYRIERNAGIFSPTL
EEEEECCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCC
DPSNPKTYKILSELFDEVCPLFPGAYFHIGGDENEGKDWDANPKIQEFKKKHNLKTNHEL
CCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
QTYFTMQLAPMLKKHGKQLMGWEEILTKDLSKEAIVHSWRGPNEGMVAGQSLVDAVKKGY
CEEHHHHHHHHHHHCCHHHCCHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
KTVLSNGFYIDLMYPVASHYLNDPMPKGADLSAEEKARILGGEATMWTELATPETFDSRV
HHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCC
WPRTAAIAERLWSAENITDVANMRKRLESVSFRLEELGLTHIKNKAVILRNIANNQNIKS
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHH
VNEFTNVCEPLKGYTRNKGGTEYQMYSPFTLFADACTPDAKDSLAFDEAVSQYLANKSAD
HHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCC
NKAKVAAFFNKWIAVNKGLVELSANAPLVQPILPLSKKLSDASQELLLVLDNKSTLKTAD
CHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
LKTLIEQCNTKDHADVELSVYESLKKLI
HHHHHHHCCCCCCCCEEHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]