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The map label for this gene is rprY [H]

Identifier: 146302248

GI number: 146302248

Start: 5463557

End: 5464249

Strand: Direct

Name: rprY [H]

Synonym: Fjoh_4521

Alternate gene names: 146302248

Gene position: 5463557-5464249 (Clockwise)

Preceding gene: 146302247

Following gene: 146302249

Centisome position: 89.61

GC content: 30.59

Gene sequence:

>693_bases
TTGAAAAGATTACTTTTAGCCGAAGACGATTTTGATTTTGCAGCAATCTTAAAACAATATTTAGAACTGCATCAATTTGA
AGTTATATGGGCAGAAAATGGCGAAATTGCTTTAGATTATTTTAAAAATCAAACTTTTGATATTTGTGTTTTCGATGTAA
TGATGCCCAAACTGGACGGGTTTTCACTGGCCGAAAAAACAATTACAATCAATCCCGAAATTCCTTTTATTTTTTTGACA
GCCAGAAAGTTAAAAGAAGATAAAATCATTGGCTTAAAACTAGGCGCAGACGATTATATTGTAAAACCTTTTGAAGTTGA
CGAACTGGTGCTGCGCCTGCAGAATATCTTAAAGAGAATCGAACAAAAGAGAAGTCTGGAGGGAAATAATGTAATTGAAA
TAGGATCATATATTTTTGATAACGAACGTTTAACCCTTAATATTAAAAATCACGTTCAACAGCTTACAGAGAAAGAAGCT
TCACTCATTGAGTATTTATATTTAAATCATAATCAGTTATTAAAAAGAGATCAGATTTTAATGTCGGTTTGGAAAAAAGA
CGATTATTTTTCCGGACGAAGCATGGATGTTTTTATCAGCAGACTTAGAAAATATTTTAATTCAGATCCAAAAATCAAAA
TTGAAAGCGTTCGAAATGTTGGATTAGAATTTAAAATAGAAAAAACACAATAA

Upstream 100 bases:

>100_bases
GCGCAAATTGTAAAAGCGCATCAGGGCTCTGTTAACGTTATCAGCGACCTGGGAAAAGGAGCCCGATTTACTATTTTATT
AAAAGTTTAATTACCTTATT

Downstream 100 bases:

>100_bases
GGATCGTGAAAATGATATAAGTTTTAAAATCAATTGTATAATACATTCAGAATAAAACAATTATACATTTGAATAACTTT
AAAATTCAAAATCATGAACC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKRLLLAEDDFDFAAILKQYLELHQFEVIWAENGEIALDYFKNQTFDICVFDVMMPKLDGFSLAEKTITINPEIPFIFLT
ARKLKEDKIIGLKLGADDYIVKPFEVDELVLRLQNILKRIEQKRSLEGNNVIEIGSYIFDNERLTLNIKNHVQQLTEKEA
SLIEYLYLNHNQLLKRDQILMSVWKKDDYFSGRSMDVFISRLRKYFNSDPKIKIESVRNVGLEFKIEKTQ

Sequences:

>Translated_230_residues
MKRLLLAEDDFDFAAILKQYLELHQFEVIWAENGEIALDYFKNQTFDICVFDVMMPKLDGFSLAEKTITINPEIPFIFLT
ARKLKEDKIIGLKLGADDYIVKPFEVDELVLRLQNILKRIEQKRSLEGNNVIEIGSYIFDNERLTLNIKNHVQQLTEKEA
SLIEYLYLNHNQLLKRDQILMSVWKKDDYFSGRSMDVFISRLRKYFNSDPKIKIESVRNVGLEFKIEKTQ
>Mature_230_residues
MKRLLLAEDDFDFAAILKQYLELHQFEVIWAENGEIALDYFKNQTFDICVFDVMMPKLDGFSLAEKTITINPEIPFIFLT
ARKLKEDKIIGLKLGADDYIVKPFEVDELVLRLQNILKRIEQKRSLEGNNVIEIGSYIFDNERLTLNIKNHVQQLTEKEA
SLIEYLYLNHNQLLKRDQILMSVWKKDDYFSGRSMDVFISRLRKYFNSDPKIKIESVRNVGLEFKIEKTQ

Specific function: Member of the two-component regulatory system rprX/rprY [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=31.7391304347826, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=29.7297297297297, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=28.6343612334802, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=30, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI2367329, Length=208, Percent_Identity=33.1730769230769, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1788394, Length=209, Percent_Identity=28.7081339712919, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1786784, Length=235, Percent_Identity=28.936170212766, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=27.3972602739726, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787229, Length=210, Percent_Identity=28.0952380952381, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=27.5423728813559, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=27.8026905829596, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=26.027397260274, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=27.5423728813559, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=24.8888888888889, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=32.2033898305085, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27150; Mature: 27150

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLLAEDDFDFAAILKQYLELHQFEVIWAENGEIALDYFKNQTFDICVFDVMMPKLDG
CCCEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCEEEEEEEEHHCCCCC
FSLAEKTITINPEIPFIFLTARKLKEDKIIGLKLGADDYIVKPFEVDELVLRLQNILKRI
CCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHHH
EQKRSLEGNNVIEIGSYIFDNERLTLNIKNHVQQLTEKEASLIEYLYLNHNQLLKRDQIL
HHHHCCCCCCEEEECCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
MSVWKKDDYFSGRSMDVFISRLRKYFNSDPKIKIESVRNVGLEFKIEKTQ
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHCCCEEEEEECCC
>Mature Secondary Structure
MKRLLLAEDDFDFAAILKQYLELHQFEVIWAENGEIALDYFKNQTFDICVFDVMMPKLDG
CCCEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCEEEEEEEEHHCCCCC
FSLAEKTITINPEIPFIFLTARKLKEDKIIGLKLGADDYIVKPFEVDELVLRLQNILKRI
CCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHHH
EQKRSLEGNNVIEIGSYIFDNERLTLNIKNHVQQLTEKEASLIEYLYLNHNQLLKRDQIL
HHHHCCCCCCEEEECCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
MSVWKKDDYFSGRSMDVFISRLRKYFNSDPKIKIESVRNVGLEFKIEKTQ
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]