Click here to switch to the map view.

The map label for this gene is rprX [H]

Identifier: 146302247

GI number: 146302247

Start: 5462188

End: 5463546

Strand: Direct

Name: rprX [H]

Synonym: Fjoh_4520

Alternate gene names: 146302247

Gene position: 5462188-5463546 (Clockwise)

Preceding gene: 146302246

Following gene: 146302248

Centisome position: 89.59

GC content: 32.6

Gene sequence:

>1359_bases
ATGAAACAAAGAATCAATTTATTAATAGCATTTTCAGTTGCGGCGCTGGTCGTTCTGTCTGCTGTGCAATGCTATTTGGT
AAAAACCACTTACGATTATAAAGTGGCGCAGTTTCATACTCAGATCAAAAATGAAATTGCTCAGATTTCAAATAATTACA
GCGATATTGATTCGGTTTTGGTTTCGAGAAAAGAAACACTTTATACCAATTTATCAGAGAAATATTTTCAGGGAAAAAAA
TCTAAAACTGACATTAAAAACGGAATTTTAGAAAATGAATACCGAAGTGCATTAACAGCAGAAATTCAACGAAAATTTGA
AAGAGACCTGCCTAATTTTAAAATTGATTTTGCAATTGTGCTTAACAAATTCATTTTGTACCAAAACACAAAAAAGGCCG
ATACTATTTTTTCTGAAAAGCCTTTTATCCAAAACAAATTATACGGAAATCTGGCTTCGTTAAATCATGCCTTTTTGGTT
CGGAATTATGTAGGCACGACAAACGGAACTTTTAAAAATCAGGATTATAAATTATTGACAGAAGATTCGATGTACGTTTC
GGTAATCGATTGGGAAATGATCATTTTAAGACGAATGGCCTTTGTTCTTGTTTTGTCTTTACTGTCGATTCTTACGCTTA
TAACTTTGTTTGTAATTGCGCTGAAAGCATTAATTAAGCAGAAAAAAGTGAGCGATGTAAAAACCGATTTCATCAATAAT
ATTACACATGAGCTCAAAACGCCTTTGGCAACTTTAGGAATTTCTACTAAAATTCTGGAGCAGAAAAACATTCGCGACAA
TGACGAAAGTTTTAATAGTATTGTCAATACCATTTCACGTCAAAACAACCGCCTTCAAAGCCTGATCGATCAGGTTATGG
CAAATTCATTGGCAGAAAATGAAATTGAACTGCAAAAAGAGAAAATCGAAACCGAAGTTTTTCTGCAGACTATTGTAAAT
GATTTTAAAATCGGTTATCCCAAAATACATATTCAGACGCATTTTGAAACTCAAAAAACAAATCTCGTTTTAGATAAATT
TCATTTAACAACGGCTCTTTTAAATGTTTTGGAAAATGCTGTAAAATATGGTTCAAATACTATTACAATAAAAACGAAAC
AAATTGAGGATCAGTTTTCTATTAGTATTGAAGATGACGGCATTGGAATTTCTAAAAATAAACAAGCGCTTCTTTTTGAA
AAATTTTATCGCGTAGAACAAGGCAACCTTCATAATACAAAAGGTTTAGGTTTGGGACTGTATTATGTGGCGCAAATTGT
AAAAGCGCATCAGGGCTCTGTTAACGTTATCAGCGACCTGGGAAAAGGAGCCCGATTTACTATTTTATTAAAAGTTTAA

Upstream 100 bases:

>100_bases
GTATGGAAATTTTTCAAGAGAATAAAAATAGATTTGAACCTACATAAAACAAAATACATTATATGTAAACCCGTTCAATC
TGTAAAAATCAGTGGGCTAT

Downstream 100 bases:

>100_bases
TTACCTTATTTTGAAAAGATTACTTTTAGCCGAAGACGATTTTGATTTTGCAGCAATCTTAAAACAATATTTAGAACTGC
ATCAATTTGAAGTTATATGG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKQRINLLIAFSVAALVVLSAVQCYLVKTTYDYKVAQFHTQIKNEIAQISNNYSDIDSVLVSRKETLYTNLSEKYFQGKK
SKTDIKNGILENEYRSALTAEIQRKFERDLPNFKIDFAIVLNKFILYQNTKKADTIFSEKPFIQNKLYGNLASLNHAFLV
RNYVGTTNGTFKNQDYKLLTEDSMYVSVIDWEMIILRRMAFVLVLSLLSILTLITLFVIALKALIKQKKVSDVKTDFINN
ITHELKTPLATLGISTKILEQKNIRDNDESFNSIVNTISRQNNRLQSLIDQVMANSLAENEIELQKEKIETEVFLQTIVN
DFKIGYPKIHIQTHFETQKTNLVLDKFHLTTALLNVLENAVKYGSNTITIKTKQIEDQFSISIEDDGIGISKNKQALLFE
KFYRVEQGNLHNTKGLGLGLYYVAQIVKAHQGSVNVISDLGKGARFTILLKV

Sequences:

>Translated_452_residues
MKQRINLLIAFSVAALVVLSAVQCYLVKTTYDYKVAQFHTQIKNEIAQISNNYSDIDSVLVSRKETLYTNLSEKYFQGKK
SKTDIKNGILENEYRSALTAEIQRKFERDLPNFKIDFAIVLNKFILYQNTKKADTIFSEKPFIQNKLYGNLASLNHAFLV
RNYVGTTNGTFKNQDYKLLTEDSMYVSVIDWEMIILRRMAFVLVLSLLSILTLITLFVIALKALIKQKKVSDVKTDFINN
ITHELKTPLATLGISTKILEQKNIRDNDESFNSIVNTISRQNNRLQSLIDQVMANSLAENEIELQKEKIETEVFLQTIVN
DFKIGYPKIHIQTHFETQKTNLVLDKFHLTTALLNVLENAVKYGSNTITIKTKQIEDQFSISIEDDGIGISKNKQALLFE
KFYRVEQGNLHNTKGLGLGLYYVAQIVKAHQGSVNVISDLGKGARFTILLKV
>Mature_452_residues
MKQRINLLIAFSVAALVVLSAVQCYLVKTTYDYKVAQFHTQIKNEIAQISNNYSDIDSVLVSRKETLYTNLSEKYFQGKK
SKTDIKNGILENEYRSALTAEIQRKFERDLPNFKIDFAIVLNKFILYQNTKKADTIFSEKPFIQNKLYGNLASLNHAFLV
RNYVGTTNGTFKNQDYKLLTEDSMYVSVIDWEMIILRRMAFVLVLSLLSILTLITLFVIALKALIKQKKVSDVKTDFINN
ITHELKTPLATLGISTKILEQKNIRDNDESFNSIVNTISRQNNRLQSLIDQVMANSLAENEIELQKEKIETEVFLQTIVN
DFKIGYPKIHIQTHFETQKTNLVLDKFHLTTALLNVLENAVKYGSNTITIKTKQIEDQFSISIEDDGIGISKNKQALLFE
KFYRVEQGNLHNTKGLGLGLYYVAQIVKAHQGSVNVISDLGKGARFTILLKV

Specific function: Member of the two-component regulatory system rprX/rprY. May activate rprY by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=25.1046025104602, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790346, Length=218, Percent_Identity=24.7706422018349, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=28.82096069869, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=220, Percent_Identity=23.6363636363636, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=26.0504201680672, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=25.2136752136752, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=202, Percent_Identity=24.7524752475248, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788393, Length=212, Percent_Identity=26.8867924528302, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=28.5067873303167, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=25.6521739130435, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789808, Length=205, Percent_Identity=23.9024390243902, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787374, Length=215, Percent_Identity=23.2558139534884, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788713, Length=237, Percent_Identity=24.4725738396624, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1789149, Length=245, Percent_Identity=24.0816326530612, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51605; Mature: 51605

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRINLLIAFSVAALVVLSAVQCYLVKTTYDYKVAQFHTQIKNEIAQISNNYSDIDSVL
CCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VSRKETLYTNLSEKYFQGKKSKTDIKNGILENEYRSALTAEIQRKFERDLPNFKIDFAIV
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
LNKFILYQNTKKADTIFSEKPFIQNKLYGNLASLNHAFLVRNYVGTTNGTFKNQDYKLLT
HHHHHHHCCCCHHHHHHCCCCCHHHHHHCCHHHCCHHHHHHHHCCCCCCCCCCCCCEEEE
EDSMYVSVIDWEMIILRRMAFVLVLSLLSILTLITLFVIALKALIKQKKVSDVKTDFINN
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITHELKTPLATLGISTKILEQKNIRDNDESFNSIVNTISRQNNRLQSLIDQVMANSLAEN
HHHHHHCCHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EIELQKEKIETEVFLQTIVNDFKIGYPKIHIQTHFETQKTNLVLDKFHLTTALLNVLENA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHH
VKYGSNTITIKTKQIEDQFSISIEDDGIGISKNKQALLFEKFYRVEQGNLHNTKGLGLGL
HHHCCCEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHH
YYVAQIVKAHQGSVNVISDLGKGARFTILLKV
HHHHHHHHHCCCCHHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure
MKQRINLLIAFSVAALVVLSAVQCYLVKTTYDYKVAQFHTQIKNEIAQISNNYSDIDSVL
CCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VSRKETLYTNLSEKYFQGKKSKTDIKNGILENEYRSALTAEIQRKFERDLPNFKIDFAIV
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
LNKFILYQNTKKADTIFSEKPFIQNKLYGNLASLNHAFLVRNYVGTTNGTFKNQDYKLLT
HHHHHHHCCCCHHHHHHCCCCCHHHHHHCCHHHCCHHHHHHHHCCCCCCCCCCCCCEEEE
EDSMYVSVIDWEMIILRRMAFVLVLSLLSILTLITLFVIALKALIKQKKVSDVKTDFINN
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITHELKTPLATLGISTKILEQKNIRDNDESFNSIVNTISRQNNRLQSLIDQVMANSLAEN
HHHHHHCCHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EIELQKEKIETEVFLQTIVNDFKIGYPKIHIQTHFETQKTNLVLDKFHLTTALLNVLENA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHH
VKYGSNTITIKTKQIEDQFSISIEDDGIGISKNKQALLFEKFYRVEQGNLHNTKGLGLGL
HHHCCCEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHH
YYVAQIVKAHQGSVNVISDLGKGARFTILLKV
HHHHHHHHHCCCCHHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]