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The map label for this gene is lytT [H]

Identifier: 146302222

GI number: 146302222

Start: 5424296

End: 5424991

Strand: Direct

Name: lytT [H]

Synonym: Fjoh_4495

Alternate gene names: 146302222

Gene position: 5424296-5424991 (Clockwise)

Preceding gene: 146302221

Following gene: 146302223

Centisome position: 88.97

GC content: 32.9

Gene sequence:

>696_bases
ATGAAAATTCTAATTATTGAAGACGAAGCGAGAATTGCAAAACGAATCGAAAGAATGACCAGAGGTTTTTTTAATAAAGA
TGTCCAGATTTTTCTTTCTGATTCGGTTGAAAACGGTTTAAATACAATTAATCAAAATGAAATTGATTTATTGCTTCTGG
ATTTAAACCTAAATGGTGAAGATGGATTTGATGTCCTGCAGACTGTTGTATCAAAATCTTTTCAAACCATTATTATTTCA
GCATATACAGACAAAGCTATTACTGCATTTAATTACGGCGTTTTAGATTTTGTACCCAAACCATTTGACGAAAACAGACT
CGCACAAGCTTTTACCCGTTATACAACACCAGAAAGAAAAGCCAGCAGTGAAATTCAGTTTTTAGCTGTAAAAAAAGCAA
AAACTATTAAACTCATTACTATTACAGATATTAAATACATAAAAGGCGCAGGCATTTATACAGAATTGCATTTACATGAC
GGCCGTATAGAATTACATGACAAATCGCTTGAATCACTGGAAAAACTGCTGCCAATAACTTTTGAACGAATACACAAATC
ATACATTCTCTGCTGGAATGAAGCAGAAAAGCTCGTTGTAGAAGCCGGAGGCCGATATCAGATGTTACTAAAAAATGGAG
AAATACTACCTGTAGGCCGTTCTAAATATAAAGAAATCAAATATAAATTGATATAG

Upstream 100 bases:

>100_bases
TAAAGGCCCGATTAAATGAAAGTTATGGCAATAACTGGCAGTTTGATTCTTTTGCTGTTGAAGAAGGATGGCTCACAGAA
ATTAAAATTTTTGATACAAA

Downstream 100 bases:

>100_bases
AAAGTCATCTTCTAAAATGAGAATTAAGCAATTCATTTTAATAATTATATAAATCAGCAGAAATAAAAAGTTTTACTTTT
AAATAATTCTAATTGAGAAA

Product: LytTR family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKILIIEDEARIAKRIERMTRGFFNKDVQIFLSDSVENGLNTINQNEIDLLLLDLNLNGEDGFDVLQTVVSKSFQTIIIS
AYTDKAITAFNYGVLDFVPKPFDENRLAQAFTRYTTPERKASSEIQFLAVKKAKTIKLITITDIKYIKGAGIYTELHLHD
GRIELHDKSLESLEKLLPITFERIHKSYILCWNEAEKLVVEAGGRYQMLLKNGEILPVGRSKYKEIKYKLI

Sequences:

>Translated_231_residues
MKILIIEDEARIAKRIERMTRGFFNKDVQIFLSDSVENGLNTINQNEIDLLLLDLNLNGEDGFDVLQTVVSKSFQTIIIS
AYTDKAITAFNYGVLDFVPKPFDENRLAQAFTRYTTPERKASSEIQFLAVKKAKTIKLITITDIKYIKGAGIYTELHLHD
GRIELHDKSLESLEKLLPITFERIHKSYILCWNEAEKLVVEAGGRYQMLLKNGEILPVGRSKYKEIKYKLI
>Mature_231_residues
MKILIIEDEARIAKRIERMTRGFFNKDVQIFLSDSVENGLNTINQNEIDLLLLDLNLNGEDGFDVLQTVVSKSFQTIIIS
AYTDKAITAFNYGVLDFVPKPFDENRLAQAFTRYTTPERKASSEIQFLAVKKAKTIKLITITDIKYIKGAGIYTELHLHD
GRIELHDKSLESLEKLLPITFERIHKSYILCWNEAEKLVVEAGGRYQMLLKNGEILPVGRSKYKEIKYKLI

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=244, Percent_Identity=24.1803278688525, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788724, Length=243, Percent_Identity=23.8683127572016, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26532; Mature: 26532

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIIEDEARIAKRIERMTRGFFNKDVQIFLSDSVENGLNTINQNEIDLLLLDLNLNGE
CEEEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHCCCCCCEEEEEEEEECCCC
DGFDVLQTVVSKSFQTIIISAYTDKAITAFNYGVLDFVPKPFDENRLAQAFTRYTTPERK
CCHHHHHHHHHCCEEEEEEEEECCCEEEEECCCHHHCCCCCCCCHHHHHHHHHCCCCCCC
ASSEIQFLAVKKAKTIKLITITDIKYIKGAGIYTELHLHDGRIELHDKSLESLEKLLPIT
CCCCEEEEEEECCCEEEEEEEECEEEECCCCEEEEEEEECCEEEECHHHHHHHHHHHHHH
FERIHKSYILCWNEAEKLVVEAGGRYQMLLKNGEILPVGRSKYKEIKYKLI
HHHHHHHEEEEECCCCEEEEECCCCEEEEEECCCEEECCCHHHHHEEEECC
>Mature Secondary Structure
MKILIIEDEARIAKRIERMTRGFFNKDVQIFLSDSVENGLNTINQNEIDLLLLDLNLNGE
CEEEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHCCCCCCEEEEEEEEECCCC
DGFDVLQTVVSKSFQTIIISAYTDKAITAFNYGVLDFVPKPFDENRLAQAFTRYTTPERK
CCHHHHHHHHHCCEEEEEEEEECCCEEEEECCCHHHCCCCCCCCHHHHHHHHHCCCCCCC
ASSEIQFLAVKKAKTIKLITITDIKYIKGAGIYTELHLHDGRIELHDKSLESLEKLLPIT
CCCCEEEEEEECCCEEEEEEEECEEEECCCCEEEEEEEECCEEEECHHHHHHHHHHHHHH
FERIHKSYILCWNEAEKLVVEAGGRYQMLLKNGEILPVGRSKYKEIKYKLI
HHHHHHHEEEEECCCCEEEEECCCCEEEEEECCCEEECCCHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]