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The map label for this gene is apbE [H]

Identifier: 146302196

GI number: 146302196

Start: 5387173

End: 5388102

Strand: Direct

Name: apbE [H]

Synonym: Fjoh_4467

Alternate gene names: 146302196

Gene position: 5387173-5388102 (Clockwise)

Preceding gene: 146302195

Following gene: 146302197

Centisome position: 88.36

GC content: 41.29

Gene sequence:

>930_bases
ATGACAGCAAAGGAATTTCGCAAAACCGAAAAGCTGATGGGCAATGCCTTTGAAATCACGGTAGTGGGAGCAGATGAGGT
TTTAGCCTATCAACAAATTGATTCCGCCATTGGGGAGATTAAACGGATTGAGCAATTGTTTACCACTTTTAAAACGGACA
GTCAGACCAACCTGATTAATAACAATGCCGGAATACAGGCGGTAAAAGTAGATGAAGAAGTTTTTAACCTGATAGAAAGA
AGCCTCCGCATCAGCCGTATTACCAATGGTTTTTTTGACATCACTTACGGAGGTGTGGATAAAAGTCTGTGGAATTTTGA
TAGGTCAATGACCAGACTGCCCGATGCCGAAACGGCAAAAAAACTGGTTTATCTCATTAATTATCAAAATGTAATCCTGA
ACAGGGAGAACAGTACCGTCTATCTCAAAGAAAAAGGGATGCGTATTGGTTTCGGTGGAATAGGAAAAGGCTATGCCGCA
GAAATGGCCAAGAATGTTTTGCAAAAACAAGGTGTAGGTTCAGGTATCATCAATGCTTCAGGAGACTTAACAGTATGGGG
TACACAGGCCGATGGTAAACCCTGGACAATAGGCATTGCCAACCCGGACCAAGCCCGGCTGCCATTTTCTTATTTGAACC
TTACGGACACTGCCATTGCCACCTCGGGAAACTATGAAAAATATGTGAAGGTTGGCGGTAAAAAATACTCGCACACCATC
AATCCGAAAACAGGAATGCCAATTACCGGGATAAAAAGTGTAACAGTTATTTGCCCCAATGCAGAAATCGCAGATGCTAT
GGCTACCCCTATCAGTATCATGGGTGTTAAGGCAGGATTGGAAATGATAAACCAAATCCATCAGATAGAATGCATCATCA
TAGATGACAAAAACAAAATATTCACTTCAAAAAATATCAATTTAATATGA

Upstream 100 bases:

>100_bases
ATGCGGATGGAAAAATAATAAAAACCTGGGAAGGCCTCCCGAAAGAAGGTGTTGATGGGTTTACAAACGAAATCATAACC
CTATACAAAAAAGTAAAAAA

Downstream 100 bases:

>100_bases
AAACAAATAAAATAATCCTGCTAAGTGCTATCGGTACATTATCGCTTGGTTCCTGCACCACAGTGAAAGAATATCAGAAA
AACAAACTCAACGATGCCGA

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTAKEFRKTEKLMGNAFEITVVGADEVLAYQQIDSAIGEIKRIEQLFTTFKTDSQTNLINNNAGIQAVKVDEEVFNLIER
SLRISRITNGFFDITYGGVDKSLWNFDRSMTRLPDAETAKKLVYLINYQNVILNRENSTVYLKEKGMRIGFGGIGKGYAA
EMAKNVLQKQGVGSGIINASGDLTVWGTQADGKPWTIGIANPDQARLPFSYLNLTDTAIATSGNYEKYVKVGGKKYSHTI
NPKTGMPITGIKSVTVICPNAEIADAMATPISIMGVKAGLEMINQIHQIECIIIDDKNKIFTSKNINLI

Sequences:

>Translated_309_residues
MTAKEFRKTEKLMGNAFEITVVGADEVLAYQQIDSAIGEIKRIEQLFTTFKTDSQTNLINNNAGIQAVKVDEEVFNLIER
SLRISRITNGFFDITYGGVDKSLWNFDRSMTRLPDAETAKKLVYLINYQNVILNRENSTVYLKEKGMRIGFGGIGKGYAA
EMAKNVLQKQGVGSGIINASGDLTVWGTQADGKPWTIGIANPDQARLPFSYLNLTDTAIATSGNYEKYVKVGGKKYSHTI
NPKTGMPITGIKSVTVICPNAEIADAMATPISIMGVKAGLEMINQIHQIECIIIDDKNKIFTSKNINLI
>Mature_308_residues
TAKEFRKTEKLMGNAFEITVVGADEVLAYQQIDSAIGEIKRIEQLFTTFKTDSQTNLINNNAGIQAVKVDEEVFNLIERS
LRISRITNGFFDITYGGVDKSLWNFDRSMTRLPDAETAKKLVYLINYQNVILNRENSTVYLKEKGMRIGFGGIGKGYAAE
MAKNVLQKQGVGSGIINASGDLTVWGTQADGKPWTIGIANPDQARLPFSYLNLTDTAIATSGNYEKYVKVGGKKYSHTIN
PKTGMPITGIKSVTVICPNAEIADAMATPISIMGVKAGLEMINQIHQIECIIIDDKNKIFTSKNINLI

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=281, Percent_Identity=27.0462633451957, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 34032; Mature: 33900

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKEFRKTEKLMGNAFEITVVGADEVLAYQQIDSAIGEIKRIEQLFTTFKTDSQTNLIN
CCHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
NNAGIQAVKVDEEVFNLIERSLRISRITNGFFDITYGGVDKSLWNFDRSMTRLPDAETAK
CCCCEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHH
KLVYLINYQNVILNRENSTVYLKEKGMRIGFGGIGKGYAAEMAKNVLQKQGVGSGIINAS
HEEEEEEECEEEEECCCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHCCCCCCEEECC
GDLTVWGTQADGKPWTIGIANPDQARLPFSYLNLTDTAIATSGNYEKYVKVGGKKYSHTI
CCEEEEEECCCCCEEEEEECCCCCCCCCCHHCCCCHHEEECCCCCCEEEEECCCEEEEEC
NPKTGMPITGIKSVTVICPNAEIADAMATPISIMGVKAGLEMINQIHQIECIIIDDKNKI
CCCCCCCCCCCCEEEEEECCCHHHHHHHCCHHEEHHHHHHHHHHHHHEEEEEEEECCCEE
FTSKNINLI
EECCCCCCC
>Mature Secondary Structure 
TAKEFRKTEKLMGNAFEITVVGADEVLAYQQIDSAIGEIKRIEQLFTTFKTDSQTNLIN
CHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
NNAGIQAVKVDEEVFNLIERSLRISRITNGFFDITYGGVDKSLWNFDRSMTRLPDAETAK
CCCCEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHH
KLVYLINYQNVILNRENSTVYLKEKGMRIGFGGIGKGYAAEMAKNVLQKQGVGSGIINAS
HEEEEEEECEEEEECCCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHCCCCCCEEECC
GDLTVWGTQADGKPWTIGIANPDQARLPFSYLNLTDTAIATSGNYEKYVKVGGKKYSHTI
CCEEEEEECCCCCEEEEEECCCCCCCCCCHHCCCCHHEEECCCCCCEEEEECCCEEEEEC
NPKTGMPITGIKSVTVICPNAEIADAMATPISIMGVKAGLEMINQIHQIECIIIDDKNKI
CCCCCCCCCCCCEEEEEECCCHHHHHHHCCHHEEHHHHHHHHHHHHHEEEEEEEECCCEE
FTSKNINLI
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]