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The map label for this gene is yraR [H]

Identifier: 146302172

GI number: 146302172

Start: 5361908

End: 5362612

Strand: Direct

Name: yraR [H]

Synonym: Fjoh_4440

Alternate gene names: 146302172

Gene position: 5361908-5362612 (Clockwise)

Preceding gene: 146302171

Following gene: 146302173

Centisome position: 87.95

GC content: 30.64

Gene sequence:

>705_bases
ATGTCAATTTTAGAAAACAATAAAATGAAAAAAGCGGTATTATTTGGAGCCAGTGGCTTTGTTGGTTCTGAATTGCTTTT
AAAATTATTAAACAACCCGATTTACGAAGAAGTAACTATTGTTGTAAGGAAACCATTAAATAGTACTCATTCTAAGTTGA
GAATTTTAATAGGTGACTTTAATTCAATGCCTGGTTTAATTGAAAAAATTAGTGCTGATACTGTTTTTATTGCCCTTGGT
GCCATTCAGAACAGCAGACAAAACTCAGATGAATTTTATCAAATTGATCATGATTATCCTGTAATAGCAGCAAAAATATT
AAAAGAAAATGGAGCAAAATCTGTTTTTCTGGTAACAGCAGCCGGAGCAAATCCAAATTCAAAATTCAGGTACATAAAAA
CAAAAGGAGAAACTGAAAGAGACATTATTGCATTAGATTTTGAATTCACCCATATTTTCAGACCTACTATGATTGTTGGA
AATCGAAAAGATAAACGTCCGTTCGAAAAAATCGGAATGAAAATATGGAAACTTATTCATCCTGTTTTTATTGGCAGACA
GACTGATTACAAAGAAATCGACGCAAAAGAAATTGCAAAAGCAATGAATAACGCTTCTTTAAATCAGACAGAAAAAGTTA
AGATTTACAATTGGAAAGAGATGAAATTTTACTCTAATTCTAAAGAACAAATTACACTGGTATAA

Upstream 100 bases:

>100_bases
CACTTCTTGTTAGTCATATACCAGCTGATAAAATTCTTGAAATAAAAGAAAATAAAGTAATTGCAGAAAATATTGTTCAA
CTGCACTTTACAACAAAATA

Downstream 100 bases:

>100_bases
AAAAATAATGCTAAACTTTTTTCTCTAACTTAATTTTCTAAATGAAATAAAATGAGTCACATAATTTCTTAAGGCCCAAA
TTTAGTAGATTTGTATTAAT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSILENNKMKKAVLFGASGFVGSELLLKLLNNPIYEEVTIVVRKPLNSTHSKLRILIGDFNSMPGLIEKISADTVFIALG
AIQNSRQNSDEFYQIDHDYPVIAAKILKENGAKSVFLVTAAGANPNSKFRYIKTKGETERDIIALDFEFTHIFRPTMIVG
NRKDKRPFEKIGMKIWKLIHPVFIGRQTDYKEIDAKEIAKAMNNASLNQTEKVKIYNWKEMKFYSNSKEQITLV

Sequences:

>Translated_234_residues
MSILENNKMKKAVLFGASGFVGSELLLKLLNNPIYEEVTIVVRKPLNSTHSKLRILIGDFNSMPGLIEKISADTVFIALG
AIQNSRQNSDEFYQIDHDYPVIAAKILKENGAKSVFLVTAAGANPNSKFRYIKTKGETERDIIALDFEFTHIFRPTMIVG
NRKDKRPFEKIGMKIWKLIHPVFIGRQTDYKEIDAKEIAKAMNNASLNQTEKVKIYNWKEMKFYSNSKEQITLV
>Mature_233_residues
SILENNKMKKAVLFGASGFVGSELLLKLLNNPIYEEVTIVVRKPLNSTHSKLRILIGDFNSMPGLIEKISADTVFIALGA
IQNSRQNSDEFYQIDHDYPVIAAKILKENGAKSVFLVTAAGANPNSKFRYIKTKGETERDIIALDFEFTHIFRPTMIVGN
RKDKRPFEKIGMKIWKLIHPVFIGRQTDYKEIDAKEIAKAMNNASLNQTEKVKIYNWKEMKFYSNSKEQITLV

Specific function: Unknown

COG id: COG0702

COG function: function code MG; Predicted nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YER004W [H]

Homologues:

Organism=Homo sapiens, GI148728172, Length=164, Percent_Identity=28.0487804878049, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI148728168, Length=164, Percent_Identity=28.0487804878049, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI148728164, Length=164, Percent_Identity=28.0487804878049, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI148728166, Length=164, Percent_Identity=28.0487804878049, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI87082218, Length=221, Percent_Identity=28.9592760180996, Blast_Score=94, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71983631, Length=222, Percent_Identity=37.3873873873874, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6320840, Length=231, Percent_Identity=28.1385281385281, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF01118 Semialdhyde_dh [H]

EC number: NA

Molecular weight: Translated: 26661; Mature: 26530

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILENNKMKKAVLFGASGFVGSELLLKLLNNPIYEEVTIVVRKPLNSTHSKLRILIGDF
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCEEEEEEECC
NSMPGLIEKISADTVFIALGAIQNSRQNSDEFYQIDHDYPVIAAKILKENGAKSVFLVTA
CCCCHHHHHHCCCEEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCEEEEEEE
AGANPNSKFRYIKTKGETERDIIALDFEFTHIFRPTMIVGNRKDKRPFEKIGMKIWKLIH
ECCCCCCCEEEEEECCCCCCCEEEEEEEEHHHCCCEEEECCCCCCCHHHHHHHHHHHHHH
PVFIGRQTDYKEIDAKEIAKAMNNASLNQTEKVKIYNWKEMKFYSNSKEQITLV
HHHCCCCCCHHHCCHHHHHHHHCCCCCCCCCEEEEEEEEEEEEECCCCCEEEEC
>Mature Secondary Structure 
SILENNKMKKAVLFGASGFVGSELLLKLLNNPIYEEVTIVVRKPLNSTHSKLRILIGDF
CCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCEEEEEEECC
NSMPGLIEKISADTVFIALGAIQNSRQNSDEFYQIDHDYPVIAAKILKENGAKSVFLVTA
CCCCHHHHHHCCCEEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCEEEEEEE
AGANPNSKFRYIKTKGETERDIIALDFEFTHIFRPTMIVGNRKDKRPFEKIGMKIWKLIH
ECCCCCCCEEEEEECCCCCCCEEEEEEEEHHHCCCEEEECCCCCCCHHHHHHHHHHHHHH
PVFIGRQTDYKEIDAKEIAKAMNNASLNQTEKVKIYNWKEMKFYSNSKEQITLV
HHHCCCCCCHHHCCHHHHHHHHCCCCCCCCCEEEEEEEEEEEEECCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]