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The map label for this gene is arsB [H]

Identifier: 146302154

GI number: 146302154

Start: 5332259

End: 5333344

Strand: Direct

Name: arsB [H]

Synonym: Fjoh_4422

Alternate gene names: 146302154

Gene position: 5332259-5333344 (Clockwise)

Preceding gene: 146302153

Following gene: 146302155

Centisome position: 87.46

GC content: 40.98

Gene sequence:

>1086_bases
ATGTCAGCAAATAATTGTGCACCAGCCGTCGGACGCAAAAAGTTAAGCTTCCTTGACCGCTTCTTAACCCTTTGGATTTT
CCTTGCTATGGCTATAGGCGTGGCAATAGGATACTTTATTCCTTCAAGCGGAGGTTTCATCAATTCATTCTCCAGCGGAA
CAACAAACATTCCATTGGCAATAGGACTTATCCTGATGATGTATCCGCCTCTGGCAAAAGTAAAATACGAGCAGATGGGT
CAGGTTTTCAAAAACACTAAAGTCTTAGGCGCTTCTTTATTCCTGAACTGGATCGTAGGCCCTGTCTTAATGTTTTTATT
GGCGCTCCTGTTTTTGAACGGATATCCTGAATACATGATTGGAGTGATCCTGATCGGTCTGGCACGCTGTATCGCAATGG
TTGTGGTATGGAACGATCTGGCAGACGGAAACCGTGAGTATGCAGCAGGACTTATCGCACTTAACAGTATTTTTCAGGTG
CTGCTTTATAGCGTATATGCATACATTTTTATAACCATTCTACCTCCCTATTTTGGATATGATGGCTTCGAAGTCAATAT
CAGCATTTCACAGATTGCCGAGAGCGTCGGTATCTATTTAGGTATTCCATTTGCTCTGGGAATCATAAGCCGTTATGCTT
TGATAGCCTTAAAAGGTTCTGAATGGTTTGAGAATAAGTACGTGCCGTTTATCTCGCCAATTACACTTATTTCGTTGCTC
TTTACAATTATTGTAATGTTTAGCCTGAAAGGGGAACTTATTATTCAGATCCCTATGGATGTCGTGCGTATTGCAATACC
GCTTGTGATTTACTTTACTTTAATGTTTATCATCAGTTTTTTCACTGGAAAATATTTTGGGGCTGACTATTCAAAGGCTA
CATCTATAGCTTTTACAGCCACCGGAAATAATTTTGAACTTGCCATTGCCGTGGCAATCGGCGTGTTTGGAATAAACAGC
GGCCAGGCATTTGCAGGTGTTATAGGTCCTTTGGTAGAAGTACCTGCTCTTATAGCATTAGTAAACCTTGCATTCTGGTT
CAGAAAGAAGTATTTCACAAAACAGGTATCTGCAGAAACTGCTTAA

Upstream 100 bases:

>100_bases
ATTTCTGACGGAACGCCTCAGCAGAAGGAAACTTATCTGGAGCGAAGCCTGCAGATAGGAACTGAAATGTTTTACGTATT
CTCACAAATAAAAAAATAAA

Downstream 100 bases:

>100_bases
AAAAATATGAGAATTGCAATAATATCGGATATACATGCGAACTTCCCCGCATTGGAGCAGACCTTAAAAAGTATTGAAGA
GCAGAATATTGATGCTGTTT

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSANNCAPAVGRKKLSFLDRFLTLWIFLAMAIGVAIGYFIPSSGGFINSFSSGTTNIPLAIGLILMMYPPLAKVKYEQMG
QVFKNTKVLGASLFLNWIVGPVLMFLLALLFLNGYPEYMIGVILIGLARCIAMVVVWNDLADGNREYAAGLIALNSIFQV
LLYSVYAYIFITILPPYFGYDGFEVNISISQIAESVGIYLGIPFALGIISRYALIALKGSEWFENKYVPFISPITLISLL
FTIIVMFSLKGELIIQIPMDVVRIAIPLVIYFTLMFIISFFTGKYFGADYSKATSIAFTATGNNFELAIAVAIGVFGINS
GQAFAGVIGPLVEVPALIALVNLAFWFRKKYFTKQVSAETA

Sequences:

>Translated_361_residues
MSANNCAPAVGRKKLSFLDRFLTLWIFLAMAIGVAIGYFIPSSGGFINSFSSGTTNIPLAIGLILMMYPPLAKVKYEQMG
QVFKNTKVLGASLFLNWIVGPVLMFLLALLFLNGYPEYMIGVILIGLARCIAMVVVWNDLADGNREYAAGLIALNSIFQV
LLYSVYAYIFITILPPYFGYDGFEVNISISQIAESVGIYLGIPFALGIISRYALIALKGSEWFENKYVPFISPITLISLL
FTIIVMFSLKGELIIQIPMDVVRIAIPLVIYFTLMFIISFFTGKYFGADYSKATSIAFTATGNNFELAIAVAIGVFGINS
GQAFAGVIGPLVEVPALIALVNLAFWFRKKYFTKQVSAETA
>Mature_360_residues
SANNCAPAVGRKKLSFLDRFLTLWIFLAMAIGVAIGYFIPSSGGFINSFSSGTTNIPLAIGLILMMYPPLAKVKYEQMGQ
VFKNTKVLGASLFLNWIVGPVLMFLLALLFLNGYPEYMIGVILIGLARCIAMVVVWNDLADGNREYAAGLIALNSIFQVL
LYSVYAYIFITILPPYFGYDGFEVNISISQIAESVGIYLGIPFALGIISRYALIALKGSEWFENKYVPFISPITLISLLF
TIIVMFSLKGELIIQIPMDVVRIAIPLVIYFTLMFIISFFTGKYFGADYSKATSIAFTATGNNFELAIAVAIGVFGINSG
QAFAGVIGPLVEVPALIALVNLAFWFRKKYFTKQVSAETA

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=366, Percent_Identity=34.4262295081967, Blast_Score=176, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 39584; Mature: 39453

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANNCAPAVGRKKLSFLDRFLTLWIFLAMAIGVAIGYFIPSSGGFINSFSSGTTNIPLA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
IGLILMMYPPLAKVKYEQMGQVFKNTKVLGASLFLNWIVGPVLMFLLALLFLNGYPEYMI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GVILIGLARCIAMVVVWNDLADGNREYAAGLIALNSIFQVLLYSVYAYIFITILPPYFGY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCC
DGFEVNISISQIAESVGIYLGIPFALGIISRYALIALKGSEWFENKYVPFISPITLISLL
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHCCCCCCCCCHHHHHHHH
FTIIVMFSLKGELIIQIPMDVVRIAIPLVIYFTLMFIISFFTGKYFGADYSKATSIAFTA
HHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
TGNNFELAIAVAIGVFGINSGQAFAGVIGPLVEVPALIALVNLAFWFRKKYFTKQVSAET
ECCCEEEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
A
C
>Mature Secondary Structure 
SANNCAPAVGRKKLSFLDRFLTLWIFLAMAIGVAIGYFIPSSGGFINSFSSGTTNIPLA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
IGLILMMYPPLAKVKYEQMGQVFKNTKVLGASLFLNWIVGPVLMFLLALLFLNGYPEYMI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GVILIGLARCIAMVVVWNDLADGNREYAAGLIALNSIFQVLLYSVYAYIFITILPPYFGY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCC
DGFEVNISISQIAESVGIYLGIPFALGIISRYALIALKGSEWFENKYVPFISPITLISLL
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHCCCCCCCCCHHHHHHHH
FTIIVMFSLKGELIIQIPMDVVRIAIPLVIYFTLMFIISFFTGKYFGADYSKATSIAFTA
HHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
TGNNFELAIAVAIGVFGINSGQAFAGVIGPLVEVPALIALVNLAFWFRKKYFTKQVSAET
ECCCEEEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]