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The map label for this gene is erg3 [H]

Identifier: 146302069

GI number: 146302069

Start: 5237271

End: 5238494

Strand: Reverse

Name: erg3 [H]

Synonym: Fjoh_4333

Alternate gene names: 146302069

Gene position: 5238494-5237271 (Counterclockwise)

Preceding gene: 146302070

Following gene: 146302067

Centisome position: 85.92

GC content: 33.01

Gene sequence:

>1224_bases
ATGAAAAATATTAATTTTCTAGCTTTTGCAATGCCCGCTTTCTTTCTTTTTTTATTTCTGGAATATAAGCTGGCACAACG
AAAAAAAAGACCTGAAATTTTTAATTATGAAAGTTCTGTTTCTAATATAAGTATTGGTATTGCAGAACGATTGATTAATT
TATTTGTTGCCGCAAGTTTTTATCAATTGTATTATTTGATTTACGACGAGTATCGAATTTTTGAAATCCCAAGCGGATTT
CTGGTCTGGACTGCATTGATTCTGGCAACAGATTTTGTTTGGTACTGGTATCACAGACTAGGGCACGAAGTCAATTTTTT
CTGGGCTGCACATATTGTTCACCATCACAGCGAAGAATTTAATTTTACCGCTGCAGCCAGAATTACTACTTTTCAGGCTG
TTATTCGAACGGGATTTTGGTGTATTCTGCCATTAATTGGTTTTCACCCCACAATGGTAATTACCATGCTTATTGTGCAT
GGCGCTTATTCTTTTTTTACCCATACACAGCTTATTGGTAAAATAAAATGGCTGGAGTATATTTTTGTAACGCCTTCAAT
TCACGGTGTTCATCATGCTTCTGATGAAAAATATCTCGATAAAAATTACGGAGATATGTTTACTTTTTGGGACCGTCTTT
TTGGTACTTTTCAGGAAGAAGAAGAAAAACCCAAATACGGATTAACACATCCGCTGAAAAGTTACAGTTTCCTTTGGCAG
CATTTTCATTATTATTTTGAAATATACGAGTTATGGAAACGCTCAAAAGGTTTTAAAGCAAGATGGCAGGCCGTTTTTGG
AAGTCCGGCAAATATGGATCAGGATATTCGTCCAATATTAGAAAAACGATTTTTGCAGGATAAAAGCAATCCGCATCAAA
GGCTTCGTTTTAGAAATTATCTTTATATCCAATTGGCTCTTTGCACTTTACTTCTTACGGTTTTTACCTATTATTTTGAT
AATTTAGAAATCTATGATAAAGTTTTTGTTCTATCAATCACCATTATCACTTTAATTAACTGCGGTGCAATATTAGAACA
GCGAAAATGGATTTATTATCTTGAATACACTCGTATTTTTATGATAACAACTTATTTTTTATATGAAGAAAATCTAATCA
TGTTTTTCTTTGTTCCGCTCGCCATTATGATTTTCGCTGAACAATTGTTTTCGCTTAGTAAATATTATCAAAATATGATT
CTGCAGTTGGAAAATGTTGAATAA

Upstream 100 bases:

>100_bases
TATCATGTCATAAAACAGCAGATATTGATTGATGAAATTGTCTTTTTAATTCAATTAGTTGTTTTTAGTTCTTTAAAAAT
CAATAAAGTAATCTTTAAAA

Downstream 100 bases:

>100_bases
GAGTTTTCACCGCGAATTCACGAATTATTTTAATTCATGATATCCCAGCGGGATGAAATATTTGTAGAAAAAATTGATGT
TTATACAGCAAAGCTCCAGC

Product: sterol desaturase-like protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKNINFLAFAMPAFFLFLFLEYKLAQRKKRPEIFNYESSVSNISIGIAERLINLFVAASFYQLYYLIYDEYRIFEIPSGF
LVWTALILATDFVWYWYHRLGHEVNFFWAAHIVHHHSEEFNFTAAARITTFQAVIRTGFWCILPLIGFHPTMVITMLIVH
GAYSFFTHTQLIGKIKWLEYIFVTPSIHGVHHASDEKYLDKNYGDMFTFWDRLFGTFQEEEEKPKYGLTHPLKSYSFLWQ
HFHYYFEIYELWKRSKGFKARWQAVFGSPANMDQDIRPILEKRFLQDKSNPHQRLRFRNYLYIQLALCTLLLTVFTYYFD
NLEIYDKVFVLSITIITLINCGAILEQRKWIYYLEYTRIFMITTYFLYEENLIMFFFVPLAIMIFAEQLFSLSKYYQNMI
LQLENVE

Sequences:

>Translated_407_residues
MKNINFLAFAMPAFFLFLFLEYKLAQRKKRPEIFNYESSVSNISIGIAERLINLFVAASFYQLYYLIYDEYRIFEIPSGF
LVWTALILATDFVWYWYHRLGHEVNFFWAAHIVHHHSEEFNFTAAARITTFQAVIRTGFWCILPLIGFHPTMVITMLIVH
GAYSFFTHTQLIGKIKWLEYIFVTPSIHGVHHASDEKYLDKNYGDMFTFWDRLFGTFQEEEEKPKYGLTHPLKSYSFLWQ
HFHYYFEIYELWKRSKGFKARWQAVFGSPANMDQDIRPILEKRFLQDKSNPHQRLRFRNYLYIQLALCTLLLTVFTYYFD
NLEIYDKVFVLSITIITLINCGAILEQRKWIYYLEYTRIFMITTYFLYEENLIMFFFVPLAIMIFAEQLFSLSKYYQNMI
LQLENVE
>Mature_407_residues
MKNINFLAFAMPAFFLFLFLEYKLAQRKKRPEIFNYESSVSNISIGIAERLINLFVAASFYQLYYLIYDEYRIFEIPSGF
LVWTALILATDFVWYWYHRLGHEVNFFWAAHIVHHHSEEFNFTAAARITTFQAVIRTGFWCILPLIGFHPTMVITMLIVH
GAYSFFTHTQLIGKIKWLEYIFVTPSIHGVHHASDEKYLDKNYGDMFTFWDRLFGTFQEEEEKPKYGLTHPLKSYSFLWQ
HFHYYFEIYELWKRSKGFKARWQAVFGSPANMDQDIRPILEKRFLQDKSNPHQRLRFRNYLYIQLALCTLLLTVFTYYFD
NLEIYDKVFVLSITIITLINCGAILEQRKWIYYLEYTRIFMITTYFLYEENLIMFFFVPLAIMIFAEQLFSLSKYYQNMI
LQLENVE

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=369, Percent_Identity=30.3523035230352, Blast_Score=172, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI25144659, Length=384, Percent_Identity=23.6979166666667, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 49107; Mature: 49107

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNINFLAFAMPAFFLFLFLEYKLAQRKKRPEIFNYESSVSNISIGIAERLINLFVAASF
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YQLYYLIYDEYRIFEIPSGFLVWTALILATDFVWYWYHRLGHEVNFFWAAHIVHHHSEEF
HHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
NFTAAARITTFQAVIRTGFWCILPLIGFHPTMVITMLIVHGAYSFFTHTQLIGKIKWLEY
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
IFVTPSIHGVHHASDEKYLDKNYGDMFTFWDRLFGTFQEEEEKPKYGLTHPLKSYSFLWQ
EEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCHHHHHCCCCCCCCCCHHHHHHHHH
HFHYYFEIYELWKRSKGFKARWQAVFGSPANMDQDIRPILEKRFLQDKSNPHQRLRFRNY
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
LYIQLALCTLLLTVFTYYFDNLEIYDKVFVLSITIITLINCGAILEQRKWIYYLEYTRIF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHH
MITTYFLYEENLIMFFFVPLAIMIFAEQLFSLSKYYQNMILQLENVE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNINFLAFAMPAFFLFLFLEYKLAQRKKRPEIFNYESSVSNISIGIAERLINLFVAASF
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YQLYYLIYDEYRIFEIPSGFLVWTALILATDFVWYWYHRLGHEVNFFWAAHIVHHHSEEF
HHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
NFTAAARITTFQAVIRTGFWCILPLIGFHPTMVITMLIVHGAYSFFTHTQLIGKIKWLEY
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
IFVTPSIHGVHHASDEKYLDKNYGDMFTFWDRLFGTFQEEEEKPKYGLTHPLKSYSFLWQ
EEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCHHHHHCCCCCCCCCCHHHHHHHHH
HFHYYFEIYELWKRSKGFKARWQAVFGSPANMDQDIRPILEKRFLQDKSNPHQRLRFRNY
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
LYIQLALCTLLLTVFTYYFDNLEIYDKVFVLSITIITLINCGAILEQRKWIYYLEYTRIF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHH
MITTYFLYEENLIMFFFVPLAIMIFAEQLFSLSKYYQNMILQLENVE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]