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The map label for this gene is exuT [H]

Identifier: 146302001

GI number: 146302001

Start: 5151468

End: 5152937

Strand: Reverse

Name: exuT [H]

Synonym: Fjoh_4265

Alternate gene names: 146302001

Gene position: 5152937-5151468 (Counterclockwise)

Preceding gene: 146302003

Following gene: 146302000

Centisome position: 84.52

GC content: 35.99

Gene sequence:

>1470_bases
ATGAGTCAAACCGATGCTGTTACAGTAAATCAAACCGTTAAGTCCGCAGGAAGATATCGTTGGAGTATATGTGCTCTGCT
TTTTTTTGCAACCACTATTAATTATCTCGACAGACAAGTTTTGTCTTTAACTTGGAGTGATTTTATTGCACCGGAATTTC
ATTGGACAAATAACGATTATGGAAATATCACGGCTTTATTTTCTATTTTTTATGCCGTTTCTTTATTATTCGCAGGAAGA
TTTATAGACTGGATGGATACTAAAAAAGGATTTCTGTGGGCAATTGGAATTTGGTCTATAGGAGCTTGTTTACATGCATT
TTGCGGTATCGCTACTTCTGGAATTATTACAGGAAACTGGCTGGTAGGATTTCATGGATCAAAAGAAATTATAAGTACAA
TAAACGACACGGGACTTGTAATTAATGTAAGTGTAGCTTTGTTTATTTTTGCTCGTTTTGTTTTGGCAGTAGGAGAAGCT
GGAAACTTTCCTGCAGCAATTAAAACTACAGCAGAATATTTTCCTAAAAAAGACAGAGCATTTTCTACAAGTATATTTAA
CGCTGGTGCCACAGTTGGTGCATTGGCAGCTCCAATTACAATTCCGTTTATTGCTAAATCATTTGGATGGGAAATGTCTT
TCATCATTATTGGAGCATTAGGTTTTATATGGATGGGATTCTGGGTTTTCATGTACGATAAACCAGAAAGACACCCAAGA
GTAAGTCCTGAAGAATTAGCTTATATTCAGCAGGATGATATTGCAGACAGCAAATTAGAAGGTTATGTTCCGGAAACAAC
TTCAAAAGTTTCATTTGTAGACTGTTTTAAATACAAACAAACCTGGGCTTTTGCTTTTGGTAAATTTATGACAGATGGTG
TTTGGTGGTTTTTCTTATTCTGGACTCCGGCTTATTTAAGCTCAGTTTACGGAATGGATTCTACAGAAGCAGCTTTACCA
TTATTTGTTTTATACATGATTACATTATTATCAATTATTGGCGGCTGGCTTCCAACTTATTTTGTAGAAAAGAAAGGAAT
GAACCCATACGAAGGAAGAATGCGAGCGATGTTAATTTTTGCTTTCTTCCCATTGCTGGCCTTAATTGCACAACCGTTAG
GATATATCAGTTACTGGGTTCCGGTAATCATCATCGGAATTGCAGGAGCGGCACACCAGTCTTGGTCGGCAAATATTTTT
ACAACAGTAGGAGATATGTTCCCTAAAAAAGCTATTGCAACAATTACAGGAATTGGTGGTTTAGCAGGAGGAGTAGGATC
TACTTTAATCAATAAAGGCTCTGGAGTTTTGTTTGATTATGCTAAAGAAACTGAAATGGTTTTTATGGGATTCAAAGGAA
TAGAGGCAGGATATTTTATCATTTTCTCTATTTGTGCTGTATGTTATTTAACAGGATGGATTGTAATGAAATCTTTAGTT
CCTAGATACAGTCCGATCACAAATTTGTAA

Upstream 100 bases:

>100_bases
GTTTTATAAAATTAAAATATTGATTTTAATGTGTTTAAATTATGCGTAGTGTGTATAAGATTTTTCCAAAAAAAATATCT
AACTATAATAACCCGTTACC

Downstream 100 bases:

>100_bases
TGGATAATTTTTCTAAATAGAATAATTTTTTCATTTGAATTATGGTTTTTCAATATAAAAAATTAATTTTGTGCAATCGA
TTACATTAAACAAAAATTAT

Product: major facilitator transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSQTDAVTVNQTVKSAGRYRWSICALLFFATTINYLDRQVLSLTWSDFIAPEFHWTNNDYGNITALFSIFYAVSLLFAGR
FIDWMDTKKGFLWAIGIWSIGACLHAFCGIATSGIITGNWLVGFHGSKEIISTINDTGLVINVSVALFIFARFVLAVGEA
GNFPAAIKTTAEYFPKKDRAFSTSIFNAGATVGALAAPITIPFIAKSFGWEMSFIIIGALGFIWMGFWVFMYDKPERHPR
VSPEELAYIQQDDIADSKLEGYVPETTSKVSFVDCFKYKQTWAFAFGKFMTDGVWWFFLFWTPAYLSSVYGMDSTEAALP
LFVLYMITLLSIIGGWLPTYFVEKKGMNPYEGRMRAMLIFAFFPLLALIAQPLGYISYWVPVIIIGIAGAAHQSWSANIF
TTVGDMFPKKAIATITGIGGLAGGVGSTLINKGSGVLFDYAKETEMVFMGFKGIEAGYFIIFSICAVCYLTGWIVMKSLV
PRYSPITNL

Sequences:

>Translated_489_residues
MSQTDAVTVNQTVKSAGRYRWSICALLFFATTINYLDRQVLSLTWSDFIAPEFHWTNNDYGNITALFSIFYAVSLLFAGR
FIDWMDTKKGFLWAIGIWSIGACLHAFCGIATSGIITGNWLVGFHGSKEIISTINDTGLVINVSVALFIFARFVLAVGEA
GNFPAAIKTTAEYFPKKDRAFSTSIFNAGATVGALAAPITIPFIAKSFGWEMSFIIIGALGFIWMGFWVFMYDKPERHPR
VSPEELAYIQQDDIADSKLEGYVPETTSKVSFVDCFKYKQTWAFAFGKFMTDGVWWFFLFWTPAYLSSVYGMDSTEAALP
LFVLYMITLLSIIGGWLPTYFVEKKGMNPYEGRMRAMLIFAFFPLLALIAQPLGYISYWVPVIIIGIAGAAHQSWSANIF
TTVGDMFPKKAIATITGIGGLAGGVGSTLINKGSGVLFDYAKETEMVFMGFKGIEAGYFIIFSICAVCYLTGWIVMKSLV
PRYSPITNL
>Mature_488_residues
SQTDAVTVNQTVKSAGRYRWSICALLFFATTINYLDRQVLSLTWSDFIAPEFHWTNNDYGNITALFSIFYAVSLLFAGRF
IDWMDTKKGFLWAIGIWSIGACLHAFCGIATSGIITGNWLVGFHGSKEIISTINDTGLVINVSVALFIFARFVLAVGEAG
NFPAAIKTTAEYFPKKDRAFSTSIFNAGATVGALAAPITIPFIAKSFGWEMSFIIIGALGFIWMGFWVFMYDKPERHPRV
SPEELAYIQQDDIADSKLEGYVPETTSKVSFVDCFKYKQTWAFAFGKFMTDGVWWFFLFWTPAYLSSVYGMDSTEAALPL
FVLYMITLLSIIGGWLPTYFVEKKGMNPYEGRMRAMLIFAFFPLLALIAQPLGYISYWVPVIIIGIAGAAHQSWSANIFT
TVGDMFPKKAIATITGIGGLAGGVGSTLINKGSGVLFDYAKETEMVFMGFKGIEAGYFIIFSICAVCYLTGWIVMKSLVP
RYSPITNL

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=321, Percent_Identity=23.0529595015576, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI9966811, Length=294, Percent_Identity=22.108843537415, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI148743791, Length=366, Percent_Identity=22.1311475409836, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI2367193, Length=425, Percent_Identity=27.2941176470588, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789515, Length=473, Percent_Identity=24.3128964059197, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1789152, Length=337, Percent_Identity=27.0029673590504, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI87082320, Length=338, Percent_Identity=25.4437869822485, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI2367379, Length=347, Percent_Identity=23.6311239193084, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI115533554, Length=201, Percent_Identity=25.3731343283582, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115533556, Length=201, Percent_Identity=25.3731343283582, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17552542, Length=278, Percent_Identity=26.6187050359712, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573708, Length=293, Percent_Identity=30.3754266211604, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573707, Length=293, Percent_Identity=30.3754266211604, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24584153, Length=362, Percent_Identity=21.5469613259669, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24580790, Length=289, Percent_Identity=22.8373702422145, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 54262; Mature: 54131

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTDAVTVNQTVKSAGRYRWSICALLFFATTINYLDRQVLSLTWSDFIAPEFHWTNNDY
CCCCCCEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
GNITALFSIFYAVSLLFAGRFIDWMDTKKGFLWAIGIWSIGACLHAFCGIATSGIITGNW
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCEEECCE
LVGFHGSKEIISTINDTGLVINVSVALFIFARFVLAVGEAGNFPAAIKTTAEYFPKKDRA
EEEECCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC
FSTSIFNAGATVGALAAPITIPFIAKSFGWEMSFIIIGALGFIWMGFWVFMYDKPERHPR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCC
VSPEELAYIQQDDIADSKLEGYVPETTSKVSFVDCFKYKQTWAFAFGKFMTDGVWWFFLF
CCHHHHHHHCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WTPAYLSSVYGMDSTEAALPLFVLYMITLLSIIGGWLPTYFVEKKGMNPYEGRMRAMLIF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AFFPLLALIAQPLGYISYWVPVIIIGIAGAAHQSWSANIFTTVGDMFPKKAIATITGIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCH
LAGGVGSTLINKGSGVLFDYAKETEMVFMGFKGIEAGYFIIFSICAVCYLTGWIVMKSLV
HHCHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
PRYSPITNL
CCCCCCCCC
>Mature Secondary Structure 
SQTDAVTVNQTVKSAGRYRWSICALLFFATTINYLDRQVLSLTWSDFIAPEFHWTNNDY
CCCCCEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
GNITALFSIFYAVSLLFAGRFIDWMDTKKGFLWAIGIWSIGACLHAFCGIATSGIITGNW
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCEEECCE
LVGFHGSKEIISTINDTGLVINVSVALFIFARFVLAVGEAGNFPAAIKTTAEYFPKKDRA
EEEECCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC
FSTSIFNAGATVGALAAPITIPFIAKSFGWEMSFIIIGALGFIWMGFWVFMYDKPERHPR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCC
VSPEELAYIQQDDIADSKLEGYVPETTSKVSFVDCFKYKQTWAFAFGKFMTDGVWWFFLF
CCHHHHHHHCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WTPAYLSSVYGMDSTEAALPLFVLYMITLLSIIGGWLPTYFVEKKGMNPYEGRMRAMLIF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AFFPLLALIAQPLGYISYWVPVIIIGIAGAAHQSWSANIFTTVGDMFPKKAIATITGIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCH
LAGGVGSTLINKGSGVLFDYAKETEMVFMGFKGIEAGYFIIFSICAVCYLTGWIVMKSLV
HHCHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
PRYSPITNL
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]