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The map label for this gene is uxaC

Identifier: 146301998

GI number: 146301998

Start: 5148306

End: 5149709

Strand: Reverse

Name: uxaC

Synonym: Fjoh_4262

Alternate gene names: 146301998

Gene position: 5149709-5148306 (Counterclockwise)

Preceding gene: 146301999

Following gene: 146301997

Centisome position: 84.46

GC content: 34.54

Gene sequence:

>1404_bases
ATGAGCGCAAATACATTCATACACGACAATTTTTTATTAGAAAATAAATACGCTGAAGAGTTATATCATAATTACTCTAA
AAATCAGCCGATTATTGATTACCATAATCACTTAAATCCGCAGTTTATTGCAGAGGACAAGATTTTTGATAACATTACGA
ATGTATGGATTAACGGCGATCATTACAAATGGCGTGCAATGCGTACGTTAGGAATCGATGAGCAGTTTGTAACAGGAAAC
GGTTCTGATAAAGATAAATTCTTAAACTGGGCAAAAACGGTTCCGTACACAATGCGTAATCCTTTGTACCACTGGACACA
TTTAGAATTAGCTCGTTATTTTGATATTTATGATCTGTTGAATGAAAAATCAGCTGAGAAAATTTATACAGAAACGACAG
AGAAAATAAATTCTCAGGCTTACAGCACGCAAAACCTTCTTAAAAAAGTAAACGCTGAATTGGTTTGTACTACAGAAGAT
CCAATTGACAGTTTAGAATTTCACAAAAAATTCGCTAACAATTCGACTGGAATTAAAATGAGTACGGCTTTCAGACCTGA
TAAAGCCATCTTAATTGCTAATGATGGTTATAATGCATATCTGGACACATTAGGGGATGTGTCCGGAGTTGCAATTAACA
CTTTTGCTGATTTACAAGCAGCATTAAGAAACAGAATTGAATTCTTTAATGCAAACGGATGTAAATTAAGTGATCACGGT
TTAGACCAAATTTATTTTGAAGATTTTACAGAATCTGAAATCAGTTCAATCTTCAAAAAGAAAAGAGAAAACAGAATTAT
AACGCCAGAAGAAGCTTTAAAATTCCAGAGTGCTGTTTTGATATTCTTATCAGAAACGTATCATGAGTTTGGATGGGTGC
AGCAATTTCACTTAGGTGCATTGCGTAACAATAATGCGCGTATGCACAGAATTTTAGGCCCAGATACAGGATGGGATTCT
ATTGGAGATTATCCGCAGGCACAAAAACTATCTAGTTTTTTAAATGCTTTAGACAGTAAAGATAAATTGACAAAAACAAT
TATCTACAACTTAAATCCAGCCGATAACGAAGTTATGGCTACGATGATTGGAAACTTCAACGACGGAAGCGTTCGCGGAA
AAGTACAATTTGGTTCTGGATGGTGGTTTTTAGATCAAAAAGACGGAATGACAAAGCAGTTAAATGCACTTTCTAATATG
GGATTAATCAGCTGTTTTGTTGGAATGCTTACAGATTCAAGAAGTTTCTTATCATTCCCAAGACACGAATATTTCAGACG
TATTTTATGTAATCTCCTTGGAGACGAAATCAAACGCGGAGAACTTCCAAATGATATGGAATGGATTGGAAAATTAGTTG
CTGACATTTCATACAACAACGCAAAAGAGTATTTCAAATTCTAA

Upstream 100 bases:

>100_bases
TTTTGTAAACGGGCATATTTTATATGTTGACGGTGGAATCCTGGCTACAATTGGAAAACCTTCAAACGAAGAATAATTCT
CAAATTATATTTAAAAAGAC

Downstream 100 bases:

>100_bases
TTTTTTTAACCATTAAGATAGTAAGAAAATTAAGTTTTTGATTTAATAAATAGTTACTTAAATAATAAAGATAATTAAGC
GTGTGGGCTTAATAAACTTA

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSANTFIHDNFLLENKYAEELYHNYSKNQPIIDYHNHLNPQFIAEDKIFDNITNVWINGDHYKWRAMRTLGIDEQFVTGN
GSDKDKFLNWAKTVPYTMRNPLYHWTHLELARYFDIYDLLNEKSAEKIYTETTEKINSQAYSTQNLLKKVNAELVCTTED
PIDSLEFHKKFANNSTGIKMSTAFRPDKAILIANDGYNAYLDTLGDVSGVAINTFADLQAALRNRIEFFNANGCKLSDHG
LDQIYFEDFTESEISSIFKKKRENRIITPEEALKFQSAVLIFLSETYHEFGWVQQFHLGALRNNNARMHRILGPDTGWDS
IGDYPQAQKLSSFLNALDSKDKLTKTIIYNLNPADNEVMATMIGNFNDGSVRGKVQFGSGWWFLDQKDGMTKQLNALSNM
GLISCFVGMLTDSRSFLSFPRHEYFRRILCNLLGDEIKRGELPNDMEWIGKLVADISYNNAKEYFKF

Sequences:

>Translated_467_residues
MSANTFIHDNFLLENKYAEELYHNYSKNQPIIDYHNHLNPQFIAEDKIFDNITNVWINGDHYKWRAMRTLGIDEQFVTGN
GSDKDKFLNWAKTVPYTMRNPLYHWTHLELARYFDIYDLLNEKSAEKIYTETTEKINSQAYSTQNLLKKVNAELVCTTED
PIDSLEFHKKFANNSTGIKMSTAFRPDKAILIANDGYNAYLDTLGDVSGVAINTFADLQAALRNRIEFFNANGCKLSDHG
LDQIYFEDFTESEISSIFKKKRENRIITPEEALKFQSAVLIFLSETYHEFGWVQQFHLGALRNNNARMHRILGPDTGWDS
IGDYPQAQKLSSFLNALDSKDKLTKTIIYNLNPADNEVMATMIGNFNDGSVRGKVQFGSGWWFLDQKDGMTKQLNALSNM
GLISCFVGMLTDSRSFLSFPRHEYFRRILCNLLGDEIKRGELPNDMEWIGKLVADISYNNAKEYFKF
>Mature_466_residues
SANTFIHDNFLLENKYAEELYHNYSKNQPIIDYHNHLNPQFIAEDKIFDNITNVWINGDHYKWRAMRTLGIDEQFVTGNG
SDKDKFLNWAKTVPYTMRNPLYHWTHLELARYFDIYDLLNEKSAEKIYTETTEKINSQAYSTQNLLKKVNAELVCTTEDP
IDSLEFHKKFANNSTGIKMSTAFRPDKAILIANDGYNAYLDTLGDVSGVAINTFADLQAALRNRIEFFNANGCKLSDHGL
DQIYFEDFTESEISSIFKKKRENRIITPEEALKFQSAVLIFLSETYHEFGWVQQFHLGALRNNNARMHRILGPDTGWDSI
GDYPQAQKLSSFLNALDSKDKLTKTIIYNLNPADNEVMATMIGNFNDGSVRGKVQFGSGWWFLDQKDGMTKQLNALSNMG
LISCFVGMLTDSRSFLSFPRHEYFRRILCNLLGDEIKRGELPNDMEWIGKLVADISYNNAKEYFKF

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family

Homologues:

Organism=Escherichia coli, GI2367192, Length=462, Percent_Identity=51.0822510822511, Blast_Score=505, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXAC_FLAJ1 (A5FC03)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001196589.1
- ProteinModelPortal:   A5FC03
- SMR:   A5FC03
- STRING:   A5FC03
- GeneID:   5092304
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_4262
- eggNOG:   COG1904
- HOGENOM:   HBG297087
- OMA:   AWAKTVP
- ProtClustDB:   CLSK2537943
- BioCyc:   FJOH376686:FJOH_4262-MONOMER
- HAMAP:   MF_00675
- InterPro:   IPR003766
- InterPro:   IPR023177
- Gene3D:   G3DSA:1.10.2020.10

Pfam domain/function: PF02614 UxaC

EC number: =5.3.1.12

Molecular weight: Translated: 53887; Mature: 53756

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANTFIHDNFLLENKYAEELYHNYSKNQPIIDYHNHLNPQFIAEDKIFDNITNVWINGD
CCCCCEEECCEEECHHHHHHHHHHHCCCCCEEECCCCCCCCEEEHHHHHHHHHEEEECCC
HYKWRAMRTLGIDEQFVTGNGSDKDKFLNWAKTVPYTMRNPLYHWTHLELARYFDIYDLL
CEEEEEEEEECCCCEEECCCCCCHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHH
NEKSAEKIYTETTEKINSQAYSTQNLLKKVNAELVCTTEDPIDSLEFHKKFANNSTGIKM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCEEE
STAFRPDKAILIANDGYNAYLDTLGDVSGVAINTFADLQAALRNRIEFFNANGCKLSDHG
EEEECCCCEEEEECCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHEECCCCCEECCCC
LDQIYFEDFTESEISSIFKKKRENRIITPEEALKFQSAVLIFLSETYHEFGWVQQFHLGA
CCHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNNNARMHRILGPDTGWDSIGDYPQAQKLSSFLNALDSKDKLTKTIIYNLNPADNEVMA
HCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHEEEEEEEECCCCCCHHHH
TMIGNFNDGSVRGKVQFGSGWWFLDQKDGMTKQLNALSNMGLISCFVGMLTDSRSFLSFP
HHHCCCCCCCEEEEEEECCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCH
RHEYFRRILCNLLGDEIKRGELPNDMEWIGKLVADISYNNAKEYFKF
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHCC
>Mature Secondary Structure 
SANTFIHDNFLLENKYAEELYHNYSKNQPIIDYHNHLNPQFIAEDKIFDNITNVWINGD
CCCCEEECCEEECHHHHHHHHHHHCCCCCEEECCCCCCCCEEEHHHHHHHHHEEEECCC
HYKWRAMRTLGIDEQFVTGNGSDKDKFLNWAKTVPYTMRNPLYHWTHLELARYFDIYDLL
CEEEEEEEEECCCCEEECCCCCCHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHH
NEKSAEKIYTETTEKINSQAYSTQNLLKKVNAELVCTTEDPIDSLEFHKKFANNSTGIKM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCEEE
STAFRPDKAILIANDGYNAYLDTLGDVSGVAINTFADLQAALRNRIEFFNANGCKLSDHG
EEEECCCCEEEEECCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHEECCCCCEECCCC
LDQIYFEDFTESEISSIFKKKRENRIITPEEALKFQSAVLIFLSETYHEFGWVQQFHLGA
CCHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNNNARMHRILGPDTGWDSIGDYPQAQKLSSFLNALDSKDKLTKTIIYNLNPADNEVMA
HCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHEEEEEEEECCCCCCHHHH
TMIGNFNDGSVRGKVQFGSGWWFLDQKDGMTKQLNALSNMGLISCFVGMLTDSRSFLSFP
HHHCCCCCCCEEEEEEECCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCH
RHEYFRRILCNLLGDEIKRGELPNDMEWIGKLVADISYNNAKEYFKF
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA