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The map label for this gene is luxQ [H]

Identifier: 146301979

GI number: 146301979

Start: 5113623

End: 5115584

Strand: Direct

Name: luxQ [H]

Synonym: Fjoh_4243

Alternate gene names: 146301979

Gene position: 5113623-5115584 (Clockwise)

Preceding gene: 146301978

Following gene: 146301993

Centisome position: 83.87

GC content: 39.86

Gene sequence:

>1962_bases
ATGCCTTATAATGAATCTGAACGCCTGGATATTCTAAAGCGTTACAGTAATATGCTGGAAGCTCTTCCGGGATATGCATT
TGATGATGCAACTTCCCTGGTATCCTATATCTGTGGTGTACCAATTGCCTACATTGCTTTTATTGACGAAAACCGCCAGT
GGTTCAAATCTGAAATTGGTCTTGGCTTTTCCATAGTGCCGCGTGAAATTACTTTCAGCCGTTACACTATCATGGATTCT
TCTCTGGTAGAAATTCAAGACACACTGCTCAACGAACGTTTTAAAGATGATCCTGATGTAAAAGGAGGTTTAAAAATACG
GTTTTATGCCGGAATGCCGCTTATTACGCCAGATGGTCACGCAGTCGGGGTTTTATGTGCTGCAGATCACGAGCCGCGCT
CACTCAATGAAAATCAAAAAAGGGCGCTTCATATCGTAGCACGCCATGTTATTACAACACTTGAACTTGGGATAAAAAAC
AACGAACTTCTCAGACAAAAAAAAATTGCCGAAAGTGCTGTACTGGCAAAAGAATCTTTTTTGGCTAATATGAGCCATGA
AATCAGGACACCTCTAAATGCTATTATCGGTTTTACTGAACTTTTGTCCGGAACACCGCTCGATAAACAACAGCAGGCTT
TTATACAGGATGTTCAGACAGCCGGGGAAAATCTTTTACTCATAGTGAATGATATACTGGATTTATCTAAAATTGAATCC
GGAGGACTTTCTCTGGAAAAACAGCCCTTTAATTTAAAAAAATCACTCCGCCATGTCTACGATCTTCTAAAAGTAAAAAC
TGCTGACGGTGTTGAATTTAACTTGTTTTTGGATGCCGAACTTCCTGATGTTATTACAGGCGATCAGGGAAGACTGAATC
AGATAATGGTAAATCTGGCAGGAAATGCTCTTAAATTTACAAATGAAGGTGAAGTGACCATTTCCGTGAAAAATAAAGGA
GAAACAGAGGATTCTTATACCATTCGGTTTTCTGTTAAAGATACCGGAATAGGTATTCCGAAGGAGCATCTTGAATCTAT
ATTTGAACGATTTACACAGGGTCAGGAAGACACTACAAGAAAATTTGGAGGCACTGGTCTGGGATTGAGTATTGTTAAAG
AGCTGGTAAAACTGCACGATTCAAAAATACAAGTTAAAAGCCGTGAAGGCGCAGGATCGGAATTTTTTTTCACAACGACG
TATAAAAAACCAGCCAATGTAAAAGAAAATCCTAAACTGCTTCCGGTAAATGATCTGGGCAGGCTTAAAATATTGCTTCT
TGAAGACAACCGCTTAAATCAGAAACTGGCACAAAACGTTATTGAAGGGTTTGGATTTGAGATTGATATTGCAGAAAATG
GAGATCAGGGTATAAAACTTCTTTCAGAAAACCAATATGATCTGGTATTAATGGATCTTCAGATGCCTGCAAGAGACGGT
TATCAAACTACGCATTACATTCGCAGTGAGCTCAAAAATGAAATTCCTATTATAGCCATGACAGCCCATTCTCTTGCTGA
CGAGCATCATCGTTGTCTGAATGCCGGAATGGACGGTTATGTGCCAAAACCCTTTAAACAGCATGAACTTCTTGAAGCCA
TTAAGCAAGCTTTGAAAAAGGATCGCCGCCCTTTGATTCCTTCTAAAGCAGATTTATCTGCAATTGAAAAAACTGACCGT
ATAAAACCTGGGTGGAAAAAAGAAGTTACCTCCCAGTTTATCCAGAAGGCTCCTGTAGAACTAAAAGAATTACAGCAGGC
TGTTTATCGTAAAGATTTCAGATCTGTACTGCAAACCGCAGAACAGCTTCAGGTATGGCTGCATCTTTTCCTGCTGGAGA
ACTTAAGCCAGACCCTCACCTCTATCGAAGATCAGGCCCGCAAAAAAGAATTCACTGCCGAAACTGCTGACAATCTTGAT
ATCCTGCACTGCAATATTGAGGAAATTATAAAAGAACTGTAA

Upstream 100 bases:

>100_bases
TGAATTATATAAGAAATACCGCATAAATATATAACTGTTAAAAATAGAATATTCGTAAATTTAAGACTTAATTTATCTGT
CATGAGAAATCCCTTTGTCC

Downstream 100 bases:

>100_bases
TTATTTTTTTACTGAATTTCTGGTCTGTTTCCTAAAACCTGCATATACCGCCTGAGCAACAATGAATCAATATTTTTTAA
TATAAACCGTTTTTTTGTTT

Product: GAF sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 653; Mature: 652

Protein sequence:

>653_residues
MPYNESERLDILKRYSNMLEALPGYAFDDATSLVSYICGVPIAYIAFIDENRQWFKSEIGLGFSIVPREITFSRYTIMDS
SLVEIQDTLLNERFKDDPDVKGGLKIRFYAGMPLITPDGHAVGVLCAADHEPRSLNENQKRALHIVARHVITTLELGIKN
NELLRQKKIAESAVLAKESFLANMSHEIRTPLNAIIGFTELLSGTPLDKQQQAFIQDVQTAGENLLLIVNDILDLSKIES
GGLSLEKQPFNLKKSLRHVYDLLKVKTADGVEFNLFLDAELPDVITGDQGRLNQIMVNLAGNALKFTNEGEVTISVKNKG
ETEDSYTIRFSVKDTGIGIPKEHLESIFERFTQGQEDTTRKFGGTGLGLSIVKELVKLHDSKIQVKSREGAGSEFFFTTT
YKKPANVKENPKLLPVNDLGRLKILLLEDNRLNQKLAQNVIEGFGFEIDIAENGDQGIKLLSENQYDLVLMDLQMPARDG
YQTTHYIRSELKNEIPIIAMTAHSLADEHHRCLNAGMDGYVPKPFKQHELLEAIKQALKKDRRPLIPSKADLSAIEKTDR
IKPGWKKEVTSQFIQKAPVELKELQQAVYRKDFRSVLQTAEQLQVWLHLFLLENLSQTLTSIEDQARKKEFTAETADNLD
ILHCNIEEIIKEL

Sequences:

>Translated_653_residues
MPYNESERLDILKRYSNMLEALPGYAFDDATSLVSYICGVPIAYIAFIDENRQWFKSEIGLGFSIVPREITFSRYTIMDS
SLVEIQDTLLNERFKDDPDVKGGLKIRFYAGMPLITPDGHAVGVLCAADHEPRSLNENQKRALHIVARHVITTLELGIKN
NELLRQKKIAESAVLAKESFLANMSHEIRTPLNAIIGFTELLSGTPLDKQQQAFIQDVQTAGENLLLIVNDILDLSKIES
GGLSLEKQPFNLKKSLRHVYDLLKVKTADGVEFNLFLDAELPDVITGDQGRLNQIMVNLAGNALKFTNEGEVTISVKNKG
ETEDSYTIRFSVKDTGIGIPKEHLESIFERFTQGQEDTTRKFGGTGLGLSIVKELVKLHDSKIQVKSREGAGSEFFFTTT
YKKPANVKENPKLLPVNDLGRLKILLLEDNRLNQKLAQNVIEGFGFEIDIAENGDQGIKLLSENQYDLVLMDLQMPARDG
YQTTHYIRSELKNEIPIIAMTAHSLADEHHRCLNAGMDGYVPKPFKQHELLEAIKQALKKDRRPLIPSKADLSAIEKTDR
IKPGWKKEVTSQFIQKAPVELKELQQAVYRKDFRSVLQTAEQLQVWLHLFLLENLSQTLTSIEDQARKKEFTAETADNLD
ILHCNIEEIIKEL
>Mature_652_residues
PYNESERLDILKRYSNMLEALPGYAFDDATSLVSYICGVPIAYIAFIDENRQWFKSEIGLGFSIVPREITFSRYTIMDSS
LVEIQDTLLNERFKDDPDVKGGLKIRFYAGMPLITPDGHAVGVLCAADHEPRSLNENQKRALHIVARHVITTLELGIKNN
ELLRQKKIAESAVLAKESFLANMSHEIRTPLNAIIGFTELLSGTPLDKQQQAFIQDVQTAGENLLLIVNDILDLSKIESG
GLSLEKQPFNLKKSLRHVYDLLKVKTADGVEFNLFLDAELPDVITGDQGRLNQIMVNLAGNALKFTNEGEVTISVKNKGE
TEDSYTIRFSVKDTGIGIPKEHLESIFERFTQGQEDTTRKFGGTGLGLSIVKELVKLHDSKIQVKSREGAGSEFFFTTTY
KKPANVKENPKLLPVNDLGRLKILLLEDNRLNQKLAQNVIEGFGFEIDIAENGDQGIKLLSENQYDLVLMDLQMPARDGY
QTTHYIRSELKNEIPIIAMTAHSLADEHHRCLNAGMDGYVPKPFKQHELLEAIKQALKKDRRPLIPSKADLSAIEKTDRI
KPGWKKEVTSQFIQKAPVELKELQQAVYRKDFRSVLQTAEQLQVWLHLFLLENLSQTLTSIEDQARKKEFTAETADNLDI
LHCNIEEIIKEL

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=381, Percent_Identity=34.3832020997375, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1789149, Length=397, Percent_Identity=31.7380352644836, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1788713, Length=375, Percent_Identity=33.3333333333333, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87081816, Length=368, Percent_Identity=31.25, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=37.0786516853933, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=31.390134529148, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=26.6932270916335, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788393, Length=210, Percent_Identity=30.952380952381, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=31.304347826087, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790436, Length=259, Percent_Identity=29.7297297297297, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=31.9327731092437, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788549, Length=233, Percent_Identity=25.7510729613734, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786784, Length=135, Percent_Identity=31.8518518518519, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=253, Percent_Identity=24.901185770751, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=32.2033898305085, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=31.9327731092437, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790861, Length=217, Percent_Identity=26.7281105990783, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1788279, Length=201, Percent_Identity=27.8606965174129, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=26.2443438914027, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=115, Percent_Identity=34.7826086956522, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322000, Length=123, Percent_Identity=35.7723577235772, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73715; Mature: 73584

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYNESERLDILKRYSNMLEALPGYAFDDATSLVSYICGVPIAYIAFIDENRQWFKSEIG
CCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEHEEECCCHHHHHHHHC
LGFSIVPREITFSRYTIMDSSLVEIQDTLLNERFKDDPDVKGGLKIRFYAGMPLITPDGH
CCEEEECCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEECCCCC
AVGVLCAADHEPRSLNENQKRALHIVARHVITTLELGIKNNELLRQKKIAESAVLAKESF
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LANMSHEIRTPLNAIIGFTELLSGTPLDKQQQAFIQDVQTAGENLLLIVNDILDLSKIES
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCC
GGLSLEKQPFNLKKSLRHVYDLLKVKTADGVEFNLFLDAELPDVITGDQGRLNQIMVNLA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHC
GNALKFTNEGEVTISVKNKGETEDSYTIRFSVKDTGIGIPKEHLESIFERFTQGQEDTTR
CCEEEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHH
KFGGTGLGLSIVKELVKLHDSKIQVKSREGAGSEFFFTTTYKKPANVKENPKLLPVNDLG
HCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCEEEECCCC
RLKILLLEDNRLNQKLAQNVIEGFGFEIDIAENGDQGIKLLSENQYDLVLMDLQMPARDG
CEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCEEEEEEEECCCCCC
YQTTHYIRSELKNEIPIIAMTAHSLADEHHRCLNAGMDGYVPKPFKQHELLEAIKQALKK
CHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
DRRPLIPSKADLSAIEKTDRIKPGWKKEVTSQFIQKAPVELKELQQAVYRKDFRSVLQTA
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EQLQVWLHLFLLENLSQTLTSIEDQARKKEFTAETADNLDILHCNIEEIIKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHC
>Mature Secondary Structure 
PYNESERLDILKRYSNMLEALPGYAFDDATSLVSYICGVPIAYIAFIDENRQWFKSEIG
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEHEEECCCHHHHHHHHC
LGFSIVPREITFSRYTIMDSSLVEIQDTLLNERFKDDPDVKGGLKIRFYAGMPLITPDGH
CCEEEECCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEECCCCC
AVGVLCAADHEPRSLNENQKRALHIVARHVITTLELGIKNNELLRQKKIAESAVLAKESF
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LANMSHEIRTPLNAIIGFTELLSGTPLDKQQQAFIQDVQTAGENLLLIVNDILDLSKIES
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCC
GGLSLEKQPFNLKKSLRHVYDLLKVKTADGVEFNLFLDAELPDVITGDQGRLNQIMVNLA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHC
GNALKFTNEGEVTISVKNKGETEDSYTIRFSVKDTGIGIPKEHLESIFERFTQGQEDTTR
CCEEEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHH
KFGGTGLGLSIVKELVKLHDSKIQVKSREGAGSEFFFTTTYKKPANVKENPKLLPVNDLG
HCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCEEEECCCC
RLKILLLEDNRLNQKLAQNVIEGFGFEIDIAENGDQGIKLLSENQYDLVLMDLQMPARDG
CEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCEEEEEEEECCCCCC
YQTTHYIRSELKNEIPIIAMTAHSLADEHHRCLNAGMDGYVPKPFKQHELLEAIKQALKK
CHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
DRRPLIPSKADLSAIEKTDRIKPGWKKEVTSQFIQKAPVELKELQQAVYRKDFRSVLQTA
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EQLQVWLHLFLLENLSQTLTSIEDQARKKEFTAETADNLDILHCNIEEIIKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7984107 [H]