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The map label for this gene is uxuA

Identifier: 146301927

GI number: 146301927

Start: 5031521

End: 5032705

Strand: Direct

Name: uxuA

Synonym: Fjoh_4191

Alternate gene names: 146301927

Gene position: 5031521-5032705 (Clockwise)

Preceding gene: 146301926

Following gene: 146301928

Centisome position: 82.53

GC content: 37.97

Gene sequence:

>1185_bases
ATGGAACAAACATTAAGATGGTTCGGACCAAATGATCCTGTTTCTTTACAAGATATTGCACAAACCGGAGCAACCGGAAT
TGTAACAGCTTTACACCATATTCCAAACGGAGAAGTTTGGAGTATTGATGAAATTATCAAAAGAAAAGTTGAAATCGAAC
ATCAGGACGGCGATCCTAAAAAAGGTGCTTCGGGATTAACGTGGTCAGTTGTAGAAAGTATTCCGGTTCATGAAGACATT
AAAAAACAGACTGGAAATTACATTCAATACATTGAAAATTATAAAGAAAGCATTCGTAATCTGGCTTTATGCGGTATCAA
ATGTGTGTGTTATAATTTCATGCCTGTTTTAGACTGGTCAAGAACTGATTTATCCTATACCGTTGAAGACGGATCAAAAG
CACTTCGTTTTGATATAAATGCATTTGCAGCTTTTGAATTGTTCATTTTAAAAAGACCAGGTGCCGAAAACGAATATTCT
GATGAACAAAAACAAAAAGCAAAAAGCTATTTTGAGGCGATGACTGCCGAAGATAAAGTTAAATTGCAGCAGAACATTCT
TGCCGGACTTCCGGGTGCCGAAGAAGCGTATACGGTTGAAGATTTCTTAGTAACCTTAAGTGCTTACAATCATATTGACA
GACAGGCTTTAAAGAATAATCTTTTTCATTTTTTAAAAGAAATTGTTCCGGTTGCAGAAAGCAAAGGCGTTTTAATGGCA
ATTCATCCAGACGATCCTCCTTACCCAATTTTAGGCCTGCCAAGAGTTGTAAGTACCGAAGAAGATTTGATCGAGTTAAT
GAACGCTGCTCCTTCTAAATCAAACGGGTTTACAATGTGTACAGGTTCTTACGGTGTTCGTGCCGATAATGATTTACCGG
GAATTGTAAGACGTCATGGCGATAAAATGAATTTCATCCATTTAAGAAGCACACAACGCGACGAAGAAGGAAGTTTTTAT
GAAGCCAATCACTTGGAAGGCGACGTTGATATGTACGAAGTTGTAAAAGCAATTCTTGAAGTTGAAAAAAGAAATAACAG
CAAATTACCAATGCGTCCGGATCACGGACACCAAATGCTGGATGATTTAAAGAAAAAAACAAATCCGGGTTATTCTGCTA
TCGGCCGTTTAAGAGGACTGGCAGAACTGCGCGGACTGGAATTAGGGATCAAACGATCTTTATAA

Upstream 100 bases:

>100_bases
CGATATGTCAAAATTCGTAACAGGAACTATCTTAAAAGTTGACGGCGGTTTTGCTGCAACAAGTATCTAAAAACTAACTC
ACAAAACAACATAATACAAA

Downstream 100 bases:

>100_bases
TTGGTTTTGACACCAAGGCGCTGAGACCCAAAGTTTTTTATTTTTTTTAATCCTTTTAATCTGTGGCTAAAAAAACTTCG
TGCCTTAGCGCGTTGGCGGC

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MEQTLRWFGPNDPVSLQDIAQTGATGIVTALHHIPNGEVWSIDEIIKRKVEIEHQDGDPKKGASGLTWSVVESIPVHEDI
KKQTGNYIQYIENYKESIRNLALCGIKCVCYNFMPVLDWSRTDLSYTVEDGSKALRFDINAFAAFELFILKRPGAENEYS
DEQKQKAKSYFEAMTAEDKVKLQQNILAGLPGAEEAYTVEDFLVTLSAYNHIDRQALKNNLFHFLKEIVPVAESKGVLMA
IHPDDPPYPILGLPRVVSTEEDLIELMNAAPSKSNGFTMCTGSYGVRADNDLPGIVRRHGDKMNFIHLRSTQRDEEGSFY
EANHLEGDVDMYEVVKAILEVEKRNNSKLPMRPDHGHQMLDDLKKKTNPGYSAIGRLRGLAELRGLELGIKRSL

Sequences:

>Translated_394_residues
MEQTLRWFGPNDPVSLQDIAQTGATGIVTALHHIPNGEVWSIDEIIKRKVEIEHQDGDPKKGASGLTWSVVESIPVHEDI
KKQTGNYIQYIENYKESIRNLALCGIKCVCYNFMPVLDWSRTDLSYTVEDGSKALRFDINAFAAFELFILKRPGAENEYS
DEQKQKAKSYFEAMTAEDKVKLQQNILAGLPGAEEAYTVEDFLVTLSAYNHIDRQALKNNLFHFLKEIVPVAESKGVLMA
IHPDDPPYPILGLPRVVSTEEDLIELMNAAPSKSNGFTMCTGSYGVRADNDLPGIVRRHGDKMNFIHLRSTQRDEEGSFY
EANHLEGDVDMYEVVKAILEVEKRNNSKLPMRPDHGHQMLDDLKKKTNPGYSAIGRLRGLAELRGLELGIKRSL
>Mature_394_residues
MEQTLRWFGPNDPVSLQDIAQTGATGIVTALHHIPNGEVWSIDEIIKRKVEIEHQDGDPKKGASGLTWSVVESIPVHEDI
KKQTGNYIQYIENYKESIRNLALCGIKCVCYNFMPVLDWSRTDLSYTVEDGSKALRFDINAFAAFELFILKRPGAENEYS
DEQKQKAKSYFEAMTAEDKVKLQQNILAGLPGAEEAYTVEDFLVTLSAYNHIDRQALKNNLFHFLKEIVPVAESKGVLMA
IHPDDPPYPILGLPRVVSTEEDLIELMNAAPSKSNGFTMCTGSYGVRADNDLPGIVRRHGDKMNFIHLRSTQRDEEGSFY
EANHLEGDVDMYEVVKAILEVEKRNNSKLPMRPDHGHQMLDDLKKKTNPGYSAIGRLRGLAELRGLELGIKRSL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family

Homologues:

Organism=Escherichia coli, GI1790778, Length=400, Percent_Identity=63, Blast_Score=529, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXUA_FLAJ1 (A5FC71)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001196518.1
- ProteinModelPortal:   A5FC71
- STRING:   A5FC71
- GeneID:   5093821
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_4191
- eggNOG:   COG1312
- HOGENOM:   HBG585927
- OMA:   VHEEIKT
- BioCyc:   FJOH376686:FJOH_4191-MONOMER
- HAMAP:   MF_00106
- InterPro:   IPR004628
- InterPro:   IPR013022
- Gene3D:   G3DSA:3.20.20.150
- PIRSF:   PIRSF016049
- TIGRFAMs:   TIGR00695

Pfam domain/function: PF03786 UxuA; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =4.2.1.8

Molecular weight: Translated: 44364; Mature: 44364

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTLRWFGPNDPVSLQDIAQTGATGIVTALHHIPNGEVWSIDEIIKRKVEIEHQDGDPK
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCEECHHHHHHHHHEEECCCCCCC
KGASGLTWSVVESIPVHEDIKKQTGNYIQYIENYKESIRNLALCGIKCVCYNFMPVLDWS
CCCCCCCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RTDLSYTVEDGSKALRFDINAFAAFELFILKRPGAENEYSDEQKQKAKSYFEAMTAEDKV
CCCCEEEECCCCCEEEEEHHHHEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHH
KLQQNILAGLPGAEEAYTVEDFLVTLSAYNHIDRQALKNNLFHFLKEIVPVAESKGVLMA
HHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
IHPDDPPYPILGLPRVVSTEEDLIELMNAAPSKSNGFTMCTGSYGVRADNDLPGIVRRHG
ECCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHCC
DKMNFIHLRSTQRDEEGSFYEANHLEGDVDMYEVVKAILEVEKRNNSKLPMRPDHGHQML
CCCEEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
DDLKKKTNPGYSAIGRLRGLAELRGLELGIKRSL
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEQTLRWFGPNDPVSLQDIAQTGATGIVTALHHIPNGEVWSIDEIIKRKVEIEHQDGDPK
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCEECHHHHHHHHHEEECCCCCCC
KGASGLTWSVVESIPVHEDIKKQTGNYIQYIENYKESIRNLALCGIKCVCYNFMPVLDWS
CCCCCCCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RTDLSYTVEDGSKALRFDINAFAAFELFILKRPGAENEYSDEQKQKAKSYFEAMTAEDKV
CCCCEEEECCCCCEEEEEHHHHEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHH
KLQQNILAGLPGAEEAYTVEDFLVTLSAYNHIDRQALKNNLFHFLKEIVPVAESKGVLMA
HHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
IHPDDPPYPILGLPRVVSTEEDLIELMNAAPSKSNGFTMCTGSYGVRADNDLPGIVRRHG
ECCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHCC
DKMNFIHLRSTQRDEEGSFYEANHLEGDVDMYEVVKAILEVEKRNNSKLPMRPDHGHQML
CCCEEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
DDLKKKTNPGYSAIGRLRGLAELRGLELGIKRSL
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA