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The map label for this gene is mocR [H]

Identifier: 146301874

GI number: 146301874

Start: 4973608

End: 4975020

Strand: Direct

Name: mocR [H]

Synonym: Fjoh_4138

Alternate gene names: 146301874

Gene position: 4973608-4975020 (Clockwise)

Preceding gene: 146301873

Following gene: 146301878

Centisome position: 81.58

GC content: 35.88

Gene sequence:

>1413_bases
ATGTTACGACCTTGGCAATTTGAAATTCATTTAGATAAAAAATCAGACAAAGCACTTTATCTGCAAATTGCCGATGCTAT
AATCAATGCGGTAAAATCCGGTAAATTAACCAGCGGAAATGCTTTACCCGGAAGCCGTCAGCTGGCAGGATTATTAAATG
TAAACCGAAACACGGTAATCGAAGCCTTAGATGTTTTAATTGCCGAAGGCTGGCTGATTACTGTAGATCGAAAAGGTACT
TTTATTGCTGATATTCTTCCTGAAACCAATTTCAATAAGAAAACAGAAACCAAAGCCAGCAGTACAATCGAAAACCCGAA
ACCCCATCTTGTTTTTGATGATGGACTTCCGGACAGCCGTCTCGCTCCTATGAACGATCTCGCACGTGCATACCGCGAAA
TATTCAACAGAAAATCACGCTGGCAGATTATGGGTTACAGCAATGAATTGGGAAATGTTGAATTTAGAAAAGCGATTGTG
CAAATGCTGAATTTTAAAAGAGGAATGAATGTTTCTCTTGATGAAATCTGCATAACTCGAGGAAGTCAAATGGCGATGTA
TCTCGCAGCGCATTGTTTACTTTCAAAAGGAGATTCTGTTATTATTGAAAATCCGGGATACAAACCTGCGTGGGAAGCTT
TTGAAAATGCCGGCGCGACTCTGCTTCCTGTGAATATTTTAAAAGATGGTTTAGATTTAGAAGAAGTTGAAAATCATCTC
AAAAACAATAAAGCCATAAAAGCGATTTACGTTACGCCTCATCATCAATTTCCAACTACCGTTACAATGAGTCTCAAAAA
GAGATTAAAACTTATCGAACTCTCTAATCAATACGGATTTACGATTATTGAAGATGATTATGATAATGAATTTCATTTTG
GGCAGAGACCAATTCTGCCAATTTCGAGTTACAGCAATGCTAAAAACTTTATTTATATTGGCACTTTAAGCAAAATTGTA
GCTCCTGCTCTGCGTATTGGGTATTTGGCCGCTTCTATTGAAAACATACAAAAAATTGCCCAGCATAGAAAAATAATAGA
CGTTCAGGGCGATAATATTATGGAAGAAGCTGTTTTAAATCTTATAAACGAAGGAAAAATTAAAAGGCATCTCAAAAAAA
CGAATTTAATTTACAAAGCCAAAAGAGATCATTTTGAAAAACTCTGTAAACTTCATTTAAAAGACAAAATTACTTTTACT
AAACCCGAAGGCGGTATGGCCTTTTGGATTGTTCCAAAGTCAGAAATCGATCTTCAAAAAGTCTGCAATGAATTATTAAA
AAAAGGAATAAAAATAATGAGTCCTGAAAAATTCAGTTTTGGAAATCCGGCTTCCGGTTTGCGTCTGGGATATGCTTCAT
TAACCGAAGAACAAATGGAAGAAGGCATTTTGTCACTTTCAAAATATTTATAA

Upstream 100 bases:

>100_bases
TTAAAGCCAAATTAAAAAAGAAATAACCTCAATTCTATAAAAGCTTTTGTAAATTTGGTCTGTCTCATTAATTCAATTTC
AACACAAAAAGACAGACCAG

Downstream 100 bases:

>100_bases
CCGAACCGGTTTATGATCGAAACAATCCAGTCTTATATCGCTTGTTTCTAGTTTTGCATCCAATAATTTACAATAGTTAT
TTTCGTTTTTCTCTACAAAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MLRPWQFEIHLDKKSDKALYLQIADAIINAVKSGKLTSGNALPGSRQLAGLLNVNRNTVIEALDVLIAEGWLITVDRKGT
FIADILPETNFNKKTETKASSTIENPKPHLVFDDGLPDSRLAPMNDLARAYREIFNRKSRWQIMGYSNELGNVEFRKAIV
QMLNFKRGMNVSLDEICITRGSQMAMYLAAHCLLSKGDSVIIENPGYKPAWEAFENAGATLLPVNILKDGLDLEEVENHL
KNNKAIKAIYVTPHHQFPTTVTMSLKKRLKLIELSNQYGFTIIEDDYDNEFHFGQRPILPISSYSNAKNFIYIGTLSKIV
APALRIGYLAASIENIQKIAQHRKIIDVQGDNIMEEAVLNLINEGKIKRHLKKTNLIYKAKRDHFEKLCKLHLKDKITFT
KPEGGMAFWIVPKSEIDLQKVCNELLKKGIKIMSPEKFSFGNPASGLRLGYASLTEEQMEEGILSLSKYL

Sequences:

>Translated_470_residues
MLRPWQFEIHLDKKSDKALYLQIADAIINAVKSGKLTSGNALPGSRQLAGLLNVNRNTVIEALDVLIAEGWLITVDRKGT
FIADILPETNFNKKTETKASSTIENPKPHLVFDDGLPDSRLAPMNDLARAYREIFNRKSRWQIMGYSNELGNVEFRKAIV
QMLNFKRGMNVSLDEICITRGSQMAMYLAAHCLLSKGDSVIIENPGYKPAWEAFENAGATLLPVNILKDGLDLEEVENHL
KNNKAIKAIYVTPHHQFPTTVTMSLKKRLKLIELSNQYGFTIIEDDYDNEFHFGQRPILPISSYSNAKNFIYIGTLSKIV
APALRIGYLAASIENIQKIAQHRKIIDVQGDNIMEEAVLNLINEGKIKRHLKKTNLIYKAKRDHFEKLCKLHLKDKITFT
KPEGGMAFWIVPKSEIDLQKVCNELLKKGIKIMSPEKFSFGNPASGLRLGYASLTEEQMEEGILSLSKYL
>Mature_470_residues
MLRPWQFEIHLDKKSDKALYLQIADAIINAVKSGKLTSGNALPGSRQLAGLLNVNRNTVIEALDVLIAEGWLITVDRKGT
FIADILPETNFNKKTETKASSTIENPKPHLVFDDGLPDSRLAPMNDLARAYREIFNRKSRWQIMGYSNELGNVEFRKAIV
QMLNFKRGMNVSLDEICITRGSQMAMYLAAHCLLSKGDSVIIENPGYKPAWEAFENAGATLLPVNILKDGLDLEEVENHL
KNNKAIKAIYVTPHHQFPTTVTMSLKKRLKLIELSNQYGFTIIEDDYDNEFHFGQRPILPISSYSNAKNFIYIGTLSKIV
APALRIGYLAASIENIQKIAQHRKIIDVQGDNIMEEAVLNLINEGKIKRHLKKTNLIYKAKRDHFEKLCKLHLKDKITFT
KPEGGMAFWIVPKSEIDLQKVCNELLKKGIKIMSPEKFSFGNPASGLRLGYASLTEEQMEEGILSLSKYL

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=314, Percent_Identity=23.2484076433121, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI33469970, Length=314, Percent_Identity=23.2484076433121, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1787710, Length=470, Percent_Identity=24.6808510638298, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1790797, Length=459, Percent_Identity=22.2222222222222, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI21356535, Length=337, Percent_Identity=22.8486646884273, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53073; Mature: 53073

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPWQFEIHLDKKSDKALYLQIADAIINAVKSGKLTSGNALPGSRQLAGLLNVNRNTVI
CCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHH
EALDVLIAEGWLITVDRKGTFIADILPETNFNKKTETKASSTIENPKPHLVFDDGLPDSR
HHHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCCHHHHCCCCCCCCEEECCCCCCCC
LAPMNDLARAYREIFNRKSRWQIMGYSNELGNVEFRKAIVQMLNFKRGMNVSLDEICITR
CCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCC
GSQMAMYLAAHCLLSKGDSVIIENPGYKPAWEAFENAGATLLPVNILKDGLDLEEVENHL
CCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCEEEEHHHHHCCCCHHHHHHHH
KNNKAIKAIYVTPHHQFPTTVTMSLKKRLKLIELSNQYGFTIIEDDYDNEFHFGQRPILP
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCCCCCCCEE
ISSYSNAKNFIYIGTLSKIVAPALRIGYLAASIENIQKIAQHRKIIDVQGDNIMEEAVLN
ECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHH
LINEGKIKRHLKKTNLIYKAKRDHFEKLCKLHLKDKITFTKPEGGMAFWIVPKSEIDLQK
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEEECCCCCHHH
VCNELLKKGIKIMSPEKFSFGNPASGLRLGYASLTEEQMEEGILSLSKYL
HHHHHHHCCCEECCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRPWQFEIHLDKKSDKALYLQIADAIINAVKSGKLTSGNALPGSRQLAGLLNVNRNTVI
CCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHH
EALDVLIAEGWLITVDRKGTFIADILPETNFNKKTETKASSTIENPKPHLVFDDGLPDSR
HHHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCCHHHHCCCCCCCCEEECCCCCCCC
LAPMNDLARAYREIFNRKSRWQIMGYSNELGNVEFRKAIVQMLNFKRGMNVSLDEICITR
CCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCC
GSQMAMYLAAHCLLSKGDSVIIENPGYKPAWEAFENAGATLLPVNILKDGLDLEEVENHL
CCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCEEEEHHHHHCCCCHHHHHHHH
KNNKAIKAIYVTPHHQFPTTVTMSLKKRLKLIELSNQYGFTIIEDDYDNEFHFGQRPILP
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCCCCCCCEE
ISSYSNAKNFIYIGTLSKIVAPALRIGYLAASIENIQKIAQHRKIIDVQGDNIMEEAVLN
ECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHH
LINEGKIKRHLKKTNLIYKAKRDHFEKLCKLHLKDKITFTKPEGGMAFWIVPKSEIDLQK
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEEECCCCCHHH
VCNELLKKGIKIMSPEKFSFGNPASGLRLGYASLTEEQMEEGILSLSKYL
HHHHHHHCCCEECCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]