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The map label for this gene is nadA [H]

Identifier: 146301791

GI number: 146301791

Start: 4840220

End: 4841152

Strand: Direct

Name: nadA [H]

Synonym: Fjoh_4055

Alternate gene names: 146301791

Gene position: 4840220-4841152 (Clockwise)

Preceding gene: 146301789

Following gene: 146301792

Centisome position: 79.39

GC content: 36.87

Gene sequence:

>933_bases
ATGGACAAAAAATTTTTGATACAGGAAATCATCCGCTTAAAACAAGAAAAAAATGCTGTAATTCTGGCTCATTATTATCA
AAATGAGGAAATTCAGGAAATAGCAGATTTTATTGGAGACAGTCTTGAATTATCAAAAAAAGCACAAAATACAAATGCCG
ATGTTATTGTTTTTGCCGGAGTTCACTTTATGGCAGAAACTGCCAAAATATTAAATCCTGACAAAAAAGTTGTACTTCCG
GATTTCAACGCAGGATGTTCTCTCGCTGACGGCTGCAATCCTAAAGATTTTAAATTATTTAAAGAAAAATATCCTGATCA
TGTTGTTGTAACTTACATCAACTGTTCTGCCGAAATAAAAGCAATGAGCGATTTGGTCTGCACTTCATCAAACGCAGCAA
AAATTATTGGTTCTATTCCTTCTGATAAAGAAATCATTTTTGCACCCGATAAAAATTTAGGCAGTTATTTAAAAAAAGAA
ACACAACGCGAACTAATCCTCTGGGATGGATCTTGTGTAGTTCACGAAGCCTTTTCGCTGGATAAACTAGTCGAAATTTA
CAATAAAAATCCAAACGCAAAAATTGCGGCACATCCGGAATCTGAAAGTCATATCTTAAAAGCAGCACATTACATTGGCT
CTACTTCCGGCATTATTAATTTTATTAAAACGGATCCTGCTGCCGTTTTCATTGTGGCTACAGAAGCCGGTATCCTGCAT
GAGCTTTCAAAAGCGGTACCCGAAAAAACGCTGATTCCGGCTCCTTCCACAGAAGATAACACTTGCGCCTGCAGCGAATG
TGCTTTCATGAAAGTCAATACTCTTGAAAAATTGTATTGGTGTCTGAAAAACGAAAGCCCGGAAATCCTGGTAAACGAAC
CGTTAAGGATCGAAGCACTGAAACCTATACAAAGAATGCTTGAATTGTCTTAA

Upstream 100 bases:

>100_bases
GCATTTCGAAAAACAAATTTCAATAAAAACCACAAACTTTCTCAACAGCAGTATTTCATTAAAAAATGGGCTTTGCTGTT
GAAAAAACAAGACTTTAATA

Downstream 100 bases:

>100_bases
ACTTAAAAACAAAGAAAATGCTTAAAACAGATATACTTATAGTAGGTTCTGGTATTTCGGGATTATTTCTTGCCATGAAA
ACAGCAAAAAAACGTCCTGA

Product: quinolinate synthetase complex subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDKKFLIQEIIRLKQEKNAVILAHYYQNEEIQEIADFIGDSLELSKKAQNTNADVIVFAGVHFMAETAKILNPDKKVVLP
DFNAGCSLADGCNPKDFKLFKEKYPDHVVVTYINCSAEIKAMSDLVCTSSNAAKIIGSIPSDKEIIFAPDKNLGSYLKKE
TQRELILWDGSCVVHEAFSLDKLVEIYNKNPNAKIAAHPESESHILKAAHYIGSTSGIINFIKTDPAAVFIVATEAGILH
ELSKAVPEKTLIPAPSTEDNTCACSECAFMKVNTLEKLYWCLKNESPEILVNEPLRIEALKPIQRMLELS

Sequences:

>Translated_310_residues
MDKKFLIQEIIRLKQEKNAVILAHYYQNEEIQEIADFIGDSLELSKKAQNTNADVIVFAGVHFMAETAKILNPDKKVVLP
DFNAGCSLADGCNPKDFKLFKEKYPDHVVVTYINCSAEIKAMSDLVCTSSNAAKIIGSIPSDKEIIFAPDKNLGSYLKKE
TQRELILWDGSCVVHEAFSLDKLVEIYNKNPNAKIAAHPESESHILKAAHYIGSTSGIINFIKTDPAAVFIVATEAGILH
ELSKAVPEKTLIPAPSTEDNTCACSECAFMKVNTLEKLYWCLKNESPEILVNEPLRIEALKPIQRMLELS
>Mature_310_residues
MDKKFLIQEIIRLKQEKNAVILAHYYQNEEIQEIADFIGDSLELSKKAQNTNADVIVFAGVHFMAETAKILNPDKKVVLP
DFNAGCSLADGCNPKDFKLFKEKYPDHVVVTYINCSAEIKAMSDLVCTSSNAAKIIGSIPSDKEIIFAPDKNLGSYLKKE
TQRELILWDGSCVVHEAFSLDKLVEIYNKNPNAKIAAHPESESHILKAAHYIGSTSGIINFIKTDPAAVFIVATEAGILH
ELSKAVPEKTLIPAPSTEDNTCACSECAFMKVNTLEKLYWCLKNESPEILVNEPLRIEALKPIQRMLELS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=318, Percent_Identity=41.1949685534591, Blast_Score=246, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34441; Mature: 34441

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKFLIQEIIRLKQEKNAVILAHYYQNEEIQEIADFIGDSLELSKKAQNTNADVIVFAG
CCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEC
VHFMAETAKILNPDKKVVLPDFNAGCSLADGCNPKDFKLFKEKYPDHVVVTYINCSAEIK
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCHHH
AMSDLVCTSSNAAKIIGSIPSDKEIIFAPDKNLGSYLKKETQRELILWDGSCVVHEAFSL
HHHHHHCCCCCCHHEEECCCCCCEEEECCCCCHHHHHHHHCCCEEEEECCCEEEEHHHHH
DKLVEIYNKNPNAKIAAHPESESHILKAAHYIGSTSGIINFIKTDPAAVFIVATEAGILH
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCHHEEEEECCCEEEEEEEECCHHHH
ELSKAVPEKTLIPAPSTEDNTCACSECAFMKVNTLEKLYWCLKNESPEILVNEPLRIEAL
HHHHHCCCCEECCCCCCCCCCEECCCCCEEEHHHHHHHHHHHCCCCCCEEECCCEEEHHH
KPIQRMLELS
HHHHHHHCCC
>Mature Secondary Structure
MDKKFLIQEIIRLKQEKNAVILAHYYQNEEIQEIADFIGDSLELSKKAQNTNADVIVFAG
CCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEC
VHFMAETAKILNPDKKVVLPDFNAGCSLADGCNPKDFKLFKEKYPDHVVVTYINCSAEIK
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCHHH
AMSDLVCTSSNAAKIIGSIPSDKEIIFAPDKNLGSYLKKETQRELILWDGSCVVHEAFSL
HHHHHHCCCCCCHHEEECCCCCCEEEECCCCCHHHHHHHHCCCEEEEECCCEEEEHHHHH
DKLVEIYNKNPNAKIAAHPESESHILKAAHYIGSTSGIINFIKTDPAAVFIVATEAGILH
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCHHEEEEECCCEEEEEEEECCHHHH
ELSKAVPEKTLIPAPSTEDNTCACSECAFMKVNTLEKLYWCLKNESPEILVNEPLRIEAL
HHHHHCCCCEECCCCCCCCCCEECCCCCEEEHHHHHHHHHHHCCCCCCEEECCCEEEHHH
KPIQRMLELS
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA